Compile Data Set for Download or QSAR

Found 2186 hits of ki for UniProtKB: Q923Y8   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM109401 (US8604061, 115) Show SMILES Cc1cccc(CC[C@H]2COC(N)=N2)c1 |r,c:12| Show InChI InChI=1S/C12H16N2O/c1-9-3-2-4-10(7-9)5-6-11-8-15-12(13)14-11/h2-4,7,11H,5-6,8H2,1H3,(H2,13,14)/t11-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM119143 (US8673950, 10) Show SMILES Cc1cc(Nc2ccc(CC[C@H]3COC(N)=N3)cc2)ccc1OC(F)(F)F |r,c:15| Show InChI InChI=1S/C19H20F3N3O2/c1-12-10-15(8-9-17(12)27-19(20,21)22)24-14-5-2-13(3-6-14)4-7-16-11-26-18(23)25-16/h2-3,5-6,8-10,16,24H,4,7,11H2,1H3,(H2,23,25)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-LaRoche Inc. US Patent					Assay Description The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration...				US Patent US8673950 (2014) BindingDB Entry DOI: 10.7270/Q29S1PQD
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122323 (US8729113, 35) Show SMILES NC1=N[C@@H](CCOc2cccc(Br)c2)CO1 |r,t:1| Show InChI InChI=1S/C11H13BrN2O2/c12-8-2-1-3-10(6-8)15-5-4-9-7-16-11(13)14-9/h1-3,6,9H,4-5,7H2,(H2,13,14)/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.100	-12.7	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122301 (US8729113, 8) Show SMILES NC1=N[C@@H](CCOc2ccc(F)c(Cl)c2)CO1 |r,t:1| Show InChI InChI=1S/C11H12ClFN2O2/c12-9-5-8(1-2-10(9)13)16-4-3-7-6-17-11(14)15-7/h1-2,5,7H,3-4,6H2,(H2,14,15)/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	-12.3	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240675 (US9416127, 12) Show SMILES Clc1cccc(c1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18ClN5O2/c20-14-2-1-3-16(10-14)25-22-11-17(24-25)19(26)23-15-6-4-13(5-7-15)18-12-21-8-9-27-18/h1-7,10-11,18,21H,8-9,12H2,(H,23,26)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	-13.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM119191 (US8673950, 58) Show SMILES CCC(CC)c1cnc(Nc2ccc(CC[C@H]3COC(N)=N3)cc2)nc1 |r,c:20| Show InChI InChI=1S/C20H27N5O/c1-3-15(4-2)16-11-22-20(23-12-16)25-17-8-5-14(6-9-17)7-10-18-13-26-19(21)24-18/h5-6,8-9,11-12,15,18H,3-4,7,10,13H2,1-2H3,(H2,21,24)(H,22,23,25)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-LaRoche Inc. US Patent					Assay Description The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration...				US Patent US8673950 (2014) BindingDB Entry DOI: 10.7270/Q29S1PQD
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM119144 (US8673950, 11) Show SMILES NC1=N[C@@H](CCc2ccc(Nc3ccc(cn3)C(F)(F)F)cc2)CO1 |r,t:1| Show InChI InChI=1S/C17H17F3N4O/c18-17(19,20)12-4-8-15(22-9-12)23-13-5-1-11(2-6-13)3-7-14-10-25-16(21)24-14/h1-2,4-6,8-9,14H,3,7,10H2,(H2,21,24)(H,22,23)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-LaRoche Inc. US Patent					Assay Description The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration...				US Patent US8673950 (2014) BindingDB Entry DOI: 10.7270/Q29S1PQD
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM119152 (US8673950, 19) Show SMILES NC1=N[C@@H](CCc2ccc(Nc3ccc(Cl)c(Cl)c3)cc2)CO1 |r,t:1| Show InChI InChI=1S/C17H17Cl2N3O/c18-15-8-7-13(9-16(15)19)21-12-4-1-11(2-5-12)3-6-14-10-23-17(20)22-14/h1-2,4-5,7-9,14,21H,3,6,10H2,(H2,20,22)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-LaRoche Inc. US Patent					Assay Description The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration...				US Patent US8673950 (2014) BindingDB Entry DOI: 10.7270/Q29S1PQD
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM119139 (US8673950, 6) Show SMILES NC1=N[C@@H](CCc2ccc(Nc3ccc(Cl)cc3)cc2)CO1 |r,t:1| Show InChI InChI=1S/C17H18ClN3O/c18-13-4-9-15(10-5-13)20-14-6-1-12(2-7-14)3-8-16-11-22-17(19)21-16/h1-2,4-7,9-10,16,20H,3,8,11H2,(H2,19,21)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-LaRoche Inc. US Patent					Assay Description The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration...				US Patent US8673950 (2014) BindingDB Entry DOI: 10.7270/Q29S1PQD
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM119141 (US8673950, 8) Show SMILES NC1=N[C@@H](CCc2ccc(Nc3ccc(cc3)C(F)(F)F)cc2)CO1 |r,t:1| Show InChI InChI=1S/C18H18F3N3O/c19-18(20,21)13-4-9-15(10-5-13)23-14-6-1-12(2-7-14)3-8-16-11-25-17(22)24-16/h1-2,4-7,9-10,16,23H,3,8,11H2,(H2,22,24)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-LaRoche Inc. US Patent					Assay Description The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration...				US Patent US8673950 (2014) BindingDB Entry DOI: 10.7270/Q29S1PQD
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM109373 (US8604061, 48) Show SMILES NC1=N[C@@H](Cc2cccc3ccccc23)CO1 |r,t:1| Show InChI InChI=1S/C14H14N2O/c15-14-16-12(9-17-14)8-11-6-3-5-10-4-1-2-7-13(10)11/h1-7,12H,8-9H2,(H2,15,16)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240677 (US9416127, 14 | US9416127, 15) Show SMILES FC(F)(F)Oc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H18F3N5O3/c21-20(22,23)31-16-7-5-15(6-8-16)28-25-11-17(27-28)19(29)26-14-3-1-13(2-4-14)18-12-24-9-10-30-18/h1-8,11,18,24H,9-10,12H2,(H,26,29)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.200	-13.8	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM109462 (US8604061, 201) Show SMILES NC1=N[C@H](CO1)c1cc(Cl)cc(Cl)c1 |r,t:1| Show InChI InChI=1S/C9H8Cl2N2O/c10-6-1-5(2-7(11)3-6)8-4-14-9(12)13-8/h1-3,8H,4H2,(H2,12,13)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240666 (US9416127, 16 | US9416127, 3) Show SMILES FC(F)Oc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H19F2N5O3/c21-20(22)30-16-7-5-15(6-8-16)27-24-11-17(26-27)19(28)25-14-3-1-13(2-4-14)18-12-23-9-10-29-18/h1-8,11,18,20,23H,9-10,12H2,(H,25,28)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	-13.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240676 (US9416127, 13) Show SMILES FC(F)(F)c1cccc(c1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H18F3N5O2/c21-20(22,23)14-2-1-3-16(10-14)28-25-11-17(27-28)19(29)26-15-6-4-13(5-7-15)18-12-24-8-9-30-18/h1-7,10-11,18,24H,8-9,12H2,(H,26,29)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	-13.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240668 (US9416127, 11 | US9416127, 5) Show SMILES Fc1cccc(c1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18FN5O2/c20-14-2-1-3-16(10-14)25-22-11-17(24-25)19(26)23-15-6-4-13(5-7-15)18-12-21-8-9-27-18/h1-7,10-11,18,21H,8-9,12H2,(H,23,26)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	-13.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190607 (US9181230, 13) Show SMILES Fc1ccc(-c2cc(n[nH]2)-c2ccc(cc2)[C@H]2CNCCO2)c(F)c1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	-13.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM167453 (US9073911, 2) Show SMILES Clc1cccc(c1)-c1cc(n[nH]1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description The TAAR1 radioligand 3[H](S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration ...				US Patent US9073911 (2015) BindingDB Entry DOI: 10.7270/Q2N29VPX
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM119193 (US8673950, 60) Show SMILES NC1=N[C@@H](CCc2ccc(Nc3ncc(cn3)C3CCC3)cc2)CO1 |r,t:1| Show InChI InChI=1S/C19H23N5O/c20-18-23-17(12-25-18)9-6-13-4-7-16(8-5-13)24-19-21-10-15(11-22-19)14-2-1-3-14/h4-5,7-8,10-11,14,17H,1-3,6,9,12H2,(H2,20,23)(H,21,22,24)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-LaRoche Inc. US Patent					Assay Description The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration...				US Patent US8673950 (2014) BindingDB Entry DOI: 10.7270/Q29S1PQD
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM119187 (US8673950, 54) Show SMILES NC1=N[C@@H](CCc2ccc(Nc3ncc(cn3)C3CC3)cc2)CO1 |r,t:1| Show InChI InChI=1S/C18H21N5O/c19-17-22-16(11-24-17)8-3-12-1-6-15(7-2-12)23-18-20-9-14(10-21-18)13-4-5-13/h1-2,6-7,9-10,13,16H,3-5,8,11H2,(H2,19,22)(H,20,21,23)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-LaRoche Inc. US Patent					Assay Description The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration...				US Patent US8673950 (2014) BindingDB Entry DOI: 10.7270/Q29S1PQD
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250218 (US10501411, Example 128 | US11697636, Example 128 ...) Show SMILES Clc1ccc(CCCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C20H23ClN2O2/c21-18-7-3-15(4-8-18)2-1-13-25-20(24)23-19-9-5-16(6-10-19)17-11-12-22-14-17/h3-10,17,22H,1-2,11-14H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Mouse: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concen...				US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250215 (US10501411, Example 125 | US11697636, Example 125 ...) Show SMILES FC(F)(F)Oc1ccc(CCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C20H21F3N2O3/c21-20(22,23)28-18-7-1-14(2-8-18)10-12-27-19(26)25-17-5-3-15(4-6-17)16-9-11-24-13-16/h1-8,16,24H,9-13H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Mouse: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concen...				US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250212 (US10501411, Example 122 | US11697636, Example 122 ...) Show SMILES FC(F)(F)c1ccc(CCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C20H21F3N2O2/c21-20(22,23)17-5-1-14(2-6-17)10-12-27-19(26)25-18-7-3-15(4-8-18)16-9-11-24-13-16/h1-8,16,24H,9-13H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Mouse: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concen...				US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250218 (US10501411, Example 128 | US11697636, Example 128 ...) Show SMILES Clc1ccc(CCCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C20H23ClN2O2/c21-18-7-3-15(4-8-18)2-1-13-25-20(24)23-19-9-5-16(6-10-19)17-11-12-22-14-17/h3-10,17,22H,1-2,11-14H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2988C4J
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250215 (US10501411, Example 125 | US11697636, Example 125 ...) Show SMILES FC(F)(F)Oc1ccc(CCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C20H21F3N2O3/c21-20(22,23)28-18-7-1-14(2-8-18)10-12-27-19(26)25-17-5-3-15(4-6-17)16-9-11-24-13-16/h1-8,16,24H,9-13H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2988C4J
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250212 (US10501411, Example 122 | US11697636, Example 122 ...) Show SMILES FC(F)(F)c1ccc(CCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C20H21F3N2O2/c21-20(22,23)17-5-1-14(2-6-17)10-12-27-19(26)25-18-7-3-15(4-8-18)16-9-11-24-13-16/h1-8,16,24H,9-13H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2988C4J
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122333 (US8729113, 57) Show SMILES NC1=N[C@@H](CCOc2ccc(Cl)c(Cl)c2)CO1 |r,t:1| Show InChI InChI=1S/C11H12Cl2N2O2/c12-9-2-1-8(5-10(9)13)16-4-3-7-6-17-11(14)15-7/h1-2,5,7H,3-4,6H2,(H2,14,15)/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	-12.1	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122298 (US8729113, 5) Show SMILES NC1=N[C@@H](CCOc2cccc(Cl)c2)CO1 |r,t:1| Show InChI InChI=1S/C11H13ClN2O2/c12-8-2-1-3-10(6-8)15-5-4-9-7-16-11(13)14-9/h1-3,6,9H,4-5,7H2,(H2,13,14)/t9-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	-12.1	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM119156 (US8673950, 23) Show SMILES NC1=N[C@@H](CCc2ccc(Nc3cc(ccn3)C(F)(F)F)cc2)CO1 |r,t:1| Show InChI InChI=1S/C17H17F3N4O/c18-17(19,20)12-7-8-22-15(9-12)23-13-4-1-11(2-5-13)3-6-14-10-25-16(21)24-14/h1-2,4-5,7-9,14H,3,6,10H2,(H2,21,24)(H,22,23)/t14-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-LaRoche Inc. US Patent					Assay Description The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concentration...				US Patent US8673950 (2014) BindingDB Entry DOI: 10.7270/Q29S1PQD
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM109564 (US8604061, 354) Show SMILES NC1=N[C@@H](COc2ccccc2F)CO1 |r,t:1| Show InChI InChI=1S/C10H11FN2O2/c11-8-3-1-2-4-9(8)14-5-7-6-15-10(12)13-7/h1-4,7H,5-6H2,(H2,12,13)/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM109408 (US8604061, 127) Show SMILES NC1=N[C@@H](CCc2ccc(Cl)c(Cl)c2)CO1 |r,t:1| Show InChI InChI=1S/C11H12Cl2N2O/c12-9-4-2-7(5-10(9)13)1-3-8-6-16-11(14)15-8/h2,4-5,8H,1,3,6H2,(H2,14,15)/t8-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250218 (US10501411, Example 128 | US11697636, Example 128 ...) Show SMILES Clc1ccc(CCCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C20H23ClN2O2/c21-18-7-3-15(4-8-18)2-1-13-25-20(24)23-19-9-5-16(6-10-19)17-11-12-22-14-17/h3-10,17,22H,1-2,11-14H2,(H,23,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	-13.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250215 (US10501411, Example 125 | US11697636, Example 125 ...) Show SMILES FC(F)(F)Oc1ccc(CCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C20H21F3N2O3/c21-20(22,23)28-18-7-1-14(2-8-18)10-12-27-19(26)25-17-5-3-15(4-6-17)16-9-11-24-13-16/h1-8,16,24H,9-13H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	-13.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250212 (US10501411, Example 122 | US11697636, Example 122 ...) Show SMILES FC(F)(F)c1ccc(CCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C20H21F3N2O2/c21-20(22,23)17-5-1-14(2-6-17)10-12-27-19(26)25-18-7-3-15(4-8-18)16-9-11-24-13-16/h1-8,16,24H,9-13H2,(H,25,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.300	-13.5	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240667 (US9416127, 4 | US9416127, 9) Show SMILES Fc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18FN5O2/c20-14-3-7-16(8-4-14)25-22-11-17(24-25)19(26)23-15-5-1-13(2-6-15)18-12-21-9-10-27-18/h1-8,11,18,21H,9-10,12H2,(H,23,26)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	-13.3	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250210 (US10501411, Example 120 | US11697636, Example 120 ...) Show SMILES Clc1ccc(CCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C19H21ClN2O2/c20-17-5-1-14(2-6-17)10-12-24-19(23)22-18-7-3-15(4-8-18)16-9-11-21-13-16/h1-8,16,21H,9-13H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	-13.3	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9452980 (2016) BindingDB Entry DOI: 10.7270/Q2X63KVF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM109528 (US8604061, 298) Show SMILES NC1=N[C@H](CO1)c1cc(Cl)ccc1Cl |r,t:1| Show InChI InChI=1S/C9H8Cl2N2O/c10-5-1-2-7(11)6(3-5)8-4-14-9(12)13-8/h1-3,8H,4H2,(H2,12,13)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122380 (US8729113, 136) Show SMILES NC1=N[C@@H](CCOc2cccc(c2)C(=O)OCc2ccccc2)CO1 |r,t:1| Show InChI InChI=1S/C19H20N2O4/c20-19-21-16(13-25-19)9-10-23-17-8-4-7-15(11-17)18(22)24-12-14-5-2-1-3-6-14/h1-8,11,16H,9-10,12-13H2,(H2,20,21)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-11.9	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240669 (US9416127, 6) Show SMILES Clc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C19H18ClN5O2/c20-14-3-7-16(8-4-14)25-22-11-17(24-25)19(26)23-15-5-1-13(2-6-15)18-12-21-9-10-27-18/h1-8,11,18,21H,9-10,12H2,(H,23,26)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	-13.3	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190621 (US9181230, 27) Show SMILES Fc1ccc(cc1)-c1cn(nn1)-c1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C18H17FN4O/c19-15-5-1-13(2-6-15)17-12-23(22-21-17)16-7-3-14(4-8-16)18-11-20-9-10-24-18/h1-8,12,18,20H,9-11H2/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-13.3	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM60837 (US9181230, 9) Show SMILES Clc1cccc(c1)-c1cc(n[nH]1)-c1ccc(cc1)C1CNCCO1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-13.3	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM109446 (US8604061, 178) Show SMILES NC1=N[C@H](CO1)c1cc(F)cc(Cl)c1 |r,t:1| Show InChI InChI=1S/C9H8ClFN2O/c10-6-1-5(2-7(11)3-6)8-4-14-9(12)13-8/h1-3,8H,4H2,(H2,12,13)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250210 (US10501411, Example 120 | US11697636, Example 120 ...) Show SMILES Clc1ccc(CCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C19H21ClN2O2/c20-17-5-1-14(2-6-17)10-12-24-19(23)22-18-7-3-15(4-8-18)16-9-11-21-13-16/h1-8,16,21H,9-13H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem		0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2988C4J
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240673 (US9416127, 10) Show SMILES FC(F)(F)c1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H18F3N5O2/c21-20(22,23)14-3-7-16(8-4-14)28-25-11-17(27-28)19(29)26-15-5-1-13(2-6-15)18-12-24-9-10-30-18/h1-8,11,18,24H,9-10,12H2,(H,26,29)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	-13.3	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM109390 (US8604061, 103) Show SMILES NC1=N[C@H](CO1)c1ccc2ccccc2c1 |r,t:1| Show InChI InChI=1S/C13H12N2O/c14-13-15-12(8-16-13)11-6-5-9-3-1-2-4-10(9)7-11/h1-7,12H,8H2,(H2,14,15)/t12-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM240677 (US9416127, 14 | US9416127, 15) Show SMILES FC(F)(F)Oc1ccc(cc1)-n1ncc(n1)C(=O)Nc1ccc(cc1)[C@H]1CNCCO1 |r| Show InChI InChI=1S/C20H18F3N5O3/c21-20(22,23)31-16-7-5-15(6-8-16)28-25-11-17(27-28)19(29)26-14-3-1-13(2-4-14)18-12-24-9-10-30-18/h1-8,11,18,24H,9-10,12H2,(H,26,29)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	-13.3	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9416127 (2016) BindingDB Entry DOI: 10.7270/Q22R3QK8
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM122318 (US8729113, 30) Show SMILES NC1=N[C@@H](CCC2(CC2)c2ccc(Cl)cc2)CO1 |r,t:1| Show InChI InChI=1S/C14H17ClN2O/c15-11-3-1-10(2-4-11)14(7-8-14)6-5-12-9-18-13(16)17-12/h1-4,12H,5-9H2,(H2,16,17)/t12-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-11.9	n/a	n/a	n/a	n/a	n/a	n/a	4
Hoffmann-La Roche Inc. US Patent					Assay Description Binding assay was performed at 4 C. in a final volume of 1 ml, and with an incubation time of 30 min. The radioligand [3H]-rac-2-(1,2,3,4-tetrahydro-...				US Patent US8729113 (2014) BindingDB Entry DOI: 10.7270/Q20Z71ZW
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM250210 (US10501411, Example 120 | US11697636, Example 120 ...) Show SMILES Clc1ccc(CCOC(=O)Nc2ccc(cc2)C2CCNC2)cc1 Show InChI InChI=1S/C19H21ClN2O2/c20-17-5-1-14(2-6-17)10-12-24-19(23)22-18-7-3-15(4-8-18)16-9-11-21-13-16/h1-8,16,21H,9-13H2,(H,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Mouse: The TAAR1 radioligand 3[H]-(S)-4-[(ethyl-phenyl-amino)-methyl]-4,5-dihydro-oxazol-2-ylamine (described in WO 2008/098857) was used at a concen...				US Patent US10501411 (2019) BindingDB Entry DOI: 10.7270/Q27S7R5Q
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM190602 (US9181230, 8) Show SMILES Clc1ccc(cc1)-c1cc(n[nH]1)-c1ccc(cc1)[C@@H]1CNCCO1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-13.3	n/a	n/a	n/a	n/a	n/a	7.4	37
Hoffmann-La Roche Inc. US Patent					Assay Description HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, h...				US Patent US9181230 (2015) BindingDB Entry DOI: 10.7270/Q2930S0Z
					More data for this Ligand-Target Pair
Trace amine-associated receptor 1 (Mus musculus (Mouse))	BDBM109580 (US8604061, 296) Show SMILES NC1=N[C@H](CO1)c1ccc(Cl)cc1Cl |r,t:1| Show InChI InChI=1S/C9H8Cl2N2O/c10-5-1-2-6(7(11)3-5)8-4-14-9(12)13-8/h1-3,8H,4H2,(H2,12,13)/t8-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description Radioligand binding assay using TAAR1.				US Patent US8604061 (2013) BindingDB Entry DOI: 10.7270/Q22V2DRF
					More data for this Ligand-Target Pair

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