Compile Data Set for Download or QSAR

Found 68 hits of ic50 data for polymerid = 50006687   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072265 (CHEMBL3408320) Show SMILES CCn1c2ccc(cc2n(CC)c1=O)C(=O)c1cnn(C)c1O Show InChI InChI=1S/C16H18N4O3/c1-4-19-12-7-6-10(8-13(12)20(5-2)16(19)23)14(21)11-9-17-18(3)15(11)22/h6-9,22H,4-5H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072264 (CHEMBL3408319) Show SMILES CCCn1c2cc(ccc2n(CC)c1=O)C(=O)c1cnn(C)c1O Show InChI InChI=1S/C17H20N4O3/c1-4-8-21-14-9-11(6-7-13(14)20(5-2)17(21)24)15(22)12-10-18-19(3)16(12)23/h6-7,9-10,23H,4-5,8H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072237 (CHEMBL3408314) Show SMILES CCn1c2cc(ccc2n(C)c1=O)C(=O)c1cnn(C)c1O Show InChI InChI=1S/C15H16N4O3/c1-4-19-12-7-9(5-6-11(12)17(2)15(19)22)13(20)10-8-16-18(3)14(10)21/h5-8,21H,4H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072269 (CHEMBL3408324) Show SMILES CCCn1c2ccc(cc2n(CC)c1=O)C(=O)c1cnn(C)c1O Show InChI InChI=1S/C17H20N4O3/c1-4-8-21-13-7-6-11(9-14(13)20(5-2)17(21)24)15(22)12-10-18-19(3)16(12)23/h6-7,9-10,23H,4-5,8H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072270 (CHEMBL3408325) Show SMILES CCCn1c2ccc(cc2n(CCC)c1=O)C(=O)c1cnn(C)c1O Show InChI InChI=1S/C18H22N4O3/c1-4-8-21-14-7-6-12(10-15(14)22(9-5-2)18(21)25)16(23)13-11-19-20(3)17(13)24/h6-7,10-11,24H,4-5,8-9H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536974 (CHEMBL4533679) Show SMILES OC1=C(C(=O)c2cccc(OCc3ccc(Br)cc3)c2[N+]([O-])=O)C(=O)CCC1 |c:1| Show InChI InChI=1S/C20H16BrNO6/c21-13-9-7-12(8-10-13)11-28-17-6-1-3-14(19(17)22(26)27)20(25)18-15(23)4-2-5-16(18)24/h1,3,6-10,23H,2,4-5,11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072230 (CHEMBL3408157) Show SMILES CCCn1c2cc(ccc2n(C)c1=O)C(=O)c1cnn(C)c1O Show InChI InChI=1S/C16H18N4O3/c1-4-7-20-13-8-10(5-6-12(13)18(2)16(20)23)14(21)11-9-17-19(3)15(11)22/h5-6,8-9,22H,4,7H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072236 (CHEMBL3408313) Show SMILES CC(C)n1c2cc(ccc2n(C)c1=O)C(=O)c1cnn(C)c1O Show InChI InChI=1S/C16H18N4O3/c1-9(2)20-13-7-10(5-6-12(13)18(3)16(20)23)14(21)11-8-17-19(4)15(11)22/h5-9,22H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536949 (CHEMBL4526579) Show SMILES OC1=C(C(=O)c2cccc(OCc3ccc(Cl)cc3Cl)c2[N+]([O-])=O)C(=O)CCC1 |c:1| Show InChI InChI=1S/C20H15Cl2NO6/c21-12-8-7-11(14(22)9-12)10-29-17-6-1-3-13(19(17)23(27)28)20(26)18-15(24)4-2-5-16(18)25/h1,3,6-9,24H,2,4-5,10H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072266 (CHEMBL3408321) Show SMILES CCn1c2ccc(cc2n(C(C)C)c1=O)C(=O)c1cnn(C)c1O Show InChI InChI=1S/C17H20N4O3/c1-5-20-13-7-6-11(8-14(13)21(10(2)3)17(20)24)15(22)12-9-18-19(4)16(12)23/h6-10,23H,5H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536950 (CHEMBL4564855) Show SMILES OC1=C(C(=O)c2cccc(OCc3ccc(Br)cc3F)c2[N+]([O-])=O)C(=O)CCC1 |c:1| Show InChI InChI=1S/C20H15BrFNO6/c21-12-8-7-11(14(22)9-12)10-29-17-6-1-3-13(19(17)23(27)28)20(26)18-15(24)4-2-5-16(18)25/h1,3,6-9,24H,2,4-5,10H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536973 (CHEMBL4582009) Show SMILES Cc1cc(C)cc(COc2cccc(C(=O)C3=C(O)CCCC3=O)c2[N+]([O-])=O)c1 |c:16| Show InChI InChI=1S/C22H21NO6/c1-13-9-14(2)11-15(10-13)12-29-19-8-3-5-16(21(19)23(27)28)22(26)20-17(24)6-4-7-18(20)25/h3,5,8-11,24H,4,6-7,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072223 (CHEMBL3408156) Show SMILES CCC(=O)C(C(C)=O)C(=O)c1ccc(cc1[N+]([O-])=O)C(F)(F)F Show InChI InChI=1S/C14H12F3NO5/c1-3-11(20)12(7(2)19)13(21)9-5-4-8(14(15,16)17)6-10(9)18(22)23/h4-6,12H,3H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536952 (CHEMBL4571726) Show SMILES CC(C)c1ccc(COc2cccc(C(=O)C3=C(O)CCCC3=O)c2[N+]([O-])=O)cc1 |c:16| Show InChI InChI=1S/C23H23NO6/c1-14(2)16-11-9-15(10-12-16)13-30-20-8-3-5-17(22(20)24(28)29)23(27)21-18(25)6-4-7-19(21)26/h3,5,8-12,14,25H,4,6-7,13H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536946 (CHEMBL4540372) Show SMILES Cc1ccc(COc2cccc(C(=O)C3=C(O)CCCC3=O)c2[N+]([O-])=O)cc1 |c:14| Show InChI InChI=1S/C21H19NO6/c1-13-8-10-14(11-9-13)12-28-18-7-2-4-15(20(18)22(26)27)21(25)19-16(23)5-3-6-17(19)24/h2,4,7-11,23H,3,5-6,12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072271 (CHEMBL3408326) Show SMILES CCCn1c2ccc(cc2n(c1=O)C(C)(C)C)C(=O)c1cnn(C)c1O Show InChI InChI=1S/C19H24N4O3/c1-6-9-22-14-8-7-12(16(24)13-11-20-21(5)17(13)25)10-15(14)23(18(22)26)19(2,3)4/h7-8,10-11,25H,6,9H2,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536967 (CHEMBL4567229) Show SMILES OC1=C(C(=O)c2ccc(cc2[N+]([O-])=O)C(F)(F)F)C(=O)CCC1 |c:1| Show InChI InChI=1S/C14H10F3NO5/c15-14(16,17)7-4-5-8(9(6-7)18(22)23)13(21)12-10(19)2-1-3-11(12)20/h4-6,19H,1-3H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	85	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536966 (CHEMBL4554387) Show SMILES OC1=C(C(=O)c2cccc(OCc3ccc(Br)cc3)c2)C(=O)CCC1 |c:1| Show InChI InChI=1S/C20H17BrO4/c21-15-9-7-13(8-10-15)12-25-16-4-1-3-14(11-16)20(24)19-17(22)5-2-6-18(19)23/h1,3-4,7-11,22H,2,5-6,12H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536972 (CHEMBL4564283) Show SMILES OC1=C(C(=O)c2cccc(OCc3ccc(F)cc3F)c2[N+]([O-])=O)C(=O)CCC1 |c:1| Show InChI InChI=1S/C20H15F2NO6/c21-12-8-7-11(14(22)9-12)10-29-17-6-1-3-13(19(17)23(27)28)20(26)18-15(24)4-2-5-16(18)25/h1,3,6-9,24H,2,4-5,10H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072238 (CHEMBL3408315) Show SMILES Cn1ncc(C(=O)c2ccc3n(C)c(=O)n(c3c2)C(C)(C)C)c1O Show InChI InChI=1S/C17H20N4O3/c1-17(2,3)21-13-8-10(6-7-12(13)19(4)16(21)24)14(22)11-9-18-20(5)15(11)23/h6-9,23H,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072263 (CHEMBL3408318) Show SMILES Cn1ncc(C(=O)c2ccc3n(C)c(=O)n(C4CC4)c3c2)c1O Show InChI InChI=1S/C16H16N4O3/c1-18-12-6-3-9(14(21)11-8-17-19(2)15(11)22)7-13(12)20(16(18)23)10-4-5-10/h3,6-8,10,22H,4-5H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536954 (CHEMBL4574113) Show SMILES Cc1c(OCc2ccc(F)cc2)c(Cl)ccc1C(=O)C1=C(O)CCCC1=O |c:21| Show InChI InChI=1S/C21H18ClFO4/c1-12-15(20(26)19-17(24)3-2-4-18(19)25)9-10-16(22)21(12)27-11-13-5-7-14(23)8-6-13/h5-10,24H,2-4,11H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536968 (CHEMBL4539445) Show SMILES CC1CC(O)=C(C(=O)c2cccc(OCc3ccc(Br)cc3F)c2[N+]([O-])=O)C(=O)C1 |t:4| Show InChI InChI=1S/C21H17BrFNO6/c1-11-7-16(25)19(17(26)8-11)21(27)14-3-2-4-18(20(14)24(28)29)30-10-12-5-6-13(22)9-15(12)23/h2-6,9,11,25H,7-8,10H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536945 (CHEMBL4565020) Show SMILES CC1CC(O)=C(C(=O)c2cccc(OCc3ccc(Cl)cc3Cl)c2[N+]([O-])=O)C(=O)C1 |t:4| Show InChI InChI=1S/C21H17Cl2NO6/c1-11-7-16(25)19(17(26)8-11)21(27)14-3-2-4-18(20(14)24(28)29)30-10-12-5-6-13(22)9-15(12)23/h2-6,9,11,25H,7-8,10H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536962 (CHEMBL4571011) Show SMILES OC1=C(C(=O)c2cccc(OCc3ccc(Br)cc3F)c2)C(=O)CCC1 |c:1| Show InChI InChI=1S/C20H16BrFO4/c21-14-8-7-13(16(22)10-14)11-26-15-4-1-3-12(9-15)20(25)19-17(23)5-2-6-18(19)24/h1,3-4,7-10,23H,2,5-6,11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	121	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536953 (CHEMBL4577367) Show SMILES OC1=C(C(=O)c2cccc(OCc3ccc(F)cc3)c2[N+]([O-])=O)C(=O)CCC1 |c:1| Show InChI InChI=1S/C20H16FNO6/c21-13-9-7-12(8-10-13)11-28-17-6-1-3-14(19(17)22(26)27)20(25)18-15(23)4-2-5-16(18)24/h1,3,6-10,23H,2,4-5,11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536955 (CHEMBL4589830) Show SMILES Cc1c(ccc(Cl)c1OCc1ccccc1)C(=O)C1=C(O)CCCC1=O |c:20| Show InChI InChI=1S/C21H19ClO4/c1-13-15(20(25)19-17(23)8-5-9-18(19)24)10-11-16(22)21(13)26-12-14-6-3-2-4-7-14/h2-4,6-7,10-11,23H,5,8-9,12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	128	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072235 (CHEMBL3408312) Show SMILES Cn1ncc(C(=O)c2ccc3n(C)c(=O)n(C4CCCC4)c3c2)c1O Show InChI InChI=1S/C18H20N4O3/c1-20-14-8-7-11(16(23)13-10-19-21(2)17(13)24)9-15(14)22(18(20)25)12-5-3-4-6-12/h7-10,12,24H,3-6H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072240 (CHEMBL3408317) Show SMILES Cn1ncc(C(=O)c2ccc3n(C)c(=O)n(Cc4ccccc4)c3c2)c1O Show InChI InChI=1S/C20H18N4O3/c1-22-16-9-8-14(18(25)15-11-21-23(2)19(15)26)10-17(16)24(20(22)27)12-13-6-4-3-5-7-13/h3-11,26H,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072232 (CHEMBL3408311) Show SMILES CC(C)Cn1c2cc(ccc2n(C)c1=O)C(=O)c1cnn(C)c1O Show InChI InChI=1S/C17H20N4O3/c1-10(2)9-21-14-7-11(5-6-13(14)19(3)17(21)24)15(22)12-8-18-20(4)16(12)23/h5-8,10,23H,9H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536970 (CHEMBL4537208) Show SMILES OC1=C(C(=O)c2cccc(OCc3ccc(Cl)cc3Cl)c2)C(=O)CCC1 |c:1| Show InChI InChI=1S/C20H16Cl2O4/c21-14-8-7-13(16(22)10-14)11-26-15-4-1-3-12(9-15)20(25)19-17(23)5-2-6-18(19)24/h1,3-4,7-10,23H,2,5-6,11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536977 (CHEMBL4549115) Show SMILES OC1=C(C(=O)c2cccc(OCc3ccc(Cl)cc3F)c2)C(=O)CCC1 |c:1| Show InChI InChI=1S/C20H16ClFO4/c21-14-8-7-13(16(22)10-14)11-26-15-4-1-3-12(9-15)20(25)19-17(23)5-2-6-18(19)24/h1,3-4,7-10,23H,2,5-6,11H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072267 (CHEMBL3408322) Show SMILES CCn1c2ccc(cc2n(c1=O)C(C)(C)C)C(=O)c1cnn(C)c1O Show InChI InChI=1S/C18H22N4O3/c1-6-21-13-8-7-11(15(23)12-10-19-20(5)16(12)24)9-14(13)22(17(21)25)18(2,3)4/h7-10,24H,6H2,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536951 (CHEMBL4564075) Show SMILES CC1CC(O)=C(C(=O)c2cccc(OCc3ccc(C)cc3)c2[N+]([O-])=O)C(=O)C1 |t:4| Show InChI InChI=1S/C22H21NO6/c1-13-6-8-15(9-7-13)12-29-19-5-3-4-16(21(19)23(27)28)22(26)20-17(24)10-14(2)11-18(20)25/h3-9,14,24H,10-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	168	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072231 (CHEMBL3408310) Show SMILES CCCCn1c2cc(ccc2n(C)c1=O)C(=O)c1cnn(C)c1O Show InChI InChI=1S/C17H20N4O3/c1-4-5-8-21-14-9-11(6-7-13(14)19(2)17(21)24)15(22)12-10-18-20(3)16(12)23/h6-7,9-10,23H,4-5,8H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536959 (CHEMBL4582680) Show SMILES CC1CC(O)=C(C(=O)c2cccc(OCc3ccc(Br)cc3)c2)C(=O)C1 |t:4| Show InChI InChI=1S/C21H19BrO4/c1-13-9-18(23)20(19(24)10-13)21(25)15-3-2-4-17(11-15)26-12-14-5-7-16(22)8-6-14/h2-8,11,13,23H,9-10,12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	176	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536961 (CHEMBL4538931) Show SMILES CC1CC(O)=C(C(=O)c2cccc(OCc3ccc(Br)cc3F)c2)C(=O)C1 |t:4| Show InChI InChI=1S/C21H18BrFO4/c1-12-7-18(24)20(19(25)8-12)21(26)13-3-2-4-16(9-13)27-11-14-5-6-15(22)10-17(14)23/h2-6,9-10,12,24H,7-8,11H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536965 (CHEMBL4539505) Show SMILES OC1=C(C(=O)c2cccc(OCc3ccc(Cl)cc3)c2)C(=O)CCC1 |c:1| Show InChI InChI=1S/C20H17ClO4/c21-15-9-7-13(8-10-15)12-25-16-4-1-3-14(11-16)20(24)19-17(22)5-2-6-18(19)23/h1,3-4,7-11,22H,2,5-6,12H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	217	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072268 (CHEMBL3408323) Show SMILES CCn1c2ccc(cc2n(C2CC2)c1=O)C(=O)c1cnn(C)c1O Show InChI InChI=1S/C17H18N4O3/c1-3-20-13-7-4-10(15(22)12-9-18-19(2)16(12)23)8-14(13)21(17(20)24)11-5-6-11/h4,7-9,11,23H,3,5-6H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50072239 (CHEMBL3408316) Show SMILES Cc1ccc(cc1)-n1c2cc(ccc2n(C)c1=O)C(=O)c1cnn(C)c1O Show InChI InChI=1S/C20H18N4O3/c1-12-4-7-14(8-5-12)24-17-10-13(6-9-16(17)22(2)20(24)27)18(25)15-11-21-23(3)19(15)26/h4-11,26H,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant His-tagged HPPD expressed in Escherichia coli BL21(DE3) by UV/visible plate reader analysis				Eur J Med Chem 92: 427-38 (2015) Article DOI: 10.1016/j.ejmech.2015.01.018 BindingDB Entry DOI: 10.7270/Q20C4XFX
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536969 (CHEMBL4541040) Show SMILES Cc1c(OCc2ccc(Cl)cc2F)cccc1C(=O)C1=C(O)CCCC1=O |c:21| Show InChI InChI=1S/C21H18ClFO4/c1-12-15(21(26)20-17(24)5-3-6-18(20)25)4-2-7-19(12)27-11-13-8-9-14(22)10-16(13)23/h2,4,7-10,24H,3,5-6,11H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	257	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536978 (CHEMBL4591004) Show SMILES OC1=C(C(=O)c2cccc(OCc3ccc(F)cc3)c2)C(=O)CCC1 |c:1| Show InChI InChI=1S/C20H17FO4/c21-15-9-7-13(8-10-15)12-25-16-4-1-3-14(11-16)20(24)19-17(22)5-2-6-18(19)23/h1,3-4,7-11,22H,2,5-6,12H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	264	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536947 (CHEMBL4529209) Show SMILES Cc1c(OCc2ccc(Cl)cc2)cccc1C(=O)C1=C(O)CCCC1=O |c:20| Show InChI InChI=1S/C21H19ClO4/c1-13-16(21(25)20-17(23)5-3-6-18(20)24)4-2-7-19(13)26-12-14-8-10-15(22)11-9-14/h2,4,7-11,23H,3,5-6,12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	266	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536948 (CHEMBL4521608) Show SMILES Cc1ccc(COc2cccc(c2)C(=O)C2=C(O)CCCC2=O)cc1 |c:16| Show InChI InChI=1S/C21H20O4/c1-14-8-10-15(11-9-14)13-25-17-5-2-4-16(12-17)21(24)20-18(22)6-3-7-19(20)23/h2,4-5,8-12,22H,3,6-7,13H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	266	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536964 (CHEMBL4561368) Show SMILES OC1=C(C(=O)c2cccc(OCc3cccc(F)c3)c2)C(=O)CCC1 |c:1| Show InChI InChI=1S/C20H17FO4/c21-15-6-1-4-13(10-15)12-25-16-7-2-5-14(11-16)20(24)19-17(22)8-3-9-18(19)23/h1-2,4-7,10-11,22H,3,8-9,12H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	274	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536976 (CHEMBL4518798) Show SMILES Cc1c(OCc2ccc(Br)cc2)cccc1C(=O)C1=C(O)CCCC1=O |c:20| Show InChI InChI=1S/C21H19BrO4/c1-13-16(21(25)20-17(23)5-3-6-18(20)24)4-2-7-19(13)26-12-14-8-10-15(22)11-9-14/h2,4,7-11,23H,3,5-6,12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	274	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536975 (CHEMBL4519334) Show SMILES Cc1c(OCc2cccc(Br)c2)cccc1C(=O)C1=C(O)CCCC1=O |c:20| Show InChI InChI=1S/C21H19BrO4/c1-13-16(21(25)20-17(23)8-4-9-18(20)24)7-3-10-19(13)26-12-14-5-2-6-15(22)11-14/h2-3,5-7,10-11,23H,4,8-9,12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536957 (CHEMBL4552681) Show SMILES Cc1c(OCc2ccc(F)cc2)cccc1C(=O)C1=C(O)CCCC1=O |c:20| Show InChI InChI=1S/C21H19FO4/c1-13-16(21(25)20-17(23)5-3-6-18(20)24)4-2-7-19(13)26-12-14-8-10-15(22)11-9-14/h2,4,7-11,23H,3,5-6,12H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	302	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536971 (CHEMBL4547046) Show SMILES OC1=C(C(=O)c2cccc(OCc3ccccc3)c2)C(=O)CCC1 |c:1| Show InChI InChI=1S/C20H18O4/c21-17-10-5-11-18(22)19(17)20(23)15-8-4-9-16(12-15)24-13-14-6-2-1-3-7-14/h1-4,6-9,12,21H,5,10-11,13H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	335	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair
4-hydroxyphenylpyruvate dioxygenase (Homo sapiens (Human))	BDBM50536958 (CHEMBL4533367) Show SMILES Cc1ccc(COc2cccc(C(=O)C3=C(O)CCCC3=O)c2C)cc1 |c:14| Show InChI InChI=1S/C22H22O4/c1-14-9-11-16(12-10-14)13-26-20-8-3-5-17(15(20)2)22(25)21-18(23)6-4-7-19(21)24/h3,5,8-12,23H,4,6-7,13H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	374	n/a	n/a	n/a	n/a	n/a	n/a
Central China Normal University Curated by ChEMBL					Assay Description Inhibition of human recombinant HPPD expressed in Escherichia coli BL21 (DE3) assessed as effect on maleylacetoacetate formation incubated for 10 min...				Eur J Med Chem 166: 22-31 (2019) Article DOI: 10.1016/j.ejmech.2019.01.032 BindingDB Entry DOI: 10.7270/Q2T72MZ7
					More data for this Ligand-Target Pair

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