Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134505 (US8846656, 21-D) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134531 (US8846656, 23-I) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50462093 (CHEMBL4245250) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Antagonist activity at C5aR1 in human U937 cells assessed as inhibition of recombinant human C5a-induced cell degranulation preincubated for 30 mins ... | J Med Chem 61: 3253-3276 (2018) Article DOI: 10.1021/acs.jmedchem.7b00882 BindingDB Entry DOI: 10.7270/Q2MK6GJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134511 (US8846656, 21-Q) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50462093 (CHEMBL4245250) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Antagonist activity at C5aR1 in human blood granulocytes assessed as inhibition of recombinant human C5a-induced CD11b expression on granulocytes pre... | J Med Chem 61: 3253-3276 (2018) Article DOI: 10.1021/acs.jmedchem.7b00882 BindingDB Entry DOI: 10.7270/Q2MK6GJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50462093 (CHEMBL4245250) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Antagonist activity at C5aR1 in human HL60 cells assessed as inhibition of recombinant human C5a-induced oxidative burst after 30 mins by fluorescenc... | J Med Chem 61: 3253-3276 (2018) Article DOI: 10.1021/acs.jmedchem.7b00882 BindingDB Entry DOI: 10.7270/Q2MK6GJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50462093 (CHEMBL4245250) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Antagonist activity at C5aR1 in human U937 cells assessed as inhibition of recombinant human C5a-induced chemotaxis preincubated for 30 mins followed... | J Med Chem 61: 3253-3276 (2018) Article DOI: 10.1021/acs.jmedchem.7b00882 BindingDB Entry DOI: 10.7270/Q2MK6GJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50462093 (CHEMBL4245250) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Antagonist activity at C5aR1 in human U937 cells assessed as inhibition of recombinant human C5a-induced intracellular calcium mobilization preincuba... | J Med Chem 61: 3253-3276 (2018) Article DOI: 10.1021/acs.jmedchem.7b00882 BindingDB Entry DOI: 10.7270/Q2MK6GJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50462093 (CHEMBL4245250) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Antagonist activity at recombinant human C5aR1 expressed in Sf9 insect cell membranes co-expressing G-alphai2,G-beta1 and G-gamma2 assessed as inhibi... | J Med Chem 61: 3253-3276 (2018) Article DOI: 10.1021/acs.jmedchem.7b00882 BindingDB Entry DOI: 10.7270/Q2MK6GJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50462093 (CHEMBL4245250) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Antagonist activity at C5aR1 in human neutrophils assessed as inhibition of recombinant human C5a-induced chemotaxis preincubated for 30 mins followe... | J Med Chem 61: 3253-3276 (2018) Article DOI: 10.1021/acs.jmedchem.7b00882 BindingDB Entry DOI: 10.7270/Q2MK6GJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134574 (US8846656, 55-I) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134520 (US8846656, 21-AI) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134569 (US8846656, 52-C) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134577 (US8846656, 55-M) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134580 (US8846656, 56-C) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134582 (US8846656, 56-F) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134524 (US8846656, 21-AM) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134523 (US8846656, 21-AL) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134586 (US8846656, 65-A) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134596 (US8846656, 69-L) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134589 (US8846656, 65-I) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134512 (US8846656, 21-R) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134530 (US8846656, 23-H) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134519 (US8846656, 21-AH) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134518 (US8846656, 21-AG) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134500 (US8846656, 19-AF) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50275728 (CHEMBL486749 | N-(4-chlorophenethyl)-2-isobutyl-N-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cells | Bioorg Med Chem Lett 18: 5601-4 (2008) Article DOI: 10.1016/j.bmcl.2008.08.106 BindingDB Entry DOI: 10.7270/Q2TQ61CX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50462086 (CHEMBL1628668) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Antagonist activity at C5aR1 in human neutrophils assessed as inhibition of 0.1 nM recombinant human C5a-induced intracellular calcium release | J Med Chem 61: 3253-3276 (2018) Article DOI: 10.1021/acs.jmedchem.7b00882 BindingDB Entry DOI: 10.7270/Q2MK6GJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134502 (US8846656, 19-AI) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134572 (US8846656, 55-G) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134579 (US8846656, 56-B) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134509 (US8846656, 21-N) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134507 (US8846656, 21-K) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134581 (US8846656, 56-E) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134591 (US8846656, 68-B) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134587 (US8846656, 65-B) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134590 (US8846656, 65-K) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134601 (US8846656, 71-B) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134546 (US8846656, 29) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134525 (US8846656, 22-C) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134571 (US8846656, 54-B) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134479 (US8846656, 17-AM) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134529 (US8846656, 23-G) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134498 (US8846656, 19-AD) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134551 (US8846656, 32-B) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50462086 (CHEMBL1628668) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Antagonist activity at C5aR1 in HMDM assessed as inhibition of 1 nM recombinant human C5a-induced intracellular calcium release preincubated for 1 hr... | J Med Chem 61: 3253-3276 (2018) Article DOI: 10.1021/acs.jmedchem.7b00882 BindingDB Entry DOI: 10.7270/Q2MK6GJ9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM50266072 ((+/-)-ethyl 2-(N-(1,4-dioxaspiro[4.5]decan-8-yl)-1...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [125I]C5a from C5a receptor in cAMP differentiated human U937 cells by filtration assay | Bioorg Med Chem Lett 18: 5605-8 (2008) Article DOI: 10.1016/j.bmcl.2008.08.101 BindingDB Entry DOI: 10.7270/Q2M61K31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134562 (US8846656, 41-G) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134544 (US8846656, 28-B) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human)) | BDBM134576 (US8846656, 55-L) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis AG US Patent | Assay Description Compounds were tested for their ability to inhibit C5a-mediated calcium mobilization using a stable cell line over expressing the human C5aR & the Ga... | US Patent US8846656 (2014) BindingDB Entry DOI: 10.7270/Q2JW8CKR | |||||||||||
More data for this Ligand-Target Pair |
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