Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Potassium channel subfamily K member 4 (Homo sapiens (Human)) | BDBM50514764 (CHEMBL4552751) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 1.53E+4 | n/a | n/a | n/a | n/a |
East China Normal University Curated by ChEMBL | Assay Description Activation of recombinant human TRAAK expressed in HEK293T cells assessed as increase in K+ current amplitude by whole cell voltage clamp electrophys... | J Med Chem 63: 3665-3677 (2020) Article DOI: 10.1021/acs.jmedchem.9b02163 BindingDB Entry DOI: 10.7270/Q25T3PTM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium channel subfamily K member 4 (Homo sapiens (Human)) | BDBM50180656 (CHEMBL3818503) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a |
Universit£ Clermont Auvergne Curated by ChEMBL | Assay Description Activation of TRAAK (unknown origin) expressed in Xenopus oocytes assessed as increase in channel currents | J Med Chem 59: 5149-57 (2016) Article DOI: 10.1021/acs.jmedchem.5b00671 BindingDB Entry DOI: 10.7270/Q2319XSS | |||||||||||
More data for this Ligand-Target Pair |