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Compile Data Set for Download or QSAR

Found 2 hits of ec50 for UniProtKB: P14679   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosinase


(Homo sapiens (Human))
BDBM50293593
PNG
(4-(2-aminothiazol-4-yl)benzene-1,3-diol | CHEMBL54...)
Show SMILES Nc1nc(cs1)-c1ccc(O)cc1O
Show InChI InChI=1S/C9H8N2O2S/c10-9-11-7(4-14-9)6-2-1-5(12)3-8(6)13/h1-4,12-13H,(H2,10,11)
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

n/an/an/an/a 51n/an/an/an/a


TBA



Citation and Details
More data for this
Ligand-Target Pair
Tyrosinase


(Homo sapiens (Human))
BDBM50322068
PNG
((-)-N-Formylanonaine | CHEMBL1170090)
Show SMILES O=CN1CCc2cc3OCOc3c3-c4ccccc4C[C@@H]1c23 |r|
Show InChI InChI=1S/C18H15NO3/c20-9-19-6-5-12-8-15-18(22-10-21-15)17-13-4-2-1-3-11(13)7-14(19)16(12)17/h1-4,8-9,14H,5-7,10H2/t14-/m1/s1
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 9.00E+4n/an/an/an/a



Kaohsiung Medical University

Curated by ChEMBL


Assay Description
Inhibition of tyrosinase in human HEMn-MP assessed as reduction of melanin level after 2 days by spectrophotometric analysis


Bioorg Med Chem 18: 5241-7 (2010)


Article DOI: 10.1016/j.bmc.2010.05.045
BindingDB Entry DOI: 10.7270/Q2JS9RFV
More data for this
Ligand-Target Pair