Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50461446 (CHEMBL4227742) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 860 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min... | Bioorg Med Chem Lett 28: 1911-1914 (2018) Article DOI: 10.1016/j.bmcl.2018.03.077 BindingDB Entry DOI: 10.7270/Q25Q4ZRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50450891 (CHEMBL4212280) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in neutral lipid synthesis incubated for 6 hrs using [1-14C]ole... | J Nat Prod 80: 1161-1166 (2017) Article DOI: 10.1021/acs.jnatprod.7b00137 BindingDB Entry DOI: 10.7270/Q2251MS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50281511 (Acetic acid (S)-1-(11-hydroxy-4-methoxy-9-methyl-5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in neutral lipid synthesis incubated for 6 hrs using [1-14C]ole... | J Nat Prod 80: 1161-1166 (2017) Article DOI: 10.1021/acs.jnatprod.7b00137 BindingDB Entry DOI: 10.7270/Q2251MS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50204552 (CHEMBL3959948) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas... | Bioorg Med Chem Lett 26: 5899-5901 (2016) Article DOI: 10.1016/j.bmcl.2016.11.008 BindingDB Entry DOI: 10.7270/Q2D220KD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50281511 (Acetic acid (S)-1-(11-hydroxy-4-methoxy-9-methyl-5...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cell microsomal fractions assessed as reduction in neutral lipid synthesis incubated for 6 ... | J Nat Prod 80: 1161-1166 (2017) Article DOI: 10.1021/acs.jnatprod.7b00137 BindingDB Entry DOI: 10.7270/Q2251MS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50461447 (CHEMBL4228016) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrs | Bioorg Med Chem Lett 28: 1911-1914 (2018) Article DOI: 10.1016/j.bmcl.2018.03.077 BindingDB Entry DOI: 10.7270/Q25Q4ZRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50450893 (CHEMBL4207391) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in neutral lipid synthesis incubated for 6 hrs using [1-14C]ole... | J Nat Prod 80: 1161-1166 (2017) Article DOI: 10.1021/acs.jnatprod.7b00137 BindingDB Entry DOI: 10.7270/Q2251MS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50461446 (CHEMBL4227742) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrs | Bioorg Med Chem Lett 28: 1911-1914 (2018) Article DOI: 10.1016/j.bmcl.2018.03.077 BindingDB Entry DOI: 10.7270/Q25Q4ZRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50204547 (CHEMBL3923673) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas... | Bioorg Med Chem Lett 26: 5899-5901 (2016) Article DOI: 10.1016/j.bmcl.2016.11.008 BindingDB Entry DOI: 10.7270/Q2D220KD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50360305 (CHEMBL409855 | US9149492, Beauveriolide III) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min... | Bioorg Med Chem Lett 28: 1911-1914 (2018) Article DOI: 10.1016/j.bmcl.2018.03.077 BindingDB Entry DOI: 10.7270/Q25Q4ZRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50461447 (CHEMBL4228016) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min... | Bioorg Med Chem Lett 28: 1911-1914 (2018) Article DOI: 10.1016/j.bmcl.2018.03.077 BindingDB Entry DOI: 10.7270/Q25Q4ZRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50461448 (CHEMBL4227559) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrs | Bioorg Med Chem Lett 28: 1911-1914 (2018) Article DOI: 10.1016/j.bmcl.2018.03.077 BindingDB Entry DOI: 10.7270/Q25Q4ZRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50461448 (CHEMBL4227559) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 isolated from CHO cell microsomes assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 5 min... | Bioorg Med Chem Lett 28: 1911-1914 (2018) Article DOI: 10.1016/j.bmcl.2018.03.077 BindingDB Entry DOI: 10.7270/Q25Q4ZRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50204550 (CHEMBL3916935) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas... | Bioorg Med Chem Lett 26: 5899-5901 (2016) Article DOI: 10.1016/j.bmcl.2016.11.008 BindingDB Entry DOI: 10.7270/Q2D220KD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50204553 (CHEMBL3971022) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas... | Bioorg Med Chem Lett 26: 5899-5901 (2016) Article DOI: 10.1016/j.bmcl.2016.11.008 BindingDB Entry DOI: 10.7270/Q2D220KD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50204545 (CHEMBL3898917) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas... | Bioorg Med Chem Lett 26: 5899-5901 (2016) Article DOI: 10.1016/j.bmcl.2016.11.008 BindingDB Entry DOI: 10.7270/Q2D220KD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50450891 (CHEMBL4212280) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cell microsomal fractions assessed as reduction in neutral lipid synthesis incubated for 6 ... | J Nat Prod 80: 1161-1166 (2017) Article DOI: 10.1021/acs.jnatprod.7b00137 BindingDB Entry DOI: 10.7270/Q2251MS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50450892 (CHEMBL4207917) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in neutral lipid synthesis incubated for 6 hrs using [1-14C]ole... | J Nat Prod 80: 1161-1166 (2017) Article DOI: 10.1021/acs.jnatprod.7b00137 BindingDB Entry DOI: 10.7270/Q2251MS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50450893 (CHEMBL4207391) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 9.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cell microsomal fractions assessed as reduction in neutral lipid synthesis incubated for 6 ... | J Nat Prod 80: 1161-1166 (2017) Article DOI: 10.1021/acs.jnatprod.7b00137 BindingDB Entry DOI: 10.7270/Q2251MS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50204558 (CHEMBL3960874) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas... | Bioorg Med Chem Lett 26: 5899-5901 (2016) Article DOI: 10.1016/j.bmcl.2016.11.008 BindingDB Entry DOI: 10.7270/Q2D220KD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50242257 (2-((1R,2S,4aS)-1,2,4a,5-Tetramethyl-1,2,3,4,4a,7,8...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.48E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells using [1-14C]oleic acid incubated for 6 hrs by TLC based method | Bioorg Med Chem Lett 29: 2283-2285 (2019) Article DOI: 10.1016/j.bmcl.2019.06.026 BindingDB Entry DOI: 10.7270/Q2NK3JC2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50204551 (CHEMBL3958875) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas... | Bioorg Med Chem Lett 26: 5899-5901 (2016) Article DOI: 10.1016/j.bmcl.2016.11.008 BindingDB Entry DOI: 10.7270/Q2D220KD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50196069 (CHEMBL3965313) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.91E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells using [1-14C]oleic acid incubated for 6 hrs by TLC based method | Bioorg Med Chem Lett 29: 2283-2285 (2019) Article DOI: 10.1016/j.bmcl.2019.06.026 BindingDB Entry DOI: 10.7270/Q2NK3JC2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50360305 (CHEMBL409855 | US9149492, Beauveriolide III) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Tohoku Medical and Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as decrease in [14C]CE synthesis from [14C]oleic acid after 6 hrs | Bioorg Med Chem Lett 28: 1911-1914 (2018) Article DOI: 10.1016/j.bmcl.2018.03.077 BindingDB Entry DOI: 10.7270/Q25Q4ZRC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50204555 (CHEMBL3983935) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas... | Bioorg Med Chem Lett 26: 5899-5901 (2016) Article DOI: 10.1016/j.bmcl.2016.11.008 BindingDB Entry DOI: 10.7270/Q2D220KD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50204556 (CHEMBL3941429) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas... | Bioorg Med Chem Lett 26: 5899-5901 (2016) Article DOI: 10.1016/j.bmcl.2016.11.008 BindingDB Entry DOI: 10.7270/Q2D220KD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50450892 (CHEMBL4207917) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Keio University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cell microsomal fractions assessed as reduction in neutral lipid synthesis incubated for 6 ... | J Nat Prod 80: 1161-1166 (2017) Article DOI: 10.1021/acs.jnatprod.7b00137 BindingDB Entry DOI: 10.7270/Q2251MS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sterol O-acyltransferase 2 (Chlorocebus aethiops) | BDBM50204548 (CHEMBL3932453) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University Curated by ChEMBL | Assay Description Inhibition of African green monkey SOAT2 expressed in CHO cells assessed as reduction in [14C]cholesteryl ester formation from [1-14C]oleic acid meas... | Bioorg Med Chem Lett 26: 5899-5901 (2016) Article DOI: 10.1016/j.bmcl.2016.11.008 BindingDB Entry DOI: 10.7270/Q2D220KD | |||||||||||
More data for this Ligand-Target Pair |