Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM161472 (US9108978, 2.02) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 30 | -10.7 | 203 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM161468 (US9108978, 6.09) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB US Patent | 90 | -9.99 | 530 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM92383 (Biotin triazole, 14) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide | Assay Description In vitro enzyme inhibition using biotin protein ligase. | J Biol Chem 287: 17823-32 (2012) Article DOI: 10.1074/jbc.M112.356576 BindingDB Entry DOI: 10.7270/Q2DJ5D7V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM161470 (US9108978, 4.01) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB US Patent | 660 | -8.76 | 4.00E+3 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM161469 (US9108978, 6.07) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.17E+3 | -8.41 | 7.00E+3 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM92382 (Biotin triazole, 13) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide | Assay Description In vitro enzyme inhibition using biotin protein ligase. | J Biol Chem 287: 17823-32 (2012) Article DOI: 10.1074/jbc.M112.356576 BindingDB Entry DOI: 10.7270/Q2DJ5D7V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM92378 (Biotin triazole, 5) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide | Assay Description In vitro enzyme inhibition using biotin protein ligase. | J Biol Chem 287: 17823-32 (2012) Article DOI: 10.1074/jbc.M112.356576 BindingDB Entry DOI: 10.7270/Q2DJ5D7V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM161467 (US9108978, 3.25) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.83E+3 | -8.14 | 1.16E+4 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM161471 (US9108978, 6.34) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | >1.00E+4 | >-7.09 | >5.00E+4 | n/a | n/a | n/a | n/a | 8.0 | 37 |
Monash University; Adelaide Research & Innovation Pty Ltd US Patent | Assay Description Quantitation of BPL catalysed 3H-biotin incorporation into the biotin domain substrate was performed as previously described by Polyak et al, J. Biol... | US Patent US9108978 (2015) BindingDB Entry DOI: 10.7270/Q2T43RVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM92385 (Biotin triazole, 16) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide | Assay Description In vitro enzyme inhibition using biotin protein ligase. | J Biol Chem 287: 17823-32 (2012) Article DOI: 10.1074/jbc.M112.356576 BindingDB Entry DOI: 10.7270/Q2DJ5D7V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM92381 (Biotin triazole, 12) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide | Assay Description In vitro enzyme inhibition using biotin protein ligase. | J Biol Chem 287: 17823-32 (2012) Article DOI: 10.1074/jbc.M112.356576 BindingDB Entry DOI: 10.7270/Q2DJ5D7V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM92380 (Biotin triazole, 11) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide | Assay Description In vitro enzyme inhibition using biotin protein ligase. | J Biol Chem 287: 17823-32 (2012) Article DOI: 10.1074/jbc.M112.356576 BindingDB Entry DOI: 10.7270/Q2DJ5D7V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM92379 (Biotin triazole, 10) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide | Assay Description In vitro enzyme inhibition using biotin protein ligase. | J Biol Chem 287: 17823-32 (2012) Article DOI: 10.1074/jbc.M112.356576 BindingDB Entry DOI: 10.7270/Q2DJ5D7V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bifunctional ligase/repressor BirA (Staphylococcus aureus) | BDBM92384 (Biotin triazole, 15) | PDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Adelaide | Assay Description In vitro enzyme inhibition using biotin protein ligase. | J Biol Chem 287: 17823-32 (2012) Article DOI: 10.1074/jbc.M112.356576 BindingDB Entry DOI: 10.7270/Q2DJ5D7V | |||||||||||
More data for this Ligand-Target Pair |