Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031386 ((S)-2-{(S)-2-[(S)-2-[(S)-2-((S)-2-Amino-propionyla...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031422 ((S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-propionyla...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 30 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activity of Radio-ligand Peptides upon the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50054858 (CHEMBL144504 | Thiophene-2-carboxylic acid [1-[1-[...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Concentration of compound required to inhibit agonist (SFFLRR-NH2, at 3 uM) induced platelet aggregation by 50% | J Med Chem 39: 4879-87 (1997) Article DOI: 10.1021/jm960455s BindingDB Entry DOI: 10.7270/Q26W9BRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031382 ((S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-propionyla...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031432 ((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031427 ((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-(4-flu...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 140 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031380 ((S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-propionyla...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 150 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activity of Radio-ligand Peptides upon the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031406 ((S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-propionyla...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 160 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031406 ((S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-propionyla...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 160 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50440859 (CHEMBL2431718) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 180 | n/a | n/a | n/a | n/a |
The University of Queensland Curated by ChEMBL | Assay Description Agonist activity at human PAR1 expressed in African green monkey COS7 cells assessed as stimulation of inositol triphosphate production | J Med Chem 56: 7477-97 (2013) Article DOI: 10.1021/jm400638v BindingDB Entry DOI: 10.7270/Q2NC62MG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031413 ((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-(4-flu...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031392 ((S)-2-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-3-h...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50054859 (2-{(R)-2-[2-(3-Acetylamino-propionylamino)-3-(4-fl...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 270 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Effective concentration for stimulation of platelet aggregation | J Med Chem 39: 4879-87 (1997) Article DOI: 10.1021/jm960455s BindingDB Entry DOI: 10.7270/Q26W9BRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031398 ((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-(3,4-d...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 270 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031392 ((S)-2-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-3-h...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 280 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031398 ((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-(3,4-d...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 300 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activity of Radio-ligand Peptides upon the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031424 ((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-phenyl...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 400 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077726 (5-Bromo-N-{(S)-1-[(S)-1-((S)-1-carbamoyl-2-phenyl-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 460 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031397 ((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-(3,4-d...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 500 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031414 (1-{(S)-2-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 500 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077747 (4-Oxo-4H-chromene-2-carboxylic acid {(S)-1-[(S)-1-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 510 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031407 ((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-(4-chl...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 700 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50454438 (CHEMBL2370948) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 720 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Effective concentration for stimulation of platelet aggregation | J Med Chem 39: 4879-87 (1997) Article DOI: 10.1021/jm960455s BindingDB Entry DOI: 10.7270/Q26W9BRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077752 (5-((E)-2-Methyl-3-phenyl-acryloylamino)-1H-[1,2,4]...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 760 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077748 (5-Amino-1H-[1,2,4]triazole-3-carboxylic acid {(S)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | n/a | n/a | 760 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031417 ((S)-2-[(S)-2-((S)-2-Amino-propionylamino)-3-phenyl...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 800 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031381 ((S)-2-[(S)-2-((S)-2-Amino-3-hydroxy-propionylamino...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077738 (5-((E)-3-Naphthalen-1-yl-acryloylamino)-1H-[1,2,4]...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077743 (CHEMBL33532 | Quinoxaline-2-carboxylic acid {(S)-1...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077744 (5-Amino-1H-[1,2,4]triazole-3-carboxylic acid {(S)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to thrombin receptor (PAR-1) on membranes from CHRF cells | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077741 (5-[(E)-3-(2-Chloro-phenyl)-acryloylamino]-1H-[1,2,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077728 (Biphenylene-2-carboxylic acid {(S)-1-[(S)-1-((S)-1...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077750 (6-Amino-N-{(S)-1-[(S)-1-((S)-1-carbamoyl-2-phenyl-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031401 ((S)-2-[(S)-2-(2-Amino-acetylamino)-3-phenyl-propio...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077732 (CHEMBL285018 | [1,2,3]Thiadiazole-4-carboxylic aci...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031405 ((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-3-hydroxy-propion...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031386 ((S)-2-{(S)-2-[(S)-2-[(S)-2-((S)-2-Amino-propionyla...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activity of Radio-ligand Peptides upon the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077749 (5-((Z)-2-Fluoro-3-phenyl-acryloylamino)-1H-[1,2,4]...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50054870 (1H-Indole-2-carboxylic acid [1-[1-[1-(1-carbamoyl-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Effective concentration for stimulation of platelet aggregation | J Med Chem 39: 4879-87 (1997) Article DOI: 10.1021/jm960455s BindingDB Entry DOI: 10.7270/Q26W9BRV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077751 (5-[(E)-3-(2-Nitro-phenyl)-acryloylamino]-1H-[1,2,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to thrombin receptor (PAR-1) on membranes from CHRF cells | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077740 (5-[(E)-3-(3-Nitro-phenyl)-acryloylamino]-1H-[1,2,4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077730 (CHEMBL284498 | N-{(S)-1-[(S)-1-((S)-1-Carbamoyl-2-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031420 (CHEMBL263369 | SFLLRDPQDK-NH2) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Evaluated for the activation of human thrombin receptor measured by platelet aggregation | J Med Chem 38: 4125-30 (1995) BindingDB Entry DOI: 10.7270/Q21J98SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077746 (5-Amino-1H-[1,2,4]triazole-3-carboxylic acid {(S)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077759 (5-[(E)-3-(3-Chloro-phenyl)-acryloylamino]-1H-[1,2,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077754 ((S)-2-[(S)-3-Cyclohexyl-2-((E)-3-pyridin-3-yl-acry...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077764 (3-Amino-N-{(S)-1-[(S)-1-((S)-1-carbamoyl-2-phenyl-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077763 (5-((E)-3-Thiophen-2-yl-acryloylamino)-1H-[1,2,4]tr...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Activation of human platelet aggregation (gel-filtered platelets) induced by alpha thrombin | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50031414 (1-{(S)-2-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a |
TBA | Assay Description Activation of PAR-1 in human platelet-rich plasma assessed as induction of platelet aggregation by turbidimetric method | Citation and Details Article DOI: 10.1016/j.bmc.2021.116498 BindingDB Entry DOI: 10.7270/Q2HH6PZJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Proteinase-activated receptor 1 (Homo sapiens (Human)) | BDBM50077720 (5-Amino-1H-[1,2,4]triazole-3-carboxylic acid ((S)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | 3.10E+3 | n/a | n/a | n/a | n/a |
The R. W. Johnson Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of [3H]-S-(p-F-Phe)-Har-L-Har-KY-NH2 binding to thrombin receptor (PAR-1) on membranes from CHRF cells | Bioorg Med Chem Lett 9: 1423-8 (1999) BindingDB Entry DOI: 10.7270/Q2R78DFP | |||||||||||
More data for this Ligand-Target Pair |
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