Found 53 hits of kd data for polymerid = 5598 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50307387
(8-(4-Phenyl[1,2,3]triazol-1-yl)octyl 2,3,4,6-Tetra...)Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](O[C@@H]2[C@@H](OCCCCCCCCn3cc(nn3)-c3ccccc3)O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C46H73N3O74S16/c50-124(51,52)99-15-22-27(113-129(65,66)67)32(109-44-39(121-137(89,90)91)33(28(114-130(68,69)70)23(106-44)16-100-125(53,54)55)111-46-41(123-139(95,96)97)36(119-135(83,84)85)31(117-133(77,78)79)26(108-46)19-103-128(62,63)64)38(120-136(86,87)88)43(105-22)110-34-29(115-131(71,72)73)24(17-101-126(56,57)58)107-45(40(34)122-138(92,93)94)112-37-35(118-134(80,81)82)30(116-132(74,75)76)25(18-102-127(59,60)61)104-42(37)98-13-9-4-2-1-3-8-12-49-14-21(47-48-49)20-10-6-5-7-11-20/h5-7,10-11,14,22-46H,1-4,8-9,12-13,15-19H2,(H,50,51,52)(H,53,54,55)(H,56,57,58)(H,59,60,61)(H,62,63,64)(H,65,66,67)(H,68,69,70)(H,71,72,73)(H,74,75,76)(H,77,78,79)(H,80,81,82)(H,83,84,85)(H,86,87,88)(H,89,90,91)(H,92,93,94)(H,95,96,97)/p-16/t22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32+,33+,34+,35+,36+,37+,38+,39+,40+,41+,42+,43-,44-,45-,46-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 0.620 | n/a | n/a | n/a | n/a | n/a |
Progen Pharmaceuticals Limited
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon-based solution affinity assay |
J Med Chem 53: 1686-99 (2010)
Article DOI: 10.1021/jm901449m
BindingDB Entry DOI: 10.7270/Q2PG1SPH |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50307389
(2,3,4,6-Tetra-O-sulfo-alpha-D-mannopyranosyl-(1->3...)Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](OCCCCCCCCn2cc(nn2)-c2cccc3ccccc23)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]5O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]5OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C50H75N3O74S16/c54-128(55,56)103-17-26-31(117-133(69,70)71)36(113-48-43(125-141(93,94)95)37(32(118-134(72,73)74)27(110-48)18-104-129(57,58)59)115-50-45(127-143(99,100)101)40(123-139(87,88)89)35(121-137(81,82)83)30(112-50)21-107-132(66,67)68)42(124-140(90,91)92)47(109-26)114-38-33(119-135(75,76)77)28(19-105-130(60,61)62)111-49(44(38)126-142(96,97)98)116-41-39(122-138(84,85)86)34(120-136(78,79)80)29(20-106-131(63,64)65)108-46(41)102-15-8-4-2-1-3-7-14-53-16-25(51-52-53)24-13-9-11-22-10-5-6-12-23(22)24/h5-6,9-13,16,26-50H,1-4,7-8,14-15,17-21H2,(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)(H,81,82,83)(H,84,85,86)(H,87,88,89)(H,90,91,92)(H,93,94,95)(H,96,97,98)(H,99,100,101)/p-16/t26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36+,37+,38+,39+,40+,41+,42+,43+,44+,45+,46+,47-,48-,49-,50-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 0.700 | n/a | n/a | n/a | n/a | n/a |
Progen Pharmaceuticals Limited
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon-based solution affinity assay |
J Med Chem 53: 1686-99 (2010)
Article DOI: 10.1021/jm901449m
BindingDB Entry DOI: 10.7270/Q2PG1SPH |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50307396
(12-(4-Naphthalen-1-yl[1,2,3]triazol-1-yl)dodecyl 2...)Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](OCCCCCCCCCCCCn2cc(nn2)-c2cccc3ccccc23)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]5O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]5OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C54H83N3O74S16/c58-132(59,60)107-21-30-35(121-137(73,74)75)40(117-52-47(129-145(97,98)99)41(36(122-138(76,77)78)31(114-52)22-108-133(61,62)63)119-54-49(131-147(103,104)105)44(127-143(91,92)93)39(125-141(85,86)87)34(116-54)25-111-136(70,71)72)46(128-144(94,95)96)51(113-30)118-42-37(123-139(79,80)81)32(23-109-134(64,65)66)115-53(48(42)130-146(100,101)102)120-45-43(126-142(88,89)90)38(124-140(82,83)84)33(24-110-135(67,68)69)112-50(45)106-19-12-8-6-4-2-1-3-5-7-11-18-57-20-29(55-56-57)28-17-13-15-26-14-9-10-16-27(26)28/h9-10,13-17,20,30-54H,1-8,11-12,18-19,21-25H2,(H,58,59,60)(H,61,62,63)(H,64,65,66)(H,67,68,69)(H,70,71,72)(H,73,74,75)(H,76,77,78)(H,79,80,81)(H,82,83,84)(H,85,86,87)(H,88,89,90)(H,91,92,93)(H,94,95,96)(H,97,98,99)(H,100,101,102)(H,103,104,105)/p-16/t30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40+,41+,42+,43+,44+,45+,46+,47+,48+,49+,50+,51-,52-,53-,54-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 0.790 | n/a | n/a | n/a | n/a | n/a |
Progen Pharmaceuticals Limited
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon-based solution affinity assay |
J Med Chem 53: 1686-99 (2010)
Article DOI: 10.1021/jm901449m
BindingDB Entry DOI: 10.7270/Q2PG1SPH |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50307392
(3-(4-Phenyl[1,2,3]triazol-1-yl)propyl 2,3,4,6-Tetr...)Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](OCCCn2cc(nn2)-c2ccccc2)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]5O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]5OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C41H63N3O74S16/c45-119(46,47)94-10-17-22(108-124(60,61)62)27(104-39-34(116-132(84,85)86)28(23(109-125(63,64)65)18(101-39)11-95-120(48,49)50)106-41-36(118-134(90,91)92)31(114-130(78,79)80)26(112-128(72,73)74)21(103-41)14-98-123(57,58)59)33(115-131(81,82)83)38(100-17)105-29-24(110-126(66,67)68)19(12-96-121(51,52)53)102-40(35(29)117-133(87,88)89)107-32-30(113-129(75,76)77)25(111-127(69,70)71)20(13-97-122(54,55)56)99-37(32)93-8-4-7-44-9-16(42-43-44)15-5-2-1-3-6-15/h1-3,5-6,9,17-41H,4,7-8,10-14H2,(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)(H,81,82,83)(H,84,85,86)(H,87,88,89)(H,90,91,92)/p-16/t17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27+,28+,29+,30+,31+,32+,33+,34+,35+,36+,37+,38-,39-,40-,41-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a |
Progen Pharmaceuticals Limited
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon-based solution affinity assay |
J Med Chem 53: 1686-99 (2010)
Article DOI: 10.1021/jm901449m
BindingDB Entry DOI: 10.7270/Q2PG1SPH |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50307400
(CHEMBL604366 | hexadecasodium [3-({4-[(4-{[3,5-bis...)Show SMILES CCCCCCCCO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C38H68O74S16/c1-2-3-4-5-6-7-8-87-34-29(27(107-123(69,70)71)22(105-121(63,64)65)17(93-34)12-91-116(48,49)50)101-37-32(111-127(81,82)83)26(21(104-120(60,61)62)16(96-37)11-90-115(45,46)47)99-35-30(109-125(75,76)77)24(19(102-118(54,55)56)14(94-35)9-88-113(39,40)41)98-36-31(110-126(78,79)80)25(20(103-119(57,58)59)15(95-36)10-89-114(42,43)44)100-38-33(112-128(84,85)86)28(108-124(72,73)74)23(106-122(66,67)68)18(97-38)13-92-117(51,52)53/h14-38H,2-13H2,1H3,(H,39,40,41)(H,42,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)(H,81,82,83)(H,84,85,86)/p-16/t14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24+,25+,26+,27+,28+,29+,30+,31+,32+,33+,34+,35-,36-,37-,38-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a |
Progen Pharmaceuticals Limited
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon-based solution affinity assay |
J Med Chem 53: 1686-99 (2010)
Article DOI: 10.1021/jm901449m
BindingDB Entry DOI: 10.7270/Q2PG1SPH |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50179254
((2R,3S,4S,5S,6R)-2-{[(2R,3S,4S,5R,6R)-2-{[(2R,3S,4...)Show SMILES OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](CO)O[C@H](O[C@H]3[C@H](O)[C@@H](CO)O[C@H](O[C@H]4[C@H](O)[C@@H](CO)O[C@H](O[C@H]5[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]5OCc5ccccc5)[C@H]4O)[C@H]3O)[C@H]2O)[C@@H](O)[C@@H](O)[C@@H]1O Show InChI InChI=1S/C37H58O26/c38-6-13-18(43)23(48)25(50)33(55-13)60-29-20(45)15(8-40)56-34(26(29)51)61-30-21(46)16(9-41)57-35(27(30)52)62-31-22(47)17(10-42)58-36(28(31)53)63-32-24(49)19(44)14(7-39)59-37(32)54-11-12-4-2-1-3-5-12/h1-5,13-53H,6-11H2/t13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+,24+,25+,26+,27+,28+,29+,30+,31+,32+,33-,34-,35-,36-,37+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a |
Progen Industries Limited
Curated by ChEMBL
| Assay Description
Binding affinity for VEGF by BIAcore solution affinity assay |
J Med Chem 48: 8229-36 (2005)
Article DOI: 10.1021/jm050618p
BindingDB Entry DOI: 10.7270/Q2MG7P2V |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50179253
((2R,3S,4S,5S,6R)-2-{[(2R,3S,4S,5R,6R)-2-{[(2R,3S,4...)Show SMILES CCCCCCCCO[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]4O)[C@@H]3O)[C@@H]2O)[C@@H]1O Show InChI InChI=1S/C38H68O26/c1-2-3-4-5-6-7-8-55-38-33(25(50)20(45)15(10-40)60-38)64-37-29(54)32(23(48)18(13-43)59-37)63-36-28(53)31(22(47)17(12-42)58-36)62-35-27(52)30(21(46)16(11-41)57-35)61-34-26(51)24(49)19(44)14(9-39)56-34/h14-54H,2-13H2,1H3/t14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24+,25+,26+,27+,28+,29+,30+,31+,32+,33+,34-,35-,36-,37-,38+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a |
Progen Industries Limited
Curated by ChEMBL
| Assay Description
Binding affinity for VEGF by BIAcore solution affinity assay |
J Med Chem 48: 8229-36 (2005)
Article DOI: 10.1021/jm050618p
BindingDB Entry DOI: 10.7270/Q2MG7P2V |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50307398
(CHEMBL603122 | Hexadecasodium [2-(benzyloxy)-3-({4...)Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](OCc2ccccc2)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]5O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]5OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C37H58O74S16/c38-112(39,40)87-7-13-18(101-117(53,54)55)23(97-35-30(109-125(77,78)79)24(19(102-118(56,57)58)14(94-35)8-88-113(41,42)43)99-37-32(111-127(83,84)85)27(107-123(71,72)73)22(105-121(65,66)67)17(96-37)11-91-116(50,51)52)29(108-124(74,75)76)34(93-13)98-25-20(103-119(59,60)61)15(9-89-114(44,45)46)95-36(31(25)110-126(80,81)82)100-28-26(106-122(68,69)70)21(104-120(62,63)64)16(10-90-115(47,48)49)92-33(28)86-6-12-4-2-1-3-5-12/h1-5,13-37H,6-11H2,(H,38,39,40)(H,41,42,43)(H,44,45,46)(H,47,48,49)(H,50,51,52)(H,53,54,55)(H,56,57,58)(H,59,60,61)(H,62,63,64)(H,65,66,67)(H,68,69,70)(H,71,72,73)(H,74,75,76)(H,77,78,79)(H,80,81,82)(H,83,84,85)/p-16/t13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+,24+,25+,26+,27+,28+,29+,30+,31+,32+,33+,34-,35-,36-,37-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.80 | n/a | n/a | n/a | n/a | n/a |
Progen Pharmaceuticals Limited
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon-based solution affinity assay |
J Med Chem 53: 1686-99 (2010)
Article DOI: 10.1021/jm901449m
BindingDB Entry DOI: 10.7270/Q2PG1SPH |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50378647
(CHEMBL1627122 | PI-88)Show SMILES [O-]P([O-])(=O)OC[C@H]1O[C@H](O[C@H]2[C@H](OS([O-])(=O)=O)[C@@H](COS([O-])(=O)=O)O[C@H](O[C@H]3[C@H](OS([O-])(=O)=O)[C@@H](COS([O-])(=O)=O)O[C@H](O[C@H]4[C@H](OS([O-])(=O)=O)[C@@H](COS([O-])(=O)=O)O[C@H](O[C@@H]5[C@@H](OS([O-])(=O)=O)O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]5OS([O-])(=O)=O)[C@H]4OS([O-])(=O)=O)[C@H]3OS([O-])(=O)=O)[C@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C30H53O77PS16/c31-108(32,33)82-1-6-14(99-116(55,56)57)20(102-119(64,65)66)25(106-123(76,77)78)29(87-6)94-17-12(97-114(49,50)51)8(3-84-110(37,38)39)89-27(23(17)104-121(70,71)72)92-16-11(96-113(46,47)48)7(2-83-109(34,35)36)88-26(22(16)103-120(67,68)69)93-18-13(98-115(52,53)54)9(4-85-111(40,41)42)90-28(24(18)105-122(73,74)75)95-21-19(101-118(61,62)63)15(100-117(58,59)60)10(5-86-112(43,44)45)91-30(21)107-124(79,80)81/h6-30H,1-5H2,(H2,31,32,33)(H,34,35,36)(H,37,38,39)(H,40,41,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60)(H,61,62,63)(H,64,65,66)(H,67,68,69)(H,70,71,72)(H,73,74,75)(H,76,77,78)(H,79,80,81)/p-18/t6-,7-,8-,9-,10-,11-,12-,13-,14-,15-,16+,17+,18+,19+,20+,21+,22+,23+,24+,25+,26-,27-,28-,29-,30-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a | n/a |
Progen Pharmaceuticals Limited
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon-based solution affinity assay |
J Med Chem 53: 1686-99 (2010)
Article DOI: 10.1021/jm901449m
BindingDB Entry DOI: 10.7270/Q2PG1SPH |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50307395
(12-(4-Phenyl[1,2,3]triazol-1-yl)dodecyl 2,3,4,6-Te...)Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](O[C@@H]2[C@@H](OCCCCCCCCCCCCn3cc(nn3)-c3ccccc3)O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C50H81N3O74S16/c54-128(55,56)103-19-26-31(117-133(69,70)71)36(113-48-43(125-141(93,94)95)37(32(118-134(72,73)74)27(110-48)20-104-129(57,58)59)115-50-45(127-143(99,100)101)40(123-139(87,88)89)35(121-137(81,82)83)30(112-50)23-107-132(66,67)68)42(124-140(90,91)92)47(109-26)114-38-33(119-135(75,76)77)28(21-105-130(60,61)62)111-49(44(38)126-142(96,97)98)116-41-39(122-138(84,85)86)34(120-136(78,79)80)29(22-106-131(63,64)65)108-46(41)102-17-13-8-6-4-2-1-3-5-7-12-16-53-18-25(51-52-53)24-14-10-9-11-15-24/h9-11,14-15,18,26-50H,1-8,12-13,16-17,19-23H2,(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)(H,81,82,83)(H,84,85,86)(H,87,88,89)(H,90,91,92)(H,93,94,95)(H,96,97,98)(H,99,100,101)/p-16/t26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36+,37+,38+,39+,40+,41+,42+,43+,44+,45+,46+,47-,48-,49-,50-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.10 | n/a | n/a | n/a | n/a | n/a |
Progen Pharmaceuticals Limited
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon-based solution affinity assay |
J Med Chem 53: 1686-99 (2010)
Article DOI: 10.1021/jm901449m
BindingDB Entry DOI: 10.7270/Q2PG1SPH |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50179255
(CHEMBL265885 | N-[(2S,3S,4S,5S,6R)-3-{[(2R,3S,4S,5...)Show SMILES OC[C@H]1O[C@H](NC(=O)COc2ccccc2)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O[C@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]5O)[C@@H]4O)[C@@H]3O)[C@@H]2O)[C@@H](O)[C@@H]1O Show InChI InChI=1S/C38H59NO27/c40-6-13-20(47)25(52)33(34(58-13)39-18(45)11-57-12-4-2-1-3-5-12)66-38-29(56)32(23(50)17(10-44)62-38)65-37-28(55)31(22(49)16(9-43)61-37)64-36-27(54)30(21(48)15(8-42)60-36)63-35-26(53)24(51)19(46)14(7-41)59-35/h1-5,13-17,19-38,40-44,46-56H,6-11H2,(H,39,45)/t13-,14-,15-,16-,17-,19-,20-,21-,22-,23-,24+,25+,26+,27+,28+,29+,30+,31+,32+,33+,34+,35-,36-,37-,38-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a |
Progen Industries Limited
Curated by ChEMBL
| Assay Description
Binding affinity for VEGF by BIAcore solution affinity assay |
J Med Chem 48: 8229-36 (2005)
Article DOI: 10.1021/jm050618p
BindingDB Entry DOI: 10.7270/Q2MG7P2V |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50307390
(8-(4-Naphthalen-1-yl[1,2,3]triazol-1-yl)octyl 2,3,...)Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](OCCCCCCCCn2cc(nn2)-c2cccc3ccccc23)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C44H65N3O60S13/c48-108(49,50)88-17-25-29(99-112(60,61)62)33(97-44-40(107-120(84,85)86)36(104-117(75,76)77)32(102-115(69,70)71)28(95-44)20-91-111(57,58)59)38(105-118(78,79)80)42(93-25)96-34-30(100-113(63,64)65)26(18-89-109(51,52)53)94-43(39(34)106-119(81,82)83)98-37-35(103-116(72,73)74)31(101-114(66,67)68)27(19-90-110(54,55)56)92-41(37)87-15-8-4-2-1-3-7-14-47-16-24(45-46-47)23-13-9-11-21-10-5-6-12-22(21)23/h5-6,9-13,16,25-44H,1-4,7-8,14-15,17-20H2,(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)(H,78,79,80)(H,81,82,83)(H,84,85,86)/p-13/t25-,26-,27-,28-,29-,30-,31-,32-,33+,34+,35+,36+,37+,38+,39+,40+,41+,42-,43-,44-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.10 | n/a | n/a | n/a | n/a | n/a |
Progen Pharmaceuticals Limited
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon-based solution affinity assay |
J Med Chem 53: 1686-99 (2010)
Article DOI: 10.1021/jm901449m
BindingDB Entry DOI: 10.7270/Q2PG1SPH |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50179256
(6-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d...)Show SMILES OC[C@H]1O[C@H](NC(=O)CCCCCNC(=O)CCCC[C@@H]2SC[C@@H]3NC(=O)N[C@H]23)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O[C@H]4O[C@H](CO)[C@@H](O)[C@H](O[C@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]5O)[C@@H]4O)[C@@H]3O)[C@@H]2O)[C@@H](O)[C@@H]1O Show InChI InChI=1S/C46H78N4O28S/c51-10-17-27(59)32(64)40(41(70-17)49-24(57)8-2-1-5-9-47-23(56)7-4-3-6-22-25-16(15-79-22)48-46(69)50-25)78-45-36(68)39(30(62)21(14-55)74-45)77-44-35(67)38(29(61)20(13-54)73-44)76-43-34(66)37(28(60)19(12-53)72-43)75-42-33(65)31(63)26(58)18(11-52)71-42/h16-22,25-45,51-55,58-68H,1-15H2,(H,47,56)(H,49,57)(H2,48,50,69)/t16-,17+,18+,19+,20+,21+,22-,25-,26+,27+,28+,29+,30+,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42+,43+,44+,45+/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | 7.20 | n/a | n/a | n/a | n/a | n/a |
Progen Industries Limited
Curated by ChEMBL
| Assay Description
Binding affinity for VEGF by BIAcore solution affinity assay |
J Med Chem 48: 8229-36 (2005)
Article DOI: 10.1021/jm050618p
BindingDB Entry DOI: 10.7270/Q2MG7P2V |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50307391
(8-(5-Dimethylaminonaphthalene-1-sulfonamido)octyl ...)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCCCCCCO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C44H70N2O62S14/c1-46(2)23-13-9-12-22-21(23)11-10-14-28(22)109(47,48)45-15-7-5-3-4-6-8-16-88-41-37(35(104-118(73,74)75)31(102-116(67,68)69)26(93-41)19-91-112(55,56)57)99-43-39(107-121(82,83)84)34(30(101-115(64,65)66)25(95-43)18-90-111(52,53)54)97-42-38(106-120(79,80)81)33(29(100-114(61,62)63)24(94-42)17-89-110(49,50)51)98-44-40(108-122(85,86)87)36(105-119(76,77)78)32(103-117(70,71)72)27(96-44)20-92-113(58,59)60/h9-14,24-27,29-45H,3-8,15-20H2,1-2H3,(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60)(H,61,62,63)(H,64,65,66)(H,67,68,69)(H,70,71,72)(H,73,74,75)(H,76,77,78)(H,79,80,81)(H,82,83,84)(H,85,86,87)/p-13/t24-,25-,26-,27-,29-,30-,31-,32-,33+,34+,35+,36+,37+,38+,39+,40+,41+,42-,43-,44-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | n/a |
Progen Pharmaceuticals Limited
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon-based solution affinity assay |
J Med Chem 53: 1686-99 (2010)
Article DOI: 10.1021/jm901449m
BindingDB Entry DOI: 10.7270/Q2PG1SPH |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50307388
(8-(4-Phenyl[1,2,3]triazol-1-yl)octyl 2,3,4,6-Tetra...)Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](O[C@@H]2[C@@H](OCCCCCCCCn3cc(nn3)-c3ccccc3)O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C40H63N3O60S13/c44-104(45,46)84-15-21-25(95-108(56,57)58)29(93-40-36(103-116(80,81)82)32(100-113(71,72)73)28(98-111(65,66)67)24(91-40)18-87-107(53,54)55)34(101-114(74,75)76)38(89-21)92-30-26(96-109(59,60)61)22(16-85-105(47,48)49)90-39(35(30)102-115(77,78)79)94-33-31(99-112(68,69)70)27(97-110(62,63)64)23(17-86-106(50,51)52)88-37(33)83-13-9-4-2-1-3-8-12-43-14-20(41-42-43)19-10-6-5-7-11-19/h5-7,10-11,14,21-40H,1-4,8-9,12-13,15-18H2,(H,44,45,46)(H,47,48,49)(H,50,51,52)(H,53,54,55)(H,56,57,58)(H,59,60,61)(H,62,63,64)(H,65,66,67)(H,68,69,70)(H,71,72,73)(H,74,75,76)(H,77,78,79)(H,80,81,82)/p-13/t21-,22-,23-,24-,25-,26-,27-,28-,29+,30+,31+,32+,33+,34+,35+,36+,37+,38-,39-,40-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 10.4 | n/a | n/a | n/a | n/a | n/a |
Progen Pharmaceuticals Limited
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon-based solution affinity assay |
J Med Chem 53: 1686-99 (2010)
Article DOI: 10.1021/jm901449m
BindingDB Entry DOI: 10.7270/Q2PG1SPH |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50307386
(CHEMBL604367 | Dodecyl 2,3,4,6-Tetra-O-sulfo-alpha...)Show SMILES CCCCCCCCCCCCO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C42H76O74S16/c1-2-3-4-5-6-7-8-9-10-11-12-91-38-33(31(111-127(73,74)75)26(109-125(67,68)69)21(97-38)16-95-120(52,53)54)105-41-36(115-131(85,86)87)30(25(108-124(64,65)66)20(100-41)15-94-119(49,50)51)103-39-34(113-129(79,80)81)28(23(106-122(58,59)60)18(98-39)13-92-117(43,44)45)102-40-35(114-130(82,83)84)29(24(107-123(61,62)63)19(99-40)14-93-118(46,47)48)104-42-37(116-132(88,89)90)32(112-128(76,77)78)27(110-126(70,71)72)22(101-42)17-96-121(55,56)57/h18-42H,2-17H2,1H3,(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60)(H,61,62,63)(H,64,65,66)(H,67,68,69)(H,70,71,72)(H,73,74,75)(H,76,77,78)(H,79,80,81)(H,82,83,84)(H,85,86,87)(H,88,89,90)/p-16/t18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28+,29+,30+,31+,32+,33+,34+,35+,36+,37+,38+,39-,40-,41-,42-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a |
Progen Pharmaceuticals Limited
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon-based solution affinity assay |
J Med Chem 53: 1686-99 (2010)
Article DOI: 10.1021/jm901449m
BindingDB Entry DOI: 10.7270/Q2PG1SPH |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50307402
(4-Butylbenzyl 2,3,4,6-Tetra-O-sulfo-alpha-D-mannop...)Show SMILES CCCCc1ccc(CO[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]2O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)cc1 |r| Show InChI InChI=1S/C35H56O60S13/c1-2-3-4-14-5-7-15(8-6-14)9-75-32-28(26(91-104(60,61)62)22(89-102(54,55)56)18(80-32)12-78-98(42,43)44)86-34-30(94-107(69,70)71)25(21(88-101(51,52)53)17(82-34)11-77-97(39,40)41)84-33-29(93-106(66,67)68)24(20(87-100(48,49)50)16(81-33)10-76-96(36,37)38)85-35-31(95-108(72,73)74)27(92-105(63,64)65)23(90-103(57,58)59)19(83-35)13-79-99(45,46)47/h5-8,16-35H,2-4,9-13H2,1H3,(H,36,37,38)(H,39,40,41)(H,42,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)/p-13/t16-,17-,18-,19-,20-,21-,22-,23-,24+,25+,26+,27+,28+,29+,30+,31+,32+,33-,34-,35-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a |
Progen Pharmaceuticals Limited
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon-based solution affinity assay |
J Med Chem 53: 1686-99 (2010)
Article DOI: 10.1021/jm901449m
BindingDB Entry DOI: 10.7270/Q2PG1SPH |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50307394
(3-(5-Dimethylaminonaphthalene-1-sulfonamido)propyl...)Show SMILES CN(C)c1cccc2c(cccc12)S(=O)(=O)NCCCO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C45H70N2O76S17/c1-47(2)19-8-3-7-18-17(19)6-4-9-25(18)124(48,49)46-10-5-11-98-41-36(34(118-135(80,81)82)29(116-133(74,75)76)23(104-41)15-102-128(59,60)61)112-44-39(122-139(92,93)94)33(28(115-132(71,72)73)22(107-44)14-101-127(56,57)58)110-42-37(120-137(86,87)88)31(26(113-130(65,66)67)20(105-42)12-99-125(50,51)52)109-43-38(121-138(89,90)91)32(27(114-131(68,69)70)21(106-43)13-100-126(53,54)55)111-45-40(123-140(95,96)97)35(119-136(83,84)85)30(117-134(77,78)79)24(108-45)16-103-129(62,63)64/h3-4,6-9,20-24,26-46H,5,10-16H2,1-2H3,(H,50,51,52)(H,53,54,55)(H,56,57,58)(H,59,60,61)(H,62,63,64)(H,65,66,67)(H,68,69,70)(H,71,72,73)(H,74,75,76)(H,77,78,79)(H,80,81,82)(H,83,84,85)(H,86,87,88)(H,89,90,91)(H,92,93,94)(H,95,96,97)/p-16/t20-,21-,22-,23-,24-,26-,27-,28-,29-,30-,31+,32+,33+,34+,35+,36+,37+,38+,39+,40+,41+,42-,43-,44-,45-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 12.2 | n/a | n/a | n/a | n/a | n/a |
Progen Pharmaceuticals Limited
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon-based solution affinity assay |
J Med Chem 53: 1686-99 (2010)
Article DOI: 10.1021/jm901449m
BindingDB Entry DOI: 10.7270/Q2PG1SPH |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50428820
(CHEMBL2335722)Show SMILES O[C@H]1Cc2c(O)cc(O)c([C@@H]3C[C@H](Oc4cc(O)cc(O)c34)c3ccc(O)cc3)c2O[C@@H]1c1ccc(O)cc1 |r| Show InChI InChI=1S/C30H26O9/c31-16-5-1-14(2-6-16)25-12-20(27-22(35)9-18(33)10-26(27)38-25)28-23(36)13-21(34)19-11-24(37)29(39-30(19)28)15-3-7-17(32)8-4-15/h1-10,13,20,24-25,29,31-37H,11-12H2/t20-,24+,25+,29-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant VEGFA (unknown origin) measured for 60 seconds by surface plasmon resonance assay |
J Nat Prod 76: 29-35 (2013)
Article DOI: 10.1021/np300614u
BindingDB Entry DOI: 10.7270/Q24F1S3K |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50129952
(2-(3-(5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-c...)Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)c(-c3cc(ccc3O)-c3cc(O)c4c(cc(O)cc4=O)o3)c2o1 |(13.25,-26.01,;14.59,-25.24,;14.59,-23.7,;15.92,-22.93,;17.26,-23.7,;17.26,-25.24,;15.93,-26.01,;18.58,-22.93,;19.91,-23.69,;21.23,-22.92,;22.57,-23.69,;21.22,-21.4,;22.56,-20.64,;23.88,-21.41,;22.55,-19.1,;21.22,-18.33,;21.22,-16.79,;19.9,-19.11,;18.57,-18.34,;17.23,-19.1,;15.9,-18.33,;15.9,-16.79,;17.23,-16.02,;18.57,-16.79,;19.91,-16.02,;14.57,-19.09,;14.56,-20.65,;13.21,-21.42,;13.21,-22.96,;11.87,-20.64,;11.88,-19.08,;10.54,-18.32,;9.21,-19.09,;7.87,-18.32,;9.21,-20.64,;10.54,-21.41,;10.54,-22.95,;13.22,-18.3,;19.9,-20.64,;18.58,-21.4,)| Show InChI InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-33,35-37H | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant VEGFA (unknown origin) measured for 60 seconds by surface plasmon resonance assay |
J Nat Prod 76: 29-35 (2013)
Article DOI: 10.1021/np300614u
BindingDB Entry DOI: 10.7270/Q24F1S3K |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50307401
(CHEMBL602113 | Octyl 2,3,4,6-Tetra-O-sulfo-alpha-D...)Show SMILES CCCCCCCCO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C32H58O60S13/c1-2-3-4-5-6-7-8-72-29-25(23(88-101(57,58)59)19(86-99(51,52)53)15(77-29)11-75-95(39,40)41)83-31-27(91-104(66,67)68)22(18(85-98(48,49)50)14(79-31)10-74-94(36,37)38)81-30-26(90-103(63,64)65)21(17(84-97(45,46)47)13(78-30)9-73-93(33,34)35)82-32-28(92-105(69,70)71)24(89-102(60,61)62)20(87-100(54,55)56)16(80-32)12-76-96(42,43)44/h13-32H,2-12H2,1H3,(H,33,34,35)(H,36,37,38)(H,39,40,41)(H,42,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)/p-13/t13-,14-,15-,16-,17-,18-,19-,20-,21+,22+,23+,24+,25+,26+,27+,28+,29+,30-,31-,32-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a |
Progen Pharmaceuticals Limited
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon-based solution affinity assay |
J Med Chem 53: 1686-99 (2010)
Article DOI: 10.1021/jm901449m
BindingDB Entry DOI: 10.7270/Q2PG1SPH |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50307399
(Benzyl 2,3,4,6-Tetra-O-sulfo-alpha-D-mannopyranosy...)Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](OCc2ccccc2)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C31H48O60S13/c32-92(33,34)72-7-12-16(83-96(44,45)46)20(81-31-27(91-104(68,69)70)23(88-101(59,60)61)19(86-99(53,54)55)15(79-31)10-75-95(41,42)43)25(89-102(62,63)64)29(77-12)80-21-17(84-97(47,48)49)13(8-73-93(35,36)37)78-30(26(21)90-103(65,66)67)82-24-22(87-100(56,57)58)18(85-98(50,51)52)14(9-74-94(38,39)40)76-28(24)71-6-11-4-2-1-3-5-11/h1-5,12-31H,6-10H2,(H,32,33,34)(H,35,36,37)(H,38,39,40)(H,41,42,43)(H,44,45,46)(H,47,48,49)(H,50,51,52)(H,53,54,55)(H,56,57,58)(H,59,60,61)(H,62,63,64)(H,65,66,67)(H,68,69,70)/p-13/t12-,13-,14-,15-,16-,17-,18-,19-,20+,21+,22+,23+,24+,25+,26+,27+,28+,29-,30-,31-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a |
Progen Pharmaceuticals Limited
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon-based solution affinity assay |
J Med Chem 53: 1686-99 (2010)
Article DOI: 10.1021/jm901449m
BindingDB Entry DOI: 10.7270/Q2PG1SPH |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50307393
(3-(4-Phenyl[1,2,3]triazol-1-yl)propyl 2,3,4,6-Tetr...)Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](OCCCn2cc(nn2)-c2ccccc2)[C@@H](O[C@H]2O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@H]4O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]4OS([O-])(=O)=O)[C@@H]3OS([O-])(=O)=O)[C@@H]2OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C35H53N3O60S13/c39-99(40,41)79-10-16-20(90-103(51,52)53)24(88-35-31(98-111(75,76)77)27(95-108(66,67)68)23(93-106(60,61)62)19(86-35)13-82-102(48,49)50)29(96-109(69,70)71)33(84-16)87-25-21(91-104(54,55)56)17(11-80-100(42,43)44)85-34(30(25)97-110(72,73)74)89-28-26(94-107(63,64)65)22(92-105(57,58)59)18(12-81-101(45,46)47)83-32(28)78-8-4-7-38-9-15(36-37-38)14-5-2-1-3-6-14/h1-3,5-6,9,16-35H,4,7-8,10-13H2,(H,39,40,41)(H,42,43,44)(H,45,46,47)(H,48,49,50)(H,51,52,53)(H,54,55,56)(H,57,58,59)(H,60,61,62)(H,63,64,65)(H,66,67,68)(H,69,70,71)(H,72,73,74)(H,75,76,77)/p-13/t16-,17-,18-,19-,20-,21-,22-,23-,24+,25+,26+,27+,28+,29+,30+,31+,32+,33-,34-,35-/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a |
Progen Pharmaceuticals Limited
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon-based solution affinity assay |
J Med Chem 53: 1686-99 (2010)
Article DOI: 10.1021/jm901449m
BindingDB Entry DOI: 10.7270/Q2PG1SPH |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50428819
(GERANIN B)Show SMILES O[C@H]1Cc2c(O)cc3O[C@@]4(Oc5cc(O)cc(O)c5[C@@H]([C@H]4O)c3c2O[C@@H]1c1ccc(O)cc1)c1ccc(O)c(O)c1 |r,TLB:16:18:20:8.7.22,12:11:20:8.7.22| Show InChI InChI=1S/C30H24O11/c31-14-4-1-12(2-5-14)27-21(37)10-16-18(34)11-23-25(28(16)39-27)26-24-20(36)8-15(32)9-22(24)40-30(41-23,29(26)38)13-3-6-17(33)19(35)7-13/h1-9,11,21,26-27,29,31-38H,10H2/t21-,26+,27+,29+,30-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant VEGFA (unknown origin) measured for 60 seconds by surface plasmon resonance assay |
J Nat Prod 76: 29-35 (2013)
Article DOI: 10.1021/np300614u
BindingDB Entry DOI: 10.7270/Q24F1S3K |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50428821
(PROANTHOCYANIDIN A1)Show SMILES O[C@H]1Cc2c(O)cc3O[C@@]4(Oc5cc(O)cc(O)c5[C@@H]([C@H]4O)c3c2O[C@@H]1c1ccc(O)c(O)c1)c1ccc(O)c(O)c1 |r,THB:16:18:7.22.8:20,12:11:7.22.8:20| Show InChI InChI=1S/C30H24O12/c31-13-7-20(37)24-22(8-13)41-30(12-2-4-16(33)19(36)6-12)29(39)26(24)25-23(42-30)10-17(34)14-9-21(38)27(40-28(14)25)11-1-3-15(32)18(35)5-11/h1-8,10,21,26-27,29,31-39H,9H2/t21-,26+,27+,29+,30-/m0/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 476 | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Salerno
Curated by ChEMBL
| Assay Description
Binding affinity to recombinant VEGFA (unknown origin) measured for 60 seconds by surface plasmon resonance assay |
J Nat Prod 76: 29-35 (2013)
Article DOI: 10.1021/np300614u
BindingDB Entry DOI: 10.7270/Q24F1S3K |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50017345
(CHEMBL3288260)Show SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[H][C@]1(O[C@@H]2O[C@@H](C([O-])=O)[C@@]([H])(O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@]([H])(O[C@@H]4O[C@@H](C([O-])=O)[C@@]([H])(O[C@H]5O[C@H](COS([O-])(=O)=O)[C@@]([H])(O[C@@H]6O[C@H]([C@@H](O)[C@H](O)[C@H]6OS([O-])(=O)=O)C([O-])=O)[C@H](O)[C@H]5NC(C)=O)[C@H](O)[C@H]4OS([O-])(=O)=O)[C@H](O)[C@H]3NS([O-])(=O)=O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](NC(C)=O)[C@@H](OCCCCC)O[C@@H]1COS([O-])(=O)=O |r| Show InChI InChI=1S/C45H73N3O51S6.9Na/c1-4-5-6-7-83-40-16(46-11(2)49)19(51)27(13(87-40)8-84-101(68,69)70)90-43-25(57)24(56)30(35(96-43)38(61)62)93-42-18(48-100(65,66)67)21(53)29(15(89-42)10-86-103(74,75)76)92-45-34(99-105(80,81)82)26(58)31(36(97-45)39(63)64)94-41-17(47-12(3)50)20(52)28(14(88-41)9-85-102(71,72)73)91-44-33(98-104(77,78)79)23(55)22(54)32(95-44)37(59)60;;;;;;;;;/h13-36,40-45,48,51-58H,4-10H2,1-3H3,(H,46,49)(H,47,50)(H,59,60)(H,61,62)(H,63,64)(H,65,66,67)(H,68,69,70)(H,71,72,73)(H,74,75,76)(H,77,78,79)(H,80,81,82);;;;;;;;;/q;9*+1/p-9/t13-,14-,15-,16-,17-,18-,19-,20-,21-,22+,23+,24-,25-,26+,27-,28-,29-,30+,31+,32-,33-,34-,35-,36-,40+,41-,42-,43-,44-,45-;;;;;;;;;/m1........./s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a |
Momenta Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant VEGF165 by surface plasmon resonance assay |
J Med Chem 57: 4511-20 (2014)
Article DOI: 10.1021/jm4016069
BindingDB Entry DOI: 10.7270/Q2ZG6TSN |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421310
(CHEMBL2087906)Show SMILES CC(=O)N(CCc1ccccc1)CC(=O)NCCO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C20H30N2O20S4/c1-13(23)22(9-7-14-5-3-2-4-6-14)11-16(24)21-8-10-37-20-19(42-46(34,35)36)18(41-45(31,32)33)17(40-44(28,29)30)15(39-20)12-38-43(25,26)27/h2-6,15,17-20H,7-12H2,1H3,(H,21,24)(H,25,26,27)(H,28,29,30)(H,31,32,33)(H,34,35,36)/p-4/t15-,17-,18+,19+,20+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421311
(CHEMBL2087908)Show SMILES CCN(CC(=O)NCCO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)C(=O)CCC([O-])=O |r| Show InChI InChI=1S/C16H28N2O22S4/c1-2-18(11(20)3-4-12(21)22)7-10(19)17-5-6-35-16-15(40-44(32,33)34)14(39-43(29,30)31)13(38-42(26,27)28)9(37-16)8-36-41(23,24)25/h9,13-16H,2-8H2,1H3,(H,17,19)(H,21,22)(H,23,24,25)(H,26,27,28)(H,29,30,31)(H,32,33,34)/p-5/t9-,13-,14+,15+,16+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 4.00E+4 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421302
(CHEMBL2087895)Show SMILES CO[C@H]1O[C@H](CNC(=O)CNC(=O)Cc2cccc(Cl)c2)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C17H23ClN2O16S3/c1-32-17-16(36-39(29,30)31)15(35-38(26,27)28)14(34-37(23,24)25)11(33-17)7-19-13(22)8-20-12(21)6-9-3-2-4-10(18)5-9/h2-5,11,14-17H,6-8H2,1H3,(H,19,22)(H,20,21)(H,23,24,25)(H,26,27,28)(H,29,30,31)/p-3/t11-,14-,15+,16+,17+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 4.53E+4 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421312
(CHEMBL2087910)Show SMILES CCN(CC(=O)NCCO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)C(=O)CCCCCCCCCOS([O-])(=O)=O |r| Show InChI InChI=1S/C22H42N2O24S5/c1-2-24(18(26)10-8-6-4-3-5-7-9-12-43-49(27,28)29)14-17(25)23-11-13-42-22-21(48-53(39,40)41)20(47-52(36,37)38)19(46-51(33,34)35)16(45-22)15-44-50(30,31)32/h16,19-22H,2-15H2,1H3,(H,23,25)(H,27,28,29)(H,30,31,32)(H,33,34,35)(H,36,37,38)(H,39,40,41)/p-5/t16-,19-,20+,21+,22+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50017346
(CHEMBL3288258)Show SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[H][C@]1(O[C@@H]2O[C@@H](C([O-])=O)[C@@]([H])(O[C@H]3O[C@H](COS([O-])(=O)=O)[C@@]([H])(O[C@@H]4O[C@@H](C([O-])=O)[C@@]([H])(O[C@H]5O[C@H](COS([O-])(=O)=O)[C@@]([H])(O[C@@H]6O[C@H]([C@@H](O)[C@H](O)[C@H]6OS([O-])(=O)=O)C([O-])=O)[C@H](O)[C@H]5NC(C)=O)[C@H](O)[C@H]4OS([O-])(=O)=O)[C@H](O)[C@H]3NC(C)=O)[C@H](O)[C@H]2OS([O-])(=O)=O)[C@H](O)[C@@H](NC(C)=O)[C@@H](OCCCCC)O[C@@H]1COS([O-])(=O)=O |r| Show InChI InChI=1S/C47H75N3O52S6.9Na/c1-5-6-7-8-85-42-18(48-12(2)51)21(54)28(15(89-42)9-86-103(67,68)69)93-46-35(101-107(79,80)81)26(59)31(37(98-46)40(63)64)96-44-20(50-14(4)53)23(56)30(17(91-44)11-88-105(73,74)75)94-47-36(102-108(82,83)84)27(60)32(38(99-47)41(65)66)95-43-19(49-13(3)52)22(55)29(16(90-43)10-87-104(70,71)72)92-45-34(100-106(76,77)78)25(58)24(57)33(97-45)39(61)62;;;;;;;;;/h15-38,42-47,54-60H,5-11H2,1-4H3,(H,48,51)(H,49,52)(H,50,53)(H,61,62)(H,63,64)(H,65,66)(H,67,68,69)(H,70,71,72)(H,73,74,75)(H,76,77,78)(H,79,80,81)(H,82,83,84);;;;;;;;;/q;9*+1/p-9/t15-,16-,17-,18-,19-,20-,21-,22-,23-,24+,25+,26+,27+,28-,29-,30-,31+,32+,33-,34-,35-,36-,37-,38-,42+,43-,44-,45-,46-,47-;;;;;;;;;/m1........./s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 6.60E+4 | n/a | n/a | n/a | n/a | n/a |
Momenta Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant VEGF165 by surface plasmon resonance assay |
J Med Chem 57: 4511-20 (2014)
Article DOI: 10.1021/jm4016069
BindingDB Entry DOI: 10.7270/Q2ZG6TSN |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421296
(CHEMBL2087888)Show SMILES CO[C@H]1O[C@H](CNC(=O)CN(C(C)=O)c2ccccc2)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C17H24N2O16S3/c1-10(20)19(11-6-4-3-5-7-11)9-13(21)18-8-12-14(33-36(22,23)24)15(34-37(25,26)27)16(17(31-2)32-12)35-38(28,29)30/h3-7,12,14-17H,8-9H2,1-2H3,(H,18,21)(H,22,23,24)(H,25,26,27)(H,28,29,30)/p-3/t12-,14-,15+,16+,17+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.60E+4 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421309
(CHEMBL2087905)Show SMILES CC(=O)N(CC(=O)NCCO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)Cc1ccccc1 |r| Show InChI InChI=1S/C19H28N2O20S4/c1-12(22)21(9-13-5-3-2-4-6-13)10-15(23)20-7-8-36-19-18(41-45(33,34)35)17(40-44(30,31)32)16(39-43(27,28)29)14(38-19)11-37-42(24,25)26/h2-6,14,16-19H,7-11H2,1H3,(H,20,23)(H,24,25,26)(H,27,28,29)(H,30,31,32)(H,33,34,35)/p-4/t14-,16-,17+,18+,19+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.66E+4 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421298
(CHEMBL2087889)Show SMILES CO[C@H]1O[C@H](CNC(=O)CN(Cc2ccccc2)C(C)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C18H26N2O16S3/c1-11(21)20(9-12-6-4-3-5-7-12)10-14(22)19-8-13-15(34-37(23,24)25)16(35-38(26,27)28)17(18(32-2)33-13)36-39(29,30)31/h3-7,13,15-18H,8-10H2,1-2H3,(H,19,22)(H,23,24,25)(H,26,27,28)(H,29,30,31)/p-3/t13-,15-,16+,17+,18+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 7.70E+4 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421318
(CHEMBL2087909)Show SMILES CCN(CC(=O)NCCO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)C(=O)CCCCC([O-])=O |r| Show InChI InChI=1S/C18H32N2O22S4/c1-2-20(13(22)5-3-4-6-14(23)24)9-12(21)19-7-8-37-18-17(42-46(34,35)36)16(41-45(31,32)33)15(40-44(28,29)30)11(39-18)10-38-43(25,26)27/h11,15-18H,2-10H2,1H3,(H,19,21)(H,23,24)(H,25,26,27)(H,28,29,30)(H,31,32,33)(H,34,35,36)/p-5/t11-,15-,16+,17+,18+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 8.10E+4 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421308
(CHEMBL2087903)Show SMILES CCN(CC(=O)NC[C@H]1O[C@H](OC)[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)C(=O)CCCc1ccccc1 |r| Show InChI InChI=1S/C21H32N2O16S3/c1-3-23(17(25)11-7-10-14-8-5-4-6-9-14)13-16(24)22-12-15-18(37-40(26,27)28)19(38-41(29,30)31)20(21(35-2)36-15)39-42(32,33)34/h4-6,8-9,15,18-21H,3,7,10-13H2,1-2H3,(H,22,24)(H,26,27,28)(H,29,30,31)(H,32,33,34)/p-3/t15-,18-,19+,20+,21+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 8.10E+4 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50017347
(CHEMBL3288259)Show SMILES [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[Na+].[H][C@]1(O[C@@H]2O[C@H]([C@@H](O)[C@H](O)[C@H]2OS([O-])(=O)=O)C([O-])=O)[C@H](O)[C@@H](NS([O-])(=O)=O)[C@@H](O[C@@]2([H])[C@H](O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@@]3([H])[C@H](O)[C@@H](NS([O-])(=O)=O)[C@@H](O[C@@]4([H])[C@H](O)[C@@H](OS([O-])(=O)=O)[C@H](O[C@@]5([H])[C@H](O)[C@@H](NS([O-])(=O)=O)[C@@H](OCCCCCN)O[C@@H]5CO)O[C@H]4C([O-])=O)O[C@@H]3CO)O[C@H]2C([O-])=O)O[C@@H]1CO |r| Show InChI InChI=1S/C41H70N4O49S6.9Na/c42-4-2-1-3-5-80-36-12(43-95(62,63)64)15(49)22(9(6-46)81-36)85-40-29(93-99(74,75)76)20(54)25(31(90-40)34(58)59)88-38-14(45-97(68,69)70)17(51)24(11(8-48)83-38)86-41-30(94-100(77,78)79)21(55)26(32(91-41)35(60)61)87-37-13(44-96(65,66)67)16(50)23(10(7-47)82-37)84-39-28(92-98(71,72)73)19(53)18(52)27(89-39)33(56)57;;;;;;;;;/h9-32,36-41,43-55H,1-8,42H2,(H,56,57)(H,58,59)(H,60,61)(H,62,63,64)(H,65,66,67)(H,68,69,70)(H,71,72,73)(H,74,75,76)(H,77,78,79);;;;;;;;;/q;9*+1/p-9/t9-,10-,11-,12-,13-,14-,15-,16-,17-,18+,19+,20+,21+,22-,23-,24-,25+,26+,27-,28-,29-,30-,31-,32-,36+,37-,38-,39-,40-,41-;;;;;;;;;/m1........./s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 8.60E+4 | n/a | n/a | n/a | n/a | n/a |
Momenta Pharmaceuticals Inc.
Curated by ChEMBL
| Assay Description
Binding affinity to human recombinant VEGF165 by surface plasmon resonance assay |
J Med Chem 57: 4511-20 (2014)
Article DOI: 10.1021/jm4016069
BindingDB Entry DOI: 10.7270/Q2ZG6TSN |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421295
(CHEMBL2087907)Show SMILES [O-]S(=O)(=O)OC[C@H]1O[C@H](OCCNC(=O)CNC(=O)Cc2cccc(Cl)c2)[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C18H25ClN2O20S4/c19-11-3-1-2-10(6-11)7-13(22)21-8-14(23)20-4-5-36-18-17(41-45(33,34)35)16(40-44(30,31)32)15(39-43(27,28)29)12(38-18)9-37-42(24,25)26/h1-3,6,12,15-18H,4-5,7-9H2,(H,20,23)(H,21,22)(H,24,25,26)(H,27,28,29)(H,30,31,32)(H,33,34,35)/p-4/t12-,15-,16+,17+,18+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 9.10E+4 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421305
(CHEMBL2087899)Show SMILES CCN(CC(=O)NC[C@H]1O[C@H](OC)[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)C(=O)CCCCC([O-])=O |r| Show InChI InChI=1S/C17H30N2O18S3/c1-3-19(12(21)6-4-5-7-13(22)23)9-11(20)18-8-10-14(35-38(24,25)26)15(36-39(27,28)29)16(17(33-2)34-10)37-40(30,31)32/h10,14-17H,3-9H2,1-2H3,(H,18,20)(H,22,23)(H,24,25,26)(H,27,28,29)(H,30,31,32)/p-4/t10-,14-,15+,16+,17+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.04E+5 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421299
(CHEMBL2087890)Show SMILES CO[C@H]1O[C@H](CNC(=O)CN(CCc2ccccc2)C(C)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C19H28N2O16S3/c1-12(22)21(9-8-13-6-4-3-5-7-13)11-15(23)20-10-14-16(35-38(24,25)26)17(36-39(27,28)29)18(19(33-2)34-14)37-40(30,31)32/h3-7,14,16-19H,8-11H2,1-2H3,(H,20,23)(H,24,25,26)(H,27,28,29)(H,30,31,32)/p-3/t14-,16-,17+,18+,19+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.09E+5 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421314
(CHEMBL2087912)Show SMILES CO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C7H14O18S4/c1-20-7-6(25-29(17,18)19)5(24-28(14,15)16)4(23-27(11,12)13)3(22-7)2-21-26(8,9)10/h3-7H,2H2,1H3,(H,8,9,10)(H,11,12,13)(H,14,15,16)(H,17,18,19)/p-4/t3-,4-,5+,6+,7+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.98E+5 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421316
(CHEMBL2087898)Show SMILES CCN(CC(=O)NC[C@H]1O[C@H](OC)[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)C(=O)CCC([O-])=O |r| Show InChI InChI=1S/C15H26N2O18S3/c1-3-17(10(19)4-5-11(20)21)7-9(18)16-6-8-12(33-36(22,23)24)13(34-37(25,26)27)14(15(31-2)32-8)35-38(28,29)30/h8,12-15H,3-7H2,1-2H3,(H,16,18)(H,20,21)(H,22,23,24)(H,25,26,27)(H,28,29,30)/p-4/t8-,12-,13+,14+,15+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.07E+5 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421303
(CHEMBL2087896)Show SMILES CO[C@H]1O[C@H](CNC(=O)CN(CCOS([O-])(=O)=O)C(C)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C13H24N2O20S4/c1-7(16)15(3-4-31-36(18,19)20)6-9(17)14-5-8-10(33-37(21,22)23)11(34-38(24,25)26)12(13(30-2)32-8)35-39(27,28)29/h8,10-13H,3-6H2,1-2H3,(H,14,17)(H,18,19,20)(H,21,22,23)(H,24,25,26)(H,27,28,29)/p-4/t8-,10-,11+,12+,13+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 2.80E+5 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421317
(CHEMBL2087904)Show SMILES CC(=O)N(CC(=O)NCCO[C@H]1O[C@H](COS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)c1ccccc1 |r| Show InChI InChI=1S/C18H26N2O20S4/c1-11(21)20(12-5-3-2-4-6-12)9-14(22)19-7-8-35-18-17(40-44(32,33)34)16(39-43(29,30)31)15(38-42(26,27)28)13(37-18)10-36-41(23,24)25/h2-6,13,15-18H,7-10H2,1H3,(H,19,22)(H,23,24,25)(H,26,27,28)(H,29,30,31)(H,32,33,34)/p-4/t13-,15-,16+,17+,18+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 4.02E+5 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421304
(CHEMBL2087897)Show SMILES CCN(CC(=O)NC[C@H]1O[C@H](OC)[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)C(=O)COS([O-])(=O)=O |r| Show InChI InChI=1S/C13H24N2O20S4/c1-3-15(9(17)6-31-36(18,19)20)5-8(16)14-4-7-10(33-37(21,22)23)11(34-38(24,25)26)12(13(30-2)32-7)35-39(27,28)29/h7,10-13H,3-6H2,1-2H3,(H,14,16)(H,18,19,20)(H,21,22,23)(H,24,25,26)(H,27,28,29)/p-4/t7-,10-,11+,12+,13+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.12E+5 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421306
(CHEMBL2087900)Show SMILES CCN(CC(=O)NC[C@H]1O[C@H](OC)[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)C(=O)CCCCCCCCCOS([O-])(=O)=O |r| Show InChI InChI=1S/C21H40N2O20S4/c1-3-23(17(25)11-9-7-5-4-6-8-10-12-39-44(26,27)28)14-16(24)22-13-15-18(41-45(29,30)31)19(42-46(32,33)34)20(21(38-2)40-15)43-47(35,36)37/h15,18-21H,3-14H2,1-2H3,(H,22,24)(H,26,27,28)(H,29,30,31)(H,32,33,34)(H,35,36,37)/p-4/t15-,18-,19+,20+,21+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.45E+5 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421319
(CHEMBL2087902)Show SMILES CCN(CC(=O)NC[C@H]1O[C@H](OC)[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)C(=O)CCc1ccccc1 |r| Show InChI InChI=1S/C20H30N2O16S3/c1-3-22(16(24)10-9-13-7-5-4-6-8-13)12-15(23)21-11-14-17(36-39(25,26)27)18(37-40(28,29)30)19(20(34-2)35-14)38-41(31,32)33/h4-8,14,17-20H,3,9-12H2,1-2H3,(H,21,23)(H,25,26,27)(H,28,29,30)(H,31,32,33)/p-3/t14-,17-,18+,19+,20+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 5.96E+5 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421313
(CHEMBL2087911)Show SMILES CO[C@H]1O[C@H](CN=[N+]=[N-])[C@@H](OS([O-])(=O)=O)[C@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O |r| Show InChI InChI=1S/C7H13N3O14S3/c1-20-7-6(24-27(17,18)19)5(23-26(14,15)16)4(22-25(11,12)13)3(21-7)2-9-10-8/h3-7H,2H2,1H3,(H,11,12,13)(H,14,15,16)(H,17,18,19)/p-3/t3-,4-,5+,6+,7+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 6.30E+5 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421301
(CHEMBL2087894)Show SMILES CCCCC1CCC(CC1)N(CC(=O)NC[C@H]1O[C@H](OC)[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)C(C)=O |r,wU:16.16,27.28,21.22,wD:33.35,18.19,(14.12,3.67,;12.79,2.9,;12.78,1.36,;11.45,.59,;11.45,-.95,;10.12,-1.73,;10.12,-3.27,;11.45,-4.03,;12.78,-3.27,;12.77,-1.73,;11.45,-5.57,;10.12,-6.33,;8.78,-5.56,;8.79,-4.02,;7.45,-6.32,;6.12,-5.55,;4.78,-6.32,;4.78,-7.86,;3.45,-8.62,;3.45,-10.16,;4.79,-10.93,;2.12,-7.86,;.79,-8.63,;.79,-10.17,;-.54,-10.94,;2.33,-10.17,;1.55,-11.5,;2.12,-6.32,;.79,-5.55,;-.54,-6.32,;-1.88,-5.56,;-1.32,-7.65,;.22,-7.65,;3.45,-5.54,;3.45,-4,;2.12,-3.23,;.78,-4,;1.34,-1.89,;2.88,-1.89,;12.78,-6.34,;12.78,-7.88,;14.12,-5.57,)| Show InChI InChI=1S/C21H38N2O16S3/c1-4-5-6-14-7-9-15(10-8-14)23(13(2)24)12-17(25)22-11-16-18(37-40(26,27)28)19(38-41(29,30)31)20(21(35-3)36-16)39-42(32,33)34/h14-16,18-21H,4-12H2,1-3H3,(H,22,25)(H,26,27,28)(H,29,30,31)(H,32,33,34)/p-3/t14?,15?,16-,18-,19+,20+,21+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.00E+6 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
Vascular endothelial growth factor A
(Homo sapiens (Human)) | BDBM50421307
(CHEMBL2087901)Show SMILES CCN(CC(=O)NC[C@H]1O[C@H](OC)[C@@H](OS([O-])(=O)=O)[C@@H](OS([O-])(=O)=O)[C@@H]1OS([O-])(=O)=O)C(=O)c1ccccc1 |r| Show InChI InChI=1S/C18H26N2O16S3/c1-3-20(17(22)11-7-5-4-6-8-11)10-13(21)19-9-12-14(34-37(23,24)25)15(35-38(26,27)28)16(18(32-2)33-12)36-39(29,30)31/h4-8,12,14-16,18H,3,9-10H2,1-2H3,(H,19,21)(H,23,24,25)(H,26,27,28)(H,29,30,31)/p-3/t12-,14-,15+,16+,18+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
KEGG
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 1.10E+6 | n/a | n/a | n/a | n/a | n/a |
The University of Queensland
Curated by ChEMBL
| Assay Description
Binding affinity to VEGF by surface plasmon resonance-based solution affinity assay |
Bioorg Med Chem Lett 22: 6190-4 (2012)
Article DOI: 10.1016/j.bmcl.2012.08.001
BindingDB Entry DOI: 10.7270/Q2QR4ZD6 |
More data for this
Ligand-Target Pair | |
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