Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM227589 (Radicicol) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 1.86E+4 | n/a | n/a | n/a | 7.5 | 15 |
University of Texas Southwestern Medical Center | Assay Description The PDK2 or Hsp90 N-terminal domain protein was dialyzed against 1 liter of thedialysis buffer containing 50 mM Tris-Cl, pH 7.5, 50 mM KCl, 1 mM MgCl... | J Biol Chem 289: 4432-43 (2014) Article DOI: 10.1074/jbc.M113.533885 BindingDB Entry DOI: 10.7270/Q2N58K7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM81912 (DC23 | Resorcinol analog, 1) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 6.76E+3 | n/a | n/a | n/a | 7.5 | 15 |
University of Texas Southwestern Medical Center | Assay Description The PDK2 or Hsp90 N-terminal domain protein was dialyzed against 1 liter of thedialysis buffer containing 50 mM Tris-Cl, pH 7.5, 50 mM KCl, 1 mM MgCl... | J Biol Chem 289: 4432-43 (2014) Article DOI: 10.1074/jbc.M113.533885 BindingDB Entry DOI: 10.7270/Q2N58K7F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM227590 (PA1) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 3.57E+3 | n/a | n/a | n/a | 7.5 | 15 |
University of Texas Southwestern Medical Center | Assay Description The PDK2 or Hsp90 N-terminal domain protein was dialyzed against 1 liter of thedialysis buffer containing 50 mM Tris-Cl, pH 7.5, 50 mM KCl, 1 mM MgCl... | J Biol Chem 289: 4432-43 (2014) Article DOI: 10.1074/jbc.M113.533885 BindingDB Entry DOI: 10.7270/Q2N58K7F | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM227591 (PA7) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 1.83E+3 | n/a | n/a | n/a | 7.5 | 15 |
University of Texas Southwestern Medical Center | Assay Description The PDK2 or Hsp90 N-terminal domain protein was dialyzed against 1 liter of thedialysis buffer containing 50 mM Tris-Cl, pH 7.5, 50 mM KCl, 1 mM MgCl... | J Biol Chem 289: 4432-43 (2014) Article DOI: 10.1074/jbc.M113.533885 BindingDB Entry DOI: 10.7270/Q2N58K7F | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM227592 (PS2) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 711 | n/a | n/a | n/a | 7.5 | 15 |
University of Texas Southwestern Medical Center | Assay Description The PDK2 or Hsp90 N-terminal domain protein was dialyzed against 1 liter of thedialysis buffer containing 50 mM Tris-Cl, pH 7.5, 50 mM KCl, 1 mM MgCl... | J Biol Chem 289: 4432-43 (2014) Article DOI: 10.1074/jbc.M113.533885 BindingDB Entry DOI: 10.7270/Q2N58K7F | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM227593 (PS8) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 426 | n/a | n/a | n/a | 7.5 | 15 |
University of Texas Southwestern Medical Center | Assay Description The PDK2 or Hsp90 N-terminal domain protein was dialyzed against 1 liter of thedialysis buffer containing 50 mM Tris-Cl, pH 7.5, 50 mM KCl, 1 mM MgCl... | J Biol Chem 289: 4432-43 (2014) Article DOI: 10.1074/jbc.M113.533885 BindingDB Entry DOI: 10.7270/Q2N58K7F | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM227594 (PS10) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 239 | n/a | n/a | n/a | 7.5 | 15 |
University of Texas Southwestern Medical Center | Assay Description The PDK2 or Hsp90 N-terminal domain protein was dialyzed against 1 liter of thedialysis buffer containing 50 mM Tris-Cl, pH 7.5, 50 mM KCl, 1 mM MgCl... | J Biol Chem 289: 4432-43 (2014) Article DOI: 10.1074/jbc.M113.533885 BindingDB Entry DOI: 10.7270/Q2N58K7F | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM227593 (PS8) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 426 | n/a | n/a | n/a | n/a | n/a |
National Institute of Biological Science Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-SUMO tagged recombinant human PDK2 by isothermal titration calorimetry | J Med Chem 60: 1142-1150 (2017) Article DOI: 10.1021/acs.jmedchem.6b01540 BindingDB Entry DOI: 10.7270/Q2BP0514 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM227594 (PS10) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 156 | n/a | n/a | n/a | n/a | n/a |
National Institute of Biological Science Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-SUMO tagged recombinant human PDK2 by isothermal titration calorimetry | J Med Chem 60: 1142-1150 (2017) Article DOI: 10.1021/acs.jmedchem.6b01540 BindingDB Entry DOI: 10.7270/Q2BP0514 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM50232913 (CHEMBL4103350) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a |
National Institute of Biological Science Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-SUMO tagged recombinant human PDK2 by isothermal titration calorimetry | J Med Chem 60: 1142-1150 (2017) Article DOI: 10.1021/acs.jmedchem.6b01540 BindingDB Entry DOI: 10.7270/Q2BP0514 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM50232905 (CHEMBL4091824) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a |
National Institute of Biological Science Curated by ChEMBL | Assay Description Binding affinity to N-terminal His6-SUMO tagged recombinant human PDK2 by isothermal titration calorimetry | J Med Chem 60: 1142-1150 (2017) Article DOI: 10.1021/acs.jmedchem.6b01540 BindingDB Entry DOI: 10.7270/Q2BP0514 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414830 (1-((R)-3,3,3-Trifluoro-2-hydroxy-2-methyl-propiony...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414831 (1-((R)-3,3,3-Trifluoro-2-hydroxy-2-methyl-propiony...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414832 (1-((R)-3,3,3-Trifluoro-2-hydroxy-2-methyl-propiony...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414833 (1-((R)-3,3,3-Trifluoro-2-hydroxy-2-methyl-propiony...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414834 (1-((R)-3,3,3-Trifluoro-2-hydroxy-2-methyl-propiony...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414836 ((3S,4S)—N,3-Dimethyl-N-(4-methylphenyl)-1-[(2R)-3,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414838 (N-(4-chlorophenyl)-N,3-dimethyl-1-[(2R)-3,3,3-trif...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414839 ((3S,4S)—N-(4-chlorophenyl)-N,3-dimethyl-1-[(2R)-3,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414842 ((3S,4S)—N-(2-fluoro-4-methylphenyl)-N,3-dimethyl-1...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414843 ((3R,4R)—N-(2-fluoro-4-methylphenyl)-N,3-dimethyl-1...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414846 (4-Chloro-N-methyl-N-{1-[(2R)-3,3,3-trifluoro-2-hyd...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 154 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414847 (N,4-Dimethyl-N-{1-[(2R)-3,3,3-trifluoro-2-hydroxy-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414848 (2-Fluoro-4,N-dimethyl-N-{1-[(R)-3,3,3-trifluoro-2-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414849 (2-Chloro-N-methyl-N-{1-[(2R)-3,3,3-trifluoro-2-hyd...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414851 (4-Chloro-N-methyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414853 (N,4-Dimethyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3,3-tri...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414855 (2-Fluoro-N,4-dimethyl-N-[(3R,4S)-3-methyl-1-[(2R)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414856 (4-Fluoro-N-methyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414858 (N-Methyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3,3-trifluo...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414860 (4-Methoxy-N-methyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414862 (2,4-Difluoro-N-methyl-N-[(3R,4S)-3-methyl-1-[(2R)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414864 (3,5-Difluoro-N-methyl-N-[(3R,4S)-3-methyl-1-[(2R)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414866 (4-Cyano-N-methyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3,3...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414868 (2-Fluoro-N-methyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414870 (2-Chloro-4-fluoro-N-methyl-N-[(3R,4S)-3-methyl-1-[...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414872 (5-Fluoro-N-methyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3,...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414874 (N,1-Dimethyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3,3-tri...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414876 (4-Chloro-2-fluoro-N-methyl-N-[(3R,4S)-3-methyl-1-[...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414878 (N-Methyl-N-[(3R,4S)-3-methyl-1-[(2R)-3,3,3-trifluo...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414880 (N-Ethyl-2-fluoro-4-methyl-N-[1-((R)-3,3,3-trifluor...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414881 (2-Fluoro-N-isopropyl-4-methyl-N-[1-((R)-3,3,3-trif...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414882 (4-Cyano-N-ethyl-N-[1-((R)-3,3,3-trifluoro-2-hydrox...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM414883 (4-Cyano-N-isopropyl-N-[1-((R)-3,3,3-trifluoro-2-hy...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a |
MERCK PATENT GMBH US Patent | Assay Description ITC measurements were performed with a VP-ITC micro calorimeter (Microcal, LLC/GE Healthcare Bio-Sciences AB, Uppsala, Sweden). In general titrations... | US Patent US10428024 (2019) BindingDB Entry DOI: 10.7270/Q2ZW1P8H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM426364 (US10526325, Compound A40 | US10829489, Compound A4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <300 | n/a | n/a | n/a | n/a | n/a |
Merck Patent GmbH US Patent | Assay Description The biochemical activity assay for PDHK2 is based on the inactivation of PDC through phosphorylation by PDHK2. The assay is run in two steps: the enz... | US Patent US10526325 (2020) BindingDB Entry DOI: 10.7270/Q22Z17ZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM426366 (US10526325, Compound A42 | US10829489, Compound A4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <300 | n/a | n/a | n/a | n/a | n/a |
Merck Patent GmbH US Patent | Assay Description The biochemical activity assay for PDHK2 is based on the inactivation of PDC through phosphorylation by PDHK2. The assay is run in two steps: the enz... | US Patent US10526325 (2020) BindingDB Entry DOI: 10.7270/Q22Z17ZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM426367 (US10526325, Compound A43) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <300 | n/a | n/a | n/a | n/a | n/a |
Merck Patent GmbH US Patent | Assay Description The biochemical activity assay for PDHK2 is based on the inactivation of PDC through phosphorylation by PDHK2. The assay is run in two steps: the enz... | US Patent US10526325 (2020) BindingDB Entry DOI: 10.7270/Q22Z17ZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM426368 (US10526325, Compound A44 | US10829489, Compound A4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <300 | n/a | n/a | n/a | n/a | n/a |
Merck Patent GmbH US Patent | Assay Description The biochemical activity assay for PDHK2 is based on the inactivation of PDC through phosphorylation by PDHK2. The assay is run in two steps: the enz... | US Patent US10526325 (2020) BindingDB Entry DOI: 10.7270/Q22Z17ZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM426369 (US10526325, Compound A45 | US10829489, Compound A4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <300 | n/a | n/a | n/a | n/a | n/a |
Merck Patent GmbH US Patent | Assay Description The biochemical activity assay for PDHK2 is based on the inactivation of PDC through phosphorylation by PDHK2. The assay is run in two steps: the enz... | US Patent US10526325 (2020) BindingDB Entry DOI: 10.7270/Q22Z17ZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Homo sapiens (Human)) | BDBM426370 (US10526325, Compound A46 | US10829489, Compound A4...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | <300 | n/a | n/a | n/a | n/a | n/a |
Merck Patent GmbH US Patent | Assay Description The biochemical activity assay for PDHK2 is based on the inactivation of PDC through phosphorylation by PDHK2. The assay is run in two steps: the enz... | US Patent US10526325 (2020) BindingDB Entry DOI: 10.7270/Q22Z17ZQ | |||||||||||
More data for this Ligand-Target Pair |
Displayed 1 to 50 (of 154 total ) | Next | Last >> |