Compile Data Set for Download or QSAR

Found 8 hits of ic50 data for polymerid = 50007104   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/nucleoside cotransporter 2 (Rattus norvegicus)	BDBM50172392 (CHEMBL3808747) Show SMILES OCCCCOc1cc(CNc2nc3ccccc3n2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)ccc1-c1ccccc1 |r| Show InChI InChI=1S/C29H33N3O6/c33-14-6-7-15-37-24-16-19(12-13-21(24)20-8-2-1-3-9-20)17-30-29-31-22-10-4-5-11-23(22)32(29)28-27(36)26(35)25(18-34)38-28/h1-5,8-13,16,25-28,33-36H,6-7,14-15,17-18H2,(H,30,31)/t25-,26-,27-,28-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of rat CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting an...				J Med Chem 59: 3719-31 (2016) Article DOI: 10.1021/acs.jmedchem.5b01884 BindingDB Entry DOI: 10.7270/Q2ZW1NT8
					More data for this Ligand-Target Pair
Sodium/nucleoside cotransporter 2 (Rattus norvegicus)	BDBM50172396 (CHEMBL3809613) Show SMILES Nc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NCc3ccc(c(OCCCCO)c3)-c3ccccc3)nc12 |r| Show InChI InChI=1S/C27H32N6O6/c28-24-21-25(31-15-30-24)33(26-23(37)22(36)20(14-35)39-26)27(32-21)29-13-16-8-9-18(17-6-2-1-3-7-17)19(12-16)38-11-5-4-10-34/h1-3,6-9,12,15,20,22-23,26,34-37H,4-5,10-11,13-14H2,(H,29,32)(H2,28,30,31)/t20-,22-,23-,26-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of rat CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting an...				J Med Chem 59: 3719-31 (2016) Article DOI: 10.1021/acs.jmedchem.5b01884 BindingDB Entry DOI: 10.7270/Q2ZW1NT8
					More data for this Ligand-Target Pair
Sodium/nucleoside cotransporter 2 (Rattus norvegicus)	BDBM50172397 (CHEMBL3809514) Show SMILES Nc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NCc3ccc(c(OCCCO)c3)-c3ccccc3)nc12 |r| Show InChI InChI=1S/C26H30N6O6/c27-23-20-24(30-14-29-23)32(25-22(36)21(35)19(13-34)38-25)26(31-20)28-12-15-7-8-17(16-5-2-1-3-6-16)18(11-15)37-10-4-9-33/h1-3,5-8,11,14,19,21-22,25,33-36H,4,9-10,12-13H2,(H,28,31)(H2,27,29,30)/t19-,21-,22-,25-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of rat CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting an...				J Med Chem 59: 3719-31 (2016) Article DOI: 10.1021/acs.jmedchem.5b01884 BindingDB Entry DOI: 10.7270/Q2ZW1NT8
					More data for this Ligand-Target Pair
Sodium/nucleoside cotransporter 2 (Rattus norvegicus)	BDBM50172394 (CHEMBL3809286) Show SMILES Nc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NCc3ccc(c(OCCCCCO)c3)-c3ccccc3)nc12 |r| Show InChI InChI=1S/C28H34N6O6/c29-25-22-26(32-16-31-25)34(27-24(38)23(37)21(15-36)40-27)28(33-22)30-14-17-9-10-19(18-7-3-1-4-8-18)20(13-17)39-12-6-2-5-11-35/h1,3-4,7-10,13,16,21,23-24,27,35-38H,2,5-6,11-12,14-15H2,(H,30,33)(H2,29,31,32)/t21-,23-,24-,27-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of rat CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting an...				J Med Chem 59: 3719-31 (2016) Article DOI: 10.1021/acs.jmedchem.5b01884 BindingDB Entry DOI: 10.7270/Q2ZW1NT8
					More data for this Ligand-Target Pair
Sodium/nucleoside cotransporter 2 (Rattus norvegicus)	BDBM50172411 (CHEMBL3809974) Show SMILES Nc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NCc3ccc(cc3)-c3cccnc3)nc12 |r| Show InChI InChI=1S/C22H23N7O4/c23-19-16-20(27-11-26-19)29(21-18(32)17(31)15(10-30)33-21)22(28-16)25-8-12-3-5-13(6-4-12)14-2-1-7-24-9-14/h1-7,9,11,15,17-18,21,30-32H,8,10H2,(H,25,28)(H2,23,26,27)/t15-,17-,18-,21-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of rat CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting an...				J Med Chem 59: 3719-31 (2016) Article DOI: 10.1021/acs.jmedchem.5b01884 BindingDB Entry DOI: 10.7270/Q2ZW1NT8
					More data for this Ligand-Target Pair
Sodium/nucleoside cotransporter 2 (Rattus norvegicus)	BDBM50172398 (CHEMBL3808498) Show SMILES Nc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NCc3ccc(c(OCCO)c3)-c3ccccc3)nc12 |r| Show InChI InChI=1S/C25H28N6O6/c26-22-19-23(29-13-28-22)31(24-21(35)20(34)18(12-33)37-24)25(30-19)27-11-14-6-7-16(15-4-2-1-3-5-15)17(10-14)36-9-8-32/h1-7,10,13,18,20-21,24,32-35H,8-9,11-12H2,(H,27,30)(H2,26,28,29)/t18-,20-,21-,24-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of rat CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting an...				J Med Chem 59: 3719-31 (2016) Article DOI: 10.1021/acs.jmedchem.5b01884 BindingDB Entry DOI: 10.7270/Q2ZW1NT8
					More data for this Ligand-Target Pair
Sodium/nucleoside cotransporter 2 (Rattus norvegicus)	BDBM50172399 (CHEMBL3808734) Show SMILES NC(=O)COc1cc(CNc2nc3c(N)ncnc3n2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)ccc1-c1ccccc1 |r| Show InChI InChI=1S/C25H27N7O6/c26-18(34)11-37-16-8-13(6-7-15(16)14-4-2-1-3-5-14)9-28-25-31-19-22(27)29-12-30-23(19)32(25)24-21(36)20(35)17(10-33)38-24/h1-8,12,17,20-21,24,33,35-36H,9-11H2,(H2,26,34)(H,28,31)(H2,27,29,30)/t17-,20-,21-,24-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of rat CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting an...				J Med Chem 59: 3719-31 (2016) Article DOI: 10.1021/acs.jmedchem.5b01884 BindingDB Entry DOI: 10.7270/Q2ZW1NT8
					More data for this Ligand-Target Pair
Sodium/nucleoside cotransporter 2 (Rattus norvegicus)	BDBM50172393 (CHEMBL3809118) Show SMILES OCCCCOc1cc(CNc2nc3c(nc[nH]c3=O)n2[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)ccc1-c1ccccc1 |r| Show InChI InChI=1S/C27H31N5O7/c33-10-4-5-11-38-19-12-16(8-9-18(19)17-6-2-1-3-7-17)13-28-27-31-21-24(29-15-30-25(21)37)32(27)26-23(36)22(35)20(14-34)39-26/h1-3,6-9,12,15,20,22-23,26,33-36H,4-5,10-11,13-14H2,(H,28,31)(H,29,30,37)/t20-,22-,23-,26-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of rat CNT2 expressed in African green monkey COS7 cells assessed as reduction of [14C]-inosine uptake by liquid scintillation counting an...				J Med Chem 59: 3719-31 (2016) Article DOI: 10.1021/acs.jmedchem.5b01884 BindingDB Entry DOI: 10.7270/Q2ZW1NT8
					More data for this Ligand-Target Pair