Compile Data Set for Download or QSAR

Found 11 hits of kd data for polymerid = 50007158,5264   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-adrenergic receptor kinase 1 (Homo sapiens (Human))	BDBM50173313 (CHEMBL1738878) Show SMILES CCCn1c(CNc2cccc(c2)C(=O)NCc2c(F)cccc2F)nnc1-c1ccncn1 Show InChI InChI=1S/C24H23F2N7O/c1-2-11-33-22(31-32-23(33)21-9-10-27-15-30-21)14-28-17-6-3-5-16(12-17)24(34)29-13-18-19(25)7-4-8-20(18)26/h3-10,12,15,28H,2,11,13-14H2,1H3,(H,29,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to full length human GRK2 by Thermofluor thermal shift assay				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127602 BindingDB Entry DOI: 10.7270/Q2H135PS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Beta-adrenergic receptor kinase 1 (Homo sapiens (Human))	BDBM25392 (4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...) Show SMILES CC(C)NCC(O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,11-15H,6H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a
Merck, Sharp, and Dohme Research Laboratories					Assay Description The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.				J Biol Chem 264: 13572-8 (1989) BindingDB Entry DOI: 10.7270/Q29G5KDJ
					More data for this Ligand-Target Pair
Beta-adrenergic receptor kinase 1 (Homo sapiens (Human))	BDBM84342 (4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol...) Show SMILES CNCC(O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a
Merck, Sharp, and Dohme Research Laboratories					Assay Description The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.				J Biol Chem 264: 13572-8 (1989) BindingDB Entry DOI: 10.7270/Q29G5KDJ
					More data for this Ligand-Target Pair
Beta-adrenergic receptor kinase 1 (Homo sapiens (Human))	BDBM22416 ((3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-f...) Show SMILES Fc1ccc(cc1)[C@@H]1CCNC[C@H]1COc1ccc2OCOc2c1 Show InChI InChI=1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	2.98E+3	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to full length human GRK2 by Thermofluor thermal shift assay				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127602 BindingDB Entry DOI: 10.7270/Q2H135PS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Beta-adrenergic receptor kinase 1 (Homo sapiens (Human))	BDBM50554259 (CHEMBL4788026) Show SMILES O=c1n(Cc2ccccc2)cnc2cc(ccc12)-c1cn[nH]c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	3.33E+3	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to full length human GRK2 by Thermofluor thermal shift assay				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127602 BindingDB Entry DOI: 10.7270/Q2H135PS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Beta-adrenergic receptor kinase 1 (Homo sapiens (Human))	BDBM92678 (2-(tert-butylamino)-1-phenylethan-1-ol, 4) Show SMILES CC(C)(C)NCC(O)c1ccccc1 Show InChI InChI=1S/C12H19NO/c1-12(2,3)13-9-11(14)10-7-5-4-6-8-10/h4-8,11,13-14H,9H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a
Merck, Sharp, and Dohme Research Laboratories					Assay Description The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.				J Biol Chem 264: 13572-8 (1989) BindingDB Entry DOI: 10.7270/Q29G5KDJ
					More data for this Ligand-Target Pair
Beta-adrenergic receptor kinase 1 (Homo sapiens (Human))	BDBM92680 (4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenol, 8) Show SMILES CC(C)NCC(O)c1ccc(O)cc1 Show InChI InChI=1S/C11H17NO2/c1-8(2)12-7-11(14)9-3-5-10(13)6-4-9/h3-6,8,11-14H,7H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	5.20E+3	n/a	n/a	n/a	n/a	n/a
Merck, Sharp, and Dohme Research Laboratories					Assay Description The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.				J Biol Chem 264: 13572-8 (1989) BindingDB Entry DOI: 10.7270/Q29G5KDJ
					More data for this Ligand-Target Pair
Beta-adrenergic receptor kinase 1 (Homo sapiens (Human))	BDBM25770 (5-[2-(tert-butylamino)-1-hydroxyethyl]benzene-1,3-...) Show SMILES CC(C)(C)NCC(O)c1cc(O)cc(O)c1 Show InChI InChI=1S/C12H19NO3/c1-12(2,3)13-7-11(16)8-4-9(14)6-10(15)5-8/h4-6,11,13-16H,7H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a
Merck, Sharp, and Dohme Research Laboratories					Assay Description The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.				J Biol Chem 264: 13572-8 (1989) BindingDB Entry DOI: 10.7270/Q29G5KDJ
					More data for this Ligand-Target Pair
Beta-adrenergic receptor kinase 1 (Homo sapiens (Human))	BDBM50295572 (5-(1-Hydroxy-2-isopropylamino-ethyl)-benzene-1,3-d...) Show SMILES CC(C)NCC(O)c1cc(O)cc(O)c1 Show InChI InChI=1S/C11H17NO3/c1-7(2)12-6-11(15)8-3-9(13)5-10(14)4-8/h3-5,7,11-15H,6H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a
Merck, Sharp, and Dohme Research Laboratories					Assay Description The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.				J Biol Chem 264: 13572-8 (1989) BindingDB Entry DOI: 10.7270/Q29G5KDJ
					More data for this Ligand-Target Pair
Beta-adrenergic receptor kinase 1 (Homo sapiens (Human))	BDBM92679 (3-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenol, 7) Show SMILES CC(C)NCC(O)c1cccc(O)c1 Show InChI InChI=1S/C11H17NO2/c1-8(2)12-7-11(14)9-4-3-5-10(13)6-9/h3-6,8,11-14H,7H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a
Merck, Sharp, and Dohme Research Laboratories					Assay Description The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.				J Biol Chem 264: 13572-8 (1989) BindingDB Entry DOI: 10.7270/Q29G5KDJ
					More data for this Ligand-Target Pair
Beta-adrenergic receptor kinase 1 (Homo sapiens (Human))	BDBM46041 (1-(3,4-dihydroxyphenyl)-2-(isopropylamino)ethanone...) Show SMILES CC(C)NCC(=O)c1ccc(O)c(O)c1 Show InChI InChI=1S/C11H15NO3/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8/h3-5,7,12-14H,6H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	9.00E+5	n/a	n/a	n/a	n/a	n/a
Merck, Sharp, and Dohme Research Laboratories					Assay Description The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.				J Biol Chem 264: 13572-8 (1989) BindingDB Entry DOI: 10.7270/Q29G5KDJ
					More data for this Ligand-Target Pair