Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kinesin-like protein KIF11 [1-973] (Homo sapiens (Human)) | BDBM115177 ((−)-Ethyl 2-[2-(2-benzoyl-5,6-dibromo-1H-ben...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.37E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Santiago de Compostela, Jenaro de la Fuente s/n, Campus Vida, Santiago de Compostela 15782 (Spain) | Assay Description The IC50 measurements were done using a microtubule-activated ATPase kinetic assay according to the manufacturer's instructions. Reactions were ... | Chembiochem 15: 1471-80 (2014) Article DOI: 10.1002/cbic.201402089 BindingDB Entry DOI: 10.7270/Q29W0D5K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF11 [1-973] (Homo sapiens (Human)) | BDBM115175 ((−)-Ethyl 2-[2-(2-benzoyl-5,6-dibromo-1H-ben...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Santiago de Compostela, Jenaro de la Fuente s/n, Campus Vida, Santiago de Compostela 15782 (Spain) | Assay Description The IC50 measurements were done using a microtubule-activated ATPase kinetic assay according to the manufacturer's instructions. Reactions were ... | Chembiochem 15: 1471-80 (2014) Article DOI: 10.1002/cbic.201402089 BindingDB Entry DOI: 10.7270/Q29W0D5K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF11 [1-973] (Homo sapiens (Human)) | BDBM115164 (Ethyl 2-[2-(2-benzyl-5,6-dichloro-1H-benzo[d]imida...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Santiago de Compostela, Jenaro de la Fuente s/n, Campus Vida, Santiago de Compostela 15782 (Spain) | Assay Description The IC50 measurements were done using a microtubule-activated ATPase kinetic assay according to the manufacturer's instructions. Reactions were ... | Chembiochem 15: 1471-80 (2014) Article DOI: 10.1002/cbic.201402089 BindingDB Entry DOI: 10.7270/Q29W0D5K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF11 [1-973] (Homo sapiens (Human)) | BDBM115177 ((−)-Ethyl 2-[2-(2-benzoyl-5,6-dibromo-1H-ben...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.72E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Santiago de Compostela, Jenaro de la Fuente s/n, Campus Vida, Santiago de Compostela 15782 (Spain) | Assay Description The IC50 measurements were done using a microtubule-activated ATPase kinetic assay according to the manufacturer's instructions. Reactions were ... | Chembiochem 15: 1471-80 (2014) Article DOI: 10.1002/cbic.201402089 BindingDB Entry DOI: 10.7270/Q29W0D5K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF11 [1-973] (Homo sapiens (Human)) | BDBM23772 ((2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoi...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | MMDB PDB Article PubMed | n/a | n/a | 1.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Santiago de Compostela, Jenaro de la Fuente s/n, Campus Vida, Santiago de Compostela 15782 (Spain) | Assay Description The IC50 measurements were done using a microtubule-activated ATPase kinetic assay according to the manufacturer's instructions. Reactions were ... | Chembiochem 15: 1471-80 (2014) Article DOI: 10.1002/cbic.201402089 BindingDB Entry DOI: 10.7270/Q29W0D5K | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Kinesin-like protein KIF11 [1-973] (Homo sapiens (Human)) | BDBM115167 (Ethyl 2-[2-(2-benzyl-5,6-dibromo-1H-benzo[d]imidaz...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.29E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Santiago de Compostela, Jenaro de la Fuente s/n, Campus Vida, Santiago de Compostela 15782 (Spain) | Assay Description The IC50 measurements were done using a microtubule-activated ATPase kinetic assay according to the manufacturer's instructions. Reactions were ... | Chembiochem 15: 1471-80 (2014) Article DOI: 10.1002/cbic.201402089 BindingDB Entry DOI: 10.7270/Q29W0D5K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF11 [1-973] (Homo sapiens (Human)) | BDBM115175 ((−)-Ethyl 2-[2-(2-benzoyl-5,6-dibromo-1H-ben...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Santiago de Compostela, Jenaro de la Fuente s/n, Campus Vida, Santiago de Compostela 15782 (Spain) | Assay Description The IC50 measurements were done using a microtubule-activated ATPase kinetic assay according to the manufacturer's instructions. Reactions were ... | Chembiochem 15: 1471-80 (2014) Article DOI: 10.1002/cbic.201402089 BindingDB Entry DOI: 10.7270/Q29W0D5K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kinesin-like protein KIF11 [1-973] (Homo sapiens (Human)) | BDBM115179 (Monastrol | ethyl 4-(3-hydroxyphenyl)-6-methyl-2-s...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Santiago de Compostela, Jenaro de la Fuente s/n, Campus Vida, Santiago de Compostela 15782 (Spain) | Assay Description The IC50 measurements were done using a microtubule-activated ATPase kinetic assay according to the manufacturer's instructions. Reactions were ... | Chembiochem 15: 1471-80 (2014) Article DOI: 10.1002/cbic.201402089 BindingDB Entry DOI: 10.7270/Q29W0D5K | |||||||||||
More data for this Ligand-Target Pair |