BindingDB PrimarySearch

Found 11 hits of ec50 data for polymerid = 6432
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50470944 (CHEMBL336161) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.20	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro agonist potency towards Alpha-1A adrenergic receptor in rat vas deferens				J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50118703 (CHEMBL109783 \| N-[5-(4,5-Dihydro-1H-imidazol-2-yl)...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	n/a	n/a	n/a	n/a	5.80	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro agonist potency towards Alpha-1A adrenergic receptor in rat vas deferens				J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM30712 (6-tert-butyl-3-(2-imidazolin-2-ylmethyl)-2,4-dimet...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	288	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro agonist potency towards Alpha-1A adrenergic receptor in rat vas deferens				J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50131411 (4-(4-Chloro-benzyl)-2-methyl-2H-phthalazin-1-one \|...) Show SMILES Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	810	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description Vasorelaxation of noradrenaline-stimulated Wistar rat vas deferens contraction				Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N
Universidad de Salamanca Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50029051 ((-)-arterenol \| (-)-noradrenaline \| (-)-norepineph...) Show SMILES NC[C@H](O)c1ccc(O)c(O)c1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro agonist potency towards Alpha-1A adrenergic receptor in rat vas deferens				J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50131423 (4-Benzyl-2-methyl-2H-phthalazin-1-one \| 4-benzyl-2...) Show SMILES Cn1nc(Cc2ccccc2)c2ccccc2c1=O Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description Vasorelaxation of noradrenaline-stimulated Wistar rat vas deferens contraction				Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N
Universidad de Salamanca Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50067212 (CHEBI:8093 \| Cyclomydril \| Duo-Medihaler \| Phenyle...) Show SMILES CNC[C@H](O)c1cccc(O)c1 \|r\| Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro agonist potency towards Alpha-1A adrenergic receptor in rat vas deferens				J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50131414 (4-(benzo[d][1,3]dioxol-5-ylmethyl)phthalazin-1(2H)...) Show SMILES O=c1[nH]nc(Cc2ccc3OCOc3c2)c2ccccc12 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description Vasorelaxation of noradrenaline-stimulated Wistar rat vas deferens contraction				Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N
Universidad de Salamanca Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM56339 (4-(4-chlorobenzyl)-1(2H)-phthalazinone \| 4-(4-chlo...) Show SMILES Clc1ccc(Cc2n[nH]c(=O)c3ccccc23)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description Vasorelaxation of noradrenaline-stimulated Wistar rat vas deferens contraction				Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N
Universidad de Salamanca Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50183665 (4-(4-chlorobenzyl)-2-allylphthalazin-1(2H)-one \| C...) Show SMILES Clc1ccc(Cc2nn(CC=C)c(=O)c3ccccc23)cc1 Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a
Universidad de Salamanca Curated by ChEMBL					Assay Description Vasorelaxation of noradrenaline-stimulated Wistar rat vas deferens contraction				Bioorg Med Chem Lett 16: 2786-90 (2006) Article DOI: 10.1016/j.bmcl.2006.02.003 BindingDB Entry DOI: 10.7270/Q22R3R8N
Universidad de Salamanca Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM50470943 (CHEMBL133451) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	n/a	n/a	3.09E+4	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description In vitro agonist potency towards Alpha-1A adrenergic receptor in rat vas deferens				J Med Chem 39: 4116-9 (1996) Article DOI: 10.1021/jm960354u BindingDB Entry DOI: 10.7270/Q2FN18WJ
Abbott Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)