Compile Data Set for Download or QSAR

Found 56 hits of ic50 data for polymerid = 50007016   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tau-tubulin kinase 2 (Homo sapiens (Human))	CHEMBL5283456 Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	CHEMBL5280210 Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602886 (CHEMBL5182036) Show SMILES CC[C@@](C)(O)C#Cc1cc2n(ccc2cn1)-c1cc(OC)nc(N)n1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	CHEMBL5273263 Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602885 (CHEMBL5193906) Show SMILES CC1(N)CCN(Cc2ccn3ncnc(Nc4cc(O)cc(Br)c4)c23)CC1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50506660 (CHEMBL4528881) Show SMILES CC1(N)CCC(CC1)Nc1ccn2ncnc(Nc3cc(O)cc(Br)c3)c12 Show InChI InChI=1S/C19H23BrN6O/c1-19(21)5-2-13(3-6-19)24-16-4-7-26-17(16)18(22-11-23-26)25-14-8-12(20)9-15(27)10-14/h4,7-11,13,24,27H,2-3,5-6,21H2,1H3,(H,22,23,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Centro de Investigaciones Biol�gicas-CSIC Curated by ChEMBL					Assay Description Inhibition of TTBK2 (unknown origin)				Eur J Med Chem 161: 39-47 (2019) Article DOI: 10.1016/j.ejmech.2018.10.030 BindingDB Entry DOI: 10.7270/Q2V98CC0
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602917 (CHEMBL5200069) Show SMILES Clc1ccccc1Oc1ccc(Nc2ncnc3[nH]ccc23)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602903 (CHEMBL5198544) Show SMILES N(c1ccc(Oc2ccccc2)cc1)c1ncnc2[nH]ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	850	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602907 (CHEMBL5193488) Show SMILES COc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	970	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602926 (CHEMBL5200160 | US11814388, Compound 9) Show SMILES C(Oc1ccc(Nc2ncnc3[nH]ccc23)cc1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602909 (CHEMBL5197789) Show SMILES Brc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602910 (CHEMBL5209196) Show SMILES [O-][N+](=O)c1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602900 (CHEMBL5185704 | US11814388, Compound 3) Show SMILES COc1ccc(Nc2ncnc3[nH]ccc23)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602899 (CHEMBL5207783) Show SMILES N(c1ccccc1)c1ncnc2[nH]ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602933 (CHEMBL5178462) Show SMILES Cc1ccc(Cn2cc(COc3ccc(Nc4ncnc5[nH]ccc45)cc3)nn2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602931 (CHEMBL5197012) Show SMILES Clc1cccc(Cn2cc(COc3ccc(Nc4ncnc5[nH]ccc45)cc3)nn2)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602906 (CHEMBL5187459) Show SMILES N#Cc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602932 (CHEMBL5178965) Show SMILES C(Cn1cc(COc2ccc(Nc3ncnc4[nH]ccc34)cc2)nn1)c1ccccc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.61E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602920 (CHEMBL5187125) Show SMILES Nc1nc(Nc2ccc(Oc3ccc(Cl)cc3)cc2)c2cc[nH]c2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602930 (CHEMBL5181249) Show SMILES Clc1ccccc1Cn1cc(COc2ccc(Nc3ncnc4[nH]ccc34)cc2)nn1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602929 (CHEMBL5193034) Show SMILES Clc1ccc(Cn2cc(COc3ccc(Nc4ncnc5[nH]ccc45)cc3)nn2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602905 (CHEMBL5208565) Show SMILES Fc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602922 (CHEMBL5184336) Show SMILES Nc1nc(Nc2ccc(Oc3cccc(Cl)c3)cc2)c2cc[nH]c2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602923 (CHEMBL5178871) Show SMILES Nc1nc(Nc2ccc(Oc3cccc(c3)C(F)(F)F)cc2)c2cc[nH]c2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50506661 (CHEMBL4517951) Show SMILES COC(=O)c1cc(Nc2ncnc3[nH]ccc23)ccc1Br Show InChI InChI=1S/C14H11BrN4O2/c1-21-14(20)10-6-8(2-3-11(10)15)19-13-9-4-5-16-12(9)17-7-18-13/h2-7H,1H3,(H2,16,17,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602904 (CHEMBL5204869) Show SMILES Clc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	4.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602921 (CHEMBL5180098) Show SMILES Nc1nc(Nc2ccc(Oc3ccc(cc3)C(F)(F)F)cc2)c2cc[nH]c2n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602911 (CHEMBL5171328) Show SMILES Nc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602925 (CHEMBL5188513) Show SMILES Nc1ccc(Sc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602928 (CHEMBL5209161) Show SMILES Fc1ccc(cc1)C(=O)c1ccc(Nc2ncnc3[nH]ccc23)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602898 (CHEMBL5171736) Show SMILES C1CN(CCO1)c1cccc(Nc2ncnc3[nH]ccc23)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602919 (CHEMBL5169390) Show SMILES Clc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1Cl Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602934 (CHEMBL5206548) Show SMILES N(c1ccc(Oc2cccnc2)cc1)c1ncnc2[nH]ccc12 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.05E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602913 (CHEMBL5207918) Show SMILES Cc1cccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602888 (CHEMBL5204443) Show SMILES Oc1cccc(Nc2ncnc3[nH]ccc23)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602916 (CHEMBL5196033) Show SMILES COc1cccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602889 (CHEMBL5186693) Show SMILES Oc1ccc(Nc2ncnc3[nH]ccc23)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602896 (CHEMBL5182006) Show SMILES C1Oc2cccc(Nc3ncnc4[nH]ccc34)c2O1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602901 (CHEMBL5202436) Show SMILES CC(C)Oc1ccc(Nc2ncnc3[nH]ccc23)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602912 (CHEMBL5179559) Show SMILES Cc1ccc(Oc2ccc(Nc3ncnc4[nH]ccc34)cc2)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50328192 (CHEMBL1257781 | N-(4-(Trifluoromethoxy)phenyl)-7H-...) Show SMILES FC(F)(F)Oc1ccc(Nc2ncnc3[nH]ccc23)cc1 Show InChI InChI=1S/C13H9F3N4O/c14-13(15,16)21-9-3-1-8(2-4-9)20-12-10-5-6-17-11(10)18-7-19-12/h1-7H,(H2,17,18,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602897 (CHEMBL5209114) Show SMILES CC(=O)c1ccc(Nc2ncnc3[nH]ccc23)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50044784 (CHEBI:79090 | SB-202190 | US10865384, Compound SB2...) Show SMILES Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1 Show InChI InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	9.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Inhibition of human TTBK2 using MBP as substrate by [gamma-33P]-ATP assay				Eur J Med Chem 161: 456-467 (2019) Article DOI: 10.1016/j.ejmech.2018.10.052 BindingDB Entry DOI: 10.7270/Q2W380MT
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602918 (CHEMBL5193008) Show SMILES COc1ccccc1Oc1ccc(Nc2ncnc3[nH]ccc23)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50519662 (CHEMBL4438748) Show SMILES CN(C)c1ccc(cc1)C(=O)Nc1cccc(NC(=O)COc2ccc3c(c2)occc3=O)c1 Show InChI InChI=1S/C26H23N3O5/c1-29(2)20-8-6-17(7-9-20)26(32)28-19-5-3-4-18(14-19)27-25(31)16-34-21-10-11-22-23(30)12-13-33-24(22)15-21/h3-15H,16H2,1-2H3,(H,27,31)(H,28,32)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of recombinant human TTBK2 (1 to331 residues) using casein as substrate incubated for 40 mins in presence of [gamma33P]ATP by radiometric ...				J Med Chem 62: 10691-10710 (2019) Article DOI: 10.1021/acs.jmedchem.9b01143 BindingDB Entry DOI: 10.7270/Q2MC93FG
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50135286 (CHEMBL3745885) Show SMILES Cn1c2nc(Nc3ccc4[nH]ccc4c3)ncc2cc(c1=O)S(=O)(=O)c1ccc(F)cc1F Show InChI InChI=1S/C22H15F2N5O3S/c1-29-20-13(9-19(21(29)30)33(31,32)18-5-2-14(23)10-16(18)24)11-26-22(28-20)27-15-3-4-17-12(8-15)6-7-25-17/h2-11,25H,1H3,(H,26,27,28)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Icahn School of Medicine at Mount Sinai Curated by ChEMBL					Assay Description Inhibition of human TTBK2 using MBP substrate				Bioorg Med Chem 24: 521-44 (2016) Article DOI: 10.1016/j.bmc.2015.11.045 BindingDB Entry DOI: 10.7270/Q24Q7WT8
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602927 (CHEMBL5193908) Show SMILES O=C(c1ccccc1)c1ccc(Nc2ncnc3[nH]ccc23)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602902 (CHEMBL5208571) Show SMILES CCOc1ccc(Nc2ncnc3[nH]ccc23)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602894 (CHEMBL5186604) Show SMILES Clc1cccc(Nc2ncnc3[nH]ccc23)c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair
Tau-tubulin kinase 2 (Homo sapiens (Human))	BDBM50602890 (CHEMBL5198629) Show SMILES C1CN(CCO1)c1ccc(Nc2ncnc3[nH]ccc23)cc1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01942 BindingDB Entry DOI: 10.7270/Q2R215GV
					More data for this Ligand-Target Pair

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