Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM21397 (8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 0.0930 | n/a | n/a | n/a | n/a | n/a |
Universita degli Studi di Bari | Assay Description IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti... | J Med Chem 50: 4214-21 (2007) Article DOI: 10.1021/jm070487n BindingDB Entry DOI: 10.7270/Q20000CJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50016786 ((R)-2-Fluoro-6-methyl-5,6,6a,7-tetrahydro-4H-diben...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Compound was evaluated for the ability to displace [3H]-spiperone at Dopamine receptor D2 in porcine anterior pituitary gland as low affinity state | J Med Chem 32: 1198-201 (1989) BindingDB Entry DOI: 10.7270/Q2Q23Z7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50016785 ((R)-2-Amino-6-methyl-5,6,6a,7-tetrahydro-4H-dibenz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Compound was evaluated for the ability to displace [3H]-spiperone at Dopamine receptor D2 in porcine anterior pituitary gland as high affinity state | J Med Chem 32: 1198-201 (1989) BindingDB Entry DOI: 10.7270/Q2Q23Z7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | DrugBank PubMed | n/a | n/a | n/a | 127 | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Compound was evaluated for the ability to displace [3H]-spiperone at Dopamine receptor D2 in porcine anterior pituitary gland as low affinity state | J Med Chem 32: 1198-201 (1989) BindingDB Entry DOI: 10.7270/Q2Q23Z7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50010696 ((R)-2-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 6.80 | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Compound was evaluated for the ability to displace [3H]-spiperone at Dopamine receptor D2 in porcine anterior pituitary gland as high affinity state | J Med Chem 32: 1198-201 (1989) BindingDB Entry DOI: 10.7270/Q2Q23Z7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50010696 ((R)-2-Bromo-6-methyl-5,6,6a,7-tetrahydro-4H-dibenz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 728 | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Compound was evaluated for the ability to displace [3H]-spiperone at Dopamine receptor D2 in porcine anterior pituitary gland as low affinity state | J Med Chem 32: 1198-201 (1989) BindingDB Entry DOI: 10.7270/Q2Q23Z7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50016786 ((R)-2-Fluoro-6-methyl-5,6,6a,7-tetrahydro-4H-diben...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 0.430 | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Compound was evaluated for the ability to displace [3H]-spiperone at dopamine receptor in porcine anterior pituitary gland as high affinity state | J Med Chem 32: 1198-201 (1989) BindingDB Entry DOI: 10.7270/Q2Q23Z7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | DrugBank PubMed | n/a | n/a | n/a | 0.660 | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Compound was evaluated for the ability to displace [3H]-spiperone at Dopamine receptor D2 in porcine anterior pituitary gland as high affinity state | J Med Chem 32: 1198-201 (1989) BindingDB Entry DOI: 10.7270/Q2Q23Z7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50010698 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Compound was evaluated for the ability to displace [3H]-spiperone at Dopamine receptor D2 in porcine anterior pituitary gland as high affinity state | J Med Chem 32: 1198-201 (1989) BindingDB Entry DOI: 10.7270/Q2Q23Z7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50016785 ((R)-2-Amino-6-methyl-5,6,6a,7-tetrahydro-4H-dibenz...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Compound was evaluated for the ability to displace [3H]-spiperone at Dopamine receptor D2 in porcine anterior pituitary gland as high affinity state | J Med Chem 32: 1198-201 (1989) BindingDB Entry DOI: 10.7270/Q2Q23Z7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083509 (CHEMBL3423402) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 7.00E+3 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as low affinity constant aft... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083510 (CHEMBL3423411) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 400 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant af... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083540 (CHEMBL3423410) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant af... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083544 (CHEMBL3423409) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant af... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083546 (CHEMBL3423408) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant af... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083550 (CHEMBL3423407) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant af... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083551 (CHEMBL3423406) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant af... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083554 (CHEMBL3423405) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant af... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083555 (CHEMBL3423404) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 4.70E+3 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant af... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083558 (CHEMBL3423403) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant af... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083509 (CHEMBL3423402) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant af... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083559 (CHEMBL3423401) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant af... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083560 (CHEMBL3423400) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as high affinity constant af... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083558 (CHEMBL3423403) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as low affinity constant aft... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083554 (CHEMBL3423405) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as low affinity constant aft... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083551 (CHEMBL3423406) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as low affinity constant aft... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083550 (CHEMBL3423407) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as low affinity constant aft... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083546 (CHEMBL3423408) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as low affinity constant aft... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083540 (CHEMBL3423410) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as low affinity constant aft... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50083510 (CHEMBL3423411) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Displacement of [3H]-YM09151-2 from dopamine D2 receptor (unknown origin) expressed in sheep striatum membranes assessed as low affinity constant aft... | Eur J Med Chem 97: 173-80 (2015) Article DOI: 10.1016/j.ejmech.2015.04.052 BindingDB Entry DOI: 10.7270/Q2K64KST | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50214401 ((6aR,9R)-N-((S)-1-((S)-1-((S)-2-carbamoylpyrrolidi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a | n/a |
Institut d'Investigacions Biomèdiques August Pi i Curated by ChEMBL | Assay Description Displacement of [3H]YM 09151-2 from dopamine D2 receptor in lamb striatum membrane after 2 hrs | J Med Chem 50: 3062-9 (2007) Article DOI: 10.1021/jm060947x BindingDB Entry DOI: 10.7270/Q2BP02GQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50214403 ((6aR,9R)-N-((S)-1-((S)-1-(3-carbamoylpiperidin-1-y...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a |
Institut d'Investigacions Biomèdiques August Pi i Curated by ChEMBL | Assay Description Displacement of [3H]YM 09151-2 from dopamine D2 receptor in lamb striatum membrane after 2 hrs | J Med Chem 50: 3062-9 (2007) Article DOI: 10.1021/jm060947x BindingDB Entry DOI: 10.7270/Q2BP02GQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50214406 ((6aR,9R)-N-((S)-1-((S)-1-((S)-2-carbamoylpyrrolidi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a |
Institut d'Investigacions Biomèdiques August Pi i Curated by ChEMBL | Assay Description Displacement of [3H]YM 09151-2 from dopamine D2 receptor in lamb striatum membrane after 2 hrs | J Med Chem 50: 3062-9 (2007) Article DOI: 10.1021/jm060947x BindingDB Entry DOI: 10.7270/Q2BP02GQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50214409 ((6aR,9R)-N-((S)-1-((S)-1-((S)-2-carbamoylindolin-1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a |
Institut d'Investigacions Biomèdiques August Pi i Curated by ChEMBL | Assay Description Displacement of [3H]YM 09151-2 from dopamine D2 receptor in lamb striatum membrane after 2 hrs | J Med Chem 50: 3062-9 (2007) Article DOI: 10.1021/jm060947x BindingDB Entry DOI: 10.7270/Q2BP02GQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM21397 (8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a |
Florida A&M University Curated by ChEMBL | Assay Description Binding affinity to dopamine D2 receptor in human brain caudate nucleus | Bioorg Med Chem 24: 3671-9 (2016) Article DOI: 10.1016/j.bmc.2016.06.011 BindingDB Entry DOI: 10.7270/Q2W66NPV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50019293 (1-(1-{3-[Bis-(4-fluoro-phenyl)-amino]-propyl}-pipe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a |
Ewha Womans University Curated by ChEMBL | Assay Description Inhibition of dopamine D2 receptor | Bioorg Med Chem 18: 5938-44 (2010) Article DOI: 10.1016/j.bmc.2010.06.082 BindingDB Entry DOI: 10.7270/Q2ZS2WQ5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50343785 (CHEMBL1774386 | N-(4-(4-(2,3-Dichlorophenyl)pipera...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.0300 | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Binding affinity to wild type human dopamine D2 receptor expressed in HEK293 cells | J Med Chem 54: 3581-94 (2011) Article DOI: 10.1021/jm200288r BindingDB Entry DOI: 10.7270/Q25M661K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50004813 (8-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-3-methyl-1-phe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | 0.0970 | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Affinity constant of compound was evaluated in human brain | J Med Chem 31: 1039-43 (1988) BindingDB Entry DOI: 10.7270/Q2C24X1V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50004822 ((R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a | n/a |
VA Medical Center Curated by ChEMBL | Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D2A expressed in COS7 cells | J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50007422 ((+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a |
VA Medical Center Curated by ChEMBL | Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D2A expressed in COS7 cells | J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | DrugBank Article PubMed | n/a | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a |
VA Medical Center Curated by ChEMBL | Assay Description Equilibrium dissociation constant against recombinant Dopamine receptor D2A expressed in COS7 cells | J Med Chem 39: 850-9 (1996) Article DOI: 10.1021/jm950447w BindingDB Entry DOI: 10.7270/Q2XG9RT3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50423465 (ERGOLINE) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Binding affinity to human dopamine D2 receptor | Bioorg Med Chem Lett 18: 979-82 (2008) Article DOI: 10.1016/j.bmcl.2007.12.030 BindingDB Entry DOI: 10.7270/Q2WQ053B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50423462 (CHEMBL251835) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 126 | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for BioMedical Research Curated by ChEMBL | Assay Description Binding affinity to human dopamine D2 receptor | Bioorg Med Chem Lett 18: 979-82 (2008) Article DOI: 10.1016/j.bmcl.2007.12.030 BindingDB Entry DOI: 10.7270/Q2WQ053B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50530671 (CHEMBL4482896) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 141 | n/a | n/a | n/a | n/a | n/a |
University of Nottingham Curated by ChEMBL | Assay Description Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assay | J Med Chem 62: 9488-9520 (2019) Article DOI: 10.1021/acs.jmedchem.9b00864 BindingDB Entry DOI: 10.7270/Q2NP27WQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50010289 ((R)6-(Phenethyl-propyl-amino)-5,6,7,8-tetrahydro-n...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a |
University of Nottingham Curated by ChEMBL | Assay Description Binding affinity to SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assay | J Med Chem 62: 9488-9520 (2019) Article DOI: 10.1021/acs.jmedchem.9b00864 BindingDB Entry DOI: 10.7270/Q2NP27WQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50530673 (CHEMBL4453290) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a |
University of Nottingham Curated by ChEMBL | Assay Description Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assay | J Med Chem 62: 9488-9520 (2019) Article DOI: 10.1021/acs.jmedchem.9b00864 BindingDB Entry DOI: 10.7270/Q2NP27WQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50530674 (CHEMBL4579971) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a |
University of Nottingham Curated by ChEMBL | Assay Description Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assay | J Med Chem 62: 9488-9520 (2019) Article DOI: 10.1021/acs.jmedchem.9b00864 BindingDB Entry DOI: 10.7270/Q2NP27WQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50362868 (CHEMBL1940404) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.794 | n/a | n/a | n/a | n/a | n/a |
University of Nottingham Curated by ChEMBL | Assay Description Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assay | J Med Chem 62: 9488-9520 (2019) Article DOI: 10.1021/acs.jmedchem.9b00864 BindingDB Entry DOI: 10.7270/Q2NP27WQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50530676 (CHEMBL4528835) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 0.145 | n/a | n/a | n/a | n/a | n/a |
University of Nottingham Curated by ChEMBL | Assay Description Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assay | J Med Chem 62: 9488-9520 (2019) Article DOI: 10.1021/acs.jmedchem.9b00864 BindingDB Entry DOI: 10.7270/Q2NP27WQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50530677 (CHEMBL4568709) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 7.60 | n/a | n/a | n/a | n/a | n/a |
University of Nottingham Curated by ChEMBL | Assay Description Displacement of PPHT-red from SNAP-tagged human D2LR expressed in CHOK1 cell membranes by TR-FRET assay | J Med Chem 62: 9488-9520 (2019) Article DOI: 10.1021/acs.jmedchem.9b00864 BindingDB Entry DOI: 10.7270/Q2NP27WQ | |||||||||||
More data for this Ligand-Target Pair |
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