Compile Data Set for Download or QSAR

Found 1815 hits of ic50 data for polymerid = 50006823   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324798 (9-(4-(2H-1,2,3-triazol-2- | US10189841, Compound I...) Show SMILES FC(F)Oc1ncccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3nccn3)c2n1 Show InChI InChI=1S/C20H14F2N8O2/c21-19(22)32-18-14(2-1-7-23-18)16-24-10-15-17(28-16)29(20(31)27-15)11-12-3-5-13(6-4-12)30-25-8-9-26-30/h1-10,19H,11H2,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325311 (US10189841, Compound I-517 | US10399980, Compound ...) Show SMILES CC(C)c1cccnc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-n3cccn3)c2n1 Show InChI InChI=1S/C24H23N7O/c1-16(2)19-6-4-11-25-21(19)22-26-14-20-23(28-22)30(24(32)29(20)3)15-17-7-9-18(10-8-17)31-13-5-12-27-31/h4-14,16H,15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324809 (9-(4-(2H-1,2,3-triazol-2- | US10189841, Compound I...) Show SMILES CC(C)Oc1cc(F)ccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3nccn3)c2n1 Show InChI InChI=1S/C23H20FN7O2/c1-14(2)33-20-11-16(24)5-8-18(20)21-25-12-19-22(29-21)30(23(32)28-19)13-15-3-6-17(7-4-15)31-26-9-10-27-31/h3-12,14H,13H2,1-2H3,(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324810 (9-(4-(2H-1,2,3-triazol-2- | US10189841, Compound I...) Show SMILES COc1c(F)cccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3nccn3)c2n1 Show InChI InChI=1S/C21H16FN7O2/c1-31-18-15(3-2-4-16(18)22)19-23-11-17-20(27-19)28(21(30)26-17)12-13-5-7-14(8-6-13)29-24-9-10-25-29/h2-11H,12H2,1H3,(H,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324811 (9-(4-(1H-pyrazol-1- | US10189841, Compound I-17 | ...) Show SMILES CC(C)c1ccncc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-n3cccn3)c2n1 Show InChI InChI=1S/C24H23N7O/c1-16(2)19-9-11-25-13-20(19)22-26-14-21-23(28-22)30(24(32)29(21)3)15-17-5-7-18(8-6-17)31-12-4-10-27-31/h4-14,16H,15H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324822 (9-(4-(1H-pyrazol-1- | US10189841, Compound I-28 | ...) Show SMILES CC(C)c1ncncc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3cccn3)c2n1 Show InChI InChI=1S/C22H20N8O/c1-14(2)19-17(10-23-13-25-19)20-24-11-18-21(28-20)29(22(31)27-18)12-15-4-6-16(7-5-15)30-9-3-8-26-30/h3-11,13-14H,12H2,1-2H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324906 (9-(((1r,4r)-4-(3,5- | US10189841, Compound I-112 |...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(C[C@H]3CC[C@@H](CC3)n3nc(C)cc3C)c2n1 |r,wU:22.26,wD:19.19,(-8.63,3.74,;-7.3,2.97,;-5.97,3.74,;-7.3,1.43,;-8.63,.66,;-8.63,-.88,;-7.3,-1.65,;-5.97,-.88,;-5.97,.66,;-4.63,1.43,;-4.63,2.97,;-3.3,3.74,;-1.97,2.97,;-.5,3.44,;-.1,4.93,;.4,2.2,;1.94,2.2,;-.5,.95,;-.1,-.54,;1.39,-.94,;1.78,-2.42,;3.27,-2.82,;4.36,-1.73,;3.96,-.25,;2.47,.15,;5.85,-2.13,;6.32,-3.6,;7.86,-3.6,;8.63,-4.93,;8.34,-2.13,;7.09,-1.23,;7.09,.31,;-1.97,1.43,;-3.3,.66,)| Show InChI InChI=1S/C27H34N6O/c1-17(2)22-8-6-7-9-23(22)25-28-15-24-26(29-25)32(27(34)31(24)5)16-20-10-12-21(13-11-20)33-19(4)14-18(3)30-33/h6-9,14-15,17,20-21H,10-13,16H2,1-5H3/t20-,21-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324938 (2-(2-isopropylphenyl)-9-(1- | US10189841, Compound...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(C3CCN(CC3)c3cccnc3)c2n1 Show InChI InChI=1S/C24H26N6O/c1-16(2)19-7-3-4-8-20(19)22-26-15-21-23(28-22)30(24(31)27-21)17-9-12-29(13-10-17)18-6-5-11-25-14-18/h3-8,11,14-17H,9-10,12-13H2,1-2H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324947 (2-(2-isopropylphenyl)-9-(4- | US10189841, Compound...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(CN4CCOCC4)cc3)c2n1 Show InChI InChI=1S/C26H29N5O2/c1-18(2)21-5-3-4-6-22(21)24-27-15-23-25(29-24)31(26(32)28-23)17-20-9-7-19(8-10-20)16-30-11-13-33-14-12-30/h3-10,15,18H,11-14,16-17H2,1-2H3,(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324948 (9-(4-(1H-1,2,4-triazol-1- | US10189841, Compound I...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3cncn3)c2n1 Show InChI InChI=1S/C23H21N7O/c1-15(2)18-5-3-4-6-19(18)21-25-11-20-22(28-21)29(23(31)27-20)12-16-7-9-17(10-8-16)30-14-24-13-26-30/h3-11,13-15H,12H2,1-2H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324950 ((S)-2-(2-isopropylphenyl)- | US10189841, Compound ...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n([C@@H](C)c3ccccc3)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324976 (2-(2-isopropylphenyl)-9- | US10189841, Compound I-...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc4n(C)cnc4c3)c2n1 Show InChI InChI=1S/C23H22N6O/c1-14(2)16-6-4-5-7-17(16)21-24-11-19-22(27-21)29(23(30)26-19)12-15-8-9-20-18(10-15)25-13-28(20)3/h4-11,13-14H,12H2,1-3H3,(H,26,30)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM324977 (2-(2-isopropylphenyl)-9-(4- | US10189841, Compound...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)S(C)(=O)=O)c2n1 Show InChI InChI=1S/C22H22N4O3S/c1-14(2)17-6-4-5-7-18(17)20-23-12-19-21(25-20)26(22(27)24-19)13-15-8-10-16(11-9-15)30(3,28)29/h4-12,14H,13H2,1-3H3,(H,24,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325028 (9-(4-(3-(dimethylamino)propoxy)benzyl)-2-(2- | US1...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(OCCCN(C)C)cc3)c2n1 Show InChI InChI=1S/C27H33N5O2/c1-19(2)22-9-6-7-10-23(22)25-28-17-24-26(29-25)32(27(33)31(24)5)18-20-11-13-21(14-12-20)34-16-8-15-30(3)4/h6-7,9-14,17,19H,8,15-16,18H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325033 (9-(3-(cyclopropylmethoxy)benzyl)-2-(2- | US1018984...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3cccc(OCC4CC4)c3)c2n1 Show InChI InChI=1S/C26H28N4O2/c1-17(2)21-9-4-5-10-22(21)24-27-14-23-25(28-24)30(26(31)29(23)3)15-19-7-6-8-20(13-19)32-16-18-11-12-18/h4-10,13-14,17-18H,11-12,15-16H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325036 (2-(2-isopropylphenyl)-7-methyl-9-(3-(pyridin-2- | ...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3cccc(OCc4ccccn4)c3)c2n1 Show InChI InChI=1S/C28H27N5O2/c1-19(2)23-12-4-5-13-24(23)26-30-16-25-27(31-26)33(28(34)32(25)3)17-20-9-8-11-22(15-20)35-18-21-10-6-7-14-29-21/h4-16,19H,17-18H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325038 (9-(3-(2-(dimethylamino)ethoxy)benzyl)-2-(2- | US10...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3cccc(OCCN(C)C)c3)c2n1 Show InChI InChI=1S/C26H31N5O2/c1-18(2)21-11-6-7-12-22(21)24-27-16-23-25(28-24)31(26(32)30(23)5)17-19-9-8-10-20(15-19)33-14-13-29(3)4/h6-12,15-16,18H,13-14,17H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325039 (9-(3-(3-(dimethylamino)propoxy)benzyl)-2-(2- | US1...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3cccc(OCCCN(C)C)c3)c2n1 Show InChI InChI=1S/C27H33N5O2/c1-19(2)22-12-6-7-13-23(22)25-28-17-24-26(29-25)32(27(33)31(24)5)18-20-10-8-11-21(16-20)34-15-9-14-30(3)4/h6-8,10-13,16-17,19H,9,14-15,18H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325040 (9-(3-cyclobutoxybenzyl)-2-(2-isopropylphenyl)-7- |...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3cccc(OC4CCC4)c3)c2n1 Show InChI InChI=1S/C26H28N4O2/c1-17(2)21-12-4-5-13-22(21)24-27-15-23-25(28-24)30(26(31)29(23)3)16-18-8-6-11-20(14-18)32-19-9-7-10-19/h4-6,8,11-15,17,19H,7,9-10,16H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325048 (2-(4-(4-((2-(2-isopropylphenyl)-8-oxo-7,8-dihydro-...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-c3cnn(C)c3CC(O)=O)c2n1 Show InChI InChI=1S/C27H26N6O3/c1-16(2)19-6-4-5-7-20(19)25-28-14-22-26(31-25)33(27(36)30-22)15-17-8-10-18(11-9-17)21-13-29-32(3)23(21)12-24(34)35/h4-11,13-14,16H,12,15H2,1-3H3,(H,30,36)(H,34,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325079 (2-(2-isopropylphenyl)-7-methyl-9-(4-(1-methyl-1H- ...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)-c3cnnn3C)c2n1 Show InChI InChI=1S/C25H25N7O/c1-16(2)19-7-5-6-8-20(19)23-26-13-22-24(28-23)32(25(33)30(22)3)15-17-9-11-18(12-10-17)21-14-27-29-31(21)4/h5-14,16H,15H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325132 (9-(4-(4-(2-aminopropan-2-yl)-1H-1,2,3-triazol-1- |...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3cc(nn3)C(C)(C)N)c2n1 Show InChI InChI=1S/C26H28N8O/c1-16(2)19-7-5-6-8-20(19)23-28-13-21-24(30-23)33(25(35)29-21)14-17-9-11-18(12-10-17)34-15-22(31-32-34)26(3,4)27/h5-13,15-16H,14,27H2,1-4H3,(H,29,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325133 (9-(4-(4-((dimethylamino)methyl)-1H-1,2,3-triazol-1...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3cc(CN(C)C)nn3)c2n1 Show InChI InChI=1S/C26H28N8O/c1-17(2)21-7-5-6-8-22(21)24-27-13-23-25(29-24)33(26(35)28-23)14-18-9-11-20(12-10-18)34-16-19(30-31-34)15-32(3)4/h5-13,16-17H,14-15H2,1-4H3,(H,28,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325140 (9-(4-(4-((diethylamino)methyl)-1H-1,2,3-triazol-1-...) Show SMILES CCN(CC)Cc1cn(nn1)-c1ccc(Cn2c3nc(ncc3[nH]c2=O)-c2ccccc2C(C)C)cc1 Show InChI InChI=1S/C28H32N8O/c1-5-34(6-2)17-21-18-36(33-32-21)22-13-11-20(12-14-22)16-35-27-25(30-28(35)37)15-29-26(31-27)24-10-8-7-9-23(24)19(3)4/h7-15,18-19H,5-6,16-17H2,1-4H3,(H,30,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325141 ((R)-9-(4-(4-(1-hydroxyethyl)-1H-1,2,3-triazol-1- |...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3cc(nn3)[C@@H](C)O)c2n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325142 (9-(4-(4-(3-aminopentan-3-yl)-1H-1,2,3-triazol-1- |...) Show SMILES CCC(N)(CC)c1cn(nn1)-c1ccc(Cn2c3nc(ncc3[nH]c2=O)-c2ccccc2C(C)C)cc1 Show InChI InChI=1S/C28H32N8O/c1-5-28(29,6-2)24-17-36(34-33-24)20-13-11-19(12-14-20)16-35-26-23(31-27(35)37)15-30-25(32-26)22-10-8-7-9-21(22)18(3)4/h7-15,17-18H,5-6,16,29H2,1-4H3,(H,31,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325144 (2-(2-isopropylphenyl)-9-(4-(4-((methylsulfonyl)met...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3cc(CS(C)(=O)=O)nn3)c2n1 Show InChI InChI=1S/C25H25N7O3S/c1-16(2)20-6-4-5-7-21(20)23-26-12-22-24(28-23)31(25(33)27-22)13-17-8-10-19(11-9-17)32-14-18(29-30-32)15-36(3,34)35/h4-12,14,16H,13,15H2,1-3H3,(H,27,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325171 (9-(4-(3-hydroxyazetidine-1-carbonyl)benzyl)-2-(2- ...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)C(=O)N3CC(O)C3)c2n1 Show InChI InChI=1S/C25H25N5O3/c1-15(2)19-5-3-4-6-20(19)22-26-11-21-23(28-22)30(25(33)27-21)12-16-7-9-17(10-8-16)24(32)29-13-18(31)14-29/h3-11,15,18,31H,12-14H2,1-2H3,(H,27,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325202 (N-(2-(dimethylamino)ethyl)-4-((2-(2- | US10189841,...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)C(=O)NCCN(C)C)c2n1 Show InChI InChI=1S/C26H30N6O2/c1-17(2)20-7-5-6-8-21(20)23-28-15-22-24(30-23)32(26(34)29-22)16-18-9-11-19(12-10-18)25(33)27-13-14-31(3)4/h5-12,15,17H,13-14,16H2,1-4H3,(H,27,33)(H,29,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325203 (4-((2-(2-isopropylphenyl)-8-oxo-7,8-dihydro-9H- | ...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)C(=O)NCCN3CCCCC3)c2n1 Show InChI InChI=1S/C29H34N6O2/c1-20(2)23-8-4-5-9-24(23)26-31-18-25-27(33-26)35(29(37)32-25)19-21-10-12-22(13-11-21)28(36)30-14-17-34-15-6-3-7-16-34/h4-5,8-13,18,20H,3,6-7,14-17,19H2,1-2H3,(H,30,36)(H,32,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325204 (2-(2-isopropylphenyl)-9-(4-(4-methylpiperazine-1- ...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)C(=O)N3CCN(C)CC3)c2n1 Show InChI InChI=1S/C27H30N6O2/c1-18(2)21-6-4-5-7-22(21)24-28-16-23-25(30-24)33(27(35)29-23)17-19-8-10-20(11-9-19)26(34)32-14-12-31(3)13-15-32/h4-11,16,18H,12-15,17H2,1-3H3,(H,29,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325229 (2-(2-isopropylpyridin- | US10189841, Compound I-43...) Show SMILES CC(C)c1ncccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3ccc(n3)C3CCNCC3)c2n1 Show InChI InChI=1S/C28H30N8O/c1-18(2)25-22(4-3-12-30-25)26-31-16-24-27(33-26)35(28(37)32-24)17-19-5-7-21(8-6-19)36-15-11-23(34-36)20-9-13-29-14-10-20/h3-8,11-12,15-16,18,20,29H,9-10,13-14,17H2,1-2H3,(H,32,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325236 (2-(2-isopropylpyridin-3- | US10189841, Compound I-...) Show SMILES CC(C)c1ncccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-n3ccc(n3)C3CCN(C)CC3)c2n1 Show InChI InChI=1S/C29H32N8O/c1-19(2)26-23(5-4-13-30-26)27-31-17-25-28(33-27)36(29(38)32-25)18-20-6-8-22(9-7-20)37-16-12-24(34-37)21-10-14-35(3)15-11-21/h4-9,12-13,16-17,19,21H,10-11,14-15,18H2,1-3H3,(H,32,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325243 (2-(2-isopropylphenyl)-7- | US10189841, Compound I-...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(CC3CCN(CC3)S(=O)(=O)c3cccnc3)c2n1 Show InChI InChI=1S/C26H30N6O3S/c1-18(2)21-8-4-5-9-22(21)24-28-16-23-25(29-24)32(26(33)30(23)3)17-19-10-13-31(14-11-19)36(34,35)20-7-6-12-27-15-20/h4-9,12,15-16,18-19H,10-11,13-14,17H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325247 (N-(4-((2-(2-isopropylphenyl)- | US10189841, Compou...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(NS(=O)(=O)c4ccn(C)n4)cc3)c2n1 Show InChI InChI=1S/C26H27N7O3S/c1-17(2)20-7-5-6-8-21(20)24-27-15-22-25(28-24)33(26(34)32(22)4)16-18-9-11-19(12-10-18)30-37(35,36)23-13-14-31(3)29-23/h5-15,17,30H,16H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325249 (N-(4-((2-(2-isopropylphenyl)- | US10189841, Compou...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(NS(=O)(=O)c4cn(C)c(C)n4)cc3)c2n1 Show InChI InChI=1S/C27H29N7O3S/c1-17(2)21-8-6-7-9-22(21)25-28-14-23-26(30-25)34(27(35)33(23)5)15-19-10-12-20(13-11-19)31-38(36,37)24-16-32(4)18(3)29-24/h6-14,16-17,31H,15H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325256 (9-((1- | US10189841, Compound I-462 | US10399980, ...) Show SMILES CC(C)C(=O)N1CCC(Cn2c3nc(ncc3n(C)c2=O)-c2ccccc2C(C)C)CC1 Show InChI InChI=1S/C25H33N5O2/c1-16(2)19-8-6-7-9-20(19)22-26-14-21-23(27-22)30(25(32)28(21)5)15-18-10-12-29(13-11-18)24(31)17(3)4/h6-9,14,16-18H,10-13,15H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325264 (N-(4-((2-(2- | US10189841, Compound I-470 | US1039...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)N(C)C(=O)c3cc(C)[nH]n3)c2n1 Show InChI InChI=1S/C28H29N7O2/c1-17(2)21-8-6-7-9-22(21)25-29-15-24-26(30-25)35(28(37)34(24)5)16-19-10-12-20(13-11-19)33(4)27(36)23-14-18(3)31-32-23/h6-15,17H,16H2,1-5H3,(H,31,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325265 (N-(4-((2-(2- | US10189841, Compound I-471 | US1039...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(Cc3ccc(cc3)N(C)C(=O)c3cc(C)nn3C)c2n1 Show InChI InChI=1S/C29H31N7O2/c1-18(2)22-9-7-8-10-23(22)26-30-16-25-27(31-26)36(29(38)34(25)5)17-20-11-13-21(14-12-20)33(4)28(37)24-15-19(3)32-35(24)6/h7-16,18H,17H2,1-6H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325269 (9-((4-fluoro-1- | US10189841, Compound I-475 | US1...) Show SMILES CC(C)C(=O)N1CCC(F)(Cn2c3nc(ncc3[nH]c2=O)-c2ccccc2C(C)C)CC1 Show InChI InChI=1S/C24H30FN5O2/c1-15(2)17-7-5-6-8-18(17)20-26-13-19-21(28-20)30(23(32)27-19)14-24(25)9-11-29(12-10-24)22(31)16(3)4/h5-8,13,15-16H,9-12,14H2,1-4H3,(H,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325272 (N-isopropyl-4-((2- | US10189841, Compound I-478 | ...) Show SMILES CC(C)NC(=O)N1CCC(Cn2c3nc(ncc3n(C)c2=O)-c2ccccc2C(C)C)CC1 Show InChI InChI=1S/C25H34N6O2/c1-16(2)19-8-6-7-9-20(19)22-26-14-21-23(28-22)31(25(33)29(21)5)15-18-10-12-30(13-11-18)24(32)27-17(3)4/h6-9,14,16-18H,10-13,15H2,1-5H3,(H,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325273 (N-cyclopropyl-4- | US10189841, Compound I-479 | US...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(CC3CCN(CC3)C(=O)NC3CC3)c2n1 Show InChI InChI=1S/C25H32N6O2/c1-16(2)19-6-4-5-7-20(19)22-26-14-21-23(28-22)31(25(33)29(21)3)15-17-10-12-30(13-11-17)24(32)27-18-8-9-18/h4-7,14,16-18H,8-13,15H2,1-3H3,(H,27,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325279 (1-(4-((2-(2- | US10189841, Compound I-485 | US1039...) Show SMILES COCCNC(=O)N(C)c1ccc(Cn2c3nc(ncc3n(C)c2=O)-c2ccccc2C(C)C)cc1 Show InChI InChI=1S/C27H32N6O3/c1-18(2)21-8-6-7-9-22(21)24-29-16-23-25(30-24)33(27(35)32(23)4)17-19-10-12-20(13-11-19)31(3)26(34)28-14-15-36-5/h6-13,16,18H,14-15,17H2,1-5H3,(H,28,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325281 (4-fluoro-N- | US10189841, Compound I-487 | US10399...) Show SMILES CC(C)NC(=O)N1CCC(F)(Cn2c3nc(ncc3[nH]c2=O)-c2ccccc2C(C)C)CC1 Show InChI InChI=1S/C24H31FN6O2/c1-15(2)17-7-5-6-8-18(17)20-26-13-19-21(29-20)31(23(33)28-19)14-24(25)9-11-30(12-10-24)22(32)27-16(3)4/h5-8,13,15-16H,9-12,14H2,1-4H3,(H,27,32)(H,28,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325286 (9-((1-(1,3,4-thiadiazol-2-yl)piperidin-4-yl)methyl...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(CC3CCN(CC3)c3nncs3)c2n1 Show InChI InChI=1S/C23H27N7OS/c1-15(2)17-6-4-5-7-18(17)20-24-12-19-21(26-20)30(23(31)28(19)3)13-16-8-10-29(11-9-16)22-27-25-14-32-22/h4-7,12,14-16H,8-11,13H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325287 (2-(2-isopropylphenyl)-7-methyl-9-((1-(pyrimidin-2-...) Show SMILES CC(C)c1ccccc1-c1ncc2n(C)c(=O)n(CC3CCN(CC3)c3ncccn3)c2n1 Show InChI InChI=1S/C25H29N7O/c1-17(2)19-7-4-5-8-20(19)22-28-15-21-23(29-22)32(25(33)30(21)3)16-18-9-13-31(14-10-18)24-26-11-6-12-27-24/h4-8,11-12,15,17-18H,9-10,13-14,16H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325296 (US10189841, Compound I-502 | US10399980, Compound ...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(CC3CN(C3)c3nccc(n3)C(F)(F)F)c2n1 Show InChI InChI=1S/C23H22F3N7O/c1-13(2)15-5-3-4-6-16(15)19-28-9-17-20(31-19)33(22(34)29-17)12-14-10-32(11-14)21-27-8-7-18(30-21)23(24,25)26/h3-9,13-14H,10-12H2,1-2H3,(H,29,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325302 (US10189841, Compound I-508 | US10399980, Compound ...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3cnc(cn3)-n3cccn3)c2n1 Show InChI InChI=1S/C22H20N8O/c1-14(2)16-6-3-4-7-17(16)20-25-11-18-21(28-20)29(22(31)27-18)13-15-10-24-19(12-23-15)30-9-5-8-26-30/h3-12,14H,13H2,1-2H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325303 (US10189841, Compound I-509 | US10399980, Compound ...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ncc(cn3)-n3cccn3)c2n1 Show InChI InChI=1S/C22H20N8O/c1-14(2)16-6-3-4-7-17(16)20-25-12-18-21(28-20)29(22(31)27-18)13-19-23-10-15(11-24-19)30-9-5-8-26-30/h3-12,14H,13H2,1-2H3,(H,27,31)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase 1 (Homo sapiens (Human))	BDBM325307 (US10189841, Compound I-513 | US10399980, Compound ...) Show SMILES CC(C)c1ccccc1-c1ncc2[nH]c(=O)n(Cc3ccc(cc3)-c3nnn[nH]3)c2n1 Show InChI InChI=1S/C22H20N8O/c1-13(2)16-5-3-4-6-17(16)20-23-11-18-21(25-20)30(22(31)24-18)12-14-7-9-15(10-8-14)19-26-28-29-27-19/h3-11,13H,12H2,1-2H3,(H,24,31)(H,26,27,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<0.00200	n/a	n/a	n/a	n/a	n/a	n/a
FORMA Therapeutics, Inc. US Patent					Assay Description The HTS assay was performed in a final volume of 20 μL in assay buffer containing 20 mM Tris-HCl (pH 8.0, (1M Tris-HCl, pH 8.0 solution; Corning...				US Patent US10189841 (2019) BindingDB Entry DOI: 10.7270/Q22R3TRR
					More data for this Ligand-Target Pair

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