Compile Data Set for Download or QSAR

Found 77 hits of ic50 for UniProtKB: Q9NR63   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50253810 (CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4-triazol-1...) Show SMILES CCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1 Show InChI InChI=1S/C21H23N5S/c1-3-15(4-2)20(26-14-22-13-23-26)16-9-11-17(12-10-16)24-21-25-18-7-5-6-8-19(18)27-21/h5-15,20H,3-4H2,1-2H3,(H,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	US Patent	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
University of Washington at Seattle					Assay Description Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...				J Med Chem 52: 1864-72 (2009) BindingDB Entry DOI: 10.7270/Q2FN18J2
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50253810 (CHEMBL459505 | N-(4-(2-ethyl-1-(1H-1,2,4-triazol-1...) Show SMILES CCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1 Show InChI InChI=1S/C21H23N5S/c1-3-15(4-2)20(26-14-22-13-23-26)16-9-11-17(12-10-16)24-21-25-18-7-5-6-8-19(18)27-21/h5-15,20H,3-4H2,1-2H3,(H,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM393281 (US9963439, R116010) Show SMILES CC(C(c1ccc(Nc2nc3ccccc3s2)cc1)n1ccnc1)N(C)C Show InChI InChI=1S/C21H23N5S/c1-15(25(2)3)20(26-13-12-22-14-26)16-8-10-17(11-9-16)23-21-24-18-6-4-5-7-19(18)27-21/h4-15,20H,1-3H3,(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
University of Washington at Seattle					Assay Description Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...				J Med Chem 52: 1864-72 (2009) BindingDB Entry DOI: 10.7270/Q2FN18J2
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157605 (Liarozole | Liazal | R-75251 | US9963439, Liarozol...) Show SMILES Clc1cccc(c1)C(c1ccc2[nH]cnc2c1)n1ccnc1 Show InChI InChI=1S/C17H13ClN4/c18-14-3-1-2-12(8-14)17(22-7-6-19-11-22)13-4-5-15-16(9-13)21-10-20-15/h1-11,17H,(H,20,21)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Washington at Seattle					Assay Description Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...				J Med Chem 52: 1864-72 (2009) BindingDB Entry DOI: 10.7270/Q2FN18J2
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157605 (Liarozole | Liazal | R-75251 | US9963439, Liarozol...) Show SMILES Clc1cccc(c1)C(c1ccc2[nH]cnc2c1)n1ccnc1 Show InChI InChI=1S/C17H13ClN4/c18-14-3-1-2-12(8-14)17(22-7-6-19-11-22)13-4-5-15-16(9-13)21-10-20-15/h1-11,17H,(H,20,21)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM151585 (US11739089, Compound Ketoconazole | US8987315, Ket...) Show SMILES CC(=O)N1CCN(CC1)c1ccc(OCC2COC(Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1 Show InChI InChI=1S/C26H28Cl2N4O4/c1-19(33)31-10-12-32(13-11-31)21-3-5-22(6-4-21)34-15-23-16-35-26(36-23,17-30-9-8-29-18-30)24-7-2-20(27)14-25(24)28/h2-9,14,18,23H,10-13,15-17H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
University of Washington at Seattle					Assay Description Eighteen compounds were tested as potential inhibitors of CYP26A1 and CYP26B1. The formation of 9-cis-4-OH-RA metabolite was monitored and the percen...				J Med Chem 52: 1864-72 (2009) BindingDB Entry DOI: 10.7270/Q2FN18J2
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM557292 (US11358933, Compound 026) Show SMILES CC(C)(C)c1cccc(c1)-c1cc2cc(\C=C\C(O)=O)ccc2[nH]1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description CYP26 inhibitory activities of various compounds.				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13XJ
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476235 (US10874634, Cmpd No. 17 | US11364220, Compound 17) Show SMILES CCC(CC)(C(O)=O)c1ccc(NS(=O)(=O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1 Show InChI InChI=1S/C26H35NO4S/c1-7-26(8-2,23(28)29)18-9-11-19(12-10-18)27-32(30,31)20-13-14-21-22(17-20)25(5,6)16-15-24(21,3)4/h9-14,17,27H,7-8,15-16H2,1-6H3,(H,28,29)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QN6B03
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476235 (US10874634, Cmpd No. 17 | US11364220, Compound 17) Show SMILES CCC(CC)(C(O)=O)c1ccc(NS(=O)(=O)c2ccc3c(c2)C(C)(C)CCC3(C)C)cc1 Show InChI InChI=1S/C26H35NO4S/c1-7-26(8-2,23(28)29)18-9-11-19(12-10-18)27-32(30,31)20-13-14-21-22(17-20)25(5,6)16-15-24(21,3)4/h9-14,17,27H,7-8,15-16H2,1-6H3,(H,28,29)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Queen''s University at Kingston US Patent					Assay Description CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...				US Patent US10874634 (2020) BindingDB Entry DOI: 10.7270/Q2Q52SP3
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM557299 (US11358933, Compound 034) Show SMILES Cc1ccc(cc1-c1cc2cc(\C=C\C(O)=O)ccc2[nH]1)C(C)(C)C Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description CYP26 inhibitory activities of various compounds.				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13XJ
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM31886 (CD564 | CHEMBL309282) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)c1ccc2cc(ccc2c1)C(O)=O Show InChI InChI=1S/C26H26O3/c1-25(2)11-12-26(3,4)22-15-19(9-10-21(22)25)23(27)18-7-5-17-14-20(24(28)29)8-6-16(17)13-18/h5-10,13-15H,11-12H2,1-4H3,(H,28,29)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476228 (US10874634, Cmpd No. 10 | US11364220, Compound 10) Show SMILES Cc1cc2c(c(C)c1C(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C25H31NO3/c1-15-13-19-22(25(5,6)12-11-24(19,3)4)16(2)21(15)23(29)26-18-9-7-17(8-10-18)14-20(27)28/h7-10,13H,11-12,14H2,1-6H3,(H,26,29)(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Queen''s University at Kingston US Patent					Assay Description CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...				US Patent US10874634 (2020) BindingDB Entry DOI: 10.7270/Q2Q52SP3
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476228 (US10874634, Cmpd No. 10 | US11364220, Compound 10) Show SMILES Cc1cc2c(c(C)c1C(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C25H31NO3/c1-15-13-19-22(25(5,6)12-11-24(19,3)4)16(2)21(15)23(29)26-18-9-7-17(8-10-18)14-20(27)28/h7-10,13H,11-12,14H2,1-6H3,(H,26,29)(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QN6B03
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157722 (CHEMBL3787323) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1(SCCS1)c1ccc(CCC(O)=O)cc1 Show InChI InChI=1S/C26H32O2S2/c1-24(2)13-14-25(3,4)22-17-20(10-11-21(22)24)26(29-15-16-30-26)19-8-5-18(6-9-19)7-12-23(27)28/h5-6,8-11,17H,7,12-16H2,1-4H3,(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	680	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157724 (CHEMBL3787564 | US9963439, Compound B) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)COc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H26O4/c1-22(2)11-12-23(3,4)19-13-16(7-10-18(19)22)20(24)14-27-17-8-5-15(6-9-17)21(25)26/h5-10,13H,11-12,14H2,1-4H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	930	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157727 (CHEMBL3786184) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1(SCCS1)c1ccc2cc(ccc2c1)C(O)=O Show InChI InChI=1S/C28H30O2S2/c1-26(2)11-12-27(3,4)24-17-22(9-10-23(24)26)28(31-13-14-32-28)21-8-7-18-15-20(25(29)30)6-5-19(18)16-21/h5-10,15-17H,11-14H2,1-4H3,(H,29,30)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157721 (CHEMBL3786620) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1(OCCO1)c1ccc2cc(ccc2c1)C(O)=O Show InChI InChI=1S/C28H30O4/c1-26(2)11-12-27(3,4)24-17-22(9-10-23(24)26)28(31-13-14-32-28)21-8-7-18-15-20(25(29)30)6-5-19(18)16-21/h5-10,15-17H,11-14H2,1-4H3,(H,29,30)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50033067 (4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1(SCCS1)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H28O2S2/c1-22(2)11-12-23(3,4)20-15-18(9-10-19(20)22)24(27-13-14-28-24)17-7-5-16(6-8-17)21(25)26/h5-10,15H,11-14H2,1-4H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157729 (CHEMBL3787691) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C(\COc1ccc(cc1)C(O)=O)=N\O Show InChI InChI=1S/C23H27NO4/c1-22(2)11-12-23(3,4)19-13-16(7-10-18(19)22)20(24-27)14-28-17-8-5-15(6-9-17)21(25)26/h5-10,13,27H,11-12,14H2,1-4H3,(H,25,26)/b24-20+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157731 (CHEMBL3785511 | US9963439, Compound C) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C(O)COc1ccc(cc1)C(O)=O Show InChI InChI=1S/C23H28O4/c1-22(2)11-12-23(3,4)19-13-16(7-10-18(19)22)20(24)14-27-17-8-5-15(6-9-17)21(25)26/h5-10,13,20,24H,11-12,14H2,1-4H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157604 (CHEMBL3786324) Show SMILES CC1(C)CCC(C)(C)c2cc(Cc3ccc(CCC(O)=O)cc3)ccc12 Show InChI InChI=1S/C24H30O2/c1-23(2)13-14-24(3,4)21-16-19(9-11-20(21)23)15-18-7-5-17(6-8-18)10-12-22(25)26/h5-9,11,16H,10,12-15H2,1-4H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476180 (US10874634, Cmpd No. 02 | US11364220, Compound 02) Show SMILES Cc1cc2c(cc1C(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H29NO3/c1-15-12-19-20(24(4,5)11-10-23(19,2)3)14-18(15)22(28)25-17-8-6-16(7-9-17)13-21(26)27/h6-9,12,14H,10-11,13H2,1-5H3,(H,25,28)(H,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	2.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Queen''s University at Kingston US Patent					Assay Description CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...				US Patent US10874634 (2020) BindingDB Entry DOI: 10.7270/Q2Q52SP3
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476180 (US10874634, Cmpd No. 02 | US11364220, Compound 02) Show SMILES Cc1cc2c(cc1C(=O)Nc1ccc(CC(O)=O)cc1)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H29NO3/c1-15-12-19-20(24(4,5)11-10-23(19,2)3)14-18(15)22(28)25-17-8-6-16(7-9-17)13-21(26)27/h6-9,12,14H,10-11,13H2,1-5H3,(H,25,28)(H,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	2.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QN6B03
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM557298 (US11358933, Compound 032) Show SMILES CC(C)(C)c1cccc(c1)-c1cc2cc(CC(O)=O)ccc2o1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description CYP26 inhibitory activities of various compounds.				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13XJ
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157718 (CHEMBL3785701) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1(SCCS1)c1ccc(\C=C\C(O)=O)cc1 Show InChI InChI=1S/C26H30O2S2/c1-24(2)13-14-25(3,4)22-17-20(10-11-21(22)24)26(29-15-16-30-26)19-8-5-18(6-9-19)7-12-23(27)28/h5-12,17H,13-16H2,1-4H3,(H,27,28)/b12-7+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157719 (CHEMBL3785624) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)c1ccc(CCC(O)=O)cc1 Show InChI InChI=1S/C24H28O3/c1-23(2)13-14-24(3,4)20-15-18(10-11-19(20)23)22(27)17-8-5-16(6-9-17)7-12-21(25)26/h5-6,8-11,15H,7,12-14H2,1-4H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157723 (CHEMBL3786927) Show SMILES CC1(C)CCC(C)(C)c2cc(Sc3cccc(CC(O)=O)c3)ccc12 Show InChI InChI=1S/C22H26O2S/c1-21(2)10-11-22(3,4)19-14-17(8-9-18(19)21)25-16-7-5-6-15(12-16)13-20(23)24/h5-9,12,14H,10-11,13H2,1-4H3,(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157726 (CHEMBL3786043) Show SMILES CC1(C)CCC(C)(C)c2cc(Sc3ccc(CC(O)=O)cc3)ccc12 Show InChI InChI=1S/C22H26O2S/c1-21(2)11-12-22(3,4)19-14-17(9-10-18(19)21)25-16-7-5-15(6-8-16)13-20(23)24/h5-10,14H,11-13H2,1-4H3,(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157608 (CHEMBL95949) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)c1ccc(\C=C\C(O)=O)cc1 Show InChI InChI=1S/C24H26O3/c1-23(2)13-14-24(3,4)20-15-18(10-11-19(20)23)22(27)17-8-5-16(6-9-17)7-12-21(25)26/h5-12,15H,13-14H2,1-4H3,(H,25,26)/b12-7+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157730 (CHEMBL3785557) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)S(=O)(=O)c1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C22H26O4S/c1-21(2)11-12-22(3,4)19-14-17(9-10-18(19)21)27(25,26)16-7-5-15(6-8-16)13-20(23)24/h5-10,14H,11-13H2,1-4H3,(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157728 (CHEMBL3785761) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)S(=O)(=O)c1cccc(CC(O)=O)c1 Show InChI InChI=1S/C22H26O4S/c1-21(2)10-11-22(3,4)19-14-17(8-9-18(19)21)27(25,26)16-7-5-6-15(12-16)13-20(23)24/h5-9,12,14H,10-11,13H2,1-4H3,(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50032675 (4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...) Show SMILES Cc1cc2c(cc1C(=C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157720 (CHEMBL3786340) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)S(=O)(=O)c1ccc(CCC(O)=O)cc1 Show InChI InChI=1S/C23H28O4S/c1-22(2)13-14-23(3,4)20-15-18(10-11-19(20)22)28(26,27)17-8-5-16(6-9-17)7-12-21(24)25/h5-6,8-11,15H,7,12-14H2,1-4H3,(H,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM557293 (US11358933, Compound 027) Show SMILES CC1(C)CC(C)(C)c2cc(cc(CC=C)c2O1)C(=O)Cc1ccc(CC(O)=O)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description CYP26 inhibitory activities of various compounds.				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13XJ
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476173 (US10874634, Cmpd No. 01 | US11364220, Compound 01) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)Nc1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C23H27NO3/c1-22(2)11-12-23(3,4)19-14-16(7-10-18(19)22)21(27)24-17-8-5-15(6-9-17)13-20(25)26/h5-10,14H,11-13H2,1-4H3,(H,24,27)(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	8.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QN6B03
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476173 (US10874634, Cmpd No. 01 | US11364220, Compound 01) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)Nc1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C23H27NO3/c1-22(2)11-12-23(3,4)19-14-16(7-10-18(19)22)21(27)24-17-8-5-15(6-9-17)13-20(25)26/h5-10,14H,11-13H2,1-4H3,(H,24,27)(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	8.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
Queen''s University at Kingston US Patent					Assay Description CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...				US Patent US10874634 (2020) BindingDB Entry DOI: 10.7270/Q2Q52SP3
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476236 (US10874634, Cmpd No. 18 | US11364220, Compound 18) Show SMILES CCC(CC)(C(O)=O)c1ccc(NS(=O)(=O)c2cc3c(cc2C)C(C)(C)CCC3(C)C)cc1 Show InChI InChI=1S/C27H37NO4S/c1-8-27(9-2,24(29)30)19-10-12-20(13-11-19)28-33(31,32)23-17-22-21(16-18(23)3)25(4,5)14-15-26(22,6)7/h10-13,16-17,28H,8-9,14-15H2,1-7H3,(H,29,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QN6B03
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476236 (US10874634, Cmpd No. 18 | US11364220, Compound 18) Show SMILES CCC(CC)(C(O)=O)c1ccc(NS(=O)(=O)c2cc3c(cc2C)C(C)(C)CCC3(C)C)cc1 Show InChI InChI=1S/C27H37NO4S/c1-8-27(9-2,24(29)30)19-10-12-20(13-11-19)28-33(31,32)23-17-22-21(16-18(23)3)25(4,5)14-15-26(22,6)7/h10-13,16-17,28H,8-9,14-15H2,1-7H3,(H,29,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
Queen''s University at Kingston US Patent					Assay Description CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...				US Patent US10874634 (2020) BindingDB Entry DOI: 10.7270/Q2Q52SP3
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157717 (CHEMBL3786581) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1(OCCO1)c1ccc(\C=C\C(O)=O)cc1 Show InChI InChI=1S/C26H30O4/c1-24(2)13-14-25(3,4)22-17-20(10-11-21(22)24)26(29-15-16-30-26)19-8-5-18(6-9-19)7-12-23(27)28/h5-12,17H,13-16H2,1-4H3,(H,27,28)/b12-7+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476222 (US10874634, Cmpd No. 05 | US11364220, Compound 05) Show SMILES CC1(C)CCOc2ccc(cc12)C(=O)Nc1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C20H21NO4/c1-20(2)9-10-25-17-8-5-14(12-16(17)20)19(24)21-15-6-3-13(4-7-15)11-18(22)23/h3-8,12H,9-11H2,1-2H3,(H,21,24)(H,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Queen''s University at Kingston US Patent					Assay Description CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...				US Patent US10874634 (2020) BindingDB Entry DOI: 10.7270/Q2Q52SP3
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476222 (US10874634, Cmpd No. 05 | US11364220, Compound 05) Show SMILES CC1(C)CCOc2ccc(cc12)C(=O)Nc1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C20H21NO4/c1-20(2)9-10-25-17-8-5-14(12-16(17)20)19(24)21-15-6-3-13(4-7-15)11-18(22)23/h3-8,12H,9-11H2,1-2H3,(H,21,24)(H,22,23)	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	1.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QN6B03
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476234 (US10874634, Cmpd No. 16 | US11364220, Compound 16) Show SMILES Cc1cc2c(cc1C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C26H33NO3/c1-16-14-20-21(25(4,5)13-12-24(20,2)3)15-19(16)22(28)27-18-10-8-17(9-11-18)26(6,7)23(29)30/h8-11,14-15H,12-13H2,1-7H3,(H,27,28)(H,29,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
Queen''s University at Kingston US Patent					Assay Description CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...				US Patent US10874634 (2020) BindingDB Entry DOI: 10.7270/Q2Q52SP3
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476234 (US10874634, Cmpd No. 16 | US11364220, Compound 16) Show SMILES Cc1cc2c(cc1C(=O)Nc1ccc(cc1)C(C)(C)C(O)=O)C(C)(C)CCC2(C)C Show InChI InChI=1S/C26H33NO3/c1-16-14-20-21(25(4,5)13-12-24(20,2)3)15-19(16)22(28)27-18-10-8-17(9-11-18)26(6,7)23(29)30/h8-11,14-15H,12-13H2,1-7H3,(H,27,28)(H,29,30)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QN6B03
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50033077 (4-[2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1(OCCO1)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C24H28O4/c1-22(2)11-12-23(3,4)20-15-18(9-10-19(20)22)24(27-13-14-28-24)17-7-5-16(6-8-17)21(25)26/h5-10,15H,11-14H2,1-4H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476226 (US10874634, Cmpd No. 09 | US11364220, Compound 09) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)S(=O)(=O)Nc1ccc(CC(O)=O)c(F)c1 Show InChI InChI=1S/C22H26FNO4S/c1-21(2)9-10-22(3,4)18-13-16(7-8-17(18)21)29(27,28)24-15-6-5-14(11-20(25)26)19(23)12-15/h5-8,12-13,24H,9-11H2,1-4H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description This retinoid activity assay measures the ability of test compounds to induce expression of a transiently transfected RA sensitive reporter construct...				Citation and Details BindingDB Entry DOI: 10.7270/Q2QN6B03
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476226 (US10874634, Cmpd No. 09 | US11364220, Compound 09) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)S(=O)(=O)Nc1ccc(CC(O)=O)c(F)c1 Show InChI InChI=1S/C22H26FNO4S/c1-21(2)9-10-22(3,4)18-13-16(7-8-17(18)21)29(27,28)24-15-6-5-14(11-20(25)26)19(23)12-15/h5-8,12-13,24H,9-11H2,1-4H3,(H,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
Queen''s University at Kingston US Patent					Assay Description CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...				US Patent US10874634 (2020) BindingDB Entry DOI: 10.7270/Q2Q52SP3
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM50157611 (CHEMBL3787627) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1(OCCO1)c1ccc(CCC(O)=O)cc1 Show InChI InChI=1S/C26H32O4/c1-24(2)13-14-25(3,4)22-17-20(10-11-21(22)24)26(29-15-16-30-26)19-8-5-18(6-9-19)7-12-23(27)28/h5-6,8-11,17H,7,12-16H2,1-4H3,(H,27,28)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
The University of Montana Curated by ChEMBL					Assay Description Inhibition of microsomal fraction of human CYP26B1 expressed in Sf9 cells using 9-cis-RA as substrate preincubated for 5 mins followed by NADPH addit...				J Med Chem 59: 2579-95 (2016) Article DOI: 10.1021/acs.jmedchem.5b01780 BindingDB Entry DOI: 10.7270/Q2J38VG8
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM557291 (US11358933, Compound 025) Show SMILES CC(C)(C)c1cccc(c1)C(=O)Cc1ccc(\C=C\C(O)=O)cc1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description CYP26 inhibitory activities of various compounds.				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13XJ
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM557297 (US11358933, Compound 031) Show SMILES CC(C)(C)c1cccc(c1)-c1cc2cc(\C=C\C(O)=O)ccc2o1 Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description CYP26 inhibitory activities of various compounds.				Citation and Details BindingDB Entry DOI: 10.7270/Q2CC13XJ
					More data for this Ligand-Target Pair
Cytochrome P450 26B1 (Homo sapiens (Human))	BDBM476217 (US10874634, Cmpd No. 04 | US11364220, Compound 04) Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)S(=O)(=O)Nc1ccc(CC(O)=O)cc1 Show InChI InChI=1S/C22H27NO4S/c1-21(2)11-12-22(3,4)19-14-17(9-10-18(19)21)28(26,27)23-16-7-5-15(6-8-16)13-20(24)25/h5-10,14,23H,11-13H2,1-4H3,(H,24,25)	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	n/a	n/a	1.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
Queen''s University at Kingston US Patent					Assay Description CYP26A1 or CYP26B1 stably transfected HeLa cells were maintained in Minimum Essential Medium (MEM) containing 10% fetal bovine serum (FBS) and 100 &#...				US Patent US10874634 (2020) BindingDB Entry DOI: 10.7270/Q2Q52SP3
					More data for this Ligand-Target Pair

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