Compile Data Set for Download or QSAR

Found 139 hits of ki for UniProtKB: P09238   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stromelysin-2 (Homo sapiens (Human))	BDBM50259948 (CHEMBL4096462) Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](CC(=O)NO)Cc1cc(no1)-c1ccc(cc1)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C30H32ClN5O10/c31-20-3-1-2-18(12-20)16-4-6-17(7-5-16)24-15-21(46-36-24)13-19(14-25(37)35-45)29(43)34-23(9-11-27(40)41)30(44)33-22(28(32)42)8-10-26(38)39/h1-7,12,15,19,22-23,45H,8-11,13-14H2,(H2,32,42)(H,33,44)(H,34,43)(H,35,37)(H,38,39)(H,40,41)/t19-,22+,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of human MMP10 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate by spectrophotometric analysis				J Med Chem 60: 403-414 (2017) Article DOI: 10.1021/acs.jmedchem.6b01420 BindingDB Entry DOI: 10.7270/Q24X5B7B
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120222 (US8691753, 71) Show SMILES OC(=O)CC[C@H](NC(=O)CCc1ccc(cc1)-c1ccc(cc1)-c1ccccc1)C(=O)Nc1cccc(CC(O)=O)c1 |r| Show InChI InChI=1S/C34H32N2O6/c37-31(36-30(18-20-32(38)39)34(42)35-29-8-4-5-24(21-29)22-33(40)41)19-11-23-9-12-26(13-10-23)28-16-14-27(15-17-28)25-6-2-1-3-7-25/h1-10,12-17,21,30H,11,18-20,22H2,(H,35,42)(H,36,37)(H,38,39)(H,40,41)/t30-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM92441 (RXP470, 1 | RXP470, Compound 4) Show SMILES NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)C(Cc1cc(no1)-c1ccc(cc1)-c1cccc(Cl)c1)CP(O)(=O)c1ccc(Br)cc1 |r| Show InChI InChI=1S/C35H35BrClN4O10P/c36-24-8-10-27(11-9-24)52(49,50)19-23(34(47)40-29(13-15-32(44)45)35(48)39-28(33(38)46)12-14-31(42)43)17-26-18-30(41-51-26)21-6-4-20(5-7-21)22-2-1-3-25(37)16-22/h1-11,16,18,23,28-29H,12-15,17,19H2,(H2,38,46)(H,39,48)(H,40,47)(H,42,43)(H,44,45)(H,49,50)/t23?,28-,29+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	8	-11.0	n/a	n/a	n/a	n/a	n/a	6.8	25
Commissariat á l'Energie Atomique					Assay Description Enzyme assay using human matrix metalloproteases or ADAMTS.				J Biol Chem 287: 26647-56 (2012) Article DOI: 10.1074/jbc.M112.380782 BindingDB Entry DOI: 10.7270/Q2H993SB
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM92441 (RXP470, 1 | RXP470, Compound 4) Show SMILES NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)C(Cc1cc(no1)-c1ccc(cc1)-c1cccc(Cl)c1)CP(O)(=O)c1ccc(Br)cc1 |r| Show InChI InChI=1S/C35H35BrClN4O10P/c36-24-8-10-27(11-9-24)52(49,50)19-23(34(47)40-29(13-15-32(44)45)35(48)39-28(33(38)46)12-14-31(42)43)17-26-18-30(41-51-26)21-6-4-20(5-7-21)22-2-1-3-25(37)16-22/h1-11,16,18,23,28-29H,12-15,17,19H2,(H2,38,46)(H,39,48)(H,40,47)(H,42,43)(H,44,45)(H,49,50)/t23?,28-,29+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	8.30	-11.0	n/a	n/a	n/a	n/a	n/a	6.8	25
Commissariat à l'Energie Atomique					Assay Description Enzyme assay using matrix metalloproteinases.				J Biol Chem 285: 35900-9 (2010) Article DOI: 10.1074/jbc.M110.139634 BindingDB Entry DOI: 10.7270/Q25X27HV
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120215 (US8691753, 64) Show SMILES NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C30H31N3O7/c31-29(39)25(18-28(37)38)33-30(40)24(15-17-27(35)36)32-26(34)16-8-19-6-9-21(10-7-19)23-13-11-22(12-14-23)20-4-2-1-3-5-20/h1-7,9-14,24-25H,8,15-18H2,(H2,31,39)(H,32,34)(H,33,40)(H,35,36)(H,37,38)/t24-,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120160 (US8691753, 8) Show SMILES NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1cc(no1)-c1ccc(cc1)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C27H27ClN4O8/c28-18-3-1-2-17(12-18)15-4-6-16(7-5-15)21-13-19(40-32-21)8-10-23(33)30-20(9-11-24(34)35)27(39)31-22(26(29)38)14-25(36)37/h1-7,12-13,20,22H,8-11,14H2,(H2,29,38)(H,30,33)(H,31,39)(H,34,35)(H,36,37)/t20-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120244 (US8691753, 93) Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ccc(s1)-c1nc2ccccc2s1 |r| Show InChI InChI=1S/C30H30N4O7S2/c31-28(40)20(10-15-26(36)37)33-29(41)21(11-16-27(38)39)32-25(35)14-7-17-5-8-18(9-6-17)22-12-13-24(42-22)30-34-19-3-1-2-4-23(19)43-30/h1-6,8-9,12-13,20-21H,7,10-11,14-16H2,(H2,31,40)(H,32,35)(H,33,41)(H,36,37)(H,38,39)/t20-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	38.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120157 (US8691753, 5) Show SMILES NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1cc(no1)-c1ccc(cc1)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C28H29ClN4O8/c29-19-3-1-2-18(14-19)16-4-6-17(7-5-16)23-15-20(41-33-23)8-11-24(34)31-22(10-13-26(37)38)28(40)32-21(27(30)39)9-12-25(35)36/h1-7,14-15,21-22H,8-13H2,(H2,30,39)(H,31,34)(H,32,40)(H,35,36)(H,37,38)/t21-,22+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120155 (US8691753, 3) Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1cc(no1)-c1ccc(cc1)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C28H29ClN4O8/c29-19-3-1-2-18(14-19)16-4-6-17(7-5-16)23-15-20(41-33-23)8-11-24(34)31-22(10-13-26(37)38)28(40)32-21(27(30)39)9-12-25(35)36/h1-7,14-15,21-22H,8-13H2,(H2,30,39)(H,31,34)(H,32,40)(H,35,36)(H,37,38)/t21-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	US Patent	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120158 (US8691753, 6) Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)CCc1cc(no1)-c1ccc(cc1)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C28H29ClN4O8/c29-19-3-1-2-18(14-19)16-4-6-17(7-5-16)23-15-20(41-33-23)8-11-24(34)31-22(10-13-26(37)38)28(40)32-21(27(30)39)9-12-25(35)36/h1-7,14-15,21-22H,8-13H2,(H2,30,39)(H,31,34)(H,32,40)(H,35,36)(H,37,38)/t21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01855 BindingDB Entry DOI: 10.7270/Q2GB281X
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120164 (US8691753, 12) Show SMILES NC(=O)[C@H](CCCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1cc(no1)-c1ccc(cc1)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C29H31ClN4O8/c30-20-4-1-3-19(15-20)17-7-9-18(10-8-17)24-16-21(42-34-24)11-13-25(35)32-23(12-14-27(38)39)29(41)33-22(28(31)40)5-2-6-26(36)37/h1,3-4,7-10,15-16,22-23H,2,5-6,11-14H2,(H2,31,40)(H,32,35)(H,33,41)(H,36,37)(H,38,39)/t22-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM92448 (Inhibitor, 18) Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C26H26N2O4/c27-26(32)23(15-17-25(30)31)28-24(29)16-8-18-6-9-20(10-7-18)22-13-11-21(12-14-22)19-4-2-1-3-5-19/h1-7,9-14,23H,8,15-17H2,(H2,27,32)(H,28,29)(H,30,31)/t23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	54	-9.91	n/a	n/a	n/a	n/a	n/a	6.8	25
Commissariat á l'Energie Atomique					Assay Description Enzyme assay using human matrix metalloproteases or ADAMTS.				J Biol Chem 287: 26647-56 (2012) Article DOI: 10.1074/jbc.M112.380782 BindingDB Entry DOI: 10.7270/Q2H993SB
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120219 (US8691753, 68) Show SMILES NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C29H31N3O6/c30-28(37)25(18-33)32-29(38)24(15-17-27(35)36)31-26(34)16-8-19-6-9-21(10-7-19)23-13-11-22(12-14-23)20-4-2-1-3-5-20/h1-7,9-14,24-25,33H,8,15-18H2,(H2,30,37)(H,31,34)(H,32,38)(H,35,36)/t24-,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120212 (US8691753, 61 | US8691753, 72) Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C31H33N3O7/c32-30(40)25(15-18-28(36)37)34-31(41)26(16-19-29(38)39)33-27(35)17-8-20-6-9-22(10-7-20)24-13-11-23(12-14-24)21-4-2-1-3-5-21/h1-7,9-14,25-26H,8,15-19H2,(H2,32,40)(H,33,35)(H,34,41)(H,36,37)(H,38,39)/t25-,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120258 (US8691753, 95 bis) Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](CC(O)=O)Cc1ccc(cc1)-c1cc(cs1)-c1ccccc1 |r| Show InChI InChI=1S/C31H33N3O9S/c32-29(41)23(10-12-26(35)36)33-31(43)24(11-13-27(37)38)34-30(42)21(16-28(39)40)14-18-6-8-20(9-7-18)25-15-22(17-44-25)19-4-2-1-3-5-19/h1-9,15,17,21,23-24H,10-14,16H2,(H2,32,41)(H,33,43)(H,34,42)(H,35,36)(H,37,38)(H,39,40)/t21-,23+,24+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120162 (US8691753, 10) Show SMILES NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)CCc1cc(no1)-c1ccc(cc1)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C26H25ClN4O8/c27-17-3-1-2-16(10-17)14-4-6-15(7-5-14)19-11-18(39-31-19)8-9-22(32)29-21(13-24(35)36)26(38)30-20(25(28)37)12-23(33)34/h1-7,10-11,20-21H,8-9,12-13H2,(H2,28,37)(H,29,32)(H,30,38)(H,33,34)(H,35,36)/t20-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	93	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120191 (US8691753, 39) Show SMILES CC[C@H](NC(=O)CCc1ccc(cc1)-c1nc2ccccc2s1)C(=O)N[C@@H](CCC(O)=O)C(N)=O |r| Show InChI InChI=1S/C25H28N4O5S/c1-2-17(24(34)28-19(23(26)33)12-14-22(31)32)27-21(30)13-9-15-7-10-16(11-8-15)25-29-18-5-3-4-6-20(18)35-25/h3-8,10-11,17,19H,2,9,12-14H2,1H3,(H2,26,33)(H,27,30)(H,28,34)(H,31,32)/t17-,19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120213 (US8691753, 62) Show SMILES NC(=O)CC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ccc(cc1)-c1ccccc1)C(N)=O |r| Show InChI InChI=1S/C31H34N4O6/c32-27(36)17-15-25(30(33)40)35-31(41)26(16-19-29(38)39)34-28(37)18-8-20-6-9-22(10-7-20)24-13-11-23(12-14-24)21-4-2-1-3-5-21/h1-7,9-14,25-26H,8,15-19H2,(H2,32,36)(H2,33,40)(H,34,37)(H,35,41)(H,38,39)/t25-,26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120159 (US8691753, 7) Show SMILES NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)CCc1cc(no1)-c1ccc(cc1)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C28H29ClN4O8/c29-19-3-1-2-18(14-19)16-4-6-17(7-5-16)23-15-20(41-33-23)8-11-24(34)31-22(10-13-26(37)38)28(40)32-21(27(30)39)9-12-25(35)36/h1-7,14-15,21-22H,8-13H2,(H2,30,39)(H,31,34)(H,32,40)(H,35,36)(H,37,38)/t21-,22-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	111	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120168 (US8691753, 16) Show SMILES CC[C@H](NC(=O)CCc1cc(no1)-c1ccc(cc1)-c1ccccc1)C(=O)N[C@@H](CCC(O)=O)C(N)=O |r| Show InChI InChI=1S/C27H30N4O6/c1-2-21(27(36)30-22(26(28)35)13-15-25(33)34)29-24(32)14-12-20-16-23(31-37-20)19-10-8-18(9-11-19)17-6-4-3-5-7-17/h3-11,16,21-22H,2,12-15H2,1H3,(H2,28,35)(H,29,32)(H,30,36)(H,33,34)/t21-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	114	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120216 (US8691753, 65) Show SMILES NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C35H35N3O6/c36-34(43)31(22-24-8-17-29(39)18-9-24)38-35(44)30(19-21-33(41)42)37-32(40)20-10-23-6-11-26(12-7-23)28-15-13-27(14-16-28)25-4-2-1-3-5-25/h1-9,11-18,30-31,39H,10,19-22H2,(H2,36,43)(H,37,40)(H,38,44)(H,41,42)/t30-,31-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	119	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120156 (US8691753, 4) Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1cc(no1)-c1ccc(cc1)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C23H22ClN3O5/c24-17-3-1-2-16(12-17)14-4-6-15(7-5-14)20-13-18(32-27-20)8-10-21(28)26-19(23(25)31)9-11-22(29)30/h1-7,12-13,19H,8-11H2,(H2,25,31)(H,26,28)(H,29,30)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	122	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120217 (US8691753, 66) Show SMILES C[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ccc(cc1)-c1ccccc1)C(N)=O |r| Show InChI InChI=1S/C29H31N3O5/c1-19(28(30)36)31-29(37)25(16-18-27(34)35)32-26(33)17-9-20-7-10-22(11-8-20)24-14-12-23(13-15-24)21-5-3-2-4-6-21/h2-8,10-15,19,25H,9,16-18H2,1H3,(H2,30,36)(H,31,37)(H,32,33)(H,34,35)/t19-,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120241 (US8691753, 90) Show SMILES OC(=O)CC[C@H](NC(=O)CCc1ccc(cc1)-c1cccs1)C(=O)Nc1cccc(CC(O)=O)c1 |r| Show InChI InChI=1S/C26H26N2O6S/c29-23(12-8-17-6-9-19(10-7-17)22-5-2-14-35-22)28-21(11-13-24(30)31)26(34)27-20-4-1-3-18(15-20)16-25(32)33/h1-7,9-10,14-15,21H,8,11-13,16H2,(H,27,34)(H,28,29)(H,30,31)(H,32,33)/t21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	143	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50265078 ((4S)-5-amino-4-((2S)-2-((2S)-3-((4-bromophenyl)(hy...) Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1cc(no1)-c1ccc(cc1)-c1cccc(Cl)c1)CP(O)(=O)c1ccc(Br)cc1 |r| Show InChI InChI=1S/C35H35BrClN4O10P/c36-24-8-10-27(11-9-24)52(49,50)19-23(34(47)40-29(13-15-32(44)45)35(48)39-28(33(38)46)12-14-31(42)43)17-26-18-30(41-51-26)21-6-4-20(5-7-21)22-2-1-3-25(37)16-22/h1-11,16,18,23,28-29H,12-15,17,19H2,(H2,38,46)(H,39,48)(H,40,47)(H,42,43)(H,44,45)(H,49,50)/t23-,28+,29+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	149	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Paris-Saclay Curated by ChEMBL					Assay Description Inhibition of human MMP10 catalytic domain using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 fluorogenic substrate by spectrophotometric analysis				J Med Chem 60: 403-414 (2017) Article DOI: 10.1021/acs.jmedchem.6b01420 BindingDB Entry DOI: 10.7270/Q24X5B7B
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120243 (US8691753, 92) Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ccc(s1)-c1ccccc1 |r| Show InChI InChI=1S/C29H31N3O7S/c30-28(38)21(11-16-26(34)35)32-29(39)22(12-17-27(36)37)31-25(33)15-8-18-6-9-20(10-7-18)24-14-13-23(40-24)19-4-2-1-3-5-19/h1-7,9-10,13-14,21-22H,8,11-12,15-17H2,(H2,30,38)(H,31,33)(H,32,39)(H,34,35)(H,36,37)/t21-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	156	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120218 (US8691753, 67) Show SMILES NC(=O)C(Cc1cnc[nH]1)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C32H33N5O5/c33-31(41)28(18-26-19-34-20-35-26)37-32(42)27(15-17-30(39)40)36-29(38)16-8-21-6-9-23(10-7-21)25-13-11-24(12-14-25)22-4-2-1-3-5-22/h1-7,9-14,19-20,27-28H,8,15-18H2,(H2,33,41)(H,34,35)(H,36,38)(H,37,42)(H,39,40)/t27-,28?/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	168	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50182403 ((2R,3S)-N1-((S)-1-(3-phenoxybenzyl)-2-oxoazepan-3-...) Show SMILES CCC[C@@H]([C@@H](CC(C)C)C(=O)N[C@H]1CCCCN(Cc2cccc(Oc3ccccc3)c2)C1=O)C(=O)NO Show InChI InChI=1S/C30H41N3O5/c1-4-11-25(29(35)32-37)26(18-21(2)3)28(34)31-27-16-8-9-17-33(30(27)36)20-22-12-10-15-24(19-22)38-23-13-6-5-7-14-23/h5-7,10,12-15,19,21,25-27,37H,4,8-9,11,16-18,20H2,1-3H3,(H,31,34)(H,32,35)/t25-,26+,27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of MMP10				Bioorg Med Chem Lett 16: 2357-63 (2006) Article DOI: 10.1016/j.bmcl.2006.01.055 BindingDB Entry DOI: 10.7270/Q2WD405K
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120170 (US8691753, 18) Show SMILES CC[C@H](NC(=O)CCc1cc(no1)-c1ccc(cc1)-c1ccccc1)C(=O)N[C@@H](CC(O)=O)C(N)=O |r| Show InChI InChI=1S/C26H28N4O6/c1-2-20(26(35)29-22(25(27)34)15-24(32)33)28-23(31)13-12-19-14-21(30-36-19)18-10-8-17(9-11-18)16-6-4-3-5-7-16/h3-11,14,20,22H,2,12-13,15H2,1H3,(H2,27,34)(H,28,31)(H,29,35)(H,32,33)/t20-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	196	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50229322 ((3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)met...) Show SMILES Cc1cc(COc2ccc(cc2)C(=O)N[C@@H]2CN(CC#C)C[C@@H]2C(=O)NO)c2ccccc2n1 |r| Show InChI InChI=1S/C26H26N4O4/c1-3-12-30-14-22(26(32)29-33)24(15-30)28-25(31)18-8-10-20(11-9-18)34-16-19-13-17(2)27-23-7-5-4-6-21(19)23/h1,4-11,13,22,24,33H,12,14-16H2,2H3,(H,28,31)(H,29,32)/t22-,24+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Binding affinity to MMP10				Bioorg Med Chem Lett 18: 694-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.059 BindingDB Entry DOI: 10.7270/Q2BV7HGG
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120173 (US8691753, 21) Show SMILES NC(=O)CC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1cc(no1)-c1ccc(cc1)-c1ccccc1)C(N)=O |r| Show InChI InChI=1S/C28H31N5O7/c29-24(34)13-11-21(27(30)38)32-28(39)22(12-15-26(36)37)31-25(35)14-10-20-16-23(33-40-20)19-8-6-18(7-9-19)17-4-2-1-3-5-17/h1-9,16,21-22H,10-15H2,(H2,29,34)(H2,30,38)(H,31,35)(H,32,39)(H,36,37)/t21-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	256	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120175 (US8691753, 23) Show SMILES C[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1cc(no1)-c1ccc(cc1)-c1ccccc1)C(N)=O |r| Show InChI InChI=1S/C26H28N4O6/c1-16(25(27)34)28-26(35)21(12-14-24(32)33)29-23(31)13-11-20-15-22(30-36-20)19-9-7-18(8-10-19)17-5-3-2-4-6-17/h2-10,15-16,21H,11-14H2,1H3,(H2,27,34)(H,28,35)(H,29,31)(H,32,33)/t16-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	276	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM92446 (Inhibitor, 16) Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)c1ccc(cc1)-c1cc(cs1)-c1ccccc1 |r| Show InChI InChI=1S/C22H20N2O4S/c23-21(27)18(10-11-20(25)26)24-22(28)16-8-6-15(7-9-16)19-12-17(13-29-19)14-4-2-1-3-5-14/h1-9,12-13,18H,10-11H2,(H2,23,27)(H,24,28)(H,25,26)/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem	Article PubMed	299	-8.89	n/a	n/a	n/a	n/a	n/a	6.8	25
Commissariat á l'Energie Atomique					Assay Description Enzyme assay using human matrix metalloproteases or ADAMTS.				J Biol Chem 287: 26647-56 (2012) Article DOI: 10.1074/jbc.M112.380782 BindingDB Entry DOI: 10.7270/Q2H993SB
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120256 (US8691753, 106) Show SMILES OC(=O)CC[C@H](NC(=O)CCc1ccc(cc1)-c1cc(cs1)-c1ccccc1)C(=O)Nc1cccc(CC(O)=O)c1 |r| Show InChI InChI=1S/C32H30N2O6S/c35-29(34-27(14-16-30(36)37)32(40)33-26-8-4-5-22(17-26)18-31(38)39)15-11-21-9-12-24(13-10-21)28-19-25(20-41-28)23-6-2-1-3-7-23/h1-10,12-13,17,19-20,27H,11,14-16,18H2,(H,33,40)(H,34,35)(H,36,37)(H,38,39)/t27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	318	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50260826 (CHEMBL497761 | N-hydroxy-2,3-bis(4-methoxyphenylsu...) Show SMILES COc1ccc(cc1)S(=O)(=O)NCC(NS(=O)(=O)c1ccc(OC)cc1)C(=O)NO Show InChI InChI=1S/C17H21N3O8S2/c1-27-12-3-7-14(8-4-12)29(23,24)18-11-16(17(21)19-22)20-30(25,26)15-9-5-13(28-2)6-10-15/h3-10,16,18,20,22H,11H2,1-2H3,(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	335	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
North Dakota State University Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP10				Bioorg Med Chem Lett 18: 3333-7 (2008) Article DOI: 10.1016/j.bmcl.2008.04.035 BindingDB Entry DOI: 10.7270/Q2SX6D1R
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM92449 (Inhibitor, 19) Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ccc(s1)-c1ccccc1 |r| Show InChI InChI=1S/C24H24N2O4S/c25-24(30)19(11-15-23(28)29)26-22(27)14-8-16-6-9-18(10-7-16)21-13-12-20(31-21)17-4-2-1-3-5-17/h1-7,9-10,12-13,19H,8,11,14-15H2,(H2,25,30)(H,26,27)(H,28,29)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	352	-8.80	n/a	n/a	n/a	n/a	n/a	6.8	25
Commissariat á l'Energie Atomique					Assay Description Enzyme assay using human matrix metalloproteases or ADAMTS.				J Biol Chem 287: 26647-56 (2012) Article DOI: 10.1074/jbc.M112.380782 BindingDB Entry DOI: 10.7270/Q2H993SB
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120242 (US8691753, 91) Show SMILES Cc1ccc(s1)-c1ccc(CCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(N)=O)cc1 |r| Show InChI InChI=1S/C24H29N3O7S/c1-14-2-10-19(35-14)16-6-3-15(4-7-16)5-11-20(28)26-18(9-13-22(31)32)24(34)27-17(23(25)33)8-12-21(29)30/h2-4,6-7,10,17-18H,5,8-9,11-13H2,1H3,(H2,25,33)(H,26,28)(H,27,34)(H,29,30)(H,31,32)/t17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	353	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM50260802 (CHEMBL496717 | N-hydroxy-2,3-bis(phenylsulfonamido...) Show SMILES ONC(=O)C(CNS(=O)(=O)c1ccccc1)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C15H17N3O6S2/c19-15(17-20)14(18-26(23,24)13-9-5-2-6-10-13)11-16-25(21,22)12-7-3-1-4-8-12/h1-10,14,16,18,20H,11H2,(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	356	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
North Dakota State University Curated by ChEMBL					Assay Description Inhibition of human recombinant MMP10				Bioorg Med Chem Lett 18: 3333-7 (2008) Article DOI: 10.1016/j.bmcl.2008.04.035 BindingDB Entry DOI: 10.7270/Q2SX6D1R
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120231 (US8691753, 80) Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1cccs1 |r| Show InChI InChI=1S/C23H27N3O7S/c24-22(32)16(8-11-20(28)29)26-23(33)17(9-12-21(30)31)25-19(27)10-5-14-3-6-15(7-4-14)18-2-1-13-34-18/h1-4,6-7,13,16-17H,5,8-12H2,(H2,24,32)(H,25,27)(H,26,33)(H,28,29)(H,30,31)/t16-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	373	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120220 (US8691753, 69) Show SMILES CC(C)C[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ccc(cc1)-c1ccccc1)C(N)=O |r| Show InChI InChI=1S/C32H37N3O5/c1-21(2)20-28(31(33)39)35-32(40)27(17-19-30(37)38)34-29(36)18-10-22-8-11-24(12-9-22)26-15-13-25(14-16-26)23-6-4-3-5-7-23/h3-9,11-16,21,27-28H,10,17-20H2,1-2H3,(H2,33,39)(H,34,36)(H,35,40)(H,37,38)/t27-,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	382	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM92447 (Inhibitor, 17) Show SMILES Cc1ccc(s1)-c1ccc(CCC(=O)N[C@@H](CCC(O)=O)C(N)=O)cc1 |r| Show InChI InChI=1S/C19H22N2O4S/c1-12-2-9-16(26-12)14-6-3-13(4-7-14)5-10-17(22)21-15(19(20)25)8-11-18(23)24/h2-4,6-7,9,15H,5,8,10-11H2,1H3,(H2,20,25)(H,21,22)(H,23,24)/t15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	390	-8.74	n/a	n/a	n/a	n/a	n/a	6.8	25
Commissariat á l'Energie Atomique					Assay Description Enzyme assay using human matrix metalloproteases or ADAMTS.				J Biol Chem 287: 26647-56 (2012) Article DOI: 10.1074/jbc.M112.380782 BindingDB Entry DOI: 10.7270/Q2H993SB
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120221 (US8691753, 70) Show SMILES OC(=O)CC[C@H](NC(=O)CCc1ccc(cc1)-c1ccc(cc1)-c1ccccc1)C(=O)N1CCCC(CC(O)=O)C1 |r| Show InChI InChI=1S/C33H36N2O6/c36-30(34-29(17-19-31(37)38)33(41)35-20-4-5-24(22-35)21-32(39)40)18-10-23-8-11-26(12-9-23)28-15-13-27(14-16-28)25-6-2-1-3-7-25/h1-3,6-9,11-16,24,29H,4-5,10,17-22H2,(H,34,36)(H,37,38)(H,39,40)/t24?,29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	421	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120225 (US8691753, 74) Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)CCc1ccc(cc1)-c1ccc(cc1)-c1ccccc1 |r| Show InChI InChI=1S/C30H31N3O7/c31-29(39)24(15-17-27(35)36)33-30(40)25(18-28(37)38)32-26(34)16-8-19-6-9-21(10-7-19)23-13-11-22(12-14-23)20-4-2-1-3-5-20/h1-7,9-14,24-25H,8,15-18H2,(H2,31,39)(H,32,34)(H,33,40)(H,35,36)(H,37,38)/t24-,25-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120203 (US8691753, 52) Show SMILES OC(=O)CC[C@H](NC(=O)CCc1ccc(cc1)-c1ccccc1)C(=O)Nc1cccc(CC(O)=O)c1 |r| Show InChI InChI=1S/C28H28N2O6/c31-25(15-11-19-9-12-22(13-10-19)21-6-2-1-3-7-21)30-24(14-16-26(32)33)28(36)29-23-8-4-5-20(17-23)18-27(34)35/h1-10,12-13,17,24H,11,14-16,18H2,(H,29,36)(H,30,31)(H,32,33)(H,34,35)/t24-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	433	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120234 (US8691753, 83) Show SMILES NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1cccs1 |r| Show InChI InChI=1S/C22H25N3O7S/c23-21(31)16(12-20(29)30)25-22(32)15(8-10-19(27)28)24-18(26)9-5-13-3-6-14(7-4-13)17-2-1-11-33-17/h1-4,6-7,11,15-16H,5,8-10,12H2,(H2,23,31)(H,24,26)(H,25,32)(H,27,28)(H,29,30)/t15-,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	435	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120190 (US8691753, 38) Show SMILES CC[C@H](NC(=O)CCc1ccc(cc1)-c1ccsc1)C(=O)N[C@@H](CCC(O)=O)C(N)=O |r| Show InChI InChI=1S/C22H27N3O5S/c1-2-17(22(30)25-18(21(23)29)8-10-20(27)28)24-19(26)9-5-14-3-6-15(7-4-14)16-11-12-31-13-16/h3-4,6-7,11-13,17-18H,2,5,8-10H2,1H3,(H2,23,29)(H,24,26)(H,25,30)(H,27,28)/t17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	446	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120214 (US8691753, 63) Show SMILES NCCCC[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1ccc(cc1)-c1ccccc1)C(N)=O |r| Show InChI InChI=1S/C32H38N4O5/c33-21-5-4-8-27(31(34)40)36-32(41)28(18-20-30(38)39)35-29(37)19-11-22-9-12-24(13-10-22)26-16-14-25(15-17-26)23-6-2-1-3-7-23/h1-3,6-7,9-10,12-17,27-28H,4-5,8,11,18-21,33H2,(H2,34,40)(H,35,37)(H,36,41)(H,38,39)/t27-,28-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	447	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120158 (US8691753, 6) Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)CCc1cc(no1)-c1ccc(cc1)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C28H29ClN4O8/c29-19-3-1-2-18(14-19)16-4-6-17(7-5-16)23-15-20(41-33-23)8-11-24(34)31-22(10-13-26(37)38)28(40)32-21(27(30)39)9-12-25(35)36/h1-7,14-15,21-22H,8-13H2,(H2,30,39)(H,31,34)(H,32,40)(H,35,36)(H,37,38)/t21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	489	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120235 (US8691753, 84) Show SMILES NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(O)=O)NC(=O)CCc1ccc(cc1)-c1cccs1 |r| Show InChI InChI=1S/C27H29N3O6S/c28-26(35)22(16-18-5-10-20(31)11-6-18)30-27(36)21(12-14-25(33)34)29-24(32)13-7-17-3-8-19(9-4-17)23-2-1-15-37-23/h1-6,8-11,15,21-22,31H,7,12-14,16H2,(H2,28,35)(H,29,32)(H,30,36)(H,33,34)/t21-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	514	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair
Stromelysin-2 (Homo sapiens (Human))	BDBM120161 (US8691753, 9) Show SMILES NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)CCc1cc(no1)-c1ccc(cc1)-c1cccc(Cl)c1 |r| Show InChI InChI=1S/C27H27ClN4O8/c28-18-3-1-2-17(12-18)15-4-6-16(7-5-15)21-13-19(40-32-21)8-10-23(33)30-22(14-25(36)37)27(39)31-20(26(29)38)9-11-24(34)35/h1-7,12-13,20,22H,8-11,14H2,(H2,29,38)(H,30,33)(H,31,39)(H,34,35)(H,36,37)/t20-,22-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Commissariat A l'Energie Atomique et Aux Energies Alternatives US Patent					Assay Description The inhibition tests and the evaluation of the inhibition constants (Ki) on the various MMPs were carried out as described by Devel et al. (Devel et ...				US Patent US8691753 (2014) BindingDB Entry DOI: 10.7270/Q28P5Z5Q
					More data for this Ligand-Target Pair

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