Compile Data Set for Download or QSAR

Found 61 hits of kd data for polymerid = 50006606   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Elongin-C (Homo sapiens (Human))	BDBM50463158 (CHEMBL4244103) Show SMILES OCc1ccc(cc1)-n1cccc1 Show InChI InChI=1S/C11H11NO/c13-9-10-3-5-11(6-4-10)12-7-1-2-8-12/h1-8,13H,9H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to N-terminal His6 tagged VHL (54 to 213 residues)/ELoC (17 to 112 residues)/EloB (1 to 120 residues) (unknown origin) complex expre...				J Med Chem 61: 7387-7393 (2018) Article DOI: 10.1021/acs.jmedchem.8b00842 BindingDB Entry DOI: 10.7270/Q2639SCC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50463159 (CHEMBL4241500) Show SMILES Clc1ccc2SCCC(=O)c2c1 Show InChI InChI=1S/C9H7ClOS/c10-6-1-2-9-7(5-6)8(11)3-4-12-9/h1-2,5H,3-4H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to N-terminal His6 tagged VHL (54 to 213 residues)/ELoC (17 to 112 residues)/EloB (1 to 120 residues) (unknown origin) complex expre...				J Med Chem 61: 7387-7393 (2018) Article DOI: 10.1021/acs.jmedchem.8b00842 BindingDB Entry DOI: 10.7270/Q2639SCC
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459943 (CHEMBL4225470) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(F)CC2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C26H33FN4O4S/c1-15-20(36-14-29-15)17-7-5-16(6-8-17)12-28-22(33)19-11-18(32)13-31(19)23(34)21(25(2,3)4)30-24(35)26(27)9-10-26/h5-8,14,18-19,21,32H,9-13H2,1-4H3,(H,28,33)(H,30,35)/t18-,19+,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VBC (unknown origin) at 50 uM at 20 degC by surface plasmon resonance assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459943 (CHEMBL4225470) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(F)CC2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C26H33FN4O4S/c1-15-20(36-14-29-15)17-7-5-16(6-8-17)12-28-22(33)19-11-18(32)13-31(19)23(34)21(25(2,3)4)30-24(35)26(27)9-10-26/h5-8,14,18-19,21,32H,9-13H2,1-4H3,(H,28,33)(H,30,35)/t18-,19+,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VBC (unknown origin) at 50 uM at 10 degC by surface plasmon resonance assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459943 (CHEMBL4225470) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(F)CC2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C26H33FN4O4S/c1-15-20(36-14-29-15)17-7-5-16(6-8-17)12-28-22(33)19-11-18(32)13-31(19)23(34)21(25(2,3)4)30-24(35)26(27)9-10-26/h5-8,14,18-19,21,32H,9-13H2,1-4H3,(H,28,33)(H,30,35)/t18-,19+,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VHL (unknown origin)/elongin C (unknown origin)/elongin B (unknown origin) by isothermal titration calorimetry-based assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459944 (CHEMBL4225537) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(CC2)C#N)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C27H33N5O4S/c1-16-21(37-15-30-16)18-7-5-17(6-8-18)12-29-23(34)20-11-19(33)13-32(20)24(35)22(26(2,3)4)31-25(36)27(14-28)9-10-27/h5-8,15,19-20,22,33H,9-13H2,1-4H3,(H,29,34)(H,31,36)/t19-,20+,22-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VBC (unknown origin) at 50 uM at 20 degC by surface plasmon resonance assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50604004 (CHEMBL5205396) Show SMILES C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)CCCCCCCCN1CCN(CC1)c1cc(Cl)cc2n(Cc3cc(C)c(F)c(C)c3)c(nc12)N1CC2(CNC2)C1)C(C)(C)C)c1ccc(cc1)-c1scnc1C |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01774 BindingDB Entry DOI: 10.7270/Q2CF9V6Z
					More data for this Ligand-Target Pair
Elongin-C (Homo sapiens (Human))	BDBM50459880 (CHEMBL4226570) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCNC(=O)C[C@@H]2N=C(c3c(C)c(C)sc3-n3c(C)nnc23)c2ccc(Cl)cc2)C(C)(C)C)cc1 |r,c:43| Show InChI InChI=1S/C49H60ClN9O8S2/c1-28-30(3)69-48-41(28)42(33-12-14-35(50)15-13-33)54-37(45-57-56-31(4)59(45)48)23-39(61)51-16-17-65-18-19-66-20-21-67-26-40(62)55-44(49(5,6)7)47(64)58-25-36(60)22-38(58)46(63)52-24-32-8-10-34(11-9-32)43-29(2)53-27-68-43/h8-15,27,36-38,44,60H,16-26H2,1-7H3,(H,51,61)(H,52,63)(H,55,62)/t36-,37+,38+,44-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to N-terminal His6-tagged recombinant human VHL (54 to 213 residues)/elongin C (17 to 112 residues)/elongin B (1 to 104 residues) ex...				J Med Chem 61: 504-513 (2018) Article DOI: 10.1021/acs.jmedchem.6b01912 BindingDB Entry DOI: 10.7270/Q2R49TC3
					More data for this Ligand-Target Pair
Elongin-C (Homo sapiens (Human))	BDBM50459879 (CHEMBL4227226) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCNC(=O)C[C@@H]2N=C(c3c(C)c(C)sc3-n3c(C)nnc23)c2ccc(Cl)cc2)C(C)(C)C)cc1 |r,c:46| Show InChI InChI=1S/C51H64ClN9O9S2/c1-30-32(3)72-50-43(30)44(35-12-14-37(52)15-13-35)56-39(47-59-58-33(4)61(47)50)25-41(63)53-16-17-67-18-19-68-20-21-69-22-23-70-28-42(64)57-46(51(5,6)7)49(66)60-27-38(62)24-40(60)48(65)54-26-34-8-10-36(11-9-34)45-31(2)55-29-71-45/h8-15,29,38-40,46,62H,16-28H2,1-7H3,(H,53,63)(H,54,65)(H,57,64)/t38-,39+,40+,46-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to N-terminal His6-tagged recombinant human VHL (54 to 213 residues)/elongin C (17 to 112 residues)/elongin B (1 to 104 residues) ex...				J Med Chem 61: 504-513 (2018) Article DOI: 10.1021/acs.jmedchem.6b01912 BindingDB Entry DOI: 10.7270/Q2R49TC3
					More data for this Ligand-Target Pair
Elongin-C (Homo sapiens (Human))	BDBM50459944 (CHEMBL4225537) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(CC2)C#N)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C27H33N5O4S/c1-16-21(37-15-30-16)18-7-5-17(6-8-18)12-29-23(34)20-11-19(33)13-32(20)24(35)22(26(2,3)4)31-25(36)27(14-28)9-10-27/h5-8,15,19-20,22,33H,9-13H2,1-4H3,(H,29,34)(H,31,36)/t19-,20+,22-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459944 (CHEMBL4225537) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(CC2)C#N)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C27H33N5O4S/c1-16-21(37-15-30-16)18-7-5-17(6-8-18)12-29-23(34)20-11-19(33)13-32(20)24(35)22(26(2,3)4)31-25(36)27(14-28)9-10-27/h5-8,15,19-20,22,33H,9-13H2,1-4H3,(H,29,34)(H,31,36)/t19-,20+,22-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VHL (unknown origin)/elongin C (unknown origin)/elongin B (unknown origin) by isothermal titration calorimetry-based assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459943 (CHEMBL4225470) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(F)CC2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C26H33FN4O4S/c1-15-20(36-14-29-15)17-7-5-16(6-8-17)12-28-22(33)19-11-18(32)13-31(19)23(34)21(25(2,3)4)30-24(35)26(27)9-10-26/h5-8,14,18-19,21,32H,9-13H2,1-4H3,(H,28,33)(H,30,35)/t18-,19+,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459954 (CHEMBL4228950) Show SMILES CC(=O)C1(CC1)C(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| Show InChI InChI=1S/C28H36N4O5S/c1-16-22(38-15-30-16)19-8-6-18(7-9-19)13-29-24(35)21-12-20(34)14-32(21)25(36)23(27(3,4)5)31-26(37)28(10-11-28)17(2)33/h6-9,15,20-21,23,34H,10-14H2,1-5H3,(H,29,35)(H,31,37)/t20-,21+,23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VBC (unknown origin) at 50 uM at 20 degC by surface plasmon resonance assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459944 (CHEMBL4225537) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2(CC2)C#N)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C27H33N5O4S/c1-16-21(37-15-30-16)18-7-5-17(6-8-18)12-29-23(34)20-11-19(33)13-32(20)24(35)22(26(2,3)4)31-25(36)27(14-28)9-10-27/h5-8,15,19-20,22,33H,9-13H2,1-4H3,(H,29,34)(H,31,36)/t19-,20+,22-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VBC (unknown origin) at 50 uM at 10 degC by surface plasmon resonance assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459947 (CHEMBL4225856) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CO)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C24H32N4O5S/c1-14-20(34-13-26-14)16-7-5-15(6-8-16)10-25-22(32)18-9-17(30)11-28(18)23(33)21(24(2,3)4)27-19(31)12-29/h5-8,13,17-18,21,29-30H,9-12H2,1-4H3,(H,25,32)(H,27,31)/t17-,18+,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VHL (unknown origin)/elongin C (unknown origin)/elongin B (unknown origin) by isothermal titration calorimetry-based assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459876 (CHEMBL4229193) Show SMILES C[C@H]1C[C@@H](Nc2ccc(Cl)cc2)c2cc(ccc2N1C(C)=O)-c1ccc(cc1)C(=O)NCCOCCOCCOCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| Show InChI InChI=1S/C55H66ClN7O9S/c1-34-27-46(60-43-18-16-42(56)17-19-43)45-28-41(15-20-47(45)63(34)36(3)64)38-11-13-40(14-12-38)52(67)57-21-22-70-23-24-71-25-26-72-32-49(66)61-51(55(4,5)6)54(69)62-31-44(65)29-48(62)53(68)58-30-37-7-9-39(10-8-37)50-35(2)59-33-73-50/h7-20,28,33-34,44,46,48,51,60,65H,21-27,29-32H2,1-6H3,(H,57,67)(H,58,68)(H,61,66)/t34-,44+,46+,48-,51+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to N-terminal His6-tagged recombinant human VHL (54 to 213 residues)/elongin C (17 to 112 residues)/elongin B (1 to 104 residues) ex...				J Med Chem 61: 504-513 (2018) Article DOI: 10.1021/acs.jmedchem.6b01912 BindingDB Entry DOI: 10.7270/Q2R49TC3
					More data for this Ligand-Target Pair
Elongin-C (Homo sapiens (Human))	BDBM50459954 (CHEMBL4228950) Show SMILES CC(=O)C1(CC1)C(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| Show InChI InChI=1S/C28H36N4O5S/c1-16-22(38-15-30-16)19-8-6-18(7-9-19)13-29-24(35)21-12-20(34)14-32(21)25(36)23(27(3,4)5)31-26(37)28(10-11-28)17(2)33/h6-9,15,20-21,23,34H,10-14H2,1-5H3,(H,29,35)(H,31,37)/t20-,21+,23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VHL (unknown origin)/elongin C (unknown origin)/elongin B (unknown origin) by isothermal titration calorimetry-based assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50099062 (CHEMBL3344081 | US10730870, Example 3 | US11512083...) Show SMILES CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| Show InChI InChI=1S/C24H32N4O4S/c1-14-20(33-13-26-14)17-8-6-16(7-9-17)11-25-22(31)19-10-18(30)12-28(19)23(32)21(24(3,4)5)27-15(2)29/h6-9,13,18-19,21,30H,10-12H2,1-5H3,(H,25,31)(H,27,29)/t18-,19+,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VBC (unknown origin) at 50 uM at 20 degC by surface plasmon resonance assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459881 (CHEMBL4226376) Show SMILES C[C@H]1C[C@@H](Nc2ccc(Cl)cc2)c2cc(ccc2N1C(C)=O)-c1ccc(cc1)C(=O)NCCOCCOCCOCCOCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| Show InChI InChI=1S/C57H70ClN7O10S/c1-36-29-48(62-45-18-16-44(58)17-19-45)47-30-43(15-20-49(47)65(36)38(3)66)40-11-13-42(14-12-40)54(69)59-21-22-72-23-24-73-25-26-74-27-28-75-34-51(68)63-53(57(4,5)6)56(71)64-33-46(67)31-50(64)55(70)60-32-39-7-9-41(10-8-39)52-37(2)61-35-76-52/h7-20,30,35-36,46,48,50,53,62,67H,21-29,31-34H2,1-6H3,(H,59,69)(H,60,70)(H,63,68)/t36-,46+,48+,50-,53+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	109	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to N-terminal His6-tagged recombinant human VHL (54 to 213 residues)/elongin C (17 to 112 residues)/elongin B (1 to 104 residues) ex...				J Med Chem 61: 504-513 (2018) Article DOI: 10.1021/acs.jmedchem.6b01912 BindingDB Entry DOI: 10.7270/Q2R49TC3
					More data for this Ligand-Target Pair
Elongin-C (Homo sapiens (Human))	BDBM50459954 (CHEMBL4228950) Show SMILES CC(=O)C1(CC1)C(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| Show InChI InChI=1S/C28H36N4O5S/c1-16-22(38-15-30-16)19-8-6-18(7-9-19)13-29-24(35)21-12-20(34)14-32(21)25(36)23(27(3,4)5)31-26(37)28(10-11-28)17(2)33/h6-9,15,20-21,23,34H,10-14H2,1-5H3,(H,29,35)(H,31,37)/t20-,21+,23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VBC (unknown origin) at 50 uM at 10 degC by surface plasmon resonance assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459878 (CHEMBL4227834) Show SMILES C[C@H]1C[C@@H](Nc2ccc(Cl)cc2)c2cc(ccc2N1C(C)=O)-c1ccc(cc1)C(=O)NCCOCCOCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| Show InChI InChI=1S/C53H62ClN7O8S/c1-32-25-44(58-41-18-16-40(54)17-19-41)43-26-39(15-20-45(43)61(32)34(3)62)36-11-13-38(14-12-36)50(65)55-21-22-68-23-24-69-30-47(64)59-49(53(4,5)6)52(67)60-29-42(63)27-46(60)51(66)56-28-35-7-9-37(10-8-35)48-33(2)57-31-70-48/h7-20,26,31-32,42,44,46,49,58,63H,21-25,27-30H2,1-6H3,(H,55,65)(H,56,66)(H,59,64)/t32-,42+,44+,46-,49+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to N-terminal His6-tagged recombinant human VHL (54 to 213 residues)/elongin C (17 to 112 residues)/elongin B (1 to 104 residues) ex...				J Med Chem 61: 504-513 (2018) Article DOI: 10.1021/acs.jmedchem.6b01912 BindingDB Entry DOI: 10.7270/Q2R49TC3
					More data for this Ligand-Target Pair
Elongin-C (Homo sapiens (Human))	BDBM50099062 (CHEMBL3344081 | US10730870, Example 3 | US11512083...) Show SMILES CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| Show InChI InChI=1S/C24H32N4O4S/c1-14-20(33-13-26-14)17-8-6-16(7-9-17)11-25-22(31)19-10-18(30)12-28(19)23(32)21(24(3,4)5)27-15(2)29/h6-9,13,18-19,21,30H,10-12H2,1-5H3,(H,25,31)(H,27,29)/t18-,19+,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	123	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VBC (unknown origin) at 50 uM at 10 degC by surface plasmon resonance assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459949 (CHEMBL4227893) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2CC2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C26H34N4O4S/c1-15-21(35-14-28-15)17-7-5-16(6-8-17)12-27-24(33)20-11-19(31)13-30(20)25(34)22(26(2,3)4)29-23(32)18-9-10-18/h5-8,14,18-20,22,31H,9-13H2,1-4H3,(H,27,33)(H,29,32)/t19-,20+,22-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VHL (unknown origin)/elongin C (unknown origin)/elongin B (unknown origin) by isothermal titration calorimetry-based assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459955 (CHEMBL4228624) Show SMILES CC(=O)NC1(CC1)C(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| Show InChI InChI=1S/C28H37N5O5S/c1-16-22(39-15-30-16)19-8-6-18(7-9-19)13-29-24(36)21-12-20(35)14-33(21)25(37)23(27(3,4)5)31-26(38)28(10-11-28)32-17(2)34/h6-9,15,20-21,23,35H,10-14H2,1-5H3,(H,29,36)(H,31,38)(H,32,34)/t20-,21+,23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VHL (unknown origin)/elongin C (unknown origin)/elongin B (unknown origin) by isothermal titration calorimetry-based assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459877 (CHEMBL4227158) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCNC(=O)C[C@@H]2N=C(c3c(C)c(C)sc3-n3c(C)nnc23)c2ccc(Cl)cc2)C(C)(C)C)cc1 |r,c:40| Show InChI InChI=1S/C47H56ClN9O7S2/c1-26-28(3)66-46-39(26)40(31-12-14-33(48)15-13-31)52-35(43-55-54-29(4)57(43)46)21-37(59)49-16-17-63-18-19-64-24-38(60)53-42(47(5,6)7)45(62)56-23-34(58)20-36(56)44(61)50-22-30-8-10-32(11-9-30)41-27(2)51-25-65-41/h8-15,25,34-36,42,58H,16-24H2,1-7H3,(H,49,59)(H,50,61)(H,53,60)/t34-,35+,36+,42-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	147	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to N-terminal His6-tagged recombinant human VHL (54 to 213 residues)/elongin C (17 to 112 residues)/elongin B (1 to 104 residues) ex...				J Med Chem 61: 504-513 (2018) Article DOI: 10.1021/acs.jmedchem.6b01912 BindingDB Entry DOI: 10.7270/Q2R49TC3
					More data for this Ligand-Target Pair
Elongin-C (Homo sapiens (Human))	BDBM50099062 (CHEMBL3344081 | US10730870, Example 3 | US11512083...) Show SMILES CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| Show InChI InChI=1S/C24H32N4O4S/c1-14-20(33-13-26-14)17-8-6-16(7-9-17)11-25-22(31)19-10-18(30)12-28(19)23(32)21(24(3,4)5)27-15(2)29/h6-9,13,18-19,21,30H,10-12H2,1-5H3,(H,25,31)(H,27,29)/t18-,19+,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459949 (CHEMBL4227893) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2CC2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C26H34N4O4S/c1-15-21(35-14-28-15)17-7-5-16(6-8-17)12-27-24(33)20-11-19(31)13-30(20)25(34)22(26(2,3)4)29-23(32)18-9-10-18/h5-8,14,18-20,22,31H,9-13H2,1-4H3,(H,27,33)(H,29,32)/t19-,20+,22-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459954 (CHEMBL4228950) Show SMILES CC(=O)C1(CC1)C(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| Show InChI InChI=1S/C28H36N4O5S/c1-16-22(38-15-30-16)19-8-6-18(7-9-19)13-29-24(35)21-12-20(34)14-32(21)25(36)23(27(3,4)5)31-26(37)28(10-11-28)17(2)33/h6-9,15,20-21,23,34H,10-14H2,1-5H3,(H,29,35)(H,31,37)/t20-,21+,23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50099062 (CHEMBL3344081 | US10730870, Example 3 | US11512083...) Show SMILES CC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| Show InChI InChI=1S/C24H32N4O4S/c1-14-20(33-13-26-14)17-8-6-16(7-9-17)11-25-22(31)19-10-18(30)12-28(19)23(32)21(24(3,4)5)27-15(2)29/h6-9,13,18-19,21,30H,10-12H2,1-5H3,(H,25,31)(H,27,29)/t18-,19+,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VHL (unknown origin)/elongin C (unknown origin)/elongin B (unknown origin) by isothermal titration calorimetry-based assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459960 (CHEMBL4225199) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C(Cl)(Cl)Cl)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C24H29Cl3N4O4S/c1-13-18(36-12-29-13)15-7-5-14(6-8-15)10-28-20(33)17-9-16(32)11-31(17)21(34)19(23(2,3)4)30-22(35)24(25,26)27/h5-8,12,16-17,19,32H,9-11H2,1-4H3,(H,28,33)(H,30,35)/t16-,17+,19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair
Elongin-C (Homo sapiens (Human))	BDBM50459947 (CHEMBL4225856) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CO)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C24H32N4O5S/c1-14-20(34-13-26-14)16-7-5-15(6-8-16)10-25-22(32)18-9-17(30)11-28(18)23(33)21(24(2,3)4)27-19(31)12-29/h5-8,13,17-18,21,29-30H,9-12H2,1-4H3,(H,25,32)(H,27,31)/t17-,18+,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459945 (CHEMBL4229211) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2CCC2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C27H36N4O4S/c1-16-22(36-15-29-16)18-10-8-17(9-11-18)13-28-25(34)21-12-20(32)14-31(21)26(35)23(27(2,3)4)30-24(33)19-6-5-7-19/h8-11,15,19-21,23,32H,5-7,12-14H2,1-4H3,(H,28,34)(H,30,33)/t20-,21+,23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VHL (unknown origin)/elongin C (unknown origin)/elongin B (unknown origin) by isothermal titration calorimetry-based assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459961 (CHEMBL4225714) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2COC2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C26H34N4O5S/c1-15-21(36-14-28-15)17-7-5-16(6-8-17)10-27-24(33)20-9-19(31)11-30(20)25(34)22(26(2,3)4)29-23(32)18-12-35-13-18/h5-8,14,18-20,22,31H,9-13H2,1-4H3,(H,27,33)(H,29,32)/t19-,20+,22-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VHL (unknown origin)/elongin C (unknown origin)/elongin B (unknown origin) by isothermal titration calorimetry-based assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459945 (CHEMBL4229211) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2CCC2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C27H36N4O4S/c1-16-22(36-15-29-16)18-10-8-17(9-11-18)13-28-25(34)21-12-20(32)14-31(21)26(35)23(27(2,3)4)30-24(33)19-6-5-7-19/h8-11,15,19-21,23,32H,5-7,12-14H2,1-4H3,(H,28,34)(H,30,33)/t20-,21+,23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	233	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VBC (unknown origin) at 50 uM at 20 degC by surface plasmon resonance assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459945 (CHEMBL4229211) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2CCC2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C27H36N4O4S/c1-16-22(36-15-29-16)18-10-8-17(9-11-18)13-28-25(34)21-12-20(32)14-31(21)26(35)23(27(2,3)4)30-24(33)19-6-5-7-19/h8-11,15,19-21,23,32H,5-7,12-14H2,1-4H3,(H,28,34)(H,30,33)/t20-,21+,23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459950 (CHEMBL4228963) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C(F)(F)F)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C24H29F3N4O4S/c1-13-18(36-12-29-13)15-7-5-14(6-8-15)10-28-20(33)17-9-16(32)11-31(17)21(34)19(23(2,3)4)30-22(35)24(25,26)27/h5-8,12,16-17,19,32H,9-11H2,1-4H3,(H,28,33)(H,30,35)/t16-,17+,19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair
Elongin-C (Homo sapiens (Human))	BDBM50459945 (CHEMBL4229211) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2CCC2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C27H36N4O4S/c1-16-22(36-15-29-16)18-10-8-17(9-11-18)13-28-25(34)21-12-20(32)14-31(21)26(35)23(27(2,3)4)30-24(33)19-6-5-7-19/h8-11,15,19-21,23,32H,5-7,12-14H2,1-4H3,(H,28,34)(H,30,33)/t20-,21+,23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	271	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VBC (unknown origin) at 50 uM at 10 degC by surface plasmon resonance assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459955 (CHEMBL4228624) Show SMILES CC(=O)NC1(CC1)C(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| Show InChI InChI=1S/C28H37N5O5S/c1-16-22(39-15-30-16)19-8-6-18(7-9-19)13-29-24(36)21-12-20(35)14-33(21)25(37)23(27(3,4)5)31-26(38)28(10-11-28)32-17(2)34/h6-9,15,20-21,23,35H,10-14H2,1-5H3,(H,29,36)(H,31,38)(H,32,34)/t20-,21+,23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459961 (CHEMBL4225714) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2COC2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C26H34N4O5S/c1-15-21(36-14-28-15)17-7-5-16(6-8-17)10-27-24(33)20-9-19(31)11-30(20)25(34)22(26(2,3)4)29-23(32)18-12-35-13-18/h5-8,14,18-20,22,31H,9-13H2,1-4H3,(H,27,33)(H,29,32)/t19-,20+,22-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459948 (CHEMBL4228328 | US10730870, Example 12 | US1151208...) Show SMILES CCC(=O)N[C@H](C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C)C(C)(C)C |r| Show InChI InChI=1S/C25H34N4O4S/c1-6-20(31)28-22(25(3,4)5)24(33)29-13-18(30)11-19(29)23(32)26-12-16-7-9-17(10-8-16)21-15(2)27-14-34-21/h7-10,14,18-19,22,30H,6,11-13H2,1-5H3,(H,26,32)(H,28,31)/t18-,19+,22-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair
Elongin-C (Homo sapiens (Human))	BDBM50459953 (CHEMBL4228692) Show SMILES C[C@@H](O)[C@H](NC(=O)C1(F)CC1)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C24H29FN4O5S/c1-13-20(35-12-27-13)16-5-3-15(4-6-16)10-26-21(32)18-9-17(31)11-29(18)22(33)19(14(2)30)28-23(34)24(25)7-8-24/h3-6,12,14,17-19,30-31H,7-11H2,1-2H3,(H,26,32)(H,28,34)/t14-,17-,18+,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair
Elongin-C (Homo sapiens (Human))	BDBM50459942 (CHEMBL4227864 | US10730870, Example 85 | US1151208...) Show SMILES C[C@H](NC(C)=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C21H26N4O4S/c1-12-19(30-11-23-12)16-6-4-15(5-7-16)9-22-20(28)18-8-17(27)10-25(18)21(29)13(2)24-14(3)26/h4-7,11,13,17-18,27H,8-10H2,1-3H3,(H,22,28)(H,24,26)/t13-,17+,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	440	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VBC complex (unknown origin) by ITC assay				Bioorg Med Chem 26: 2992-2995 (2018) Article DOI: 10.1016/j.bmc.2018.03.034 BindingDB Entry DOI: 10.7270/Q2HX1GB7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459959 (CHEMBL4225145) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CC(C)(C)C)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C28H40N4O4S/c1-17-23(37-16-30-17)19-10-8-18(9-11-19)14-29-25(35)21-12-20(33)15-32(21)26(36)24(28(5,6)7)31-22(34)13-27(2,3)4/h8-11,16,20-21,24,33H,12-15H2,1-7H3,(H,29,35)(H,31,34)/t20-,21+,24-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair
Elongin-C (Homo sapiens (Human))	BDBM50459956 (CHEMBL4224868) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C2CC(=O)C2)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C27H34N4O5S/c1-15-22(37-14-29-15)17-7-5-16(6-8-17)12-28-25(35)21-11-20(33)13-31(21)26(36)23(27(2,3)4)30-24(34)18-9-19(32)10-18/h5-8,14,18,20-21,23,33H,9-13H2,1-4H3,(H,28,35)(H,30,34)/t20-,21+,23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair
Elongin-C (Homo sapiens (Human))	BDBM50459942 (CHEMBL4227864 | US10730870, Example 85 | US1151208...) Show SMILES C[C@H](NC(C)=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C21H26N4O4S/c1-12-19(30-11-23-12)16-6-4-15(5-7-16)9-22-20(28)18-8-17(27)10-25(18)21(29)13(2)24-14(3)26/h4-7,11,13,17-18,27H,8-10H2,1-3H3,(H,22,28)(H,24,26)/t13-,17+,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	690	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VBC complex (unknown origin) assessed as reduction of FAM-labelled HIF1alpha peptide binding by fluorescence polarization assay				Bioorg Med Chem 26: 2992-2995 (2018) Article DOI: 10.1016/j.bmc.2018.03.034 BindingDB Entry DOI: 10.7270/Q2HX1GB7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50461569 (CHEMBL4228750) Show SMILES C[C@H](NC(C)=O)C(=S)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C21H26N4O3S2/c1-12-19(30-11-23-12)16-6-4-15(5-7-16)9-22-20(28)18-8-17(27)10-25(18)21(29)13(2)24-14(3)26/h4-7,11,13,17-18,27H,8-10H2,1-3H3,(H,22,28)(H,24,26)/t13-,17+,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VBC complex (unknown origin) by ITC assay				Bioorg Med Chem 26: 2992-2995 (2018) Article DOI: 10.1016/j.bmc.2018.03.034 BindingDB Entry DOI: 10.7270/Q2HX1GB7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459942 (CHEMBL4227864 | US10730870, Example 85 | US1151208...) Show SMILES C[C@H](NC(C)=O)C(=O)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C21H26N4O4S/c1-12-19(30-11-23-12)16-6-4-15(5-7-16)9-22-20(28)18-8-17(27)10-25(18)21(29)13(2)24-14(3)26/h4-7,11,13,17-18,27H,8-10H2,1-3H3,(H,22,28)(H,24,26)/t13-,17+,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459951 (CHEMBL4229225) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)C(C)(C)F)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C26H35FN4O4S/c1-15-20(36-14-29-15)17-9-7-16(8-10-17)12-28-22(33)19-11-18(32)13-31(19)23(34)21(25(2,3)4)30-24(35)26(5,6)27/h7-10,14,18-19,21,32H,11-13H2,1-6H3,(H,28,33)(H,30,35)/t18-,19+,21-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	770	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair
Elongin-C (Homo sapiens (Human))	BDBM50461569 (CHEMBL4228750) Show SMILES C[C@H](NC(C)=O)C(=S)N1C[C@H](O)C[C@H]1C(=O)NCc1ccc(cc1)-c1scnc1C |r| Show InChI InChI=1S/C21H26N4O3S2/c1-12-19(30-11-23-12)16-6-4-15(5-7-16)9-22-20(28)18-8-17(27)10-25(18)21(29)13(2)24-14(3)26/h4-7,11,13,17-18,27H,8-10H2,1-3H3,(H,22,28)(H,24,26)/t13-,17+,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Binding affinity to VBC complex (unknown origin) assessed as reduction of FAM-labelled HIF1alpha peptide binding by fluorescence polarization assay				Bioorg Med Chem 26: 2992-2995 (2018) Article DOI: 10.1016/j.bmc.2018.03.034 BindingDB Entry DOI: 10.7270/Q2HX1GB7
					More data for this Ligand-Target Pair				3D Structure (crystal)
Elongin-C (Homo sapiens (Human))	BDBM50459957 (CHEMBL4229276) Show SMILES Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](N2CCCC2=O)C(C)(C)C)cc1 |r| Show InChI InChI=1S/C26H34N4O4S/c1-16-22(35-15-28-16)18-9-7-17(8-10-18)13-27-24(33)20-12-19(31)14-30(20)25(34)23(26(2,3)4)29-11-5-6-21(29)32/h7-10,15,19-20,23,31H,5-6,11-14H2,1-4H3,(H,27,33)/t19-,20+,23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a
University of Dundee Curated by ChEMBL					Assay Description Displacement of FAM-labeled HIF-1alpha peptide from VBC (unknown origin) by fluorescence polarization assay				J Med Chem 61: 599-618 (2018) Article DOI: 10.1021/acs.jmedchem.7b00675 BindingDB Entry DOI: 10.7270/Q2736TJ6
					More data for this Ligand-Target Pair

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