Found 15 hits of ki data for polymerid = 50006441 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Transcription factor 7-like 2
(Homo sapiens (Human)) | BDBM50014098
(CHEMBL3260852)Show InChI InChI=1S/C10H9N5O2/c16-10-7-3-1-6(5-8(7)17-13-10)2-4-9-11-14-15-12-9/h1,3,5H,2,4H2,(H,13,16)(H,11,12,14,15) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of beta-catenin/T cell factor (unknown origin) |
Bioorg Med Chem Lett 24: 2546-54 (2014)
Article DOI: 10.1016/j.bmcl.2014.03.095
BindingDB Entry DOI: 10.7270/Q2FX7C05 |
More data for this
Ligand-Target Pair | |
Transcription factor 7-like 2
(Homo sapiens (Human)) | BDBM50014132
(CHEMBL2323032)Show InChI InChI=1S/C10H10N6O/c17-16-9-3-1-7(5-8(9)6-11-16)2-4-10-12-14-15-13-10/h1,3,5-6,17H,2,4H2,(H,12,13,14,15) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assay |
ACS Med Chem Lett 4: 306-11 (2013)
Article DOI: 10.1021/ml300367f
BindingDB Entry DOI: 10.7270/Q2CN76TG |
More data for this
Ligand-Target Pair | |
Transcription factor 7-like 2
(Homo sapiens (Human)) | BDBM32102
(1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,...)Show InChI InChI=1S/C7H7N5O2/c1-11-6(13)4-5(10-7(11)14)12(2)9-3-8-4/h3H,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay |
ACS Med Chem Lett 4: 306-11 (2013)
Article DOI: 10.1021/ml300367f
BindingDB Entry DOI: 10.7270/Q2CN76TG |
More data for this
Ligand-Target Pair | |
Transcription factor 7-like 2
(Homo sapiens (Human)) | BDBM50014132
(CHEMBL2323032)Show InChI InChI=1S/C10H10N6O/c17-16-9-3-1-7(5-8(9)6-11-16)2-4-10-12-14-15-13-10/h1,3,5-6,17H,2,4H2,(H,12,13,14,15) | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay |
ACS Med Chem Lett 4: 306-11 (2013)
Article DOI: 10.1021/ml300367f
BindingDB Entry DOI: 10.7270/Q2CN76TG |
More data for this
Ligand-Target Pair | |
Transcription factor 7-like 2
(Homo sapiens (Human)) | BDBM32102
(1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,...)Show InChI InChI=1S/C7H7N5O2/c1-11-6(13)4-5(10-7(11)14)12(2)9-3-8-4/h3H,1-2H3 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
KEGG
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| 5.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assay |
ACS Med Chem Lett 4: 306-11 (2013)
Article DOI: 10.1021/ml300367f
BindingDB Entry DOI: 10.7270/Q2CN76TG |
More data for this
Ligand-Target Pair | |
Transcription factor 7-like 2
(Homo sapiens (Human)) | BDBM50094484
(CHEBI:3556 | CHEMBL2323033 | US9284299, CGP049090 ...)Show SMILES COc1c(C[C@H](C)O)c2c3c(C[C@H](C)O)c(OC)c(=O)c4c(O)cc5OCOc6cc(O)c(c2c6c5c34)c1=O |r| Show InChI InChI=1S/C27H29NO3/c29-26(27(30,23-12-6-2-7-13-23)24-14-8-3-9-15-24)31-25-17-20-28(21-18-25)19-16-22-10-4-1-5-11-22/h1-15,25,30H,16-21H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay |
ACS Med Chem Lett 4: 306-11 (2013)
Article DOI: 10.1021/ml300367f
BindingDB Entry DOI: 10.7270/Q2CN76TG |
More data for this
Ligand-Target Pair | |
Transcription factor 7-like 2
(Homo sapiens (Human)) | BDBM50094600
(CHEMBL2323029)Show SMILES OC(=O)c1ccc2nc(-c3ccc(Cl)cc3)c(nc2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H27N5/c1-16-17(2)29(18(3)19-10-6-4-7-11-19)24-21(16)23(26-15-14-25)27-22(28-24)20-12-8-5-9-13-20/h4-13,18H,14-15,25H2,1-3H3,(H,26,27,28)/t18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assay |
ACS Med Chem Lett 4: 306-11 (2013)
Article DOI: 10.1021/ml300367f
BindingDB Entry DOI: 10.7270/Q2CN76TG |
More data for this
Ligand-Target Pair | |
Transcription factor 7-like 2
(Homo sapiens (Human)) | BDBM50094600
(CHEMBL2323029)Show SMILES OC(=O)c1ccc2nc(-c3ccc(Cl)cc3)c(nc2c1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C24H27N5/c1-16-17(2)29(18(3)19-10-6-4-7-11-19)24-21(16)23(26-15-14-25)27-22(28-24)20-12-8-5-9-13-20/h4-13,18H,14-15,25H2,1-3H3,(H,26,27,28)/t18-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay |
ACS Med Chem Lett 4: 306-11 (2013)
Article DOI: 10.1021/ml300367f
BindingDB Entry DOI: 10.7270/Q2CN76TG |
More data for this
Ligand-Target Pair | |
Transcription factor 7-like 2
(Homo sapiens (Human)) | BDBM50489463
(CHEMBL2323031)Show SMILES OC(=O)c1cccc(NC(=O)C(=O)N\N=C2/C(=O)N(CC=C)c3ccccc23)c1 Show InChI InChI=1S/C20H16N4O5/c1-2-10-24-15-9-4-3-8-14(15)16(19(24)27)22-23-18(26)17(25)21-13-7-5-6-12(11-13)20(28)29/h2-9,11H,1,10H2,(H,21,25)(H,23,26)(H,28,29)/b22-16- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assay |
ACS Med Chem Lett 4: 306-11 (2013)
Article DOI: 10.1021/ml300367f
BindingDB Entry DOI: 10.7270/Q2CN76TG |
More data for this
Ligand-Target Pair | |
Transcription factor 7-like 2
(Homo sapiens (Human)) | BDBM50249236
((R)-1-(4,9-dihydroxy-12-((R)-2-((4-hydroxyphenoxy)...)Show SMILES COc1cc(=O)c2c(O)c(OC)c(C[C@@H](C)OC(=O)Oc3ccc(O)cc3)c3c4c(C[C@@H](C)OC(=O)c5ccccc5)c(OC)c(O)c5c4c(c(OC)cc5=O)c1c23 |r| Show InChI InChI=1S/C44H38O14/c1-20(56-43(50)22-10-8-7-9-11-22)16-25-31-32-26(17-21(2)57-44(51)58-24-14-12-23(45)13-15-24)42(55-6)40(49)34-28(47)19-30(53-4)36(38(32)34)35-29(52-3)18-27(46)33(37(31)35)39(48)41(25)54-5/h7-15,18-21,45,48-49H,16-17H2,1-6H3/t20-,21-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assay |
ACS Med Chem Lett 4: 306-11 (2013)
Article DOI: 10.1021/ml300367f
BindingDB Entry DOI: 10.7270/Q2CN76TG |
More data for this
Ligand-Target Pair | |
Transcription factor 7-like 2
(Homo sapiens (Human)) | BDBM50094597
(CHEMBL2323028)Show InChI InChI=1S/C30H30N4/c1-20-22(3)34(23(4)25-16-10-6-11-17-25)30-27(20)29(31-21(2)24-14-8-5-9-15-24)32-28(33-30)26-18-12-7-13-19-26/h5-19,21,23H,1-4H3,(H,31,32,33)/t21-,23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay |
ACS Med Chem Lett 4: 306-11 (2013)
Article DOI: 10.1021/ml300367f
BindingDB Entry DOI: 10.7270/Q2CN76TG |
More data for this
Ligand-Target Pair | |
Transcription factor 7-like 2
(Homo sapiens (Human)) | BDBM50489463
(CHEMBL2323031)Show SMILES OC(=O)c1cccc(NC(=O)C(=O)N\N=C2/C(=O)N(CC=C)c3ccccc23)c1 Show InChI InChI=1S/C20H16N4O5/c1-2-10-24-15-9-4-3-8-14(15)16(19(24)27)22-23-18(26)17(25)21-13-7-5-6-12(11-13)20(28)29/h2-9,11H,1,10H2,(H,21,25)(H,23,26)(H,28,29)/b22-16- | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay |
ACS Med Chem Lett 4: 306-11 (2013)
Article DOI: 10.1021/ml300367f
BindingDB Entry DOI: 10.7270/Q2CN76TG |
More data for this
Ligand-Target Pair | |
Transcription factor 7-like 2
(Homo sapiens (Human)) | BDBM50489464
(CHEMBL2323030)Show InChI InChI=1S/C15H15NO5S2/c1-20-10-5-3-4-9(13(10)21-2)8-11-14(19)16(15(22)23-11)7-6-12(17)18/h3-5,8H,6-7H2,1-2H3,(H,17,18)/b11-8+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
PC cid
PC sid
UniChem
| Article
PubMed
| 2.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of human beta-casein/Tcf4 interaction after 1 hr by alphascreen assay |
ACS Med Chem Lett 4: 306-11 (2013)
Article DOI: 10.1021/ml300367f
BindingDB Entry DOI: 10.7270/Q2CN76TG |
More data for this
Ligand-Target Pair | |
Transcription factor 7-like 2
(Homo sapiens (Human)) | BDBM50094484
(CHEBI:3556 | CHEMBL2323033 | US9284299, CGP049090 ...)Show SMILES COc1c(C[C@H](C)O)c2c3c(C[C@H](C)O)c(OC)c(=O)c4c(O)cc5OCOc6cc(O)c(c2c6c5c34)c1=O |r| Show InChI InChI=1S/C27H29NO3/c29-26(27(30,23-12-6-2-7-13-23)24-14-8-3-9-15-24)31-25-17-20-28(21-18-25)19-16-22-10-4-1-5-11-22/h1-15,25,30H,16-21H2 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assay |
ACS Med Chem Lett 4: 306-11 (2013)
Article DOI: 10.1021/ml300367f
BindingDB Entry DOI: 10.7270/Q2CN76TG |
More data for this
Ligand-Target Pair | |
Transcription factor 7-like 2
(Homo sapiens (Human)) | BDBM50094597
(CHEMBL2323028)Show InChI InChI=1S/C30H30N4/c1-20-22(3)34(23(4)25-16-10-6-11-17-25)30-27(20)29(31-21(2)24-14-8-5-9-15-24)32-28(33-30)26-18-12-7-13-19-26/h5-19,21,23H,1-4H3,(H,31,32,33)/t21-,23-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Utah
Curated by ChEMBL
| Assay Description
Inhibition of human beta-casein/Tcf4 interaction after 1 hr by fluorescence polarization assay |
ACS Med Chem Lett 4: 306-11 (2013)
Article DOI: 10.1021/ml300367f
BindingDB Entry DOI: 10.7270/Q2CN76TG |
More data for this
Ligand-Target Pair | |
Search and Browse
