BindingDB PrimarySearch

Found 16 hits of ki data for polymerid = 5393
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
3-dehydroquinate synthase (Escherichia coli (strain K12))	BDBM50280172 (1,3,4-Trihydroxy-5-phosphonomethyl-cyclohexanecarb...) Show SMILES OC1CC(O)(CC(CP(O)(O)=O)C1O)C(O)=O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid PDB UniChem Similars	Article	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibitory activity against calf thymus ribonucleotide reductase				Bioorg Med Chem Lett 2: 1349-1352 (1992) Article DOI: 10.1016/S0960-894X(00)80510-7 BindingDB Entry DOI: 10.7270/Q2MW2H21
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-dehydroquinate synthase (Escherichia coli (strain K12))	BDBM93206 (2,4,5-trihydroxy-6-(phosphonatomethyl)oxane-2-carb...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard University					Assay Description Enzyme inhibition using dehydroquinate synthase.				Biochemistry 28: 7572-82 (1989) Article DOI: 10.1021/bi00445a011 BindingDB Entry DOI: 10.7270/Q24J0CRS
Harvard University					More data for this Ligand-Target Pair
3-dehydroquinate synthase (Escherichia coli (strain K12))	BDBM50028881 ((1R,3S,4S)-1,4-Dihydroxy-3-phosphonomethyl-cyclohe...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was evaluated for its inhibitory constant against 3-dehydroquinate synthase				J Med Chem 24: 496-9 (1981) BindingDB Entry DOI: 10.7270/Q2K64JTV
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-dehydroquinate synthase (Escherichia coli (strain K12))	BDBM50028881 ((1R,3S,4S)-1,4-Dihydroxy-3-phosphonomethyl-cyclohe...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Association rate constant of the compound was determined against 3-dehydroquinate synthase				Bioorg Med Chem Lett 2: 1349-1352 (1992) Article DOI: 10.1016/S0960-894X(00)80510-7 BindingDB Entry DOI: 10.7270/Q2MW2H21
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-dehydroquinate synthase (Escherichia coli (strain K12))	BDBM50100860 (3,4-Dihydroxy-5-phosphonomethyl-benzoic acid \| CHE...) Show SMILES OC(=O)c1cc(O)c(O)c(CP(O)(O)=O)c1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition constant for binding to Zn2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli				Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH
Michigan State University Curated by ChEMBL					More data for this Ligand-Target Pair
3-dehydroquinate synthase (Escherichia coli (strain K12))	BDBM50028883 ((1S,3S,5R)-1,3-Dihydroxy-5-phosphonomethyl-cyclohe...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Association rate constant of the compound was determined against 3-dehydroquinate synthase				Bioorg Med Chem Lett 2: 1349-1352 (1992) Article DOI: 10.1016/S0960-894X(00)80510-7 BindingDB Entry DOI: 10.7270/Q2MW2H21
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
3-dehydroquinate synthase (Escherichia coli (strain K12))	BDBM50100862 (3,4-Dihydroxy-5-(2-phosphono-ethyl)-benzoic acid \|...) Show SMILES OC(=O)c1cc(O)c(O)c(CCP(O)(O)=O)c1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition constant for binding to Zn2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli				Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH
Michigan State University Curated by ChEMBL					More data for this Ligand-Target Pair
3-dehydroquinate synthase (Escherichia coli (strain K12))	BDBM50100862 (3,4-Dihydroxy-5-(2-phosphono-ethyl)-benzoic acid \|...) Show SMILES OC(=O)c1cc(O)c(O)c(CCP(O)(O)=O)c1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition constant for binding to Co2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli				Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH
Michigan State University Curated by ChEMBL					More data for this Ligand-Target Pair
3-dehydroquinate synthase (Escherichia coli (strain K12))	BDBM50100860 (3,4-Dihydroxy-5-phosphonomethyl-benzoic acid \| CHE...) Show SMILES OC(=O)c1cc(O)c(O)c(CP(O)(O)=O)c1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition constant for binding to Co2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli				Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH
Michigan State University Curated by ChEMBL					More data for this Ligand-Target Pair
3-dehydroquinate synthase (Escherichia coli (strain K12))	BDBM93205 (4,5-dihydroxy-6-(phosphonatomethyl)oxane-2-carboxy...) Show SMILES OC1CC(OC(CP([O-])([O-])=O)C1O)C([O-])=O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard University					Assay Description Enzyme inhibition using dehydroquinate synthase.				Biochemistry 28: 7572-82 (1989) Article DOI: 10.1021/bi00445a011 BindingDB Entry DOI: 10.7270/Q24J0CRS
Harvard University					More data for this Ligand-Target Pair
3-dehydroquinate synthase (Escherichia coli (strain K12))	BDBM50100861 (3,4-Dihydroxybenzoate, VIII \| 3,4-dihydroxybenzoic...) Show SMILES OC(=O)c1ccc(O)c(O)c1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition constant for binding to Co2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli				Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH
Michigan State University Curated by ChEMBL					More data for this Ligand-Target Pair
3-dehydroquinate synthase (Escherichia coli (strain K12))	BDBM50100861 (3,4-Dihydroxybenzoate, VIII \| 3,4-dihydroxybenzoic...) Show SMILES OC(=O)c1ccc(O)c(O)c1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition constant for binding to Zn2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli				Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH
Michigan State University Curated by ChEMBL					More data for this Ligand-Target Pair
3-dehydroquinate synthase (Escherichia coli (strain K12))	BDBM50100859 (CHEMBL440285 \| [2-(2,3-Dihydroxy-phenyl)-ethyl]-ph...) Show SMILES Oc1cccc(CCP(O)(O)=O)c1O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition constant for binding to Zn2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli				Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH
Michigan State University Curated by ChEMBL					More data for this Ligand-Target Pair
3-dehydroquinate synthase (Escherichia coli (strain K12))	BDBM50100859 (CHEMBL440285 \| [2-(2,3-Dihydroxy-phenyl)-ethyl]-ph...) Show SMILES Oc1cccc(CCP(O)(O)=O)c1O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition constant for binding to Co2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli				Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH
Michigan State University Curated by ChEMBL					More data for this Ligand-Target Pair
3-dehydroquinate synthase (Escherichia coli (strain K12))	BDBM26188 (α-CA inhibitor, 12 \| 1,2-Dihydroxybenzene, XI...) Show SMILES Oc1ccccc1O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	6.30E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition constant for binding to Zn2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli				Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH
Michigan State University Curated by ChEMBL					More data for this Ligand-Target Pair
3-dehydroquinate synthase (Escherichia coli (strain K12))	BDBM26188 (α-CA inhibitor, 12 \| 1,2-Dihydroxybenzene, XI...) Show SMILES Oc1ccccc1O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	8.80E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Michigan State University Curated by ChEMBL					Assay Description Inhibition constant for binding to Co2+ form of 3-dehydroquinate synthase (DHQ) purified from E. coli				Bioorg Med Chem Lett 11: 1493-6 (2001) BindingDB Entry DOI: 10.7270/Q2S75FMH
Michigan State University Curated by ChEMBL					More data for this Ligand-Target Pair