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Compile Data Set for Download or QSAR

Found 3 hits of ki data for polymerid = 5565   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50410390
PNG
(CHEMBL1161754)
Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CP(O)(=O)OP(O)(=O)OP(O)(O)O)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C10H18N5O12P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(25-10)1-28(18,19)26-30(23,24)27-29(20,21)22/h2-4,6-7,10,16-17,20-22,29H,1H2,(H,18,19)(H,23,24)(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.01E+5n/an/an/an/an/an/an/an/a



Valeant Pharmaceuticals International

Curated by ChEMBL


Assay Description
Inhibition constant against ATP binding towards Hepatitis C Virus NS5BRdRp


J Med Chem 48: 2867-75 (2005)


Article DOI: 10.1021/jm049029u
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50410391
PNG
(CHEMBL1161753)
Show SMILES Nc1ncnc2n(cnc12)[C@@H]1C[C@H](OCP(O)(=O)OP(O)(=O)OP(O)(O)O)[C@@H](O)[C@H]1O |r|
Show InChI InChI=1S/C11H20N5O12P3/c12-10-7-11(14-2-13-10)16(3-15-7)5-1-6(9(18)8(5)17)26-4-29(19,20)27-31(24,25)28-30(21,22)23/h2-3,5-6,8-9,17-18,21-23,30H,1,4H2,(H,19,20)(H,24,25)(H2,12,13,14)/t5-,6+,8+,9-/m1/s1
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.29E+5n/an/an/an/an/an/an/an/a



Valeant Pharmaceuticals International

Curated by ChEMBL


Assay Description
Inhibition constant against ATP binding towards Hepatitis C Virus NS5BRdRp


J Med Chem 48: 2867-75 (2005)


Article DOI: 10.1021/jm049029u
More data for this
Ligand-Target Pair
Hepatitis C virus NS5B RNA-dependent RNA polymerase


(Hepatitis C virus)
BDBM50410392
PNG
(CHEMBL1161773)
Show SMILES C[C@@]1(O)[C@H](O)[C@@H](CCP(O)(=O)OP(O)(=O)OP(O)(O)O)O[C@H]1n1cnc2c(N)ncnc12 |r|
Show InChI InChI=1S/C12H22N5O12P3/c1-12(19)8(18)6(2-3-30(20,21)28-32(25,26)29-31(22,23)24)27-11(12)17-5-16-7-9(13)14-4-15-10(7)17/h4-6,8,11,18-19,22-24,31H,2-3H2,1H3,(H,20,21)(H,25,26)(H2,13,14,15)/t6-,8-,11-,12-/m1/s1
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
3.27E+5n/an/an/an/an/an/an/an/a



Valeant Pharmaceuticals International

Curated by ChEMBL


Assay Description
Inhibition constant against ATP binding towards Hepatitis C Virus NS5BRdRp


J Med Chem 48: 2867-75 (2005)


Article DOI: 10.1021/jm049029u
More data for this
Ligand-Target Pair