BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1696 hits of ic50 data for polymerid = 5468   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146972
PNG
((S)-4-(4-chlorobenzylamino)-2-amino-1-(piperidin-1...)
Show SMILES N[C@@H](CCNCc1ccc(Cl)cc1)C(=O)N1CCCCC1 |r|
Show InChI InChI=1S/C16H24ClN3O/c17-14-6-4-13(5-7-14)12-19-9-8-15(18)16(21)20-10-2-1-3-11-20/h4-7,15,19H,1-3,8-12,18H2/t15-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.220n/an/an/an/an/an/a



Laboratory of Medicinal Chemistry University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2


Bioorg Med Chem Lett 16: 4777-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.082
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146987
PNG
((S)-2-Amino-4-[(4-chloro-benzyl)-methyl-amino]-1-p...)
Show SMILES CN(CC[C@H](N)C(=O)N1CCCCC1)Cc1ccc(Cl)cc1
Show InChI InChI=1S/C17H26ClN3O/c1-20(13-14-5-7-15(18)8-6-14)12-9-16(19)17(22)21-10-3-2-4-11-21/h5-8,16H,2-4,9-13,19H2,1H3/t16-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.220n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146971
PNG
(2-(S)-Amino-4-(2-chloro-benzylamino)-1-piperidin-1...)
Show SMILES N[C@@H](CCNCc1ccccc1Cl)C(=O)N1CCCCC1
Show InChI InChI=1S/C16H24ClN3O/c17-14-7-3-2-6-13(14)12-19-9-8-15(18)16(21)20-10-4-1-5-11-20/h2-3,6-7,15,19H,1,4-5,8-12,18H2/t15-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.230n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146974
PNG
((S)-2-Amino-4-(4-chloro-benzylamino)-1-(4-fluoro-p...)
Show SMILES N[C@@H](CCNCc1ccc(Cl)cc1)C(=O)N1CCC(F)CC1
Show InChI InChI=1S/C16H23ClFN3O/c17-13-3-1-12(2-4-13)11-20-8-5-15(19)16(22)21-9-6-14(18)7-10-21/h1-4,14-15,20H,5-11,19H2/t15-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.390n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146973
PNG
(2-(S)-Amino-4-(2-benzyloxy-benzylamino)-1-piperidi...)
Show SMILES N[C@@H](CCNCc1ccccc1OCc1ccccc1)C(=O)N1CCCCC1
Show InChI InChI=1S/C23H31N3O2/c24-21(23(27)26-15-7-2-8-16-26)13-14-25-17-20-11-5-6-12-22(20)28-18-19-9-3-1-4-10-19/h1,3-6,9-12,21,25H,2,7-8,13-18,24H2/t21-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.390n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146952
PNG
(2-(S)-Amino-4-(4-benzyloxy-benzylamino)-1-piperidi...)
Show SMILES N[C@@H](CCNCc1ccc(OCc2ccccc2)cc1)C(=O)N1CCCCC1
Show InChI InChI=1S/C23H31N3O2/c24-22(23(27)26-15-5-2-6-16-26)13-14-25-17-19-9-11-21(12-10-19)28-18-20-7-3-1-4-8-20/h1,3-4,7-12,22,25H,2,5-6,13-18,24H2/t22-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.410n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146972
PNG
((S)-4-(4-chlorobenzylamino)-2-amino-1-(piperidin-1...)
Show SMILES N[C@@H](CCNCc1ccc(Cl)cc1)C(=O)N1CCCCC1 |r|
Show InChI InChI=1S/C16H24ClN3O/c17-14-6-4-13(5-7-14)12-19-9-8-15(18)16(21)20-10-2-1-3-11-20/h4-7,15,19H,1-3,8-12,18H2/t15-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.480n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50196928
PNG
((R)-1-((S)-2,4-diaminobutanamido)pentylboronic aci...)
Show SMILES CCCC[C@H](NC(=O)[C@@H](N)CCN)B(O)O
Show InChI InChI=1S/C9H22BN3O3/c1-2-3-4-8(10(15)16)13-9(14)7(12)5-6-11/h7-8,15-16H,2-6,11-12H2,1H3,(H,13,14)/t7-,8-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.480n/an/an/an/an/an/a



Tufts University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of human DPP2


Bioorg Med Chem Lett 17: 507-10 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.012
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146972
PNG
((S)-4-(4-chlorobenzylamino)-2-amino-1-(piperidin-1...)
Show SMILES N[C@@H](CCNCc1ccc(Cl)cc1)C(=O)N1CCCCC1 |r|
Show InChI InChI=1S/C16H24ClN3O/c17-14-6-4-13(5-7-14)12-19-9-8-15(18)16(21)20-10-2-1-3-11-20/h4-7,15,19H,1-3,8-12,18H2/t15-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.480n/an/an/an/an/an/a



University of Antwerp (UA)

Curated by ChEMBL


Assay Description
Inhibition of DPP2


J Med Chem 54: 5737-46 (2011)


Article DOI: 10.1021/jm200383j
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50171546
PNG
((S)-2,4-Diamino-N-((R)-1-boron-dihydroxide-pentyl)...)
Show SMILES CCCC[C@@H](NC(=O)[C@@H](N)CCN)B(O)O
Show InChI InChI=1S/C9H22BN3O3/c1-2-3-4-8(10(15)16)13-9(14)7(12)5-6-11/h7-8,15-16H,2-6,11-12H2,1H3,(H,13,14)/t7-,8+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.480n/an/an/an/an/an/a



ActivX Biosciences

Curated by ChEMBL


Assay Description
Inhibitory concentration against human dipeptidylpeptidase 7


Bioorg Med Chem Lett 15: 4256-60 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.076
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146956
PNG
((S)-2-Amino-4-(4-chloro-benzylamino)-1-(4-methyl-p...)
Show SMILES CC1CCN(CC1)C(=O)[C@@H](N)CCNCc1ccc(Cl)cc1
Show InChI InChI=1S/C17H26ClN3O/c1-13-7-10-21(11-8-13)17(22)16(19)6-9-20-12-14-2-4-15(18)5-3-14/h2-5,13,16,20H,6-12,19H2,1H3/t16-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.550n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146967
PNG
((S)-2-Amino-4-dibenzylamino-1-piperidin-1-yl-butan...)
Show SMILES N[C@@H](CCN(Cc1ccccc1)Cc1ccccc1)C(=O)N1CCCCC1
Show InChI InChI=1S/C23H31N3O/c24-22(23(27)26-15-8-3-9-16-26)14-17-25(18-20-10-4-1-5-11-20)19-21-12-6-2-7-13-21/h1-2,4-7,10-13,22H,3,8-9,14-19,24H2/t22-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.600n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146985
PNG
((S)-2-Amino-4-(4-chloro-benzylamino)-1-(3-fluoro-p...)
Show SMILES N[C@@H](CCNCc1ccc(Cl)cc1)C(=O)N1CCCC(F)C1
Show InChI InChI=1S/C16H23ClFN3O/c17-13-5-3-12(4-6-13)10-20-8-7-15(19)16(22)21-9-1-2-14(18)11-21/h3-6,14-15,20H,1-2,7-11,19H2/t14?,15-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.620n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50191168
PNG
((2S,4S)-4-(4-chlorobenzylamino)-2-amino-1-(piperid...)
Show SMILES C[C@@H](C[C@H](N)C(=O)N1CCCCC1)NCc1ccc(Cl)cc1
Show InChI InChI=1S/C17H26ClN3O/c1-13(20-12-14-5-7-15(18)8-6-14)11-16(19)17(22)21-9-3-2-4-10-21/h5-8,13,16,20H,2-4,9-12,19H2,1H3/t13-,16-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.620n/an/an/an/an/an/a



Laboratory of Medicinal Chemistry University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2


Bioorg Med Chem Lett 16: 4777-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.082
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146977
PNG
(2-(S)-Amino-4-(4-methoxy-benzylamino)-1-piperidin-...)
Show SMILES COc1ccc(CNCC[C@H](N)C(=O)N2CCCCC2)cc1
Show InChI InChI=1S/C17H27N3O2/c1-22-15-7-5-14(6-8-15)13-19-10-9-16(18)17(21)20-11-3-2-4-12-20/h5-8,16,19H,2-4,9-13,18H2,1H3/t16-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.660n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50171555
PNG
((S)-2,4-Diamino-1-(2-boron-dihydroxide-pyrrolidin-...)
Show SMILES NCC[C@H](N)C(=O)N1CCC[C@@H]1B(O)O
Show InChI InChI=1S/C8H18BN3O3/c10-4-3-6(11)8(13)12-5-1-2-7(12)9(14)15/h6-7,14-15H,1-5,10-11H2/t6-,7+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.720n/an/an/an/an/an/a



ActivX Biosciences

Curated by ChEMBL


Assay Description
Inhibitory concentration against human dipeptidylpeptidase 7


Bioorg Med Chem Lett 15: 4256-60 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.076
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146964
PNG
(2-(S)-Amino-1-piperidin-1-yl-4-[(pyridin-4-ylmethy...)
Show SMILES N[C@@H](CCNCc1ccncc1)C(=O)N1CCCCC1
Show InChI InChI=1S/C15H24N4O/c16-14(15(20)19-10-2-1-3-11-19)6-9-18-12-13-4-7-17-8-5-13/h4-5,7-8,14,18H,1-3,6,9-12,16H2/t14-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.75n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146957
PNG
(2-(S)-Amino-1-piperidin-1-yl-4-[(thiophen-2-ylmeth...)
Show SMILES N[C@@H](CCNCc1cccs1)C(=O)N1CCCCC1
Show InChI InChI=1S/C14H23N3OS/c15-13(14(18)17-8-2-1-3-9-17)6-7-16-11-12-5-4-10-19-12/h4-5,10,13,16H,1-3,6-9,11,15H2/t13-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.800n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50196929
PNG
((S)-2,4-diamino-1-((3aR,6aR)-hexahydrocyclopenta[b...)
Show SMILES NCC[C@H](N)C(=O)N1CC[C@H]2CCC[C@@H]12
Show InChI InChI=1S/C11H21N3O/c12-6-4-9(13)11(15)14-7-5-8-2-1-3-10(8)14/h8-10H,1-7,12-13H2/t8-,9+,10-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.880n/an/an/an/an/an/a



Tufts University School of Medicine

Curated by ChEMBL


Assay Description
Inhibition of human DPP2


Bioorg Med Chem Lett 17: 507-10 (2007)


Article DOI: 10.1016/j.bmcl.2006.10.012
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146954
PNG
(2-(S)-Amino-4-phenethylamino-1-piperidin-1-yl-buta...)
Show SMILES N[C@@H](CCNCCc1ccccc1)C(=O)N1CCCCC1
Show InChI InChI=1S/C17H27N3O/c18-16(17(21)20-13-5-2-6-14-20)10-12-19-11-9-15-7-3-1-4-8-15/h1,3-4,7-8,16,19H,2,5-6,9-14,18H2/t16-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.900n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50171648
PNG
(CHEMBL372180 | N-alkyl Gly-boro-Pro derivative)
Show SMILES CCCCCC12CCC(CC1)(CC2)NCC(=O)N1CCC[C@H]1B(O)O
Show InChI InChI=1S/C19H35BN2O3/c1-2-3-4-7-18-8-11-19(12-9-18,13-10-18)21-15-17(23)22-14-5-6-16(22)20(24)25/h16,21,24-25H,2-15H2,1H3/t16-,18?,19?/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1n/an/an/an/an/an/a



ActivX Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against human DPP7 using Ala-Pro-AMC in fluorometric assay


Bioorg Med Chem Lett 15: 4239-42 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.075
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146991
PNG
(2-(S)-Amino-4-[(naphthalen-2-ylmethyl)-amino]-1-pi...)
Show SMILES N[C@@H](CCNCc1ccc2ccccc2c1)C(=O)N1CCCCC1
Show InChI InChI=1S/C20H27N3O/c21-19(20(24)23-12-4-1-5-13-23)10-11-22-15-16-8-9-17-6-2-3-7-18(17)14-16/h2-3,6-9,14,19,22H,1,4-5,10-13,15,21H2/t19-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.10n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146968
PNG
((S)-2-Amino-4-(4-chloro-benzylamino)-1-(3,6-dihydr...)
Show SMILES N[C@@H](CCNCc1ccc(Cl)cc1)C(=O)N1CCC=CC1 |c:19|
Show InChI InChI=1S/C16H22ClN3O/c17-14-6-4-13(5-7-14)12-19-9-8-15(18)16(21)20-10-2-1-3-11-20/h1-2,4-7,15,19H,3,8-12,18H2/t15-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.10n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146955
PNG
(2-(S)-Amino-4-(cyclohexylmethyl-amino)-1-piperidin...)
Show SMILES N[C@@H](CCNCC1CCCCC1)C(=O)N1CCCCC1
Show InChI InChI=1S/C16H31N3O/c17-15(16(20)19-11-5-2-6-12-19)9-10-18-13-14-7-3-1-4-8-14/h14-15,18H,1-13,17H2/t15-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.10n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146950
PNG
((S)-2-Amino-4-(4-chloro-benzylamino)-1-(3-methyl-p...)
Show SMILES CC1CCCN(C1)C(=O)[C@@H](N)CCNCc1ccc(Cl)cc1
Show InChI InChI=1S/C17H26ClN3O/c1-13-3-2-10-21(12-13)17(22)16(19)8-9-20-11-14-4-6-15(18)7-5-14/h4-7,13,16,20H,2-3,8-12,19H2,1H3/t13?,16-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.13n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146960
PNG
(2-(S)-Amino-4-[(naphthalen-1-ylmethyl)-amino]-1-pi...)
Show SMILES N[C@@H](CCNCc1cccc2ccccc12)C(=O)N1CCCCC1
Show InChI InChI=1S/C20H27N3O/c21-19(20(24)23-13-4-1-5-14-23)11-12-22-15-17-9-6-8-16-7-2-3-10-18(16)17/h2-3,6-10,19,22H,1,4-5,11-15,21H2/t19-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.31n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146961
PNG
(2-(S)-Amino-4-(3-chloro-benzylamino)-1-piperidin-1...)
Show SMILES N[C@@H](CCNCc1cccc(Cl)c1)C(=O)N1CCCCC1
Show InChI InChI=1S/C16H24ClN3O/c17-14-6-4-5-13(11-14)12-19-8-7-15(18)16(21)20-9-2-1-3-10-20/h4-6,11,15,19H,1-3,7-10,12,18H2/t15-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.34n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146978
PNG
((S)-2-Amino-4-phenylamino-1-piperidin-1-yl-butan-1...)
Show SMILES N[C@@H](CCNc1ccccc1)C(=O)N1CCCCC1
Show InChI InChI=1S/C15H23N3O/c16-14(15(19)18-11-5-2-6-12-18)9-10-17-13-7-3-1-4-8-13/h1,3-4,7-8,14,17H,2,5-6,9-12,16H2/t14-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146988
PNG
(CHEMBL440325 | N-((S)-3-Amino-4-oxo-4-piperidin-1-...)
Show SMILES CC(=O)NCC[C@H](N)C(=O)N1CCCCC1
Show InChI InChI=1S/C11H21N3O2/c1-9(15)13-6-5-10(12)11(16)14-7-3-2-4-8-14/h10H,2-8,12H2,1H3,(H,13,15)/t10-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.5n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146953
PNG
(2-(S)-Amino-4-(3-methoxy-benzylamino)-1-piperidin-...)
Show SMILES COc1cccc(CNCC[C@H](N)C(=O)N2CCCCC2)c1
Show InChI InChI=1S/C17H27N3O2/c1-22-15-7-5-6-14(12-15)13-19-9-8-16(18)17(21)20-10-3-2-4-11-20/h5-7,12,16,19H,2-4,8-11,13,18H2,1H3/t16-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.77n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50171649
PNG
(CHEMBL196933 | N-alkyl Gly-boro-Pro derivative)
Show SMILES OB(O)[C@@H]1CCCN1C(=O)CNC1CCCCCC1
Show InChI InChI=1S/C13H25BN2O3/c17-13(16-9-5-8-12(16)14(18)19)10-15-11-6-3-1-2-4-7-11/h11-12,15,18-19H,1-10H2/t12-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.80n/an/an/an/an/an/a



ActivX Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against human DPP7 using Ala-Pro-AMC in fluorometric assay


Bioorg Med Chem Lett 15: 4239-42 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.075
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146962
PNG
(CHEMBL101401 | N-((S)-3-Amino-4-oxo-4-piperidin-1-...)
Show SMILES N[C@@H](CCNC(N)=N)C(=O)N1CCCCC1
Show InChI InChI=1S/C10H21N5O/c11-8(4-5-14-10(12)13)9(16)15-6-2-1-3-7-15/h8H,1-7,11H2,(H4,12,13,14)/t8-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.80n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146965
PNG
(2-(S)-Amino-4-(3-phenyl-propylamino)-1-piperidin-1...)
Show SMILES N[C@@H](CCNCCCc1ccccc1)C(=O)N1CCCCC1
Show InChI InChI=1S/C18H29N3O/c19-17(18(22)21-14-5-2-6-15-21)11-13-20-12-7-10-16-8-3-1-4-9-16/h1,3-4,8-9,17,20H,2,5-7,10-15,19H2/t17-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.91n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50171548
PNG
((S)-2-(S)-Amino-1-(2-boron-dihydroxide-pyrrolidin-...)
Show SMILES CCCC[C@H](N)C(=O)N1CCC[C@@H]1B(O)O
Show InChI InChI=1S/C10H21BN2O3/c1-2-3-5-8(12)10(14)13-7-4-6-9(13)11(15)16/h8-9,15-16H,2-7,12H2,1H3/t8-,9+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2n/an/an/an/an/an/a



ActivX Biosciences

Curated by ChEMBL


Assay Description
Inhibitory concentration against human dipeptidylpeptidase 7


Bioorg Med Chem Lett 15: 4256-60 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.076
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146975
PNG
(2-(S)-Amino-4-benzylamino-1-piperidin-1-yl-butan-1...)
Show SMILES N[C@@H](CCNCc1ccccc1)C(=O)N1CCCCC1
Show InChI InChI=1S/C16H25N3O/c17-15(16(20)19-11-5-2-6-12-19)9-10-18-13-14-7-3-1-4-8-14/h1,3-4,7-8,15,18H,2,5-6,9-13,17H2/t15-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.03n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50171645
PNG
(2-Cyclodecylamino-1-pyrrolidin-1-yl--2-borandihydr...)
Show SMILES OB(O)[C@@H]1CCCN1C(=O)CNC1CCCCCCCCC1
Show InChI InChI=1S/C16H31BN2O3/c20-16(19-12-8-11-15(19)17(21)22)13-18-14-9-6-4-2-1-3-5-7-10-14/h14-15,18,21-22H,1-13H2/t15-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.20n/an/an/an/an/an/a



ActivX Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against human DPP7 using Ala-Pro-AMC in fluorometric assay


Bioorg Med Chem Lett 15: 4239-42 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.075
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146979
PNG
((S)-2-Amino-4-(4-chloro-benzylamino)-1-(2-methyl-p...)
Show SMILES CC1CCCCN1C(=O)[C@@H](N)CCNCc1ccc(Cl)cc1
Show InChI InChI=1S/C17H26ClN3O/c1-13-4-2-3-11-21(13)17(22)16(19)9-10-20-12-14-5-7-15(18)8-6-14/h5-8,13,16,20H,2-4,9-12,19H2,1H3/t13?,16-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.30n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146969
PNG
(3-[((S)-3-Amino-4-oxo-4-piperidin-1-yl-butylamino)...)
Show SMILES N[C@@H](CCNCc1cccc(c1)C#N)C(=O)N1CCCCC1
Show InChI InChI=1S/C17H24N4O/c18-12-14-5-4-6-15(11-14)13-20-8-7-16(19)17(22)21-9-2-1-3-10-21/h4-6,11,16,20H,1-3,7-10,13,19H2/t16-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.70n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50221977
PNG
((2S,3S)-2-amino-3-(4'-fluoro-biphenyl-4-yl)-1-((S)...)
Show SMILES C[C@H]([C@H](N)C(=O)N1CC[C@H](F)C1)c1ccc(cc1)-c1ccc(F)cc1 |r|
Show InChI InChI=1S/C20H22F2N2O/c1-13(19(23)20(25)24-11-10-18(22)12-24)14-2-4-15(5-3-14)16-6-8-17(21)9-7-16/h2-9,13,18-19H,10-12,23H2,1H3/t13-,18-,19-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 2.70n/an/an/an/an/an/a



Matrix Laboratories Limited

Curated by ChEMBL


Assay Description
Inhibition of QPP


Bioorg Med Chem 17: 1783-802 (2009)


Article DOI: 10.1016/j.bmc.2009.01.061
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146981
PNG
(2-(S)-Amino-4-(2,4-dimethoxy-benzylamino)-1-piperi...)
Show SMILES COc1ccc(CNCC[C@H](N)C(=O)N2CCCCC2)c(OC)c1
Show InChI InChI=1S/C18H29N3O3/c1-23-15-7-6-14(17(12-15)24-2)13-20-9-8-16(19)18(22)21-10-4-3-5-11-21/h6-7,12,16,20H,3-5,8-11,13,19H2,1-2H3/t16-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.70n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50191170
PNG
((2S,4S)-4-(4-chlorobenzylamino)-2-amino-1-(piperid...)
Show SMILES CC[C@@H](C[C@H](N)C(=O)N1CCCCC1)NCc1ccc(Cl)cc1
Show InChI InChI=1S/C18H28ClN3O/c1-2-16(21-13-14-6-8-15(19)9-7-14)12-17(20)18(23)22-10-4-3-5-11-22/h6-9,16-17,21H,2-5,10-13,20H2,1H3/t16-,17-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.40n/an/an/an/an/an/a



Laboratory of Medicinal Chemistry University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2


Bioorg Med Chem Lett 16: 4777-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.082
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50171558
PNG
(2,6-Diamino-hexanoic acid ((R)-1-boron-dihydroxide...)
Show SMILES CCCC[C@@H](NC(=O)[C@@H](N)CCCCN)B(O)O
Show InChI InChI=1S/C11H26BN3O3/c1-2-3-7-10(12(17)18)15-11(16)9(14)6-4-5-8-13/h9-10,17-18H,2-8,13-14H2,1H3,(H,15,16)/t9-,10+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.70n/an/an/an/an/an/a



ActivX Biosciences

Curated by ChEMBL


Assay Description
Inhibitory concentration against human dipeptidylpeptidase 7


Bioorg Med Chem Lett 15: 4256-60 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.076
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50191164
PNG
((2S,4S)-4-(4-chlorobenzylamino)-2-amino-5-phenyl-1...)
Show SMILES N[C@@H](C[C@H](Cc1ccccc1)NCc1ccc(Cl)cc1)C(=O)N1CCCCC1
Show InChI InChI=1S/C23H30ClN3O/c24-20-11-9-19(10-12-20)17-26-21(15-18-7-3-1-4-8-18)16-22(25)23(28)27-13-5-2-6-14-27/h1,3-4,7-12,21-22,26H,2,5-6,13-17,25H2/t21-,22-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.80n/an/an/an/an/an/a



Laboratory of Medicinal Chemistry University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of DPP2


Bioorg Med Chem Lett 16: 4777-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.06.082
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146958
PNG
(1-((S)-2-Amino-4-benzylamino-butyryl)-piperidine-2...)
Show SMILES N[C@@H](CCNCc1ccccc1)C(=O)N1CCCCC1C#N
Show InChI InChI=1S/C17H24N4O/c18-12-15-8-4-5-11-21(15)17(22)16(19)9-10-20-13-14-6-2-1-3-7-14/h1-3,6-7,15-16,20H,4-5,8-11,13,19H2/t15?,16-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50171650
PNG
(2-Cyclooctonylamino-1-pyrrolidin-1-yl--2-borandihy...)
Show SMILES OB(O)[C@@H]1CCCN1C(=O)CNC1CCCCCCC1
Show InChI InChI=1S/C14H27BN2O3/c18-14(17-10-6-9-13(17)15(19)20)11-16-12-7-4-2-1-3-5-8-12/h12-13,16,19-20H,1-11H2/t13-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4n/an/an/an/an/an/a



ActivX Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against human DPP7 using Ala-Pro-AMC in fluorometric assay


Bioorg Med Chem Lett 15: 4239-42 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.075
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50171656
PNG
(2-Cyclohexylamino-1-pyrrolidin-1-yl--2-borandihydr...)
Show SMILES OB(O)[C@@H]1CCCN1C(=O)CNC1CCCCC1
Show InChI InChI=1S/C12H23BN2O3/c16-12(9-14-10-5-2-1-3-6-10)15-8-4-7-11(15)13(17)18/h10-11,14,17-18H,1-9H2/t11-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 4.10n/an/an/an/an/an/a



ActivX Biosciences, Inc.

Curated by ChEMBL


Assay Description
Inhibitory activity against human DPP7 using Ala-Pro-AMC in fluorometric assay


Bioorg Med Chem Lett 15: 4239-42 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.075
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146982
PNG
((S)-2-Amino-4-[bis-(4-chloro-benzyl)-amino]-1-pipe...)
Show SMILES N[C@@H](CCN(Cc1ccc(Cl)cc1)Cc1ccc(Cl)cc1)C(=O)N1CCCCC1
Show InChI InChI=1S/C23H29Cl2N3O/c24-20-8-4-18(5-9-20)16-27(17-19-6-10-21(25)11-7-19)15-12-22(26)23(29)28-13-2-1-3-14-28/h4-11,22H,1-3,12-17,26H2/t22-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.20n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146963
PNG
(6-((S)-3-Amino-4-oxo-4-piperidin-1-yl-butylamino)-...)
Show SMILES N[C@@H](CCNc1ccc(cn1)C#N)C(=O)N1CCCCC1
Show InChI InChI=1S/C15H21N5O/c16-10-12-4-5-14(19-11-12)18-7-6-13(17)15(21)20-8-2-1-3-9-20/h4-5,11,13H,1-3,6-9,17H2,(H,18,19)/t13-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.60n/an/an/an/an/an/a



University of Antwerp

Curated by ChEMBL


Assay Description
Inhibition of human Dipeptidyl-peptidase II (DPP II)


J Med Chem 47: 2906-16 (2004)


Article DOI: 10.1021/jm031122f
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50171553
PNG
(2,5-Diamino-pentanoic acid ((R)-1-boron-dihydroxid...)
Show SMILES CCCC[C@@H](NC(=O)[C@@H](N)CCCN)B(O)O
Show InChI InChI=1S/C10H24BN3O3/c1-2-3-6-9(11(16)17)14-10(15)8(13)5-4-7-12/h8-9,16-17H,2-7,12-13H2,1H3,(H,14,15)/t8-,9+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.70n/an/an/an/an/an/a



ActivX Biosciences

Curated by ChEMBL


Assay Description
Inhibitory concentration against human dipeptidylpeptidase 7


Bioorg Med Chem Lett 15: 4256-60 (2005)


Article DOI: 10.1016/j.bmcl.2005.06.076
More data for this
Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II)


(Homo sapiens (Human))
BDBM50146971
PNG
(2-(S)-Amino-4-(2-chloro-benzylamino)-1-piperidin-1...)
Show SMILES N[C@@H](CCNCc1ccccc1Cl)C(=O)N1CCCCC1
Show InChI InChI=1S/C16H24ClN3O/c17-14-7-3-2-6-13(14)12-19-9-8-15(18)16(21)20-10-4-1-5-11-20/h2-3,6-7,15,19H,1,4-5,8-12,18H2/t15-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



National Health Research Institutes

Curated by ChEMBL


Assay Description
Inhibition of human recombinant His-tagged DPP2 expressed in insect cells


J Med Chem 53: 6572-83 (2010)


Article DOI: 10.1021/jm1002556
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 1696 total )  |  Next  |  Last  >>
Jump to: