Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Probable ubiquitin carboxyl-terminal hydrolase FAF-X (Homo sapiens (Human)) | BDBM50447833 (CHEMBL3114085) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas M.D. Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal His6-Smt3-fusion-tagged Usp9x catalytic domain expressed in Escherichia coli using Ub-AMC as substrate inc... | Bioorg Med Chem 22: 1450-8 (2014) Article DOI: 10.1016/j.bmc.2013.12.048 BindingDB Entry DOI: 10.7270/Q2BP0499 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (Homo sapiens (Human)) | BDBM50437695 (CHEMBL1923233) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Agriculture Curated by ChEMBL | Assay Description Inhibition of USP9x in human Z138 cells after 1 hr by immunoblotting analysis | Bioorg Med Chem Lett 23: 4328-31 (2013) Article DOI: 10.1016/j.bmcl.2013.05.093 BindingDB Entry DOI: 10.7270/Q2T15528 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (Homo sapiens (Human)) | BDBM50437695 (CHEMBL1923233) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Texas M.D. Anderson Cancer Center Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminal His6-Smt3-fusion-tagged Usp9x catalytic domain expressed in Escherichia coli using Ub-AMC as substrate inc... | Bioorg Med Chem 22: 1450-8 (2014) Article DOI: 10.1016/j.bmc.2013.12.048 BindingDB Entry DOI: 10.7270/Q2BP0499 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (Homo sapiens (Human)) | BDBM50538571 (CHEMBL4635160) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
RAPT Therapeutics, Inc. Curated by ChEMBL | Assay Description Inhibition of human GST-tagged USP9X CD (1554 to 1995 residues) expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine ... | J Med Chem 63: 5398-5420 (2020) Article DOI: 10.1021/acs.jmedchem.0c00245 BindingDB Entry DOI: 10.7270/Q2XK8K2T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Probable ubiquitin carboxyl-terminal hydrolase FAF-X (Homo sapiens (Human)) | BDBM50548233 (CHEMBL4756029) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of USP9 (unknown origin) | Citation and Details Article DOI: 10.1016/j.bmcl.2018.05.013 BindingDB Entry DOI: 10.7270/Q2NK3JNN | |||||||||||
More data for this Ligand-Target Pair |