Compile Data Set for Download or QSAR

Found 13 hits of ki data for polymerid = 50006629   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2cn(C)c3ccccc23)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-8-17(9-5-2)22(27)29-16-24(15-26)13-18(23(28)30-24)12-19-14-25(3)21-11-7-6-10-20(19)21/h6-7,10-12,14,17,26H,4-5,8-9,13,15-16H2,1-3H3/b18-12+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50017890 (CHEMBL3289012) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc3n(C)ccc3c2)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-6-18(7-5-2)22(27)29-16-24(15-26)14-20(23(28)30-24)13-17-8-9-21-19(12-17)10-11-25(21)3/h8-13,18,26H,4-7,14-16H2,1-3H3/b20-13+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.410	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50244449 ((E)-(2-(hydroxymethyl)-4-((1-methyl-1H-indol-3-yl)...) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2cn(C)c3ccccc23)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-8-17(9-5-2)22(27)29-16-24(15-26)13-18(23(28)30-24)12-19-14-25(3)21-11-7-6-10-20(19)21/h6-7,10-12,14,17,26H,4-5,8-9,13,15-16H2,1-3H3/b18-12+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from RasGRP1 (unknown origin) in the presence of porcine brain phosphatidylserine by scintillation co...				Bioorg Med Chem 25: 2971-2980 (2017) Article DOI: 10.1016/j.bmc.2017.03.022 BindingDB Entry DOI: 10.7270/Q28P62P2
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50017892 (CHEMBL3289014) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2cccc3ccn(C)c23)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-7-18(8-5-2)22(27)29-16-24(15-26)14-20(23(28)30-24)13-19-10-6-9-17-11-12-25(3)21(17)19/h6,9-13,18,26H,4-5,7-8,14-16H2,1-3H3/b20-13+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50017891 (CHEMBL3289013) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2ccc3ccn(C)c3c2)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-6-19(7-5-2)22(27)29-16-24(15-26)14-20(23(28)30-24)12-17-8-9-18-10-11-25(3)21(18)13-17/h8-13,19,26H,4-7,14-16H2,1-3H3/b20-12+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50017889 (CHEMBL3289011) Show SMILES CCCC(CCC)C(=O)OCC1(CO)C\C(=C/c2cccc3n(C)ccc23)C(=O)O1 Show InChI InChI=1S/C24H31NO5/c1-4-7-17(8-5-2)22(27)29-16-24(15-26)14-19(23(28)30-24)13-18-9-6-10-21-20(18)11-12-25(21)3/h6,9-13,17,26H,4-5,7-8,14-16H2,1-3H3/b19-13+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [3H]PDBu from recombinant RasGRP1 C1 domain (unknown origin) after 10 mins by scintillation counting analysis in presence of phosphat...				Bioorg Med Chem 22: 3123-40 (2014) Article DOI: 10.1016/j.bmc.2014.04.024 BindingDB Entry DOI: 10.7270/Q2P270QK
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50241849 (CHEMBL4070999) Show SMILES CC(C)C(C\C=C1\CC(CO)(COC(=O)c2cn(C)c3ccccc23)OC1=O)C(C)C Show InChI InChI=1S/C25H33NO5/c1-16(2)19(17(3)4)11-10-18-12-25(14-27,31-23(18)28)15-30-24(29)21-13-26(5)22-9-7-6-8-20(21)22/h6-10,13,16-17,19,27H,11-12,14-15H2,1-5H3/b18-10-	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from RasGRP1 (unknown origin) in the presence of porcine brain phosphatidylserine by scintillation co...				Bioorg Med Chem 25: 2971-2980 (2017) Article DOI: 10.1016/j.bmc.2017.03.022 BindingDB Entry DOI: 10.7270/Q28P62P2
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50241856 (CHEMBL4097154) Show SMILES Cc1ccc(cc1)C#Cc1ccc(C=C2CC(CO)(COC(=O)c3cn(C)c4ccccc34)OC2=O)cc1 Show InChI InChI=1S/C32H27NO5/c1-22-7-9-23(10-8-22)11-12-24-13-15-25(16-14-24)17-26-18-32(20-34,38-30(26)35)21-37-31(36)28-19-33(2)29-6-4-3-5-27(28)29/h3-10,13-17,19,34H,18,20-21H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from RasGRP1 (unknown origin) in the presence of porcine brain phosphatidylserine by scintillation co...				Bioorg Med Chem 25: 2971-2980 (2017) Article DOI: 10.1016/j.bmc.2017.03.022 BindingDB Entry DOI: 10.7270/Q28P62P2
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50241855 (CHEMBL4075373) Show SMILES CC(C)C(C\C=C1/CC(CO)(COC(=O)c2cn(C)c3ccccc23)OC1=O)C(C)C Show InChI InChI=1S/C25H33NO5/c1-16(2)19(17(3)4)11-10-18-12-25(14-27,31-23(18)28)15-30-24(29)21-13-26(5)22-9-7-6-8-20(21)22/h6-10,13,16-17,19,27H,11-12,14-15H2,1-5H3/b18-10+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from RasGRP1 (unknown origin) in the presence of porcine brain phosphatidylserine by scintillation co...				Bioorg Med Chem 25: 2971-2980 (2017) Article DOI: 10.1016/j.bmc.2017.03.022 BindingDB Entry DOI: 10.7270/Q28P62P2
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50241846 (CHEMBL4069954) Show SMILES Cc1ccc(cc1)C#Cc1ccc(\C=C2/CC(CO)(COC(=O)c3cn(C)c4ccccc34)OC2=O)cc1 Show InChI InChI=1S/C32H27NO5/c1-22-7-9-23(10-8-22)11-12-24-13-15-25(16-14-24)17-26-18-32(20-34,38-30(26)35)21-37-31(36)28-19-33(2)29-6-4-3-5-27(28)29/h3-10,13-17,19,34H,18,20-21H2,1-2H3/b26-17+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from RasGRP1 (unknown origin) in the presence of porcine brain phosphatidylserine by scintillation co...				Bioorg Med Chem 25: 2971-2980 (2017) Article DOI: 10.1016/j.bmc.2017.03.022 BindingDB Entry DOI: 10.7270/Q28P62P2
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50241851 (CHEMBL4099579) Show SMILES CCCCCCCCC\C=C1/CC(CO)(COC(=O)c2cn(C)c3ccccc23)OC1=O Show InChI InChI=1S/C26H35NO5/c1-3-4-5-6-7-8-9-10-13-20-16-26(18-28,32-24(20)29)19-31-25(30)22-17-27(2)23-15-12-11-14-21(22)23/h11-15,17,28H,3-10,16,18-19H2,1-2H3/b20-13+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from RasGRP1 (unknown origin) in the presence of porcine brain phosphatidylserine by scintillation co...				Bioorg Med Chem 25: 2971-2980 (2017) Article DOI: 10.1016/j.bmc.2017.03.022 BindingDB Entry DOI: 10.7270/Q28P62P2
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50241850 (CHEMBL4081576) Show SMILES CCCC(CCC)\C=C1/CC(CO)(COC(=O)c2cn(C)c3ccccc23)OC1=O Show InChI InChI=1S/C24H31NO5/c1-4-8-17(9-5-2)12-18-13-24(15-26,30-22(18)27)16-29-23(28)20-14-25(3)21-11-7-6-10-19(20)21/h6-7,10-12,14,17,26H,4-5,8-9,13,15-16H2,1-3H3/b18-12+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	133	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from RasGRP1 (unknown origin) in the presence of porcine brain phosphatidylserine by scintillation co...				Bioorg Med Chem 25: 2971-2980 (2017) Article DOI: 10.1016/j.bmc.2017.03.022 BindingDB Entry DOI: 10.7270/Q28P62P2
					More data for this Ligand-Target Pair
RAS guanyl-releasing protein 1 (Homo sapiens (Human))	BDBM50241854 (CHEMBL4066764) Show SMILES [#6]\[#6](-[#6])=[#6]-1/[#6]C([#6]-[#8])([#6]-[#8]-[#6](=O)-c2cn(-[#6])c3ccccc23)[#8]-[#6]-1=O Show InChI InChI=1S/C19H21NO5/c1-12(2)14-8-19(10-21,25-18(14)23)11-24-17(22)15-9-20(3)16-7-5-4-6-13(15)16/h4-7,9,21H,8,10-11H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	666	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Industrial Technology Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from RasGRP1 (unknown origin) in the presence of porcine brain phosphatidylserine by scintillation co...				Bioorg Med Chem 25: 2971-2980 (2017) Article DOI: 10.1016/j.bmc.2017.03.022 BindingDB Entry DOI: 10.7270/Q28P62P2
					More data for this Ligand-Target Pair