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Compile Data Set for Download or QSAR

Found 8 hits of ic50 data for polymerid = 50006831   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Krueppel-like factor 10


(Homo sapiens (Human))
BDBM50071809
PNG
(CHEMBL1333704)
Show SMILES Cc1cc(ccc1[N+]([O-])=O)C(=O)Nc1cnc(O)nc1O
Show InChI InChI=1S/C12H10N4O5/c1-6-4-7(2-3-9(6)16(20)21)10(17)14-8-5-13-12(19)15-11(8)18/h2-5H,1H3,(H,14,17)(H2,13,15,18,19)
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n/an/a 1.00E+4n/an/an/an/an/an/a



Beth Israel Deaconess Medical Center

Curated by ChEMBL


Assay Description
Inhibition of human KLF10 expressed in human HeLa cells assessed as reduction in transcriptional activity after 24 hrs by CACCC-responsive promoter d...


J Med Chem 58: 1466-78 (2015)


Article DOI: 10.1021/jm5018187
BindingDB Entry DOI: 10.7270/Q2WM1G3D
More data for this
Ligand-Target Pair
Krueppel-like factor 10


(Homo sapiens (Human))
BDBM50071812
PNG
(CHEMBL3410747)
Show SMILES COc1ccc(cc1)C(=O)COC(=O)c1cc(C)ccc1O
Show InChI InChI=1S/C17H16O5/c1-11-3-8-15(18)14(9-11)17(20)22-10-16(19)12-4-6-13(21-2)7-5-12/h3-9,18H,10H2,1-2H3
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n/an/a 4.00E+4n/an/an/an/an/an/a



Beth Israel Deaconess Medical Center

Curated by ChEMBL


Assay Description
Inhibition of human KLF10 expressed in human HeLa cells assessed as reduction in transcriptional activity after 24 hrs by CACCC-responsive promoter d...


J Med Chem 58: 1466-78 (2015)


Article DOI: 10.1021/jm5018187
BindingDB Entry DOI: 10.7270/Q2WM1G3D
More data for this
Ligand-Target Pair
Krueppel-like factor 10


(Homo sapiens (Human))
BDBM50071813
PNG
(CHEMBL2179992)
Show SMILES Cc1sc2nc(SCC(=O)c3ccc(O)c(O)c3)[nH]c(=O)c2c1C
Show InChI InChI=1S/C16H14N2O4S2/c1-7-8(2)24-15-13(7)14(22)17-16(18-15)23-6-12(21)9-3-4-10(19)11(20)5-9/h3-5,19-20H,6H2,1-2H3,(H,17,18,22)
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n/an/a 4.30E+4n/an/an/an/an/an/a



Beth Israel Deaconess Medical Center

Curated by ChEMBL


Assay Description
Inhibition of human KLF10 expressed in human HeLa cells assessed as reduction in transcriptional activity after 24 hrs by CACCC-responsive promoter d...


J Med Chem 58: 1466-78 (2015)


Article DOI: 10.1021/jm5018187
BindingDB Entry DOI: 10.7270/Q2WM1G3D
More data for this
Ligand-Target Pair
Krueppel-like factor 10


(Homo sapiens (Human))
BDBM50108877
PNG
((3,4-Dihydroxy-5-nitro-phenyl)-p-tolyl-methanone |...)
Show SMILES Cc1ccc(cc1)C(=O)c1cc(O)c(O)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C14H11NO5/c1-8-2-4-9(5-3-8)13(17)10-6-11(15(19)20)14(18)12(16)7-10/h2-7,16,18H,1H3
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n/an/a 5.00E+4n/an/an/an/an/an/a



Beth Israel Deaconess Medical Center

Curated by ChEMBL


Assay Description
Inhibition of human KLF10 expressed in human HeLa cells assessed as reduction in transcriptional activity after 24 hrs by CACCC-responsive promoter d...


J Med Chem 58: 1466-78 (2015)


Article DOI: 10.1021/jm5018187
BindingDB Entry DOI: 10.7270/Q2WM1G3D
More data for this
Ligand-Target Pair
Krueppel-like factor 10


(Homo sapiens (Human))
BDBM50071810
PNG
(CHEMBL3410732)
Show SMILES CC(C)(c1ccc(O)c(CO)c1)c1ccc(O)c(CO)c1
Show InChI InChI=1S/C17H20O4/c1-17(2,13-3-5-15(20)11(7-13)9-18)14-4-6-16(21)12(8-14)10-19/h3-8,18-21H,9-10H2,1-2H3
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n/an/a 1.00E+5n/an/an/an/an/an/a



Beth Israel Deaconess Medical Center

Curated by ChEMBL


Assay Description
Inhibition of human KLF10 expressed in human HeLa cells assessed as reduction in transcriptional activity after 24 hrs by CACCC-responsive promoter d...


J Med Chem 58: 1466-78 (2015)


Article DOI: 10.1021/jm5018187
BindingDB Entry DOI: 10.7270/Q2WM1G3D
More data for this
Ligand-Target Pair
Krueppel-like factor 10


(Homo sapiens (Human))
BDBM50366567
PNG
(ATOMOXETINE)
Show SMILES CNCC[C@@H](Oc1ccccc1C)c1ccccc1 |r|
Show InChI InChI=1S/C17H21NO/c1-14-8-6-7-11-16(14)19-17(12-13-18-2)15-9-4-3-5-10-15/h3-11,17-18H,12-13H2,1-2H3/t17-/m1/s1
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n/an/a 1.00E+5n/an/an/an/an/an/a



Beth Israel Deaconess Medical Center

Curated by ChEMBL


Assay Description
Inhibition of human KLF10 expressed in human HeLa cells assessed as reduction in transcriptional activity after 24 hrs by CACCC-responsive promoter d...


J Med Chem 58: 1466-78 (2015)


Article DOI: 10.1021/jm5018187
BindingDB Entry DOI: 10.7270/Q2WM1G3D
More data for this
Ligand-Target Pair
Krueppel-like factor 10


(Homo sapiens (Human))
BDBM50071811
PNG
(CHEMBL3410641)
Show SMILES Cc1ccc(OCC(=O)c2cc(C)c(O)cc2O)cc1
Show InChI InChI=1S/C16H16O4/c1-10-3-5-12(6-4-10)20-9-16(19)13-7-11(2)14(17)8-15(13)18/h3-8,17-18H,9H2,1-2H3
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CHEMBL
PC cid
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Article
PubMed
n/an/a 1.12E+5n/an/an/an/an/an/a



Beth Israel Deaconess Medical Center

Curated by ChEMBL


Assay Description
Inhibition of human KLF10 expressed in human HeLa cells assessed as reduction in transcriptional activity after 24 hrs by CACCC-responsive promoter d...


J Med Chem 58: 1466-78 (2015)


Article DOI: 10.1021/jm5018187
BindingDB Entry DOI: 10.7270/Q2WM1G3D
More data for this
Ligand-Target Pair
Krueppel-like factor 10


(Homo sapiens (Human))
BDBM50071808
PNG
(CHEMBL490514)
Show SMILES COc1cc(O)c(C(C)=O)c(O)c1
Show InChI InChI=1S/C9H10O4/c1-5(10)9-7(11)3-6(13-2)4-8(9)12/h3-4,11-12H,1-2H3
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n/an/a 2.00E+5n/an/an/an/an/an/a



Beth Israel Deaconess Medical Center

Curated by ChEMBL


Assay Description
Inhibition of human KLF10 expressed in human HeLa cells assessed as reduction in transcriptional activity after 24 hrs by CACCC-responsive promoter d...


J Med Chem 58: 1466-78 (2015)


Article DOI: 10.1021/jm5018187
BindingDB Entry DOI: 10.7270/Q2WM1G3D
More data for this
Ligand-Target Pair