Compile Data Set for Download or QSAR

Found 214 hits of ki data for polymerid = 575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50237710 (4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...) Show SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc(c1)C(F)(F)F Show InChI InChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 103: 3153-8 (2006) Article DOI: 10.1073/pnas.0511292103 BindingDB Entry DOI: 10.7270/Q21Z430B
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM13530 (4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1 Show InChI InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genomics Institute of the Novartis Research Foundation Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 103: 3153-8 (2006) Article DOI: 10.1073/pnas.0511292103 BindingDB Entry DOI: 10.7270/Q21Z430B
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507078 (US11046672, Example 27) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NOCCCN(C)C)c3ccccc3)c2cc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445247 (US10669235, Example 38 | US11208381, Example 38) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCC(CO)(CN(C)C)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C34H38N4O5/c1-22-18-27-28(19-26(22)33(42)43-4)36-31(40)29(27)30(23-8-6-5-7-9-23)35-25-12-10-24(11-13-25)32(41)38-16-14-34(21-39,15-17-38)20-37(2)3/h5-13,18-19,35,39H,14-17,20-21H2,1-4H3,(H,36,40)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445247 (US10669235, Example 38 | US11208381, Example 38) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCC(CO)(CN(C)C)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C34H38N4O5/c1-22-18-27-28(19-26(22)33(42)43-4)36-31(40)29(27)30(23-8-6-5-7-9-23)35-25-12-10-24(11-13-25)32(41)38-16-14-34(21-39,15-17-38)20-37(2)3/h5-13,18-19,35,39H,14-17,20-21H2,1-4H3,(H,36,40)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445240 (US10669235, Example 31 | US11208381, Example 31) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCC(CC3)C(=O)NCCN(C)C)c3ccccc3)c2cc1C Show InChI InChI=1S/C35H39N5O5/c1-22-20-28-29(21-27(22)35(44)45-4)38-33(42)30(28)31(23-8-6-5-7-9-23)37-26-12-10-25(11-13-26)34(43)40-17-14-24(15-18-40)32(41)36-16-19-39(2)3/h5-13,20-21,24,37H,14-19H2,1-4H3,(H,36,41)(H,38,42)/b31-30-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445240 (US10669235, Example 31 | US11208381, Example 31) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCC(CC3)C(=O)NCCN(C)C)c3ccccc3)c2cc1C Show InChI InChI=1S/C35H39N5O5/c1-22-20-28-29(21-27(22)35(44)45-4)38-33(42)30(28)31(23-8-6-5-7-9-23)37-26-12-10-25(11-13-26)34(43)40-17-14-24(15-18-40)32(41)36-16-19-39(2)3/h5-13,20-21,24,37H,14-19H2,1-4H3,(H,36,41)(H,38,42)/b31-30-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507083 (US11046672, Example 32) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(C(=O)NOCCN4CCN(C)CC4)c(F)c3)c3ccccc3)c2cc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4.92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM531233 ((Z)-Methyl 3-(((4-(4-(2-((2-hydroxyethyl)amino)-2-...) Show SMILES COC(=O)c1cc2N(C(C)=O)C(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCN(CC(=O)OC(C)(C)C)CC3)c3ccccc3)c2cc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445224 (US10669235, Example 15) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCN(CC(=O)NCCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H35N5O6/c1-21-18-26-27(19-25(21)33(43)44-2)36-31(41)29(26)30(22-6-4-3-5-7-22)35-24-10-8-23(9-11-24)32(42)38-15-13-37(14-16-38)20-28(40)34-12-17-39/h3-11,18-19,35,39H,12-17,20H2,1-2H3,(H,34,40)(H,36,41)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445241 (US10669235, Example 32 | US11208381, Example 32) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N(CCO)CCN(C)C)c3ccccc3)c2cc1C Show InChI InChI=1S/C31H34N4O5/c1-20-18-25-26(19-24(20)31(39)40-4)33-29(37)27(25)28(21-8-6-5-7-9-21)32-23-12-10-22(11-13-23)30(38)35(16-17-36)15-14-34(2)3/h5-13,18-19,32,36H,14-17H2,1-4H3,(H,33,37)/b28-27-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.02	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445241 (US10669235, Example 32 | US11208381, Example 32) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N(CCO)CCN(C)C)c3ccccc3)c2cc1C Show InChI InChI=1S/C31H34N4O5/c1-20-18-25-26(19-24(20)31(39)40-4)33-29(37)27(25)28(21-8-6-5-7-9-21)32-23-12-10-22(11-13-23)30(38)35(16-17-36)15-14-34(2)3/h5-13,18-19,32,36H,14-17H2,1-4H3,(H,33,37)/b28-27-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.02	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507090 (US11046672, Example 39) Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)C(=O)NOCCN3CCN(CCO)CC3)c3ccccc3)C(=O)Nc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445216 (US10669235, Example 7 | US11208381, Example 7) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCC(=O)N3CCN(CCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H35N5O6/c1-21-18-26-27(19-25(21)33(43)44-2)36-32(42)29(26)30(22-6-4-3-5-7-22)35-24-10-8-23(9-11-24)31(41)34-20-28(40)38-14-12-37(13-15-38)16-17-39/h3-11,18-19,35,39H,12-17,20H2,1-2H3,(H,34,41)(H,36,42)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445216 (US10669235, Example 7 | US11208381, Example 7) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCC(=O)N3CCN(CCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H35N5O6/c1-21-18-26-27(19-25(21)33(43)44-2)36-32(42)29(26)30(22-6-4-3-5-7-22)35-24-10-8-23(9-11-24)31(41)34-20-28(40)38-14-12-37(13-15-38)16-17-39/h3-11,18-19,35,39H,12-17,20H2,1-2H3,(H,34,41)(H,36,42)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	5.76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445230 (US10669235, Example 21 | US11208381, Example 21) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCCCN3CCN(C)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H37N5O4/c1-22-20-27-28(21-26(22)33(41)42-3)36-32(40)29(27)30(23-8-5-4-6-9-23)35-25-12-10-24(11-13-25)31(39)34-14-7-15-38-18-16-37(2)17-19-38/h4-6,8-13,20-21,35H,7,14-19H2,1-3H3,(H,34,39)(H,36,40)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445230 (US10669235, Example 21 | US11208381, Example 21) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCCCN3CCN(C)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C33H37N5O4/c1-22-20-27-28(21-26(22)33(41)42-3)36-32(40)29(27)30(23-8-5-4-6-9-23)35-25-12-10-24(11-13-25)31(39)34-14-7-15-38-18-16-37(2)17-19-38/h4-6,8-13,20-21,35H,7,14-19H2,1-3H3,(H,34,39)(H,36,40)/b30-29-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507082 (US11046672, Example 31) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(C(=O)NOC4CCN(C)CC4)c(C)c3)c3ccccc3)c2cc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507058 ((Z)-Methyl 3-(((4-((2-(4-(2-hydroxyethyl)piperazin...) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NOCCN3CCN(CCO)CC3)c3ccccc3)c2cc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445255 (US10669235, Example 46 | US11208381, Example 46) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCCN(CCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C32H34N4O5/c1-21-19-26-27(20-25(21)32(40)41-2)34-30(38)28(26)29(22-7-4-3-5-8-22)33-24-11-9-23(10-12-24)31(39)36-14-6-13-35(15-16-36)17-18-37/h3-5,7-12,19-20,33,37H,6,13-18H2,1-2H3,(H,34,38)/b29-28-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445255 (US10669235, Example 46 | US11208381, Example 46) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCCN(CCO)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C32H34N4O5/c1-21-19-26-27(20-25(21)32(40)41-2)34-30(38)28(26)29(22-7-4-3-5-8-22)33-24-11-9-23(10-12-24)31(39)36-14-6-13-35(15-16-36)17-18-37/h3-5,7-12,19-20,33,37H,6,13-18H2,1-2H3,(H,34,38)/b29-28-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445242 (US10669235, Example 33 | US11208381, Example 33) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CC[C@@H](CN(C)C)[C@H](O)C3)c3ccccc3)c2cc1C |r| Show InChI InChI=1S/C33H36N4O5/c1-20-16-26-27(17-25(20)33(41)42-4)35-31(39)29(26)30(21-8-6-5-7-9-21)34-24-12-10-22(11-13-24)32(40)37-15-14-23(18-36(2)3)28(38)19-37/h5-13,16-17,23,28,34,38H,14-15,18-19H2,1-4H3,(H,35,39)/b30-29-/t23-,28+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445242 (US10669235, Example 33 | US11208381, Example 33) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CC[C@@H](CN(C)C)[C@H](O)C3)c3ccccc3)c2cc1C |r| Show InChI InChI=1S/C33H36N4O5/c1-20-16-26-27(17-25(20)33(41)42-4)35-31(39)29(26)30(21-8-6-5-7-9-21)34-24-12-10-22(11-13-24)32(40)37-15-14-23(18-36(2)3)28(38)19-37/h5-13,16-17,23,28,34,38H,14-15,18-19H2,1-4H3,(H,35,39)/b30-29-/t23-,28+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445212 (US10669235, Example 3 | US11208381, Example 3) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCC3CCN(C)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C32H34N4O4/c1-20-17-26-27(18-25(20)32(39)40-3)35-31(38)28(26)29(22-7-5-4-6-8-22)34-24-11-9-23(10-12-24)30(37)33-19-21-13-15-36(2)16-14-21/h4-12,17-18,21,34H,13-16,19H2,1-3H3,(H,33,37)(H,35,38)/b29-28-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445212 (US10669235, Example 3 | US11208381, Example 3) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCC3CCN(C)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C32H34N4O4/c1-20-17-26-27(18-25(20)32(39)40-3)35-31(38)28(26)29(22-7-5-4-6-8-22)34-24-11-9-23(10-12-24)30(37)33-19-21-13-15-36(2)16-14-21/h4-12,17-18,21,34H,13-16,19H2,1-3H3,(H,33,37)(H,35,38)/b29-28-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507089 (US11046672, Example 38) Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)C(=O)NOCCN3CC[C@@H](C3)N(C)C)c3ccccc3)C(=O)Nc2c1 |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	6.91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507093 (US11046672, Example 42) Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)C(=O)NOCCN3CCNC(=O)C3)c3ccccc3)C(=O)Nc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.06	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507056 ((Z)-Methyl 3-(((4-((2-(dimethylamino)ethoxy)carbam...) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(C(=O)NOCCN(C)C)c(C)c3)c3ccccc3)c2cc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507107 (US11046672, Example 56) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N(C)OCCN(C)CCO)c3ccccc3)c2cc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507081 (US11046672, Example 30) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NOC3CCN(C)CC3)c3ccccc3)c2cc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507080 (US11046672, Example 29) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(C(=O)NOCCCN(C)C)c(C)c3)c3ccccc3)c2cc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445246 (US10669235, Example 37 | US11208381, Example 37) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCC(O)(CN4CCCC4)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C35H38N4O5/c1-23-20-28-29(21-27(23)34(42)44-2)37-32(40)30(28)31(24-8-4-3-5-9-24)36-26-12-10-25(11-13-26)33(41)39-18-14-35(43,15-19-39)22-38-16-6-7-17-38/h3-5,8-13,20-21,36,43H,6-7,14-19,22H2,1-2H3,(H,37,40)/b31-30-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445246 (US10669235, Example 37 | US11208381, Example 37) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)N3CCC(O)(CN4CCCC4)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C35H38N4O5/c1-23-20-28-29(21-27(23)34(42)44-2)37-32(40)30(28)31(24-8-4-3-5-9-24)36-26-12-10-25(11-13-26)33(41)39-18-14-35(43,15-19-39)22-38-16-6-7-17-38/h3-5,8-13,20-21,36,43H,6-7,14-19,22H2,1-2H3,(H,37,40)/b31-30-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507091 (US11046672, Example 40) Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)C(=O)NOCCN3CCC(O)CC3)c3ccccc3)C(=O)Nc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507079 (US11046672, Example 28) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(C(=O)NOCCN4CCN(C)CC4)c(C)c3)c3ccccc3)c2cc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.88	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445218 (US10669235, Example 9 | US11208381, Example 9) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCCN3CCNC(=O)C3)c3ccccc3)c2cc1C Show InChI InChI=1S/C31H31N5O5/c1-19-16-24-25(17-23(19)31(40)41-2)35-30(39)27(24)28(20-6-4-3-5-7-20)34-22-10-8-21(9-11-22)29(38)33-13-15-36-14-12-32-26(37)18-36/h3-11,16-17,34H,12-15,18H2,1-2H3,(H,32,37)(H,33,38)(H,35,39)/b28-27-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445218 (US10669235, Example 9 | US11208381, Example 9) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCCN3CCNC(=O)C3)c3ccccc3)c2cc1C Show InChI InChI=1S/C31H31N5O5/c1-19-16-24-25(17-23(19)31(40)41-2)35-30(39)27(24)28(20-6-4-3-5-7-20)34-22-10-8-21(9-11-22)29(38)33-13-15-36-14-12-32-26(37)18-36/h3-11,16-17,34H,12-15,18H2,1-2H3,(H,32,37)(H,33,38)(H,35,39)/b28-27-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507122 (US11046672, Example 73) Show SMILES CNC(=O)CN1CCN(CCONC(=O)c2ccc(N\C(=C3/C(=O)Nc4cc(C(=O)OC)c(C)cc34)c3ccccc3)cc2)CC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445227 (US10669235, Example 18 | US11208381, Example 18) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NC3CCN(C)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C31H32N4O4/c1-19-17-25-26(18-24(19)31(38)39-3)34-30(37)27(25)28(20-7-5-4-6-8-20)32-22-11-9-21(10-12-22)29(36)33-23-13-15-35(2)16-14-23/h4-12,17-18,23,32H,13-16H2,1-3H3,(H,33,36)(H,34,37)/b28-27-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445227 (US10669235, Example 18 | US11208381, Example 18) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NC3CCN(C)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C31H32N4O4/c1-19-17-25-26(18-24(19)31(38)39-3)34-30(37)27(25)28(20-7-5-4-6-8-20)32-22-11-9-21(10-12-22)29(36)33-23-13-15-35(2)16-14-23/h4-12,17-18,23,32H,13-16H2,1-3H3,(H,33,36)(H,34,37)/b28-27-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	7.99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM4814 (CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...) Show SMILES CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C Show InChI InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Qilu Pharmaceutical Co, Ltd Curated by ChEMBL					Assay Description Binding affinity to PDGFR-beta (unknown origin)				Eur J Med Chem 82: 139-51 (2014) Article DOI: 10.1016/j.ejmech.2014.05.051 BindingDB Entry DOI: 10.7270/Q2F1918D
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445209 (US10669235, Nintedanib) Show SMILES COC(=O)c1ccc2c(C(=Nc3ccc(cc3)N(C)C(=O)CN3CCN(C)CC3)c3ccccc3)c(O)[nH]c2c1 |w:10.10| Show InChI InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14,19,33,38H,15-18,20H2,1-3H3/b32-29+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50026612 (BIBF-1120 | Nintedanib | US10981896, Compound Nint...) Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)N(C)C(=O)CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1 Show InChI InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14,19,32H,15-18,20H2,1-3H3,(H,33,38)/b29-28-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50026612 (BIBF-1120 | Nintedanib | US10981896, Compound Nint...) Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)N(C)C(=O)CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1 Show InChI InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14,19,32H,15-18,20H2,1-3H3,(H,33,38)/b29-28-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445217 (US10669235, Example 8 | US11208381, Example 8) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCC(=O)N3CCN(C)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C32H33N5O5/c1-20-17-25-26(18-24(20)32(41)42-3)35-31(40)28(25)29(21-7-5-4-6-8-21)34-23-11-9-22(10-12-23)30(39)33-19-27(38)37-15-13-36(2)14-16-37/h4-12,17-18,34H,13-16,19H2,1-3H3,(H,33,39)(H,35,40)/b29-28-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...				Citation and Details BindingDB Entry DOI: 10.7270/Q2XP784N
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM445217 (US10669235, Example 8 | US11208381, Example 8) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NCC(=O)N3CCN(C)CC3)c3ccccc3)c2cc1C Show InChI InChI=1S/C32H33N5O5/c1-20-17-25-26(18-24(20)32(41)42-3)35-31(40)28(25)29(21-7-5-4-6-8-21)34-23-11-9-22(10-12-23)30(39)33-19-27(38)37-15-13-36(2)14-16-37/h4-12,17-18,34H,13-16,19H2,1-3H3,(H,33,39)(H,35,40)/b29-28-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
RESPIVERT LIMITED US Patent					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				US Patent US10669235 (2020) BindingDB Entry DOI: 10.7270/Q2XW4NVJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507057 ((Z)-Methyl 5-methyl-3-(((4-((2-(4-methylpiperazin-...) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NOCCN3CCN(C)CC3)c3ccccc3)c2cc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507087 (US11046672, Example 36) Show SMILES CCN1CCN(CCONC(=O)c2ccc(N\C(=C3/C(=O)Nc4cc(C(=O)OC)c(C)cc34)c3ccccc3)cc2)CC1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507084 (US11046672, Example 33) Show SMILES COC(=O)c1ccc2\C(=C(\Nc3ccc(C(=O)NOCCN4CCN(C)CC4)c(F)c3)c3ccccc3)C(=O)Nc2c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM507077 (US11046672, Example 26) Show SMILES COC(=O)c1cc2NC(=O)\C(=C(/Nc3ccc(cc3)C(=O)NOCCN(C)C)c3ccccc3)c2cc1C Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8.61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The inhibitory activities of compounds of the invention against PDGFRβ (PDGFRβ Kinase Enzyme System: Promega), were evaluated by mixing the...				Citation and Details BindingDB Entry DOI: 10.7270/Q27084K3
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 214 total )  |  Next  |  Last  >>

Jump to: