Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ferrochelatase, mitochondrial (Homo sapiens (Human)) | BDBM50396483 (PLX-4032 | RG 7204 | Ro 5185426 | US10570155, Vemu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a |
The University of Sydney Curated by ChEMBL | Assay Description Stabilization of FECH in human K562 cells after 1 hr by thermal shift assay | Nat Rev Drug Discov 16: 424-440 (2017) Article DOI: 10.1038/nrd.2016.266 BindingDB Entry DOI: 10.7270/Q2125VNC | |||||||||||
More data for this Ligand-Target Pair |