BindingDB PrimarySearch

Found 9 hits of kd data for polymerid = 5023
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neutrophil elastase (Homo sapiens (Human))	BDBM50303364 (1-(4-((Benzo[d]oxazol-2-ylthio)methyl)phenyl)-3,3-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a
University of Lisbon Curated by ChEMBL					Assay Description Inhibition of human leukocyte elastase after 20 mins				J Med Chem 53: 241-53 (2010) Article DOI: 10.1021/jm901082k BindingDB Entry DOI: 10.7270/Q23B607D
University of Lisbon Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50303363 (2-(4-(3,3-Diethyl-2,4-dioxoazetidin-1-yl)benzylthi...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a
University of Lisbon Curated by ChEMBL					Assay Description Inhibition of human leukocyte elastase after 20 mins				J Med Chem 53: 241-53 (2010) Article DOI: 10.1021/jm901082k BindingDB Entry DOI: 10.7270/Q23B607D
University of Lisbon Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50235614 (3,3-diethyl-1-(4-tolyl)azetidine-2,4-dione \| 3,3-d...) Show SMILES CCC1(CC)C(=O)N(C1=O)c1ccc(C)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	48.2	n/a	n/a	n/a	n/a	n/a
University of Lisbon Curated by ChEMBL					Assay Description Inhibition of human leukocyte elastase after 20 mins				J Med Chem 53: 241-53 (2010) Article DOI: 10.1021/jm901082k BindingDB Entry DOI: 10.7270/Q23B607D
University of Lisbon Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50235612 (1-(4-chlorophenyl)-3,3-diethylazetidine-2,4-dione ...) Show SMILES CCC1(CC)C(=O)N(C1=O)c1ccc(Cl)cc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	57.9	n/a	n/a	n/a	n/a	n/a
University of Lisbon Curated by ChEMBL					Assay Description Inhibition of human leukocyte elastase after 20 mins				J Med Chem 53: 241-53 (2010) Article DOI: 10.1021/jm901082k BindingDB Entry DOI: 10.7270/Q23B607D
University of Lisbon Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50303365 (1-(2-((Benzo[d]oxazol-2-ylthio)methyl)phenyl)-3,3-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	205	n/a	n/a	n/a	n/a	n/a
University of Lisbon Curated by ChEMBL					Assay Description Inhibition of human leukocyte elastase after 20 mins				J Med Chem 53: 241-53 (2010) Article DOI: 10.1021/jm901082k BindingDB Entry DOI: 10.7270/Q23B607D
University of Lisbon Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50303362 (1-(2-((Benzo[d]thiazol-2-ylthio)methyl)phenyl)-3,3...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	283	n/a	n/a	n/a	n/a	n/a
University of Lisbon Curated by ChEMBL					Assay Description Inhibition of human leukocyte elastase after 20 mins				J Med Chem 53: 241-53 (2010) Article DOI: 10.1021/jm901082k BindingDB Entry DOI: 10.7270/Q23B607D
University of Lisbon Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50303367 (1-(2-((5-Phenyl-1,3,4-oxadiazol-2-ylthio)methyl)ph...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	353	n/a	n/a	n/a	n/a	n/a
University of Lisbon Curated by ChEMBL					Assay Description Inhibition of human leukocyte elastase after 20 mins				J Med Chem 53: 241-53 (2010) Article DOI: 10.1021/jm901082k BindingDB Entry DOI: 10.7270/Q23B607D
University of Lisbon Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50084227 (2-(diethylamino)-5-methyl-4-oxo-4H-thieno[2,3-d][1...) Show SMILES CCN(CC)c1nc2sc(C(N)=O)c(C)c2c(=O)o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a
University of Leipzig Curated by ChEMBL					Assay Description Inhibitory activity of the compound was tested against human leukocyte elastase				J Med Chem 42: 5437-47 (2000) BindingDB Entry DOI: 10.7270/Q2K936RG
University of Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50084228 (2-(diethylamino)-5-methyl-4H-thieno[2,3-d][1,3]oxa...) Show SMILES CCN(CC)c1nc2scc(C)c2c(=O)o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a
University of Leipzig Curated by ChEMBL					Assay Description Inhibitory activity of the compound was tested against human leukocyte elastase				J Med Chem 42: 5437-47 (2000) BindingDB Entry DOI: 10.7270/Q2K936RG
University of Leipzig Curated by ChEMBL					More data for this Ligand-Target Pair