Compile Data Set for Download or QSAR

Found 254 hits of ic50 data for polymerid = 6408   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interleukin-2 (Homo sapiens (Human))	BDBM128384 (US8802721, 1) Show SMILES Fc1cccc(F)c1NC(=O)c1ccc(s1)-c1cc(ccc1Cl)C(F)(F)F Show InChI InChI=1S/C18H9ClF5NOS/c19-11-5-4-9(18(22,23)24)8-10(11)14-6-7-15(27-14)17(26)25-16-12(20)2-1-3-13(16)21/h1-8H,(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Synta Pharmaceuticals Corp. US Patent					Assay Description Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...				US Patent US8802721 (2014) BindingDB Entry DOI: 10.7270/Q2CN72M4
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM128386 (US8802721, 3) Show SMILES COC(=O)c1ccc(C)c(c1)-c1ccc(s1)C(=O)Nc1c(F)cccc1F Show InChI InChI=1S/C20H15F2NO3S/c1-11-6-7-12(20(25)26-2)10-13(11)16-8-9-17(27-16)19(24)23-18-14(21)4-3-5-15(18)22/h3-10H,1-2H3,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.40	n/a	n/a	n/a	n/a	n/a	n/a
Synta Pharmaceuticals Corp. US Patent					Assay Description Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...				US Patent US8802721 (2014) BindingDB Entry DOI: 10.7270/Q2CN72M4
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412467 (N-(5-(5-ethyl-2-(5-methylisoxazol-3- yl)thiazol-4-...) Show SMILES CCc1sc(nc1-c1ccc(NC(=O)c2cncc(C)c2C)nc1)-c1cc(C)on1 Show InChI InChI=1S/C22H21N5O2S/c1-5-18-20(26-22(30-18)17-8-13(3)29-27-17)15-6-7-19(24-10-15)25-21(28)16-11-23-9-12(2)14(16)4/h6-11H,5H2,1-4H3,(H,24,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM50575333 (CHEMBL4857063) Show SMILES Fc1cccc(F)c1C(=O)Nc1ccc(cc1)-c1cc(ccc1Cl)C(F)(F)F Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01403 BindingDB Entry DOI: 10.7270/Q2C82F4Q
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412475 (5-ethyl-N-(5-(5-ethyl-2-(5- methylisoxazol-3-yl)th...) Show SMILES CCc1sc(nc1-c1ccc(NC(=O)c2cncc(CC)c2C)nc1)-c1cc(C)on1 Show InChI InChI=1S/C23H23N5O2S/c1-5-15-10-24-12-17(14(15)4)22(29)26-20-8-7-16(11-25-20)21-19(6-2)31-23(27-21)18-9-13(3)30-28-18/h7-12H,5-6H2,1-4H3,(H,25,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412392 (5-fluoro-4-methyl-N-(5-(5-(1-methyl- 1H-pyrazol-4-...) Show SMILES Cc1c(F)cncc1C(=O)Nc1cnc(cn1)-c1cc(ccc1OC(F)(F)F)-c1cnn(C)c1 Show InChI InChI=1S/C22H16F4N6O2/c1-12-16(7-27-8-17(12)23)21(33)31-20-10-28-18(9-29-20)15-5-13(14-6-30-32(2)11-14)3-4-19(15)34-22(24,25)26/h3-11H,1-2H3,(H,29,31,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412445 (N-(5-(2-chloro-5- cyclopropoxyphenyl)pyridin-2-yl)...) Show SMILES Cc1ccncc1C(=O)Nc1ccc(cn1)-c1cc(OC2CC2)ccc1Cl Show InChI InChI=1S/C21H18ClN3O2/c1-13-8-9-23-12-18(13)21(26)25-20-7-2-14(11-24-20)17-10-16(5-6-19(17)22)27-15-3-4-15/h2,5-12,15H,3-4H2,1H3,(H,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412443 (5-bromo-N-(5-(5-ethyl-2-(5- methylisoxazol-3-yl)th...) Show SMILES CCc1sc(nc1-c1ccc(NC(=O)c2cncc(Br)c2C)nc1)-c1cc(C)on1 Show InChI InChI=1S/C21H18BrN5O2S/c1-4-17-19(26-21(30-17)16-7-11(2)29-27-16)13-5-6-18(24-8-13)25-20(28)14-9-23-10-15(22)12(14)3/h5-10H,4H2,1-3H3,(H,24,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412441 (N-(5-(2-chloro-5- cyclopropoxyphenyl)pyridin-2-yl)...) Show SMILES Cc1c(F)cncc1C(=O)Nc1ccc(cn1)-c1cc(OC2CC2)ccc1Cl Show InChI InChI=1S/C21H17ClFN3O2/c1-12-17(10-24-11-19(12)23)21(27)26-20-7-2-13(9-25-20)16-8-15(5-6-18(16)22)28-14-3-4-14/h2,5-11,14H,3-4H2,1H3,(H,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412442 (5-chloro-N-(5-(5-ethyl-2-(5- methylisoxazol-3-yl)t...) Show SMILES CCc1sc(nc1-c1ccc(NC(=O)c2cncc(Cl)c2C)nc1)-c1cc(C)on1 Show InChI InChI=1S/C21H18ClN5O2S/c1-4-17-19(26-21(30-17)16-7-11(2)29-27-16)13-5-6-18(24-8-13)25-20(28)14-9-23-10-15(22)12(14)3/h5-10H,4H2,1-3H3,(H,24,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM50587599 (CHEMBL5087453 | US11661419, Example 53 | US2023028...) Show SMILES [H][C@]12Cc3c(C[C@@]1(C)C2(F)F)[nH]nc3-c1nc2cc(N(C)C(=O)[C@H](C)N3CCOCC3)c(C)cc2[nH]1 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412479 (N-(5-(5-ethyl-2-(isoxazol-3- yl)thiazol-4-yl)pyrid...) Show SMILES CCc1sc(nc1-c1ccc(NC(=O)c2cncc(F)c2C)nc1)-c1ccon1 Show InChI InChI=1S/C20H16FN5O2S/c1-3-16-18(25-20(29-16)15-6-7-28-26-15)12-4-5-17(23-8-12)24-19(27)13-9-22-10-14(21)11(13)2/h4-10H,3H2,1-2H3,(H,23,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412489 (N-(5-(2-chloro-5-(1-methyl-1H- pyrazol-4-yl)phenyl...) Show SMILES Cc1c(cncc1C(=O)Nc1ccc(cn1)-c1cc(ccc1Cl)-c1cnn(C)c1)C#N Show InChI InChI=1S/C23H17ClN6O/c1-14-17(8-25)9-26-12-20(14)23(31)29-22-6-4-16(10-27-22)19-7-15(3-5-21(19)24)18-11-28-30(2)13-18/h3-7,9-13H,1-2H3,(H,27,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412476 (N-(5-(5-ethyl-2-(3-methylisoxazol-5- yl)thiazol-4-...) Show SMILES CCc1sc(nc1-c1ccc(NC(=O)c2cncc(F)c2C)nc1)-c1cc(C)no1 Show InChI InChI=1S/C21H18FN5O2S/c1-4-17-19(26-21(30-17)16-7-11(2)27-29-16)13-5-6-18(24-8-13)25-20(28)14-9-23-10-15(22)12(14)3/h5-10H,4H2,1-3H3,(H,24,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412440 (N-(5-(5-ethyl-2-(5-methylisoxazol-3- yl)thiazol-4-...) Show SMILES CCc1sc(nc1-c1ccc(NC(=O)c2cncc(F)c2C)nc1)-c1cc(C)on1 Show InChI InChI=1S/C21H18FN5O2S/c1-4-17-19(26-21(30-17)16-7-11(2)29-27-16)13-5-6-18(24-8-13)25-20(28)14-9-23-10-15(22)12(14)3/h5-10H,4H2,1-3H3,(H,24,25,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412447 (N-(5-(5-ethyl-2-(5-methylisoxazol-3- yl)thiazol-4-...) Show SMILES CCc1sc(nc1-c1ccc(NC(=O)c2cnccc2C)nc1)-c1cc(C)on1 Show InChI InChI=1S/C21H19N5O2S/c1-4-17-19(25-21(29-17)16-9-13(3)28-26-16)14-5-6-18(23-10-14)24-20(27)15-11-22-8-7-12(15)2/h5-11H,4H2,1-3H3,(H,23,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412451 (5-bromo-N-(5-(2-chloro-5- cyclopropoxyphenyl)pyraz...) Show SMILES Cc1c(Br)cncc1C(=O)Nc1cnc(cn1)-c1cc(OC2CC2)ccc1Cl Show InChI InChI=1S/C20H16BrClN4O2/c1-11-15(7-23-8-16(11)21)20(27)26-19-10-24-18(9-25-19)14-6-13(4-5-17(14)22)28-12-2-3-12/h4-10,12H,2-3H2,1H3,(H,25,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM50575331 (CHEMBL4868242) Show SMILES Cc1c(cccc1-c1ccc(NC(=O)c2c(F)cccc2F)cc1)-c1nn(C)c(=O)o1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01403 BindingDB Entry DOI: 10.7270/Q2C82F4Q
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412481 (5-chloro-N-(5-(2-chloro-5-(1-methyl- 1H-pyrazol-4-...) Show SMILES Cc1c(Cl)cncc1C(=O)Nc1cnc(cn1)-c1cc(ccc1Cl)-c1cnn(C)c1 Show InChI InChI=1S/C21H16Cl2N6O/c1-12-16(7-24-8-18(12)23)21(30)28-20-10-25-19(9-26-20)15-5-13(3-4-17(15)22)14-6-27-29(2)11-14/h3-11H,1-2H3,(H,26,28,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412488 (5-bromo-N-(5-(2-chloro-5-(1-methyl- 1H-pyrazol-4-y...) Show SMILES Cc1c(Br)cncc1C(=O)Nc1cnc(cn1)-c1cc(ccc1Cl)-c1cnn(C)c1 Show InChI InChI=1S/C21H16BrClN6O/c1-12-16(7-24-8-17(12)22)21(30)28-20-10-25-19(9-26-20)15-5-13(3-4-18(15)23)14-6-27-29(2)11-14/h3-11H,1-2H3,(H,26,28,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412468 (5-fluoro-4-methyl-N-(5-(5-methyl-2- (5-methylisoxa...) Show SMILES Cc1cc(no1)-c1nc(c(C)s1)-c1ccc(NC(=O)c2cncc(F)c2C)nc1 Show InChI InChI=1S/C20H16FN5O2S/c1-10-6-16(26-28-10)20-25-18(12(3)29-20)13-4-5-17(23-7-13)24-19(27)14-8-22-9-15(21)11(14)2/h4-9H,1-3H3,(H,23,24,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412377 (N-(5-(2-ethyl-5-(1-methyl-1H- pyrazol-4-yl)phenyl)...) Show SMILES CCc1ccc(cc1-c1ccc(NC(=O)c2cnccc2C)nc1)-c1cnn(C)c1 Show InChI InChI=1S/C24H23N5O/c1-4-17-5-6-18(20-13-27-29(3)15-20)11-21(17)19-7-8-23(26-12-19)28-24(30)22-14-25-10-9-16(22)2/h5-15H,4H2,1-3H3,(H,26,28,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412432 (N-(5-(2-chloro-5- cyclopropoxyphenyl)pyrazin-2-yl)...) Show SMILES Cc1ccncc1C(=O)Nc1cnc(cn1)-c1cc(OC2CC2)ccc1Cl Show InChI InChI=1S/C20H17ClN4O2/c1-12-6-7-22-9-16(12)20(26)25-19-11-23-18(10-24-19)15-8-14(4-5-17(15)21)27-13-2-3-13/h4-11,13H,2-3H2,1H3,(H,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412387 (N-(2'-chloro-5'-(trifluoromethyl)- [1,1'-biphenyl]...) Show SMILES Cc1ccncc1C(=O)Nc1ccc(cc1)-c1cc(ccc1Cl)C(F)(F)F Show InChI InChI=1S/C20H14ClF3N2O/c1-12-8-9-25-11-17(12)19(27)26-15-5-2-13(3-6-15)16-10-14(20(22,23)24)4-7-18(16)21/h2-11H,1H3,(H,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412384 (N-(5-(2-chloro-5-(5-methylthiazol-2- yl)phenyl)pyr...) Show SMILES Cc1cnc(s1)-c1ccc(Cl)c(c1)-c1cnc(NC(=O)c2cnccc2C)cn1 Show InChI InChI=1S/C21H16ClN5OS/c1-12-5-6-23-9-16(12)20(28)27-19-11-24-18(10-25-19)15-7-14(3-4-17(15)22)21-26-8-13(2)29-21/h3-11H,1-2H3,(H,25,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412446 (5-cyano-N-(5-(5-ethyl-2-(5- methylisoxazol-3-yl)th...) Show SMILES CCc1sc(nc1-c1ccc(NC(=O)c2cncc(C#N)c2C)nc1)-c1cc(C)on1 Show InChI InChI=1S/C22H18N6O2S/c1-4-18-20(27-22(31-18)17-7-12(2)30-28-17)14-5-6-19(25-10-14)26-21(29)16-11-24-9-15(8-23)13(16)3/h5-7,9-11H,4H2,1-3H3,(H,25,26,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM50587592 (CHEMBL5090091 | US11661419, Example 7 | US20230280...) Show SMILES [H][C@@]12C[C@]1(C)Cc1[nH]nc(-c3nc4cc(ccc4[nH]3)N(C)C(=O)[C@H](C)C3CCOCC3)c1C2 |r| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of IL-2 in CD3/CD28 activated human CD4+ve Th cells preincubated for 15 mins followed by addition of immuno-cult and measured after 24 hrs...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00619 BindingDB Entry DOI: 10.7270/Q2736VT6
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412511 (N-(5-(2-chloro-5- isopropoxyphenyl)pyrazin-2-yl)-4...) Show SMILES CC(C)Oc1ccc(Cl)c(c1)-c1cnc(NC(=O)c2cnccc2C)cn1 Show InChI InChI=1S/C20H19ClN4O2/c1-12(2)27-14-4-5-17(21)15(8-14)18-10-24-19(11-23-18)25-20(26)16-9-22-7-6-13(16)3/h4-12H,1-3H3,(H,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412459 (N-(5-(2-chloro-5- isopropoxyphenyl)pyridin-2-yl)-4...) Show SMILES CC(C)Oc1ccc(Cl)c(c1)-c1ccc(NC(=O)c2cnccc2C)nc1 Show InChI InChI=1S/C21H20ClN3O2/c1-13(2)27-16-5-6-19(22)17(10-16)15-4-7-20(24-11-15)25-21(26)18-12-23-9-8-14(18)3/h4-13H,1-3H3,(H,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM128385 (US8802721, 2) Show SMILES Cc1cnccc1NC(=O)c1ccc(s1)-c1cc(ccc1Cl)C(F)(F)F Show InChI InChI=1S/C18H12ClF3N2OS/c1-10-9-23-7-6-14(10)24-17(25)16-5-4-15(26-16)12-8-11(18(20,21)22)2-3-13(12)19/h2-9H,1H3,(H,23,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Synta Pharmaceuticals Corp. US Patent					Assay Description Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...				US Patent US8802721 (2014) BindingDB Entry DOI: 10.7270/Q2CN72M4
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412432 (N-(5-(2-chloro-5- cyclopropoxyphenyl)pyrazin-2-yl)...) Show SMILES Cc1ccncc1C(=O)Nc1cnc(cn1)-c1cc(OC2CC2)ccc1Cl Show InChI InChI=1S/C20H17ClN4O2/c1-12-6-7-22-9-16(12)20(26)25-19-11-23-18(10-24-19)15-8-14(4-5-17(15)21)27-13-2-3-13/h4-11,13H,2-3H2,1H3,(H,24,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM50575332 (CHEMBL4869725) Show SMILES Cc1c(cccc1-c1ccc(NC(=O)c2c(F)cccc2Cl)cc1)-c1nn(C)c(=O)o1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PHA-stimulated IL2 secretion in human Jurkat T cells preincubated for 10 mins followed by PHA addition and measured after 20 to 24 hrs ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01403 BindingDB Entry DOI: 10.7270/Q2C82F4Q
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412483 (5-bromo-N-(5-(2-chloro-5-(1-methyl- 1H-pyrazol-4-y...) Show SMILES Cc1c(Br)cncc1C(=O)Nc1ccc(cn1)-c1cc(ccc1Cl)-c1cnn(C)c1 Show InChI InChI=1S/C22H17BrClN5O/c1-13-18(10-25-11-19(13)23)22(30)28-21-6-4-15(8-26-21)17-7-14(3-5-20(17)24)16-9-27-29(2)12-16/h3-12H,1-2H3,(H,26,28,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412465 ((Z)-N-(5-(1-(4-bromophenyl)prop-1- en-1-yl)pyridin...) Show SMILES C\C=C(\c1ccc(Br)cc1)c1ccc(NC(=O)c2cncc(F)c2C)nc1 Show InChI InChI=1S/C21H17BrFN3O/c1-3-17(14-4-7-16(22)8-5-14)15-6-9-20(25-10-15)26-21(27)18-11-24-12-19(23)13(18)2/h3-12H,1-2H3,(H,25,26,27)/b17-3-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412482 (N-(5-(2-chloro-5-(1-methyl-1H- pyrazol-4-yl)phenyl...) Show SMILES Cc1c(F)cncc1C(=O)Nc1ccc(cn1)-c1cc(ccc1Cl)-c1cnn(C)c1 Show InChI InChI=1S/C22H17ClFN5O/c1-13-18(10-25-11-20(13)24)22(30)28-21-6-4-15(8-26-21)17-7-14(3-5-19(17)23)16-9-27-29(2)12-16/h3-12H,1-2H3,(H,26,28,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412472 ((Z)-5-fluoro-N-(5-(1-(4- methoxyphenyl)prop-1-en-1...) Show SMILES COc1ccc(cc1)C(=C\C)\c1ccc(NC(=O)c2cncc(F)c2C)nc1 Show InChI InChI=1S/C22H20FN3O2/c1-4-18(15-5-8-17(28-3)9-6-15)16-7-10-21(25-11-16)26-22(27)19-12-24-13-20(23)14(19)2/h4-13H,1-3H3,(H,25,26,27)/b18-4-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM128388 (US8802721, 117) Show SMILES Fc1cccc(F)c1C(=O)Nc1ccc(s1)-c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C18H10F5NOS/c19-12-5-2-6-13(20)16(12)17(25)24-15-8-7-14(26-15)10-3-1-4-11(9-10)18(21,22)23/h1-9H,(H,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16.5	n/a	n/a	n/a	n/a	n/a	n/a
Synta Pharmaceuticals Corp. US Patent					Assay Description Jurkat cells were placed in a 96 well plate (0.5 million cells per well in 1% FBS medium) then a test compound of this invention was added at differe...				US Patent US8802721 (2014) BindingDB Entry DOI: 10.7270/Q2CN72M4
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412504 (N-(5-(2-ethyl-5-((5-methylisoxazol-3- yl)oxy)pheny...) Show SMILES CCc1ccc(Oc2cc(C)on2)cc1-c1cnc(NC(=O)c2cnccc2C)cn1 Show InChI InChI=1S/C23H21N5O3/c1-4-16-5-6-17(30-22-9-15(3)31-28-22)10-18(16)20-12-26-21(13-25-20)27-23(29)19-11-24-8-7-14(19)2/h5-13H,4H2,1-3H3,(H,26,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412407 (N-(5-(2-chloro-5-(2-methyl-2H- tetrazol-5-yl)pheny...) Show SMILES Cc1ccncc1C(=O)Nc1ccc(cn1)-c1cc(ccc1Cl)-c1nnn(C)n1 Show InChI InChI=1S/C20H16ClN7O/c1-12-7-8-22-11-16(12)20(29)24-18-6-4-14(10-23-18)15-9-13(3-5-17(15)21)19-25-27-28(2)26-19/h3-11H,1-2H3,(H,23,24,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412463 (N-(5-(5-ethyl-2-(5-methylisoxazol-3- yl)thiazol-4-...) Show SMILES CCc1sc(nc1-c1ccc(NC(=O)c2cncc(c2C)[N+]([O-])=O)nc1)-c1cc(C)on1 Show InChI InChI=1S/C21H18N6O4S/c1-4-17-19(25-21(32-17)15-7-11(2)31-26-15)13-5-6-18(23-8-13)24-20(28)14-9-22-10-16(12(14)3)27(29)30/h5-10H,4H2,1-3H3,(H,23,24,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412513 ((Z)-N-(5-(1-(4-bromophenyl)prop-1- en-1-yl)pyrazin...) Show SMILES C\C=C(\c1ccc(Br)cc1)c1cnc(NC(=O)c2cncc(F)c2C)cn1 Show InChI InChI=1S/C20H16BrFN4O/c1-3-15(13-4-6-14(21)7-5-13)18-10-25-19(11-24-18)26-20(27)16-8-23-9-17(22)12(16)2/h3-11H,1-2H3,(H,25,26,27)/b15-3-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412490 (N-(5-(2-chloro-5-(1-methyl-1H- pyrazol-4-yl)phenyl...) Show SMILES Cc1c(F)cncc1C(=O)Nc1cnc(cn1)-c1cc(ccc1Cl)-c1cnn(C)c1 Show InChI InChI=1S/C21H16ClFN6O/c1-12-16(7-24-8-18(12)23)21(30)28-20-10-25-19(9-26-20)15-5-13(3-4-17(15)22)14-6-27-29(2)11-14/h3-11H,1-2H3,(H,26,28,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412473 ((Z)-methyl 4-(1-(6-(5-fluoro-4- methylnicotinamido...) Show SMILES COC(=O)c1ccc(cc1)C(=C\C)\c1ccc(NC(=O)c2cncc(F)c2C)nc1 Show InChI InChI=1S/C23H20FN3O3/c1-4-18(15-5-7-16(8-6-15)23(29)30-3)17-9-10-21(26-11-17)27-22(28)19-12-25-13-20(24)14(19)2/h4-13H,1-3H3,(H,26,27,28)/b18-4-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412394 (N-(5-(2-chloro-5-(3-fluoropyridin-4- yl)phenyl)pyr...) Show SMILES Cc1ccncc1C(=O)Nc1cnc(cn1)-c1cc(ccc1Cl)-c1ccncc1F Show InChI InChI=1S/C22H15ClFN5O/c1-13-4-6-25-9-17(13)22(30)29-21-12-27-20(11-28-21)16-8-14(2-3-18(16)23)15-5-7-26-10-19(15)24/h2-12H,1H3,(H,28,29,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412453 ((Z)-N-(5-(1-(4-bromophenyl)prop-1- en-1-yl)pyrazin...) Show SMILES C\C=C(\c1ccc(Br)cc1)c1cnc(NC(=O)c2cnccc2C)cn1 Show InChI InChI=1S/C20H17BrN4O/c1-3-16(14-4-6-15(21)7-5-14)18-11-24-19(12-23-18)25-20(26)17-10-22-9-8-13(17)2/h3-12H,1-2H3,(H,24,25,26)/b16-3-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412376 (5-fluoro-N-(5-(2-methoxy-5-(1- methyl-1H-pyrazol-4...) Show SMILES COc1ccc(cc1-c1cnc(NC(=O)c2cncc(F)c2C)cn1)-c1cnn(C)c1 Show InChI InChI=1S/C22H19FN6O2/c1-13-17(8-24-9-18(13)23)22(30)28-21-11-25-19(10-26-21)16-6-14(4-5-20(16)31-3)15-7-27-29(2)12-15/h4-12H,1-3H3,(H,26,28,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412498 (N-(5-(2-chloro-5-(1-methyl-1H- pyrazol-4-yl)phenyl...) Show SMILES CCc1cncc(C(=O)Nc2cnc(cn2)-c2cc(ccc2Cl)-c2cnn(C)c2)c1C Show InChI InChI=1S/C23H21ClN6O/c1-4-15-8-25-10-19(14(15)2)23(31)29-22-12-26-21(11-27-22)18-7-16(5-6-20(18)24)17-9-28-30(3)13-17/h5-13H,4H2,1-3H3,(H,27,29,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412418 (N-(5-(2-ethyl-5-(2-methyl-2H- tetrazol-5-yl)phenyl...) Show SMILES CCc1ccc(cc1-c1ccc(NC(=O)c2cnccc2C)nc1)-c1nnn(C)n1 Show InChI InChI=1S/C22H21N7O/c1-4-15-5-6-16(21-26-28-29(3)27-21)11-18(15)17-7-8-20(24-12-17)25-22(30)19-13-23-10-9-14(19)2/h5-13H,4H2,1-3H3,(H,24,25,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412423 (N-(5-(2-chloro-5-(1-methyl-1H- pyrazol-4-yl)phenyl...) Show SMILES Cc1ccncc1C(=O)Nc1cnc(cn1)-c1cc(ccc1Cl)-c1cnn(C)c1 Show InChI InChI=1S/C21H17ClN6O/c1-13-5-6-23-9-17(13)21(29)27-20-11-24-19(10-25-20)16-7-14(3-4-18(16)22)15-8-26-28(2)12-15/h3-12H,1-2H3,(H,25,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair
Interleukin-2 (Homo sapiens (Human))	BDBM412507 ((E)-N-(5-(1-(6-ethoxypyridin-3- yl)prop-1-en-1-yl)...) Show SMILES CCOc1ccc(cn1)C(=C\C)\c1ccc(NC(=O)c2cncc(F)c2C)nc1 Show InChI InChI=1S/C22H21FN4O2/c1-4-17(16-7-9-21(26-11-16)29-5-2)15-6-8-20(25-10-15)27-22(28)18-12-24-13-19(23)14(18)3/h4,6-13H,5H2,1-3H3,(H,25,27,28)/b17-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
PRCL RESEARCH INC. US Patent					Assay Description Human peripheral blood mononuclear cells (PBMCs) are prepared from heparinized human blood by separation over a Ficoll density gradient.PBMCs are sti...				US Patent US10399967 (2019) BindingDB Entry DOI: 10.7270/Q2Z89FRQ
					More data for this Ligand-Target Pair

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