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Compile Data Set for Download or QSAR

Found 90 hits of ic50 data for polymerid = 50006820   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069751
PNG
(CHEMBL2356114)
Show SMILES C[C@@H](N(C1CCCCC1)C(=O)Cn1nnc(n1)-c1ccc2OCOc2c1)C(=O)NC1CCCC1
Show InChI InChI=1S/C24H32N6O4/c1-16(24(32)25-18-7-5-6-8-18)30(19-9-3-2-4-10-19)22(31)14-29-27-23(26-28-29)17-11-12-20-21(13-17)34-15-33-20/h11-13,16,18-19H,2-10,14-15H2,1H3,(H,25,32)/t16-/m1/s1
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n/an/a 5n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in uptake of [3H]CE from [3H]CE-HDL by by liquid scintillation count...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069751
PNG
(CHEMBL2356114)
Show SMILES C[C@@H](N(C1CCCCC1)C(=O)Cn1nnc(n1)-c1ccc2OCOc2c1)C(=O)NC1CCCC1
Show InChI InChI=1S/C24H32N6O4/c1-16(24(32)25-18-7-5-6-8-18)30(19-9-3-2-4-10-19)22(31)14-29-27-23(26-28-29)17-11-12-20-21(13-17)34-15-33-20/h11-13,16,18-19H,2-10,14-15H2,1H3,(H,25,32)/t16-/m1/s1
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n/an/a 5n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of [3H]cholesteryl ester uptake into cells after 2 to 3 hrs by liquid sci...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069751
PNG
(CHEMBL2356114)
Show SMILES C[C@@H](N(C1CCCCC1)C(=O)Cn1nnc(n1)-c1ccc2OCOc2c1)C(=O)NC1CCCC1
Show InChI InChI=1S/C24H32N6O4/c1-16(24(32)25-18-7-5-6-8-18)30(19-9-3-2-4-10-19)22(31)14-29-27-23(26-28-29)17-11-12-20-21(13-17)34-15-33-20/h11-13,16,18-19H,2-10,14-15H2,1H3,(H,25,32)/t16-/m1/s1
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n/an/a 17n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088281
PNG
(CHEMBL3427475)
Show SMILES COc1ccc(cc1OC)-c1cc(CC(=O)N(C(C)C(=O)NC2CCCC2)C2CCCCC2)no1
Show InChI InChI=1S/C27H37N3O5/c1-18(27(32)28-20-9-7-8-10-20)30(22-11-5-4-6-12-22)26(31)17-21-16-24(35-29-21)19-13-14-23(33-2)25(15-19)34-3/h13-16,18,20,22H,4-12,17H2,1-3H3,(H,28,32)
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n/an/a 23n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088195
PNG
(CHEMBL3427497)
Show SMILES O=C(CN(C1CCCCC1)C(=O)Cn1nnc(n1)-c1ccc2OCOc2c1)NC1CCCC1
Show InChI InChI=1S/C23H30N6O4/c30-21(24-17-6-4-5-7-17)13-28(18-8-2-1-3-9-18)22(31)14-29-26-23(25-27-29)16-10-11-19-20(12-16)33-15-32-19/h10-12,17-18H,1-9,13-15H2,(H,24,30)
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n/an/a 26n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088267
PNG
(CHEMBL3427489)
Show SMILES CC(N(C1CCCCC1)C(=O)Cn1nnc(n1)-c1ccc2OCOc2c1)C(=O)NC1CCCC1
Show InChI InChI=1S/C24H32N6O4/c1-16(24(32)25-18-7-5-6-8-18)30(19-9-3-2-4-10-19)22(31)14-29-27-23(26-28-29)17-11-12-20-21(13-17)34-15-33-20/h11-13,16,18-19H,2-10,14-15H2,1H3,(H,25,32)
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n/an/a 27n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069719
PNG
(CHEMBL2358771)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)C3CCCCC3)cc2C1=O
Show InChI InChI=1S/C29H38ClN3O6S/c1-19-16-33(20(2)18-34)29(36)25-15-23(31-28(35)21-7-5-4-6-8-21)11-14-26(25)39-27(19)17-32(3)40(37,38)24-12-9-22(30)10-13-24/h9-15,19-21,27,34H,4-8,16-18H2,1-3H3,(H,31,35)/t19-,20-,27+/m1/s1
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n/an/a 54n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088283
PNG
(CHEMBL1478888)
Show SMILES COc1ccc(cc1OC)-c1nnn(CC(=O)N(C(C)C(=O)NC2CCCC2)C2CCCCC2)n1
Show InChI InChI=1S/C25H36N6O4/c1-17(25(33)26-19-9-7-8-10-19)31(20-11-5-4-6-12-20)23(32)16-30-28-24(27-29-30)18-13-14-21(34-2)22(15-18)35-3/h13-15,17,19-20H,4-12,16H2,1-3H3,(H,26,33)
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n/an/a 55n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069697
PNG
(CHEMBL2356172)
Show SMILES CC(C)NC(=O)Nc1ccc2O[C@@H](CN(C)S(=O)(=O)c3ccc(Cl)cc3)[C@H](C)CN([C@H](C)CO)C(=O)c2c1
Show InChI InChI=1S/C26H35ClN4O6S/c1-16(2)28-26(34)29-20-8-11-23-22(12-20)25(33)31(18(4)15-32)13-17(3)24(37-23)14-30(5)38(35,36)21-9-6-19(27)7-10-21/h6-12,16-18,24,32H,13-15H2,1-5H3,(H2,28,29,34)/t17-,18-,24+/m1/s1
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n/an/a 60n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069714
PNG
(CHEMBL2356554)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)Nc3ccc(F)cc3)cc2C1=O
Show InChI InChI=1S/C29H32ClFN4O6S/c1-18-15-35(19(2)17-36)28(37)25-14-23(33-29(38)32-22-8-6-21(31)7-9-22)10-13-26(25)41-27(18)16-34(3)42(39,40)24-11-4-20(30)5-12-24/h4-14,18-19,27,36H,15-17H2,1-3H3,(H2,32,33,38)/t18-,19-,27+/m1/s1
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n/an/a 92n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088257
PNG
(CHEMBL1612527)
Show SMILES COc1ccc(cc1OC)-c1nnn(CC(=O)N(C(C)C(=O)NC2CCCC2)C2CCCC2)n1
Show InChI InChI=1S/C24H34N6O4/c1-16(24(32)25-18-8-4-5-9-18)30(19-10-6-7-11-19)22(31)15-29-27-23(26-28-29)17-12-13-20(33-2)21(14-17)34-3/h12-14,16,18-19H,4-11,15H2,1-3H3,(H,25,32)
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n/an/a 110n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088268
PNG
(CHEMBL3427488)
Show SMILES CC(N(C1CCCCC1)C(=O)Cn1nnc(n1)-c1ccc(F)cc1)C(=O)NC1CCCC1
Show InChI InChI=1S/C23H31FN6O2/c1-16(23(32)25-19-7-5-6-8-19)30(20-9-3-2-4-10-20)21(31)15-29-27-22(26-28-29)17-11-13-18(24)14-12-17/h11-14,16,19-20H,2-10,15H2,1H3,(H,25,32)
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n/an/a 130n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088282
PNG
(CHEMBL3427474)
Show SMILES COc1ccc(cc1OC)-c1nc(CC(=O)N(C(C)C(=O)NC2CCCC2)C2CCCCC2)co1
Show InChI InChI=1S/C27H37N3O5/c1-18(26(32)28-20-9-7-8-10-20)30(22-11-5-4-6-12-22)25(31)16-21-17-35-27(29-21)19-13-14-23(33-2)24(15-19)34-3/h13-15,17-18,20,22H,4-12,16H2,1-3H3,(H,28,32)
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n/an/a 130n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088275
PNG
(CHEMBL3427481)
Show SMILES CC(N(C1CCCCC1)C(=O)Cn1nnc(n1)-c1ccc(Cl)cc1)C(=O)NC1CCCC1
Show InChI InChI=1S/C23H31ClN6O2/c1-16(23(32)25-19-7-5-6-8-19)30(20-9-3-2-4-10-20)21(31)15-29-27-22(26-28-29)17-11-13-18(24)14-12-17/h11-14,16,19-20H,2-10,15H2,1H3,(H,25,32)
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n/an/a 170n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069703
PNG
(CHEMBL2361909)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccccc2Cl)Oc2ccc(NC(=O)C3CCCCC3)cc2C1=O
Show InChI InChI=1S/C29H38ClN3O6S/c1-19-16-33(20(2)18-34)29(36)23-15-22(31-28(35)21-9-5-4-6-10-21)13-14-25(23)39-26(19)17-32(3)40(37,38)27-12-8-7-11-24(27)30/h7-8,11-15,19-21,26,34H,4-6,9-10,16-18H2,1-3H3,(H,31,35)/t19-,20-,26+/m1/s1
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n/an/a 180n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069750
PNG
(CHEMBL2357128)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O
Show InChI InChI=1S/C33H37ClN4O6S/c1-21-17-38(22(2)20-39)33(41)28-16-25(35-32(40)15-23-18-36(3)29-8-6-5-7-27(23)29)11-14-30(28)44-31(21)19-37(4)45(42,43)26-12-9-24(34)10-13-26/h5-14,16,18,21-22,31,39H,15,17,19-20H2,1-4H3,(H,35,40)/t21-,22-,31+/m1/s1
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n/an/a 180n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088278
PNG
(CHEMBL3427478)
Show SMILES COc1cccc(c1)-c1nnn(CC(=O)N(C(C)C(=O)NC2CCCC2)C2CCCCC2)n1
Show InChI InChI=1S/C24H34N6O3/c1-17(24(32)25-19-10-6-7-11-19)30(20-12-4-3-5-13-20)22(31)16-29-27-23(26-28-29)18-9-8-14-21(15-18)33-2/h8-9,14-15,17,19-20H,3-7,10-13,16H2,1-2H3,(H,25,32)
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n/an/a 180n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088274
PNG
(CHEMBL3427482)
Show SMILES CC(N(C1CCCCC1)C(=O)Cn1nnc(n1)-c1ccc(Cl)c(Cl)c1)C(=O)NC1CCCC1
Show InChI InChI=1S/C23H30Cl2N6O2/c1-15(23(33)26-17-7-5-6-8-17)31(18-9-3-2-4-10-18)21(32)14-30-28-22(27-29-30)16-11-12-19(24)20(25)13-16/h11-13,15,17-18H,2-10,14H2,1H3,(H,26,33)
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n/an/a 180n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069707
PNG
(CHEMBL2362430)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NS(=O)(=O)c3c(C)noc3C)cc2C1=O
Show InChI InChI=1S/C27H33ClN4O8S2/c1-16-13-32(17(2)15-33)27(34)23-12-21(30-41(35,36)26-18(3)29-40-19(26)4)8-11-24(23)39-25(16)14-31(5)42(37,38)22-9-6-20(28)7-10-22/h6-12,16-17,25,30,33H,13-15H2,1-5H3/t16-,17-,25+/m1/s1
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n/an/a 190n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088287
PNG
(CHEMBL3427471)
Show SMILES COc1ccc(cc1OC)-c1nnn(CC(=O)N(C(C)C(=O)NC2CCCCC2)C2CCCCC2)n1
Show InChI InChI=1S/C26H38N6O4/c1-18(26(34)27-20-10-6-4-7-11-20)32(21-12-8-5-9-13-21)24(33)17-31-29-25(28-30-31)19-14-15-22(35-2)23(16-19)36-3/h14-16,18,20-21H,4-13,17H2,1-3H3,(H,27,34)
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n/an/a 200n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069741
PNG
(CHEMBL3400863)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccccc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C33H38N4O6S/c1-22-18-37(23(2)21-38)33(40)28-17-25(34-32(39)16-24-19-35(3)29-13-9-8-12-27(24)29)14-15-30(28)43-31(22)20-36(4)44(41,42)26-10-6-5-7-11-26/h5-15,17,19,22-23,31,38H,16,18,20-21H2,1-4H3,(H,34,39)/t22-,23-,31+/m1/s1
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n/an/a 220n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088273
PNG
(CHEMBL3427483)
Show SMILES CC(N(C1CCCCC1)C(=O)Cn1nnc(n1)-c1ccc2OC(F)(F)Oc2c1)C(=O)NC1CCCC1
Show InChI InChI=1S/C24H30F2N6O4/c1-15(23(34)27-17-7-5-6-8-17)32(18-9-3-2-4-10-18)21(33)14-31-29-22(28-30-31)16-11-12-19-20(13-16)36-24(25,26)35-19/h11-13,15,17-18H,2-10,14H2,1H3,(H,27,34)
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n/an/a 230n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069697
PNG
(CHEMBL2356172)
Show SMILES CC(C)NC(=O)Nc1ccc2O[C@@H](CN(C)S(=O)(=O)c3ccc(Cl)cc3)[C@H](C)CN([C@H](C)CO)C(=O)c2c1
Show InChI InChI=1S/C26H35ClN4O6S/c1-16(2)28-26(34)29-20-8-11-23-22(12-20)25(33)31(18(4)15-32)13-17(3)24(37-23)14-30(5)38(35,36)21-9-6-19(27)7-10-21/h6-12,16-18,24,32H,13-15H2,1-5H3,(H2,28,29,34)/t17-,18-,24+/m1/s1
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n/an/a 250n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in uptake of [3H]CE from [3H]CE-HDL by by liquid scintillation count...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069697
PNG
(CHEMBL2356172)
Show SMILES CC(C)NC(=O)Nc1ccc2O[C@@H](CN(C)S(=O)(=O)c3ccc(Cl)cc3)[C@H](C)CN([C@H](C)CO)C(=O)c2c1
Show InChI InChI=1S/C26H35ClN4O6S/c1-16(2)28-26(34)29-20-8-11-23-22(12-20)25(33)31(18(4)15-32)13-17(3)24(37-23)14-30(5)38(35,36)21-9-6-19(27)7-10-21/h6-12,16-18,24,32H,13-15H2,1-5H3,(H2,28,29,34)/t17-,18-,24+/m1/s1
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n/an/a 250n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of [3H]cholesteryl ester uptake into cells after 2 to 3 hrs by liquid sci...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069722
PNG
(CHEMBL3400876)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)CCC(F)(F)F)cc2C1=O |r|
Show InChI InChI=1S/C26H31ClF3N3O6S/c1-16-13-33(17(2)15-34)25(36)21-12-19(31-24(35)10-11-26(28,29)30)6-9-22(21)39-23(16)14-32(3)40(37,38)20-7-4-18(27)5-8-20/h4-9,12,16-17,23,34H,10-11,13-15H2,1-3H3,(H,31,35)/t16-,17-,23+/m1/s1
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n/an/a 260n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069713
PNG
(CHEMBL3400882)
Show SMILES COc1ccc(NC(=O)Nc2ccc3O[C@@H](CN(C)S(=O)(=O)c4ccc(Cl)cc4)[C@H](C)CN([C@H](C)CO)C(=O)c3c2)cc1 |r|
Show InChI InChI=1S/C30H35ClN4O7S/c1-19-16-35(20(2)18-36)29(37)26-15-23(33-30(38)32-22-7-10-24(41-4)11-8-22)9-14-27(26)42-28(19)17-34(3)43(39,40)25-12-5-21(31)6-13-25/h5-15,19-20,28,36H,16-18H2,1-4H3,(H2,32,33,38)/t19-,20-,28+/m1/s1
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n/an/a 300n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069711
PNG
(CHEMBL2356546)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)NC3CCCCC3)cc2C1=O
Show InChI InChI=1S/C29H39ClN4O6S/c1-19-16-34(20(2)18-35)28(36)25-15-23(32-29(37)31-22-7-5-4-6-8-22)11-14-26(25)40-27(19)17-33(3)41(38,39)24-12-9-21(30)10-13-24/h9-15,19-20,22,27,35H,4-8,16-18H2,1-3H3,(H2,31,32,37)/t19-,20-,27+/m1/s1
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n/an/a 350n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088272
PNG
(CHEMBL3427484)
Show SMILES CC(N(C1CCCCC1)C(=O)Cn1nnc(n1)-c1ccccc1)C(=O)NC1CCCC1
Show InChI InChI=1S/C23H32N6O2/c1-17(23(31)24-19-12-8-9-13-19)29(20-14-6-3-7-15-20)21(30)16-28-26-22(25-27-28)18-10-4-2-5-11-18/h2,4-5,10-11,17,19-20H,3,6-9,12-16H2,1H3,(H,24,31)
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n/an/a 370n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088271
PNG
(CHEMBL3427485)
Show SMILES CC(N(C1CCCCC1)C(=O)Cn1nnc(n1)-c1cccc(F)c1)C(=O)NC1CCCC1
Show InChI InChI=1S/C23H31FN6O2/c1-16(23(32)25-19-10-5-6-11-19)30(20-12-3-2-4-13-20)21(31)15-29-27-22(26-28-29)17-8-7-9-18(24)14-17/h7-9,14,16,19-20H,2-6,10-13,15H2,1H3,(H,25,32)
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n/an/a 380n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088288
PNG
(CHEMBL3427472)
Show SMILES COc1ccc(cc1OC)-c1nnn(CC(=O)N(C(C)C(=O)NC2CC2)C2CCCCC2)n1
Show InChI InChI=1S/C23H32N6O4/c1-15(23(31)24-17-10-11-17)29(18-7-5-4-6-8-18)21(30)14-28-26-22(25-27-28)16-9-12-19(32-2)20(13-16)33-3/h9,12-13,15,17-18H,4-8,10-11,14H2,1-3H3,(H,24,31)
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n/an/a 420n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088269
PNG
(CHEMBL3427487)
Show SMILES CC(N(C1CCCCC1)C(=O)Cn1nnc(n1)-c1ccc(C)cc1)C(=O)NC1CCCC1
Show InChI InChI=1S/C24H34N6O2/c1-17-12-14-19(15-13-17)23-26-28-29(27-23)16-22(31)30(21-10-4-3-5-11-21)18(2)24(32)25-20-8-6-7-9-20/h12-15,18,20-21H,3-11,16H2,1-2H3,(H,25,32)
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n/an/a 490n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069743
PNG
(CHEMBL1710685)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(F)cc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O
Show InChI InChI=1S/C33H37FN4O6S/c1-21-17-38(22(2)20-39)33(41)28-16-25(35-32(40)15-23-18-36(3)29-8-6-5-7-27(23)29)11-14-30(28)44-31(21)19-37(4)45(42,43)26-12-9-24(34)10-13-26/h5-14,16,18,21-22,31,39H,15,17,19-20H2,1-4H3,(H,35,40)/t21-,22-,31+/m1/s1
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n/an/a 560n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088270
PNG
(CHEMBL3427486)
Show SMILES CC(N(C1CCCCC1)C(=O)Cn1nnc(n1)-c1ccccc1F)C(=O)NC1CCCC1
Show InChI InChI=1S/C23H31FN6O2/c1-16(23(32)25-17-9-5-6-10-17)30(18-11-3-2-4-12-18)21(31)15-29-27-22(26-28-29)19-13-7-8-14-20(19)24/h7-8,13-14,16-18H,2-6,9-12,15H2,1H3,(H,25,32)
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n/an/a 620n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069702
PNG
(CHEMBL3402562)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(cc2C1=O)N(C)C |r|
Show InChI InChI=1S/C24H32ClN3O5S/c1-16-13-28(17(2)15-29)24(30)21-12-19(26(3)4)8-11-22(21)33-23(16)14-27(5)34(31,32)20-9-6-18(25)7-10-20/h6-12,16-17,23,29H,13-15H2,1-5H3/t16-,17-,23+/m1/s1
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n/an/a 630n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069726
PNG
(CHEMBL2359464)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)Cc2ccc(cc2)C(F)(F)F)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O
Show InChI InChI=1S/C35H39F3N4O4/c1-22-17-42(23(2)21-43)34(45)29-16-27(39-33(44)15-25-19-41(4)30-8-6-5-7-28(25)30)13-14-31(29)46-32(22)20-40(3)18-24-9-11-26(12-10-24)35(36,37)38/h5-14,16,19,22-23,32,43H,15,17-18,20-21H2,1-4H3,(H,39,44)/t22-,23-,32+/m1/s1
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n/an/a 650n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50323654
PNG
(CHEMBL1208829 | N-(5-tert-butyl-2-methoxy-3-(methy...)
Show SMILES COc1c(NC(=O)C(=O)c2ccc(OCCN3CCOCC3)c3ccccc23)cc(cc1NS(C)(=O)=O)C(C)(C)C
Show InChI InChI=1S/C30H37N3O7S/c1-30(2,3)20-18-24(28(38-4)25(19-20)32-41(5,36)37)31-29(35)27(34)23-10-11-26(22-9-7-6-8-21(22)23)40-17-14-33-12-15-39-16-13-33/h6-11,18-19,32H,12-17H2,1-5H3,(H,31,35)
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n/an/a 770n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of [3H]cholesteryl ester uptake into cells after 2 to 3 hrs by liquid sci...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50323654
PNG
(CHEMBL1208829 | N-(5-tert-butyl-2-methoxy-3-(methy...)
Show SMILES COc1c(NC(=O)C(=O)c2ccc(OCCN3CCOCC3)c3ccccc23)cc(cc1NS(C)(=O)=O)C(C)(C)C
Show InChI InChI=1S/C30H37N3O7S/c1-30(2,3)20-18-24(28(38-4)25(19-20)32-41(5,36)37)31-29(35)27(34)23-10-11-26(22-9-7-6-8-21(22)23)40-17-14-33-12-15-39-16-13-33/h6-11,18-19,32H,12-17H2,1-5H3,(H,31,35)
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n/an/a 770n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in uptake of [3H]CE from [3H]CE-HDL by by liquid scintillation count...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069704
PNG
(CHEMBL2362877)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2cccc(Cl)c2)Oc2ccc(NC(=O)C3CCCCC3)cc2C1=O
Show InChI InChI=1S/C29H38ClN3O6S/c1-19-16-33(20(2)18-34)29(36)25-15-23(31-28(35)21-8-5-4-6-9-21)12-13-26(25)39-27(19)17-32(3)40(37,38)24-11-7-10-22(30)14-24/h7,10-15,19-21,27,34H,4-6,8-9,16-18H2,1-3H3,(H,31,35)/t19-,20-,27+/m1/s1
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n/an/a>800n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088284
PNG
(CHEMBL3427468)
Show SMILES COc1ccc(cc1OC)-c1nnn(CC(=O)N(C(C)C(=O)NC(C)C)C2CCCCC2)n1
Show InChI InChI=1S/C23H34N6O4/c1-15(2)24-23(31)16(3)29(18-9-7-6-8-10-18)21(30)14-28-26-22(25-27-28)17-11-12-19(32-4)20(13-17)33-5/h11-13,15-16,18H,6-10,14H2,1-5H3,(H,24,31)
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n/an/a 810n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088264
PNG
(CHEMBL3427492)
Show SMILES CC(N(C1CCOCC1)C(=O)Cn1nnc(n1)-c1ccc2OCOc2c1)C(=O)NC1CCCC1
Show InChI InChI=1S/C23H30N6O5/c1-15(23(31)24-17-4-2-3-5-17)29(18-8-10-32-11-9-18)21(30)13-28-26-22(25-27-28)16-6-7-19-20(12-16)34-14-33-19/h6-7,12,15,17-18H,2-5,8-11,13-14H2,1H3,(H,24,31)
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n/an/a 840n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069724
PNG
(CHEMBL3400874)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)Cc2ccc3OCOc3c2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C35H40N4O6/c1-22-16-39(23(2)20-40)35(42)28-15-26(36-34(41)14-25-18-38(4)29-8-6-5-7-27(25)29)10-12-30(28)45-33(22)19-37(3)17-24-9-11-31-32(13-24)44-21-43-31/h5-13,15,18,22-23,33,40H,14,16-17,19-21H2,1-4H3,(H,36,41)/t22-,23-,33+/m1/s1
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n/an/a 890n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069747
PNG
(CHEMBL3400860)
Show SMILES C[C@@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C33H37ClN4O6S/c1-21-17-38(22(2)20-39)33(41)28-16-25(35-32(40)15-23-18-36(3)29-8-6-5-7-27(23)29)11-14-30(28)44-31(21)19-37(4)45(42,43)26-12-9-24(34)10-13-26/h5-14,16,18,21-22,31,39H,15,17,19-20H2,1-4H3,(H,35,40)/t21-,22+,31+/m1/s1
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n/an/a 910n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069723
PNG
(CHEMBL3400875)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)Cc2ccncc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C33H39N5O4/c1-22-17-38(23(2)21-39)33(41)28-16-26(35-32(40)15-25-19-37(4)29-8-6-5-7-27(25)29)9-10-30(28)42-31(22)20-36(3)18-24-11-13-34-14-12-24/h5-14,16,19,22-23,31,39H,15,17-18,20-21H2,1-4H3,(H,35,40)/t22-,23-,31+/m1/s1
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n/an/a 1.30E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088265
PNG
(CHEMBL3427491)
Show SMILES COc1ccc(cc1OC)-c1nnn(CC(=O)N(CC2CCCCC2)C(C)C(=O)NC2CCCC2)n1
Show InChI InChI=1S/C26H38N6O4/c1-18(26(34)27-21-11-7-8-12-21)31(16-19-9-5-4-6-10-19)24(33)17-32-29-25(28-30-32)20-13-14-22(35-2)23(15-20)36-3/h13-15,18-19,21H,4-12,16-17H2,1-3H3,(H,27,34)
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n/an/a 1.60E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088194
PNG
(CHEMBL3427498)
Show SMILES C[C@H](N(C1CCCCC1)C(=O)Cn1nnc(n1)-c1ccc2OCOc2c1)C(=O)NC1CCCC1 |r|
Show InChI InChI=1S/C24H32N6O4/c1-16(24(32)25-18-7-5-6-8-18)30(19-9-3-2-4-10-19)22(31)14-29-27-23(26-28-29)17-11-12-20-21(13-17)34-15-33-20/h11-13,16,18-19H,2-10,14-15H2,1H3,(H,25,32)/t16-/m0/s1
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n/an/a 1.60E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069728
PNG
(CHEMBL3400872)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)Cc2ccccc2)Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C1=O |r|
Show InChI InChI=1S/C34H40N4O4/c1-23-18-38(24(2)22-39)34(41)29-17-27(35-33(40)16-26-20-37(4)30-13-9-8-12-28(26)30)14-15-31(29)42-32(23)21-36(3)19-25-10-6-5-7-11-25/h5-15,17,20,23-24,32,39H,16,18-19,21-22H2,1-4H3,(H,35,40)/t23-,24-,32+/m1/s1
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n/an/a 1.60E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069710
PNG
(CHEMBL3402559)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NS(C)(=O)=O)cc2C1=O |r|
Show InChI InChI=1S/C23H30ClN3O7S2/c1-15-12-27(16(2)14-28)23(29)20-11-18(25-35(4,30)31)7-10-21(20)34-22(15)13-26(3)36(32,33)19-8-5-17(24)6-9-19/h5-11,15-16,22,25,28H,12-14H2,1-4H3/t15-,16-,22+/m1/s1
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n/an/a 1.60E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50088289
PNG
(CHEMBL3427473)
Show SMILES COc1ccc(cc1OC)-c1nnn(CC(=O)N(C(C)C(=O)N(C)C2CCCC2)C2CCCCC2)n1
Show InChI InChI=1S/C26H38N6O4/c1-18(26(34)30(2)20-10-8-9-11-20)32(21-12-6-5-7-13-21)24(33)17-31-28-25(27-29-31)19-14-15-22(35-3)23(16-19)36-4/h14-16,18,20-21H,5-13,17H2,1-4H3
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n/an/a 1.60E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-BI isoform 1 expressed in CHO cells assessed as reduction in transfer of fluorescent lipid DiI from human HDL particles into c...

Bioorg Med Chem Lett 25: 2594-8 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.074
BindingDB Entry DOI: 10.7270/Q25Q4XTV
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069742
PNG
(CHEMBL3400862)
Show SMILES COc1ccc(cc1)S(=O)(=O)N(C)C[C@@H]1Oc2ccc(NC(=O)Cc3cn(C)c4ccccc34)cc2C(=O)N(C[C@H]1C)[C@H](C)CO |r|
Show InChI InChI=1S/C34H40N4O7S/c1-22-18-38(23(2)21-39)34(41)29-17-25(35-33(40)16-24-19-36(3)30-9-7-6-8-28(24)30)10-15-31(29)45-32(22)20-37(4)46(42,43)27-13-11-26(44-5)12-14-27/h6-15,17,19,22-23,32,39H,16,18,20-21H2,1-5H3,(H,35,40)/t22-,23-,32+/m1/s1
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n/an/a 2.00E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
Scavenger receptor class B member 1


(Mus musculus)		BDBM50069717
PNG
(CHEMBL3400879)
Show SMILES C[C@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)Oc2ccc(NC(=O)C3CC3)cc2C1=O |r|
Show InChI InChI=1S/C26H32ClN3O6S/c1-16-13-30(17(2)15-31)26(33)22-12-20(28-25(32)18-4-5-18)8-11-23(22)36-24(16)14-29(3)37(34,35)21-9-6-19(27)7-10-21/h6-12,16-18,24,31H,4-5,13-15H2,1-3H3,(H,28,32)/t16-,17-,24+/m1/s1
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n/an/a 2.10E+3n/an/an/an/an/an/a



Marquette University

Curated by ChEMBL


Assay Description
Inhibition of mouse SR-B1 overexpressed in CHO cells assessed as inhibition of transfer of the fluorescent lipid DiI from HDL particles to cells afte...

Bioorg Med Chem Lett 25: 2100-5 (2015)


Article DOI: 10.1016/j.bmcl.2015.03.073
BindingDB Entry DOI: 10.7270/Q2P84DKP
More data for this
Ligand-Target Pair
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