Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sterol O-acyltransferase 1 (Cricetulus griseus) | BDBM50051901 (1-[5-(4,5-Diphenyl-1H-imidazol-2-ylsulfanyl)-penty...) | PDB MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Concentration required for the inhibition of Cholesterol O-acyl transferase from hamster liver | Bioorg Med Chem Lett 2: 375-380 (1992) Article DOI: 10.1016/S0960-894X(00)80149-3 BindingDB Entry DOI: 10.7270/Q2MP535G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Cricetulus griseus) | BDBM50242257 (2-((1R,2S,4aS)-1,2,4a,5-Tetramethyl-1,2,3,4,4a,7,8...) | PDB MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of SOAT1 in CHO cell microsomal fraction using [1-14C]oleoyl-CoA as substrate measured after 5 mins by TLC based method | Bioorg Med Chem Lett 29: 2283-2285 (2019) Article DOI: 10.1016/j.bmcl.2019.06.026 BindingDB Entry DOI: 10.7270/Q2NK3JC2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 1 (Cricetulus griseus) | BDBM50196069 (CHEMBL3965313) | PDB MMDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of SOAT1 in CHO cell microsomal fraction using [1-14C]oleoyl-CoA as substrate measured after 5 mins by TLC based method | Bioorg Med Chem Lett 29: 2283-2285 (2019) Article DOI: 10.1016/j.bmcl.2019.06.026 BindingDB Entry DOI: 10.7270/Q2NK3JC2 | |||||||||||
More data for this Ligand-Target Pair |