Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM108221 (5-(hydroxymethyl)-2-[3-(4-phenylphenyl)propyl]- 5H...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | 10.6 | 37 |
Nankai University | Assay Description In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min.... | Chembiochem 14: 1239-47 (2013) Article DOI: 10.1002/cbic.201300197 BindingDB Entry DOI: 10.7270/Q2NS0SHP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM108222 (2-[3-(4-cyclohexylphenyl)propyl]-5-(hydroxymethyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 52 | n/a | n/a | n/a | n/a | 10.6 | 37 |
Nankai University | Assay Description In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min.... | Chembiochem 14: 1239-47 (2013) Article DOI: 10.1002/cbic.201300197 BindingDB Entry DOI: 10.7270/Q2NS0SHP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM60585 (2-(3'-Fluorophenyl)-7-methyl-1H-benzo[d]imidazole ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 165 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA (UiTM), Puncak Alam Campus | Assay Description The 135 無 of 50 mM phosphate saline buffer pH (6.8), solution of enzyme (20 無), and 20 無 of test sample with 70% DMSO was added to 96-well plate. ... | Bioorg Chem 65: 100-9 (2016) Article DOI: 10.1016/j.bioorg.2016.02.004 BindingDB Entry DOI: 10.7270/Q24B303S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM108219 (5-(hydroxymethyl)-2-[3-(4-methylphenyl)propyl]- 5H...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 280 | n/a | n/a | n/a | n/a | 10.6 | 37 |
Nankai University | Assay Description In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min.... | Chembiochem 14: 1239-47 (2013) Article DOI: 10.1002/cbic.201300197 BindingDB Entry DOI: 10.7270/Q2NS0SHP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM108220 (5-(hydroxymethyl)-2-[3-(4-methoxyphenyl)propyl]- 5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 300 | n/a | n/a | n/a | n/a | 10.6 | 37 |
Nankai University | Assay Description In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min.... | Chembiochem 14: 1239-47 (2013) Article DOI: 10.1002/cbic.201300197 BindingDB Entry DOI: 10.7270/Q2NS0SHP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM108216 (5-(hydroxymethyl)-2-(2-phenylethyl)-5H,6H,7H,8H- i...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 570 | n/a | n/a | n/a | n/a | 10.6 | 37 |
Nankai University | Assay Description In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min.... | Chembiochem 14: 1239-47 (2013) Article DOI: 10.1002/cbic.201300197 BindingDB Entry DOI: 10.7270/Q2NS0SHP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM108223 (2-[3-(4-fluorophenyl)propyl]-5-(hydroxymethyl)- 5H...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 730 | n/a | n/a | n/a | n/a | 10.6 | 37 |
Nankai University | Assay Description In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min.... | Chembiochem 14: 1239-47 (2013) Article DOI: 10.1002/cbic.201300197 BindingDB Entry DOI: 10.7270/Q2NS0SHP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM108218 (5-(hydroxymethyl)-2-octyl-5H,6H,7H,8H-imidazo[1,2-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 970 | n/a | n/a | n/a | n/a | 10.6 | 37 |
Nankai University | Assay Description In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min.... | Chembiochem 14: 1239-47 (2013) Article DOI: 10.1002/cbic.201300197 BindingDB Entry DOI: 10.7270/Q2NS0SHP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM108224 (N-phenyl-4-[6,7,8-trihydroxy-5-(hydroxymethyl)- 5H...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | 10.6 | 37 |
Nankai University | Assay Description In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min.... | Chembiochem 14: 1239-47 (2013) Article DOI: 10.1002/cbic.201300197 BindingDB Entry DOI: 10.7270/Q2NS0SHP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM178004 (2-(3-((3-(trifluoromethyl)benzyl)oxy)phenyl)-4H-ch...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA | Assay Description The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi... | Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM50438504 (CHEMBL2414818) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xi'an Jiaotong University Curated by ChEMBL | Assay Description Inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as 4-nitrophenol release from 4-nitrophenyl alpha-D-glucopyranoside preincubated fo... | Bioorg Med Chem 21: 5442-50 (2013) Article DOI: 10.1016/j.bmc.2013.06.002 BindingDB Entry DOI: 10.7270/Q2HD7X24 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM173530 ((E)-N'-(3,4,5-trihydroxybenzylidene)-1H-indole...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA (UiTM) | Assay Description The 135 無 of 50 mM phosphate saline buffer pH (6.8) was added in the 96-well plate and 20 無 of test sample with 70% DMSO added into the wells. The ... | Bioorg Chem 63: 24-35 (2015) Article DOI: 10.1016/j.bioorg.2015.09.001 BindingDB Entry DOI: 10.7270/Q24Q7SSK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM150768 (2-(5H-[1,2,4]triazino[5,6-b]indol-3-ylthio)-1-(3-h...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.46E+3 | n/a | n/a | n/a | n/a | n/a | 310.15 |
Hazara University | Assay Description Typically, α-glucosidase activity was assayed in 50 mM phosphate buffer (pH 6.8) containing 5% v/v DMSO and PNP glycoside was used as a substrat... | Bioorg Chem 58: 81-7 (2015) Article DOI: 10.1016/j.bioorg.2014.12.001 BindingDB Entry DOI: 10.7270/Q2JQ0ZR8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM222221 (3-(4-(4,5-diphenyl-1H-imidazol-2-yl)-1-phenyl-1H-p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.78E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the Punjab; Kinnaird College for Women | Assay Description At 37 蚓, after incubation of 10 min of a reaction mixture solution of 70 μL (50 mM) phosphate buffer of 6.8 pH, 10 μL (0.5 mM) of a test c... | Bioorg Chem 71: 102-109 (2017) Article DOI: 10.1016/j.bioorg.2017.01.017 BindingDB Entry DOI: 10.7270/Q2Z89B86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM222222 (6-Bromo-3-(4-(4,5-diphenyl-1H-imidazol-2-yl)-1-phe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the Punjab; Kinnaird College for Women | Assay Description At 37 蚓, after incubation of 10 min of a reaction mixture solution of 70 μL (50 mM) phosphate buffer of 6.8 pH, 10 μL (0.5 mM) of a test c... | Bioorg Chem 71: 102-109 (2017) Article DOI: 10.1016/j.bioorg.2017.01.017 BindingDB Entry DOI: 10.7270/Q2Z89B86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM108217 (2-(3,3-dimethylbutyl)-5-(hydroxymethyl)- 5H,6H,7H,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.42E+3 | n/a | n/a | n/a | n/a | 10.6 | 37 |
Nankai University | Assay Description In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min.... | Chembiochem 14: 1239-47 (2013) Article DOI: 10.1002/cbic.201300197 BindingDB Entry DOI: 10.7270/Q2NS0SHP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM178010 (2-(3-((2,3-difluorobenzyl)oxy)phenyl)-4H-chromen-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.49E+3 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA | Assay Description The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi... | Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM50063756 (CHEMBL3397482) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology) Curated by ChEMBL | Assay Description Inhibition of bakers yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate after 30 mins by spectrophotometry | Bioorg Med Chem Lett 25: 1471-5 (2015) Article DOI: 10.1016/j.bmcl.2015.02.031 BindingDB Entry DOI: 10.7270/Q2K35WCH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM179781 (2-(2'-Chlorophenyl)-7-methyl-1H-benzo[d]imidaz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA (UiTM), Puncak Alam Campus | Assay Description The 135 無 of 50 mM phosphate saline buffer pH (6.8), solution of enzyme (20 無), and 20 無 of test sample with 70% DMSO was added to 96-well plate. ... | Bioorg Chem 65: 100-9 (2016) Article DOI: 10.1016/j.bioorg.2016.02.004 BindingDB Entry DOI: 10.7270/Q24B303S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM178004 (2-(3-((3-(trifluoromethyl)benzyl)oxy)phenyl)-4H-ch...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.45E+3 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA | Assay Description The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi... | Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM50438503 (CHEMBL2414819) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Xi'an Jiaotong University Curated by ChEMBL | Assay Description Inhibition of Saccharomyces cerevisiae alpha-glucosidase assessed as 4-nitrophenol release from 4-nitrophenyl alpha-D-glucopyranoside preincubated fo... | Bioorg Med Chem 21: 5442-50 (2013) Article DOI: 10.1016/j.bmc.2013.06.002 BindingDB Entry DOI: 10.7270/Q2HD7X24 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM222219 (4-(4,5-Diphenyl-1H-imidazol-2-yl)-1-(4-nitrophenyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the Punjab; Kinnaird College for Women | Assay Description At 37 蚓, after incubation of 10 min of a reaction mixture solution of 70 μL (50 mM) phosphate buffer of 6.8 pH, 10 μL (0.5 mM) of a test c... | Bioorg Chem 71: 102-109 (2017) Article DOI: 10.1016/j.bioorg.2017.01.017 BindingDB Entry DOI: 10.7270/Q2Z89B86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM175324 ((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.40E+3 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA (UiTM) | Assay Description The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ... | Bioorg Chem 64: 29-36 (2016) Article DOI: 10.1016/j.bioorg.2015.11.006 BindingDB Entry DOI: 10.7270/Q2W37V2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM175315 ((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.44E+3 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA (UiTM) | Assay Description The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ... | Bioorg Chem 64: 29-36 (2016) Article DOI: 10.1016/j.bioorg.2015.11.006 BindingDB Entry DOI: 10.7270/Q2W37V2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM175317 ((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.44E+3 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA (UiTM) | Assay Description The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ... | Bioorg Chem 64: 29-36 (2016) Article DOI: 10.1016/j.bioorg.2015.11.006 BindingDB Entry DOI: 10.7270/Q2W37V2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM178007 (2-(3-((3-((trifluoromethyl)thio)benzyl)oxy)phenyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.66E+3 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA | Assay Description The α-glucosidase inhibition assay had been carried out using baker窺 yeast a-glucosidase (EC 3.2.1.20) and p-nitrophenyl-α-D-glucopyranosi... | Chem Biol Drug Des 87: 361-73 (2016) Article DOI: 10.1111/cbdd.12666 BindingDB Entry DOI: 10.7270/Q2HQ3XPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM175309 ((E)-N'-(2,5-dihydroxybenzylidene)-4-(5,6-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.74E+3 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA (UiTM) | Assay Description The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ... | Bioorg Chem 64: 29-36 (2016) Article DOI: 10.1016/j.bioorg.2015.11.006 BindingDB Entry DOI: 10.7270/Q2W37V2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM175311 ((E)-N'-(2,4-dihydroxybenzylidene)-4-(5,6-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.74E+3 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA (UiTM) | Assay Description The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ... | Bioorg Chem 64: 29-36 (2016) Article DOI: 10.1016/j.bioorg.2015.11.006 BindingDB Entry DOI: 10.7270/Q2W37V2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM23406 ((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 9.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
King Abdulaziz University | Assay Description α-Glucosidase inhibitory activity was evaluated at 37 蚓, by using 0.1M phosphatebuffer (pH6.8) [28]. The enzyme(EC3.2.1.20, Saccharomyces cerev... | Bioorg Chem 65: 61-72 (2016) Article DOI: 10.1016/j.bioorg.2016.01.008 BindingDB Entry DOI: 10.7270/Q2V123JW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM175310 ((E)-N'-(2,3-dihydroxybenzylidene)-4-(5,6-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.99E+3 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA (UiTM) | Assay Description The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ... | Bioorg Chem 64: 29-36 (2016) Article DOI: 10.1016/j.bioorg.2015.11.006 BindingDB Entry DOI: 10.7270/Q2W37V2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM222214 (3-(4-Bromophenyl)-4-(4,5-diphenyl-1H-imidazol-2-yl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the Punjab; Kinnaird College for Women | Assay Description At 37 蚓, after incubation of 10 min of a reaction mixture solution of 70 μL (50 mM) phosphate buffer of 6.8 pH, 10 μL (0.5 mM) of a test c... | Bioorg Chem 71: 102-109 (2017) Article DOI: 10.1016/j.bioorg.2017.01.017 BindingDB Entry DOI: 10.7270/Q2Z89B86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM50063761 (CHEMBL3397478) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.21E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology) Curated by ChEMBL | Assay Description Inhibition of bakers yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate after 30 mins by spectrophotometry | Bioorg Med Chem Lett 25: 1471-5 (2015) Article DOI: 10.1016/j.bmcl.2015.02.031 BindingDB Entry DOI: 10.7270/Q2K35WCH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM175312 ((E)-N'-(3,4-dihydroxybenzylidene)-4-(5,6-dimet...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA (UiTM) | Assay Description The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ... | Bioorg Chem 64: 29-36 (2016) Article DOI: 10.1016/j.bioorg.2015.11.006 BindingDB Entry DOI: 10.7270/Q2W37V2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM108225 (2,2-dimethyl-N-phenyl-5-[6,7,8-trihydroxy-5- (hydr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.28E+4 | n/a | n/a | n/a | n/a | 10.6 | 37 |
Nankai University | Assay Description In a 96-well plates, 10µL of commercial enzyme solutions without (control) or with 20µL of inhibitor were incubated at 37°C for 5 min.... | Chembiochem 14: 1239-47 (2013) Article DOI: 10.1002/cbic.201300197 BindingDB Entry DOI: 10.7270/Q2NS0SHP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM222217 (4-(4,5-Diphenyl-1H-imidazol-2-yl)-3-(3-nitrophenyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.28E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the Punjab; Kinnaird College for Women | Assay Description At 37 蚓, after incubation of 10 min of a reaction mixture solution of 70 μL (50 mM) phosphate buffer of 6.8 pH, 10 μL (0.5 mM) of a test c... | Bioorg Chem 71: 102-109 (2017) Article DOI: 10.1016/j.bioorg.2017.01.017 BindingDB Entry DOI: 10.7270/Q2Z89B86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM222213 (3-(4-Chlorophenyl)-4-(4,5-diphenyl-1H-imidazol-2-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.32E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the Punjab; Kinnaird College for Women | Assay Description At 37 蚓, after incubation of 10 min of a reaction mixture solution of 70 μL (50 mM) phosphate buffer of 6.8 pH, 10 μL (0.5 mM) of a test c... | Bioorg Chem 71: 102-109 (2017) Article DOI: 10.1016/j.bioorg.2017.01.017 BindingDB Entry DOI: 10.7270/Q2Z89B86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM173549 (1-(4-(bis(4-Hydroxy-2-oxo-2H-chromen-3-yl)methyl)p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.35E+4 | n/a | n/a | n/a | n/a | 6.8 | 37 |
Universiti Teknologi MARA | Assay Description The enzyme inhibition was evaluated according to the method previously reported by Taha et al. with slight modification. Various concentration of tes... | Bioorg Chem 63: 36-44 (2015) Article DOI: 10.1016/j.bioorg.2015.09.004 BindingDB Entry DOI: 10.7270/Q2125RD0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM175329 ((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.51E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA (UiTM) | Assay Description The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ... | Bioorg Chem 64: 29-36 (2016) Article DOI: 10.1016/j.bioorg.2015.11.006 BindingDB Entry DOI: 10.7270/Q2W37V2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM50203367 (CHEMBL3891396) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.52E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jishou University Curated by ChEMBL | Assay Description Inhibition of bakers yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate incubated for 15 mins followed by substrate add... | Bioorg Med Chem Lett 26: 5719-5723 (2016) Article DOI: 10.1016/j.bmcl.2016.10.057 BindingDB Entry DOI: 10.7270/Q2SF2Z4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM50063760 (CHEMBL3397479) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.57E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology) Curated by ChEMBL | Assay Description Inhibition of bakers yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate after 30 mins by spectrophotometry | Bioorg Med Chem Lett 25: 1471-5 (2015) Article DOI: 10.1016/j.bmcl.2015.02.031 BindingDB Entry DOI: 10.7270/Q2K35WCH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM50063757 (CHEMBL3397481) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Key Laboratory of Industrial Fermentation Microbiology (Tianjin University of Science and Technology) Curated by ChEMBL | Assay Description Inhibition of bakers yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate after 30 mins by spectrophotometry | Bioorg Med Chem Lett 25: 1471-5 (2015) Article DOI: 10.1016/j.bmcl.2015.02.031 BindingDB Entry DOI: 10.7270/Q2K35WCH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM179777 (2-(2'-Hydroxyphenyl)-7-methyl-1H-benzo[d]imida...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.61E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA (UiTM), Puncak Alam Campus | Assay Description The 135 無 of 50 mM phosphate saline buffer pH (6.8), solution of enzyme (20 無), and 20 無 of test sample with 70% DMSO was added to 96-well plate. ... | Bioorg Chem 65: 100-9 (2016) Article DOI: 10.1016/j.bioorg.2016.02.004 BindingDB Entry DOI: 10.7270/Q24B303S | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM50203410 (CHEMBL3901489) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.70E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jishou University Curated by ChEMBL | Assay Description Inhibition of bakers yeast alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate incubated for 15 mins followed by substrate add... | Bioorg Med Chem Lett 26: 5719-5723 (2016) Article DOI: 10.1016/j.bmcl.2016.10.057 BindingDB Entry DOI: 10.7270/Q2SF2Z4C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM222218 (3-([1,1'-Biphenyl]-4-yl)-4-(4,5-diphenyl-1H-im...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the Punjab; Kinnaird College for Women | Assay Description At 37 蚓, after incubation of 10 min of a reaction mixture solution of 70 μL (50 mM) phosphate buffer of 6.8 pH, 10 μL (0.5 mM) of a test c... | Bioorg Chem 71: 102-109 (2017) Article DOI: 10.1016/j.bioorg.2017.01.017 BindingDB Entry DOI: 10.7270/Q2Z89B86 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM175320 ((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.82E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA (UiTM) | Assay Description The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ... | Bioorg Chem 64: 29-36 (2016) Article DOI: 10.1016/j.bioorg.2015.11.006 BindingDB Entry DOI: 10.7270/Q2W37V2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM152619 ((E)-2,6-Di-t-butyl-4-((2-(4-(4-Chlorophenyl)thiazo...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.82E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Hazara University | Assay Description Total volume of 100 無 reaction mixture contained 70 無 50 mM phosphate buffer pH 6.8, 10 無 test compound (0.5 mM in methanol) followed by the addit... | Bioorg Chem 62: 15-21 (2015) Article DOI: 10.1016/j.bioorg.2015.06.006 BindingDB Entry DOI: 10.7270/Q24B302B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM50445973 (CHEMBL3103095) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.82E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of the Punjab Curated by ChEMBL | Assay Description Inhibition of Saccharomyces cerevisiae alpha-glucosidase using p-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 10 mins measured a... | Bioorg Med Chem 22: 1195-200 (2014) Article DOI: 10.1016/j.bmc.2013.12.024 BindingDB Entry DOI: 10.7270/Q2F1916H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM175321 ((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.83E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA (UiTM) | Assay Description The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ... | Bioorg Chem 64: 29-36 (2016) Article DOI: 10.1016/j.bioorg.2015.11.006 BindingDB Entry DOI: 10.7270/Q2W37V2M | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM222282 (N-(3-Chlorophenyl)-6-(3,5-dimethyl-4-nitro-1H-pyra...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.93E+4 | n/a | n/a | n/a | n/a | 6.8 | 37 |
University of the Punjab | Assay Description The enzyme assays were done in the initial linear parts of the assay curve with suitable positive and negative controls (data not shown). A total of ... | Bioorg Chem 71: 170-180 (2017) Article DOI: 10.1016/j.bioorg.2017.02.003 BindingDB Entry DOI: 10.7270/Q29G5KNP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oligo-1,6-glucosidase IMA1 (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM175330 ((E)-4-(5,6-dimethyl-1H-benzo[d]imidazol-2-yl)-N...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.94E+4 | n/a | n/a | n/a | n/a | 6.8 | n/a |
Universiti Teknologi MARA (UiTM) | Assay Description The enzyme inhibition was evaluated according to the method previously reported by Rahim et al. [25] with slight modification. Various concentration ... | Bioorg Chem 64: 29-36 (2016) Article DOI: 10.1016/j.bioorg.2015.11.006 BindingDB Entry DOI: 10.7270/Q2W37V2M | |||||||||||
More data for this Ligand-Target Pair |
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