Compile Data Set for Download or QSAR

Found 26 hits of kd data for polymerid = 50006938,8689,8690   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 [1-118,T47W] (Homo sapiens (Human))	BDBM207976 (N-Methyl-3,5-di(4-chlorobenzyl)-4-(6-chloro-1H-ind...) Show SMILES CN1C(=O)C(Cc2ccc(Cl)cc2)=C(c2c[nH]c3cc(Cl)ccc23)C1(O)Cc1ccc(Cl)cc1 |t:13| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	500	n/a	n/a	n/a	7.4	25
Jagiellonian University					Assay Description MST (NanoTemper Technologies GmbH) was used to determine the binding affinities between Mdm2 (residues 1−118 T47W; 500 nM) and inhibitors. T47W...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair				3D Structure (crystal)
E3 ubiquitin-protein ligase Mdm2 [1-118] (Homo sapiens (Human))	BDBM207976 (N-Methyl-3,5-di(4-chlorobenzyl)-4-(6-chloro-1H-ind...) Show SMILES CN1C(=O)C(Cc2ccc(Cl)cc2)=C(c2c[nH]c3cc(Cl)ccc23)C1(O)Cc1ccc(Cl)cc1 |t:13| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	<1.00E+3	n/a	n/a	n/a	7.4	15
Jagiellonian University					Assay Description Uniform 15N isotope labeling was achieved by expression of the protein in the M9 minimal media containing 15NH4Cl as the sole nitrogen source. The fi...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair				3D Structure (crystal)
E3 ubiquitin-protein ligase Mdm2 [1-118] (Homo sapiens (Human))	BDBM207984 (3,5-Di(4-chlorobenzyl)-4-(6-chloro-1H-indol-3-yl)-...) Show SMILES OC1(Cc2ccc(Cl)cc2)OC(=O)C(Cc2ccc(Cl)cc2)=C1c1c[nH]c2cc(Cl)ccc12 |c:23| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	<1.00E+3	n/a	n/a	n/a	7.4	15
Jagiellonian University					Assay Description Uniform 15N isotope labeling was achieved by expression of the protein in the M9 minimal media containing 15NH4Cl as the sole nitrogen source. The fi...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair				3D Structure (crystal)
E3 ubiquitin-protein ligase Mdm2 [1-118,T47W] (Homo sapiens (Human))	BDBM207988 (5-(4-Chlorobenzyl)-4-(6-chloro-1H-indol-3-yl)-3-(4...) Show SMILES OC1(Cc2ccc(Cl)cc2)OC(=O)C(=C1c1c[nH]c2cc(Cl)ccc12)c1ccc(Cl)cc1 |c:14| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	7.4	25
Jagiellonian University					Assay Description MST (NanoTemper Technologies GmbH) was used to determine the binding affinities between Mdm2 (residues 1−118 T47W; 500 nM) and inhibitors. T47W...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118,T47W] (Homo sapiens (Human))	BDBM207985 (4,5-di(4-chlorobenzyl)-3-(6-chloro-1H-indol-3-yl)-...) Show SMILES OC1(Cc2ccc(Cl)cc2)OC(=O)C(=C1Cc1ccc(Cl)cc1)c1c[nH]c2cc(Cl)ccc12 |c:14| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	7.4	25
Jagiellonian University					Assay Description MST (NanoTemper Technologies GmbH) was used to determine the binding affinities between Mdm2 (residues 1−118 T47W; 500 nM) and inhibitors. T47W...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118,T47W] (Homo sapiens (Human))	BDBM207983 (N-(4-Chlorobenzyl)-3-(6-chloro-1H-indol-3-yl)-4-(4...) Show SMILES OC1N(Cc2ccc(Cl)cc2)C(=O)C(=C1c1ccc(Cl)cc1)c1c[nH]c2cc(Cl)ccc12 |c:14| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	7.4	25
Jagiellonian University					Assay Description MST (NanoTemper Technologies GmbH) was used to determine the binding affinities between Mdm2 (residues 1−118 T47W; 500 nM) and inhibitors. T47W...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118,T47W] (Homo sapiens (Human))	BDBM207984 (3,5-Di(4-chlorobenzyl)-4-(6-chloro-1H-indol-3-yl)-...) Show SMILES OC1(Cc2ccc(Cl)cc2)OC(=O)C(Cc2ccc(Cl)cc2)=C1c1c[nH]c2cc(Cl)ccc12 |c:23| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	7.4	25
Jagiellonian University					Assay Description MST (NanoTemper Technologies GmbH) was used to determine the binding affinities between Mdm2 (residues 1−118 T47W; 500 nM) and inhibitors. T47W...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair				3D Structure (crystal)
E3 ubiquitin-protein ligase Mdm2 [1-118,T47W] (Homo sapiens (Human))	BDBM207989 (5-(4-chlorobenzyl)-3-(6-chloro-1H-indol-3-yl)-4-(4...) Show SMILES OC1(Cc2ccc(Cl)cc2)OC(=O)C(=C1c1ccc(Cl)cc1)c1c[nH]c2cc(Cl)ccc12 |c:14| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.00E+3	n/a	n/a	n/a	7.4	25
Jagiellonian University					Assay Description MST (NanoTemper Technologies GmbH) was used to determine the binding affinities between Mdm2 (residues 1−118 T47W; 500 nM) and inhibitors. T47W...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118] (Homo sapiens (Human))	BDBM207986 (3-(4-Chlorobenzyl)-4-(6-chloro-1H-indol-3-yl)-5-(4...) Show SMILES OC1(Cc2ccc(F)cc2)OC(=O)C(Cc2ccc(Cl)cc2)=C1c1c[nH]c2cc(Cl)ccc12 |c:23| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.80E+4	n/a	n/a	n/a	7.4	15
Jagiellonian University					Assay Description Uniform 15N isotope labeling was achieved by expression of the protein in the M9 minimal media containing 15NH4Cl as the sole nitrogen source. The fi...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118,T47W] (Homo sapiens (Human))	BDBM207978 (N-Methyl-5-(4-chlorobenzyl)-4-(6-chloro-1H-indol-3...) Show SMILES CN1C(=O)C(=C(c2c[nH]c3cc(Cl)ccc23)C1(O)Cc1ccc(Cl)cc1)c1ccc(Cl)cc1 |t:4| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.87E+4	n/a	n/a	n/a	7.4	25
Jagiellonian University					Assay Description MST (NanoTemper Technologies GmbH) was used to determine the binding affinities between Mdm2 (residues 1−118 T47W; 500 nM) and inhibitors. T47W...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118,T47W] (Homo sapiens (Human))	BDBM207982 (N-(4-chlorobenzyl)-4-(6-chloro-1H-indol-3-yl)- 3-(...) Show SMILES OC1N(Cc2ccc(Cl)cc2)C(=O)C(=C1c1c[nH]c2cc(Cl)ccc12)c1ccc(Cl)cc1 |c:14| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.44E+4	n/a	n/a	n/a	7.4	25
Jagiellonian University					Assay Description MST (NanoTemper Technologies GmbH) was used to determine the binding affinities between Mdm2 (residues 1−118 T47W; 500 nM) and inhibitors. T47W...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118,T47W] (Homo sapiens (Human))	BDBM207987 (4-(4-chlorobenzyl)-3-(6-chloro-1H-indol-3-yl)-5-(4...) Show SMILES OC1(Cc2ccc(F)cc2)OC(=O)C(=C1Cc1ccc(Cl)cc1)c1c[nH]c2cc(Cl)ccc12 |c:14| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.60E+4	n/a	n/a	n/a	7.4	25
Jagiellonian University					Assay Description MST (NanoTemper Technologies GmbH) was used to determine the binding affinities between Mdm2 (residues 1−118 T47W; 500 nM) and inhibitors. T47W...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118,T47W] (Homo sapiens (Human))	BDBM207979 (N-methyl-5-(4-chlorobenzyl)-3-(6-chloro-1H-indol-3...) Show SMILES CN1C(=O)C(=C(c2ccc(Cl)cc2)C1(O)Cc1ccc(Cl)cc1)c1c[nH]c2cc(Cl)ccc12 |t:4| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.77E+4	n/a	n/a	n/a	7.4	25
Jagiellonian University					Assay Description MST (NanoTemper Technologies GmbH) was used to determine the binding affinities between Mdm2 (residues 1−118 T47W; 500 nM) and inhibitors. T47W...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118,T47W] (Homo sapiens (Human))	BDBM207986 (3-(4-Chlorobenzyl)-4-(6-chloro-1H-indol-3-yl)-5-(4...) Show SMILES OC1(Cc2ccc(F)cc2)OC(=O)C(Cc2ccc(Cl)cc2)=C1c1c[nH]c2cc(Cl)ccc12 |c:23| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.87E+4	n/a	n/a	n/a	7.4	25
Jagiellonian University					Assay Description MST (NanoTemper Technologies GmbH) was used to determine the binding affinities between Mdm2 (residues 1−118 T47W; 500 nM) and inhibitors. T47W...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118,T47W] (Homo sapiens (Human))	BDBM207981 (N-methyl-5-(4-chlorobenzyl)-3-(6-chloro-1-methyl-1...) Show SMILES CN1C(=O)C(=C(c2ccc(Cl)cc2)C1(O)Cc1ccc(Cl)cc1)c1cn(C)c2cc(Cl)ccc12 |t:4| Show InChI InChI=1S/C27H21Cl3N2O2/c1-31-15-22(21-12-11-20(30)13-23(21)31)24-25(17-5-9-19(29)10-6-17)27(34,32(2)26(24)33)14-16-3-7-18(28)8-4-16/h3-13,15,34H,14H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	3.04E+4	n/a	n/a	n/a	7.4	25
Jagiellonian University					Assay Description MST (NanoTemper Technologies GmbH) was used to determine the binding affinities between Mdm2 (residues 1−118 T47W; 500 nM) and inhibitors. T47W...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118] (Homo sapiens (Human))	BDBM207983 (N-(4-Chlorobenzyl)-3-(6-chloro-1H-indol-3-yl)-4-(4...) Show SMILES OC1N(Cc2ccc(Cl)cc2)C(=O)C(=C1c1ccc(Cl)cc1)c1c[nH]c2cc(Cl)ccc12 |c:14| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.00E+4	n/a	n/a	n/a	7.4	15
Jagiellonian University					Assay Description Uniform 15N isotope labeling was achieved by expression of the protein in the M9 minimal media containing 15NH4Cl as the sole nitrogen source. The fi...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118,T47W] (Homo sapiens (Human))	BDBM207980 (N-Methyl-5-(4-chlorobenzyl)-4-(6-chloro-1-methyl-1...) Show SMILES CN1C(=O)C(=C(c2cn(C)c3cc(Cl)ccc23)C1(O)Cc1ccc(Cl)cc1)c1ccc(Cl)cc1 |t:4| Show InChI InChI=1S/C27H21Cl3N2O2/c1-31-15-22(21-12-11-20(30)13-23(21)31)25-24(17-5-9-19(29)10-6-17)26(33)32(2)27(25,34)14-16-3-7-18(28)8-4-16/h3-13,15,34H,14H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	4.05E+4	n/a	n/a	n/a	7.4	25
Jagiellonian University					Assay Description MST (NanoTemper Technologies GmbH) was used to determine the binding affinities between Mdm2 (residues 1−118 T47W; 500 nM) and inhibitors. T47W...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118] (Homo sapiens (Human))	BDBM207978 (N-Methyl-5-(4-chlorobenzyl)-4-(6-chloro-1H-indol-3...) Show SMILES CN1C(=O)C(=C(c2c[nH]c3cc(Cl)ccc23)C1(O)Cc1ccc(Cl)cc1)c1ccc(Cl)cc1 |t:4| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.10E+4	n/a	n/a	n/a	7.4	15
Jagiellonian University					Assay Description Uniform 15N isotope labeling was achieved by expression of the protein in the M9 minimal media containing 15NH4Cl as the sole nitrogen source. The fi...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118] (Homo sapiens (Human))	BDBM207977 (N-methyl-4,5-di(4-chlorobenzyl)-3-(6-chloro-1H-ind...) Show SMILES CN1C(=O)C(=C(Cc2ccc(Cl)cc2)C1(O)Cc1ccc(Cl)cc1)c1c[nH]c2cc(Cl)ccc12 |t:4| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.60E+4	n/a	n/a	n/a	7.4	15
Jagiellonian University					Assay Description Uniform 15N isotope labeling was achieved by expression of the protein in the M9 minimal media containing 15NH4Cl as the sole nitrogen source. The fi...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118] (Homo sapiens (Human))	BDBM207988 (5-(4-Chlorobenzyl)-4-(6-chloro-1H-indol-3-yl)-3-(4...) Show SMILES OC1(Cc2ccc(Cl)cc2)OC(=O)C(=C1c1c[nH]c2cc(Cl)ccc12)c1ccc(Cl)cc1 |c:14| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	6.00E+4	n/a	n/a	n/a	7.4	15
Jagiellonian University					Assay Description Uniform 15N isotope labeling was achieved by expression of the protein in the M9 minimal media containing 15NH4Cl as the sole nitrogen source. The fi...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118] (Homo sapiens (Human))	BDBM207989 (5-(4-chlorobenzyl)-3-(6-chloro-1H-indol-3-yl)-4-(4...) Show SMILES OC1(Cc2ccc(Cl)cc2)OC(=O)C(=C1c1ccc(Cl)cc1)c1c[nH]c2cc(Cl)ccc12 |c:14| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	6.80E+4	n/a	n/a	n/a	7.4	15
Jagiellonian University					Assay Description Uniform 15N isotope labeling was achieved by expression of the protein in the M9 minimal media containing 15NH4Cl as the sole nitrogen source. The fi...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118] (Homo sapiens (Human))	BDBM207985 (4,5-di(4-chlorobenzyl)-3-(6-chloro-1H-indol-3-yl)-...) Show SMILES OC1(Cc2ccc(Cl)cc2)OC(=O)C(=C1Cc1ccc(Cl)cc1)c1c[nH]c2cc(Cl)ccc12 |c:14| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	8.60E+4	n/a	n/a	n/a	7.4	15
Jagiellonian University					Assay Description Uniform 15N isotope labeling was achieved by expression of the protein in the M9 minimal media containing 15NH4Cl as the sole nitrogen source. The fi...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118] (Homo sapiens (Human))	BDBM207982 (N-(4-chlorobenzyl)-4-(6-chloro-1H-indol-3-yl)- 3-(...) Show SMILES OC1N(Cc2ccc(Cl)cc2)C(=O)C(=C1c1c[nH]c2cc(Cl)ccc12)c1ccc(Cl)cc1 |c:14| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.64E+5	n/a	n/a	n/a	7.4	15
Jagiellonian University					Assay Description Uniform 15N isotope labeling was achieved by expression of the protein in the M9 minimal media containing 15NH4Cl as the sole nitrogen source. The fi...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118] (Homo sapiens (Human))	BDBM207979 (N-methyl-5-(4-chlorobenzyl)-3-(6-chloro-1H-indol-3...) Show SMILES CN1C(=O)C(=C(c2ccc(Cl)cc2)C1(O)Cc1ccc(Cl)cc1)c1c[nH]c2cc(Cl)ccc12 |t:4| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	1.92E+5	n/a	n/a	n/a	7.4	15
Jagiellonian University					Assay Description Uniform 15N isotope labeling was achieved by expression of the protein in the M9 minimal media containing 15NH4Cl as the sole nitrogen source. The fi...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118] (Homo sapiens (Human))	BDBM207981 (N-methyl-5-(4-chlorobenzyl)-3-(6-chloro-1-methyl-1...) Show SMILES CN1C(=O)C(=C(c2ccc(Cl)cc2)C1(O)Cc1ccc(Cl)cc1)c1cn(C)c2cc(Cl)ccc12 |t:4| Show InChI InChI=1S/C27H21Cl3N2O2/c1-31-15-22(21-12-11-20(30)13-23(21)31)24-25(17-5-9-19(29)10-6-17)27(34,32(2)26(24)33)14-16-3-7-18(28)8-4-16/h3-13,15,34H,14H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.46E+5	n/a	n/a	n/a	7.4	15
Jagiellonian University					Assay Description Uniform 15N isotope labeling was achieved by expression of the protein in the M9 minimal media containing 15NH4Cl as the sole nitrogen source. The fi...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 [1-118] (Homo sapiens (Human))	BDBM207980 (N-Methyl-5-(4-chlorobenzyl)-4-(6-chloro-1-methyl-1...) Show SMILES CN1C(=O)C(=C(c2cn(C)c3cc(Cl)ccc23)C1(O)Cc1ccc(Cl)cc1)c1ccc(Cl)cc1 |t:4| Show InChI InChI=1S/C27H21Cl3N2O2/c1-31-15-22(21-12-11-20(30)13-23(21)31)25-24(17-5-9-19(29)10-6-17)26(33)32(2)27(25,34)14-16-3-7-18(28)8-4-16/h3-13,15,34H,14H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	3.65E+5	n/a	n/a	n/a	7.4	15
Jagiellonian University					Assay Description Uniform 15N isotope labeling was achieved by expression of the protein in the M9 minimal media containing 15NH4Cl as the sole nitrogen source. The fi...				ACS Chem Biol 11: 3310-3318 (2016) Article DOI: 10.1021/acschembio.6b00596 BindingDB Entry DOI: 10.7270/Q2K35SH2
					More data for this Ligand-Target Pair