BindingDB PrimarySearch

Found 10 hits of ic50 data for polymerid = 50006428
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (Homo sapiens (Human))	BDBM50440527 (CHEMBL2426164) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of WRN (unknown origin) by gel-based DNA unwinding assay				Bioorg Med Chem Lett 23: 5660-6 (2013) Checked by Author Article DOI: 10.1016/j.bmcl.2013.08.025 BindingDB Entry DOI: 10.7270/Q2KK9D78
					More data for this Ligand-Target Pair
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (Homo sapiens (Human))	BDBM50440514 (CHEMBL2426190) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of WRN (unknown origin) by gel-based DNA unwinding assay				Bioorg Med Chem Lett 23: 5660-6 (2013) Checked by Author Article DOI: 10.1016/j.bmcl.2013.08.025 BindingDB Entry DOI: 10.7270/Q2KK9D78
					More data for this Ligand-Target Pair
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (Homo sapiens (Human))	BDBM50440533 (CHEMBL2426169) Show SMILES Fc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C#N Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of WRN (unknown origin) by gel-based DNA unwinding assay				Bioorg Med Chem Lett 23: 5660-6 (2013) Checked by Author Article DOI: 10.1016/j.bmcl.2013.08.025 BindingDB Entry DOI: 10.7270/Q2KK9D78
					More data for this Ligand-Target Pair
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (Homo sapiens (Human))	BDBM50440531 (CHEMBL2426168) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of WRN (unknown origin) by gel-based DNA unwinding assay				Bioorg Med Chem Lett 23: 5660-6 (2013) Checked by Author Article DOI: 10.1016/j.bmcl.2013.08.025 BindingDB Entry DOI: 10.7270/Q2KK9D78
					More data for this Ligand-Target Pair
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (Homo sapiens (Human))	BDBM50440524 (CHEMBL2426161) Show SMILES Brc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1Br Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of WRN (unknown origin) by gel-based DNA unwinding assay				Bioorg Med Chem Lett 23: 5660-6 (2013) Checked by Author Article DOI: 10.1016/j.bmcl.2013.08.025 BindingDB Entry DOI: 10.7270/Q2KK9D78
					More data for this Ligand-Target Pair
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (Homo sapiens (Human))	BDBM50044626 (CHEMBL1374426) Show SMILES CCC(=O)OCN1C(=O)C=CC1=O \|c:9\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of recombinant WRN (unknown origin) helicase activity expressed in baculovirus expression system using forked duplex DNA as substrate afte...				J Med Chem 60: 2169-2192 (2017) Article DOI: 10.1021/acs.jmedchem.6b00966 BindingDB Entry DOI: 10.7270/Q2CR5WMB
University of Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (Homo sapiens (Human))	BDBM48721 (1-(3,4-Dichloro-phenyl)-3-(5-pyridin-4-yl-[1,3,4]t...) Show SMILES Clc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1Cl Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of WRN (unknown origin) by gel-based DNA unwinding assay				Bioorg Med Chem Lett 23: 5660-6 (2013) Checked by Author Article DOI: 10.1016/j.bmcl.2013.08.025 BindingDB Entry DOI: 10.7270/Q2KK9D78
					More data for this Ligand-Target Pair
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (Homo sapiens (Human))	BDBM50440531 (CHEMBL2426168) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Drexel University College of Medicine Curated by ChEMBL					Assay Description Inhibition of WRN helicase (unknown origin)				Bioorg Med Chem Lett 24: 3006-13 (2014) Article DOI: 10.1016/j.bmcl.2014.04.088 BindingDB Entry DOI: 10.7270/Q2NV9KW7
Drexel University College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (Homo sapiens (Human))	BDBM50440538 (CHEMBL2426174) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Center for Advancing Translational Sciences Curated by ChEMBL					Assay Description Inhibition of WRN (unknown origin) by gel-based DNA unwinding assay				Bioorg Med Chem Lett 23: 5660-6 (2013) Checked by Author Article DOI: 10.1016/j.bmcl.2013.08.025 BindingDB Entry DOI: 10.7270/Q2KK9D78
					More data for this Ligand-Target Pair
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (Homo sapiens (Human))	BDBM50044626 (CHEMBL1374426) Show SMILES CCC(=O)OCN1C(=O)C=CC1=O \|c:9\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Drexel University College of Medicine Curated by ChEMBL					Assay Description Inhibition of WRN helicase (unknown origin)				Bioorg Med Chem Lett 24: 3006-13 (2014) Article DOI: 10.1016/j.bmcl.2014.04.088 BindingDB Entry DOI: 10.7270/Q2NV9KW7
Drexel University College of Medicine Curated by ChEMBL					More data for this Ligand-Target Pair