Compile Data Set for Download or QSAR

Found 2263 hits of ic50 for UniProtKB: P53634   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201017 (US9540373, 6 | US9879026, Example 6 | USRE47636, E...) Show SMILES CN1CCC2(CC1)C(=O)Nc1ccc(cc21)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C29H32FN5O2/c1-35-10-8-29(9-11-35)23-14-17(5-7-25(23)34-28(29)37)18-2-3-19(24(30)15-18)12-22(16-31)33-27(36)26-20-4-6-21(13-20)32-26/h2-3,5,7,14-15,20-22,26,32H,4,6,8-13H2,1H3,(H,33,36)(H,34,37)/t20-,21+,22-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...				US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201017 (US9540373, 6 | US9879026, Example 6 | USRE47636, E...) Show SMILES CN1CCC2(CC1)C(=O)Nc1ccc(cc21)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C29H32FN5O2/c1-35-10-8-29(9-11-35)23-14-17(5-7-25(23)34-28(29)37)18-2-3-19(24(30)15-18)12-22(16-31)33-27(36)26-20-4-6-21(13-20)32-26/h2-3,5,7,14-15,20-22,26,32H,4,6,8-13H2,1H3,(H,33,36)(H,34,37)/t20-,21+,22-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...				US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201017 (US9540373, 6 | US9879026, Example 6 | USRE47636, E...) Show SMILES CN1CCC2(CC1)C(=O)Nc1ccc(cc21)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C29H32FN5O2/c1-35-10-8-29(9-11-35)23-14-17(5-7-25(23)34-28(29)37)18-2-3-19(24(30)15-18)12-22(16-31)33-27(36)26-20-4-6-21(13-20)32-26/h2-3,5,7,14-15,20-22,26,32H,4,6,8-13H2,1H3,(H,33,36)(H,34,37)/t20-,21+,22-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				US Patent US9540373 (2017) BindingDB Entry DOI: 10.7270/Q2NK3C6R
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50195247 (CHEMBL3936580) Show SMILES CN1C(=O)Cc2ccc(cc12)-c1ccc(C[C@H](NC(=O)C2(N)CCOCC2)C#N)cc1 |r| Show InChI InChI=1S/C24H26N4O3/c1-28-21-13-18(6-7-19(21)14-22(28)29)17-4-2-16(3-5-17)12-20(15-25)27-23(30)24(26)8-10-31-11-9-24/h2-7,13,20H,8-12,14,26H2,1H3,(H,27,30)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.251	n/a	n/a	n/a	n/a	n/a	n/a
CHARLES RIVER DISCOVERY RESEARCH SERVICES UK LIMITED Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP1 using Gly-Arg-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorometric assay				J Med Chem 59: 9457-9472 (2016) Article DOI: 10.1021/acs.jmedchem.6b01127 BindingDB Entry DOI: 10.7270/Q2Z321K4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201014 (US9540373, 3 | US9879026, Example 3 | USRE47636, E...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2NC(=O)C3(CCNCC3)c2c1 |r| Show InChI InChI=1S/C28H30FN5O2/c29-23-14-17(16-4-6-24-22(13-16)28(27(36)34-24)7-9-31-10-8-28)1-2-18(23)11-21(15-30)33-26(35)25-19-3-5-20(12-19)32-25/h1-2,4,6,13-14,19-21,25,31-32H,3,5,7-12H2,(H,33,35)(H,34,36)/t19-,20+,21-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...				US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201014 (US9540373, 3 | US9879026, Example 3 | USRE47636, E...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2NC(=O)C3(CCNCC3)c2c1 |r| Show InChI InChI=1S/C28H30FN5O2/c29-23-14-17(16-4-6-24-22(13-16)28(27(36)34-24)7-9-31-10-8-28)1-2-18(23)11-21(15-30)33-26(35)25-19-3-5-20(12-19)32-25/h1-2,4,6,13-14,19-21,25,31-32H,3,5,7-12H2,(H,33,35)(H,34,36)/t19-,20+,21-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				US Patent US9540373 (2017) BindingDB Entry DOI: 10.7270/Q2NK3C6R
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM633586 (N—((S)-1-cyano-2-(3-fluoro-4′-(pentafluoro-1...) Show SMILES CO[C@@H]1CNC[C@H](OC1)C(=O)N[C@@H](Cc1ccc(cc1F)-c1ccc(cc1)S(F)(F)(F)(F)F)C#N |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201014 (US9540373, 3 | US9879026, Example 3 | USRE47636, E...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2NC(=O)C3(CCNCC3)c2c1 |r| Show InChI InChI=1S/C28H30FN5O2/c29-23-14-17(16-4-6-24-22(13-16)28(27(36)34-24)7-9-31-10-8-28)1-2-18(23)11-21(15-30)33-26(35)25-19-3-5-20(12-19)32-25/h1-2,4,6,13-14,19-21,25,31-32H,3,5,7-12H2,(H,33,35)(H,34,36)/t19-,20+,21-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...				US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50310682 ((S)-2-amino-N-((S)-1-cyano-2-(5-phenylthiophen-2-y...) Show SMILES N[C@@H](Cc1cccs1)C(=O)N[C@@H](Cc1ccc(s1)-c1ccccc1)C#N |r| Show InChI InChI=1S/C20H19N3OS2/c21-13-15(23-20(24)18(22)12-16-7-4-10-25-16)11-17-8-9-19(26-17)14-5-2-1-3-6-14/h1-10,15,18H,11-12,22H2,(H,23,24)/t15-,18-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Canada& Co. Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin C				Bioorg Med Chem Lett 19: 5392-6 (2009) Article DOI: 10.1016/j.bmcl.2009.07.114 BindingDB Entry DOI: 10.7270/Q298874W
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM50502619 (CHEMBL4561264) Show SMILES CS[C@@H]1CN[C@@H](C1)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccc(cc1)C#N)C#N |r| Show InChI InChI=1S/C22H22N4OS/c1-28-20-11-21(25-14-20)22(27)26-19(13-24)10-15-2-6-17(7-3-15)18-8-4-16(12-23)5-9-18/h2-9,19-21,25H,10-11,14H2,1H3,(H,26,27)/t19-,20-,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.398	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of recombinant human DPPI using H-Gly-Arg-AFC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins ...				ACS Med Chem Lett 10: 1222-1227 (2019) Article DOI: 10.1021/acsmedchemlett.9b00261 BindingDB Entry DOI: 10.7270/Q2WM1HPF
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201015 (US9540373, 4 | US9879026, Example 4 | USRE47636, E...) Show SMILES CN1C(=O)C2(CCNCC2)c2cc(ccc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C29H32FN5O2/c1-35-25-7-5-17(14-23(25)29(28(35)37)8-10-32-11-9-29)18-2-3-19(24(30)15-18)12-22(16-31)34-27(36)26-20-4-6-21(13-20)33-26/h2-3,5,7,14-15,20-22,26,32-33H,4,6,8-13H2,1H3,(H,34,36)/t20-,21+,22-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				US Patent US9540373 (2017) BindingDB Entry DOI: 10.7270/Q2NK3C6R
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201015 (US9540373, 4 | US9879026, Example 4 | USRE47636, E...) Show SMILES CN1C(=O)C2(CCNCC2)c2cc(ccc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C29H32FN5O2/c1-35-25-7-5-17(14-23(25)29(28(35)37)8-10-32-11-9-29)18-2-3-19(24(30)15-18)12-22(16-31)34-27(36)26-20-4-6-21(13-20)33-26/h2-3,5,7,14-15,20-22,26,32-33H,4,6,8-13H2,1H3,(H,34,36)/t20-,21+,22-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...				US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201015 (US9540373, 4 | US9879026, Example 4 | USRE47636, E...) Show SMILES CN1C(=O)C2(CCNCC2)c2cc(ccc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C29H32FN5O2/c1-35-25-7-5-17(14-23(25)29(28(35)37)8-10-32-11-9-29)18-2-3-19(24(30)15-18)12-22(16-31)34-27(36)26-20-4-6-21(13-20)33-26/h2-3,5,7,14-15,20-22,26,32-33H,4,6,8-13H2,1H3,(H,34,36)/t20-,21+,22-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...				US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201018 (US9540373, 7 | US9879026, Example 7 | USRE47636, E...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2C(=O)OC3(CCNCC3)c2c1 |r| Show InChI InChI=1S/C28H29FN4O3/c29-24-14-17(16-4-6-22-23(13-16)28(36-27(22)35)7-9-31-10-8-28)1-2-18(24)11-21(15-30)33-26(34)25-19-3-5-20(12-19)32-25/h1-2,4,6,13-14,19-21,25,31-32H,3,5,7-12H2,(H,33,34)/t19-,20+,21-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...				US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201027 (US9540373, 16 | US9879026, Example 16 | USRE47636,...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2NC(=O)C3(CCNC3)c2c1 |r| Show InChI InChI=1S/C27H28FN5O2/c28-22-12-16(15-4-6-23-21(11-15)27(26(35)33-23)7-8-30-14-27)1-2-17(22)9-20(13-29)32-25(34)24-18-3-5-19(10-18)31-24/h1-2,4,6,11-12,18-20,24,30-31H,3,5,7-10,14H2,(H,32,34)(H,33,35)/t18-,19+,20-,24-,27?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...				US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201023 (US9540373, 12 | US9879026, Example 12 | USRE47636,...) Show SMILES CN1CC2(C1)OC(=O)c1ccc(cc21)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C27H27FN4O3/c1-32-13-27(14-32)22-10-15(5-7-21(22)26(34)35-27)16-2-3-17(23(28)11-16)8-20(12-29)31-25(33)24-18-4-6-19(9-18)30-24/h2-3,5,7,10-11,18-20,24,30H,4,6,8-9,13-14H2,1H3,(H,31,33)/t18-,19+,20-,24-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...				US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201026 (US9540373, 15 | US9879026, Example 15 | USRE47636,...) Show SMILES CN1CCC2(CCc3ccc(cc23)-c2ccc(C[C@H](NC(=O)[C@H]3N[C@@H]4CC[C@H]3C4)C#N)c(F)c2)CC1 |r| Show InChI InChI=1S/C30H35FN4O/c1-35-12-10-30(11-13-35)9-8-19-2-3-20(16-26(19)30)21-4-5-22(27(31)17-21)14-25(18-32)34-29(36)28-23-6-7-24(15-23)33-28/h2-5,16-17,23-25,28,33H,6-15H2,1H3,(H,34,36)/t23-,24+,25-,28-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...				US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201027 (US9540373, 16 | US9879026, Example 16 | USRE47636,...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2NC(=O)C3(CCNC3)c2c1 |r| Show InChI InChI=1S/C27H28FN5O2/c28-22-12-16(15-4-6-23-21(11-15)27(26(35)33-23)7-8-30-14-27)1-2-17(22)9-20(13-29)32-25(34)24-18-3-5-19(10-18)31-24/h1-2,4,6,11-12,18-20,24,30-31H,3,5,7-10,14H2,(H,32,34)(H,33,35)/t18-,19+,20-,24-,27?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...				US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM633583 ((S)—N—((S)-1-cyano-2-(2-fluoro-4-(3-(methyl-d3)-2-...) Show SMILES Cn1c2cc(ccc2oc1=O)-c1ccc(C[C@H](NC(=O)[C@@H]2CNCCCO2)C#N)c(F)c1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201018 (US9540373, 7 | US9879026, Example 7 | USRE47636, E...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2C(=O)OC3(CCNCC3)c2c1 |r| Show InChI InChI=1S/C28H29FN4O3/c29-24-14-17(16-4-6-22-23(13-16)28(36-27(22)35)7-9-31-10-8-28)1-2-18(24)11-21(15-30)33-26(34)25-19-3-5-20(12-19)32-25/h1-2,4,6,13-14,19-21,25,31-32H,3,5,7-12H2,(H,33,34)/t19-,20+,21-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				US Patent US9540373 (2017) BindingDB Entry DOI: 10.7270/Q2NK3C6R
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201020 (US9540373, 9 | US9879026, Example 9 | USRE47636, E...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2C(=O)OC3(CCNC3)c2c1 |r| Show InChI InChI=1S/C27H27FN4O3/c28-23-12-16(15-4-6-21-22(11-15)27(35-26(21)34)7-8-30-14-27)1-2-17(23)9-20(13-29)32-25(33)24-18-3-5-19(10-18)31-24/h1-2,4,6,11-12,18-20,24,30-31H,3,5,7-10,14H2,(H,32,33)/t18-,19+,20-,24-,27?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				US Patent US9540373 (2017) BindingDB Entry DOI: 10.7270/Q2NK3C6R
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201023 (US9540373, 12 | US9879026, Example 12 | USRE47636,...) Show SMILES CN1CC2(C1)OC(=O)c1ccc(cc21)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C27H27FN4O3/c1-32-13-27(14-32)22-10-15(5-7-21(22)26(34)35-27)16-2-3-17(23(28)11-16)8-20(12-29)31-25(33)24-18-4-6-19(9-18)30-24/h2-3,5,7,10-11,18-20,24,30H,4,6,8-9,13-14H2,1H3,(H,31,33)/t18-,19+,20-,24-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				US Patent US9540373 (2017) BindingDB Entry DOI: 10.7270/Q2NK3C6R
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201026 (US9540373, 15 | US9879026, Example 15 | USRE47636,...) Show SMILES CN1CCC2(CCc3ccc(cc23)-c2ccc(C[C@H](NC(=O)[C@H]3N[C@@H]4CC[C@H]3C4)C#N)c(F)c2)CC1 |r| Show InChI InChI=1S/C30H35FN4O/c1-35-12-10-30(11-13-35)9-8-19-2-3-20(16-26(19)30)21-4-5-22(27(31)17-21)14-25(18-32)34-29(36)28-23-6-7-24(15-23)33-28/h2-5,16-17,23-25,28,33H,6-15H2,1H3,(H,34,36)/t23-,24+,25-,28-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				US Patent US9540373 (2017) BindingDB Entry DOI: 10.7270/Q2NK3C6R
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201027 (US9540373, 16 | US9879026, Example 16 | USRE47636,...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2NC(=O)C3(CCNC3)c2c1 |r| Show InChI InChI=1S/C27H28FN5O2/c28-22-12-16(15-4-6-23-21(11-15)27(26(35)33-23)7-8-30-14-27)1-2-17(22)9-20(13-29)32-25(34)24-18-3-5-19(10-18)31-24/h1-2,4,6,11-12,18-20,24,30-31H,3,5,7-10,14H2,(H,32,34)(H,33,35)/t18-,19+,20-,24-,27?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				US Patent US9540373 (2017) BindingDB Entry DOI: 10.7270/Q2NK3C6R
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201018 (US9540373, 7 | US9879026, Example 7 | USRE47636, E...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2C(=O)OC3(CCNCC3)c2c1 |r| Show InChI InChI=1S/C28H29FN4O3/c29-24-14-17(16-4-6-22-23(13-16)28(36-27(22)35)7-9-31-10-8-28)1-2-18(24)11-21(15-30)33-26(34)25-19-3-5-20(12-19)32-25/h1-2,4,6,13-14,19-21,25,31-32H,3,5,7-12H2,(H,33,34)/t19-,20+,21-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...				US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201020 (US9540373, 9 | US9879026, Example 9 | USRE47636, E...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2C(=O)OC3(CCNC3)c2c1 |r| Show InChI InChI=1S/C27H27FN4O3/c28-23-12-16(15-4-6-21-22(11-15)27(35-26(21)34)7-8-30-14-27)1-2-17(23)9-20(13-29)32-25(33)24-18-3-5-19(10-18)31-24/h1-2,4,6,11-12,18-20,24,30-31H,3,5,7-10,14H2,(H,32,33)/t18-,19+,20-,24-,27?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...				US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201023 (US9540373, 12 | US9879026, Example 12 | USRE47636,...) Show SMILES CN1CC2(C1)OC(=O)c1ccc(cc21)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C27H27FN4O3/c1-32-13-27(14-32)22-10-15(5-7-21(22)26(34)35-27)16-2-3-17(23(28)11-16)8-20(12-29)31-25(33)24-18-4-6-19(9-18)30-24/h2-3,5,7,10-11,18-20,24,30H,4,6,8-9,13-14H2,1H3,(H,31,33)/t18-,19+,20-,24-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...				US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201026 (US9540373, 15 | US9879026, Example 15 | USRE47636,...) Show SMILES CN1CCC2(CCc3ccc(cc23)-c2ccc(C[C@H](NC(=O)[C@H]3N[C@@H]4CC[C@H]3C4)C#N)c(F)c2)CC1 |r| Show InChI InChI=1S/C30H35FN4O/c1-35-12-10-30(11-13-35)9-8-19-2-3-20(16-26(19)30)21-4-5-22(27(31)17-21)14-25(18-32)34-29(36)28-23-6-7-24(15-23)33-28/h2-5,16-17,23-25,28,33H,6-15H2,1H3,(H,34,36)/t23-,24+,25-,28-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...				US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201020 (US9540373, 9 | US9879026, Example 9 | USRE47636, E...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2C(=O)OC3(CCNC3)c2c1 |r| Show InChI InChI=1S/C27H27FN4O3/c28-23-12-16(15-4-6-21-22(11-15)27(35-26(21)34)7-8-30-14-27)1-2-17(23)9-20(13-29)32-25(33)24-18-3-5-19(10-18)31-24/h1-2,4,6,11-12,18-20,24,30-31H,3,5,7-10,14H2,(H,32,33)/t18-,19+,20-,24-,27?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...				US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201016 (US9540373, 5 | US9879026, Example 5 | USRE47636, E...) Show SMILES CN1C(=O)C2(CCN(C)CC2)c2cc(ccc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C30H34FN5O2/c1-35-11-9-30(10-12-35)24-15-18(6-8-26(24)36(2)29(30)38)19-3-4-20(25(31)16-19)13-23(17-32)34-28(37)27-21-5-7-22(14-21)33-27/h3-4,6,8,15-16,21-23,27,33H,5,7,9-14H2,1-2H3,(H,34,37)/t21-,22+,23-,27-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...				US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201013 (US9540373, 2 | US9879026, Example 2 | USRE47636, E...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2CCC3(CCNCC3)c2c1 |r| Show InChI InChI=1S/C29H33FN4O/c30-26-16-20(19-2-1-18-7-8-29(25(18)15-19)9-11-32-12-10-29)3-4-21(26)13-24(17-31)34-28(35)27-22-5-6-23(14-22)33-27/h1-4,15-16,22-24,27,32-33H,5-14H2,(H,34,35)/t22-,23+,24-,27-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...				US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201024 (US9540373, 13 | US9879026, Example 13 | USRE47636,...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2COC3(CCNCC3)c2c1 |r| Show InChI InChI=1S/C28H31FN4O2/c29-25-14-18(17-2-4-21-16-35-28(24(21)13-17)7-9-31-10-8-28)1-3-19(25)11-23(15-30)33-27(34)26-20-5-6-22(12-20)32-26/h1-4,13-14,20,22-23,26,31-32H,5-12,16H2,(H,33,34)/t20-,22+,23-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...				US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM150482 (US10238633, Example 156 | US8987249, 156 | US97136...) Show SMILES CC1(C)OC(=O)c2ccc(cc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C26H26FN3O3/c1-26(2)21-11-14(6-8-20(21)25(32)33-26)15-3-4-16(22(27)12-15)9-19(13-28)30-24(31)23-17-5-7-18(10-17)29-23/h3-4,6,8,11-12,17-19,23,29H,5,7,9-10H2,1-2H3,(H,30,31)/t17-,18+,19-,23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys...				US Patent US8987249 (2015) BindingDB Entry DOI: 10.7270/Q2KP80WG
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM150482 (US10238633, Example 156 | US8987249, 156 | US97136...) Show SMILES CC1(C)OC(=O)c2ccc(cc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C26H26FN3O3/c1-26(2)21-11-14(6-8-20(21)25(32)33-26)15-3-4-16(22(27)12-15)9-19(13-28)30-24(31)23-17-5-7-18(10-17)29-23/h3-4,6,8,11-12,17-19,23,29H,5,7,9-10H2,1-2H3,(H,30,31)/t17-,18+,19-,23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 6007270). The substrate Gly-Arg-AMC was from Biotrend (Prod....				US Patent US9713606 (2017) BindingDB Entry DOI: 10.7270/Q21G0P8M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201016 (US9540373, 5 | US9879026, Example 5 | USRE47636, E...) Show SMILES CN1C(=O)C2(CCN(C)CC2)c2cc(ccc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C30H34FN5O2/c1-35-11-9-30(10-12-35)24-15-18(6-8-26(24)36(2)29(30)38)19-3-4-20(25(31)16-19)13-23(17-32)34-28(37)27-21-5-7-22(14-21)33-27/h3-4,6,8,15-16,21-23,27,33H,5,7,9-14H2,1-2H3,(H,34,37)/t21-,22+,23-,27-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				US Patent US9540373 (2017) BindingDB Entry DOI: 10.7270/Q2NK3C6R
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201021 (US9540373, 10 | US9879026, Example 10 | USRE47636,...) Show SMILES CN1CCC2(C1)OC(=O)c1ccc(cc21)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C28H29FN4O3/c1-33-9-8-28(15-33)23-12-16(5-7-22(23)27(35)36-28)17-2-3-18(24(29)13-17)10-21(14-30)32-26(34)25-19-4-6-20(11-19)31-25/h2-3,5,7,12-13,19-21,25,31H,4,6,8-11,15H2,1H3,(H,32,34)/t19-,20+,21-,25-,28?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				US Patent US9540373 (2017) BindingDB Entry DOI: 10.7270/Q2NK3C6R
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201024 (US9540373, 13 | US9879026, Example 13 | USRE47636,...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2COC3(CCNCC3)c2c1 |r| Show InChI InChI=1S/C28H31FN4O2/c29-25-14-18(17-2-4-21-16-35-28(24(21)13-17)7-9-31-10-8-28)1-3-19(25)11-23(15-30)33-27(34)26-20-5-6-22(12-20)32-26/h1-4,13-14,20,22-23,26,31-32H,5-12,16H2,(H,33,34)/t20-,22+,23-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				US Patent US9540373 (2017) BindingDB Entry DOI: 10.7270/Q2NK3C6R
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201013 (US9540373, 2 | US9879026, Example 2 | USRE47636, E...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2CCC3(CCNCC3)c2c1 |r| Show InChI InChI=1S/C29H33FN4O/c30-26-16-20(19-2-1-18-7-8-29(25(18)15-19)9-11-32-12-10-29)3-4-21(26)13-24(17-31)34-28(35)27-22-5-6-23(14-22)33-27/h1-4,15-16,22-24,27,32-33H,5-14H2,(H,34,35)/t22-,23+,24-,27-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				US Patent US9540373 (2017) BindingDB Entry DOI: 10.7270/Q2NK3C6R
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201013 (US9540373, 2 | US9879026, Example 2 | USRE47636, E...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2CCC3(CCNCC3)c2c1 |r| Show InChI InChI=1S/C29H33FN4O/c30-26-16-20(19-2-1-18-7-8-29(25(18)15-19)9-11-32-12-10-29)3-4-21(26)13-24(17-31)34-28(35)27-22-5-6-23(14-22)33-27/h1-4,15-16,22-24,27,32-33H,5-14H2,(H,34,35)/t22-,23+,24-,27-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...				US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201016 (US9540373, 5 | US9879026, Example 5 | USRE47636, E...) Show SMILES CN1C(=O)C2(CCN(C)CC2)c2cc(ccc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C30H34FN5O2/c1-35-11-9-30(10-12-35)24-15-18(6-8-26(24)36(2)29(30)38)19-3-4-20(25(31)16-19)13-23(17-32)34-28(37)27-21-5-7-22(14-21)33-27/h3-4,6,8,15-16,21-23,27,33H,5,7,9-14H2,1-2H3,(H,34,37)/t21-,22+,23-,27-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...				US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201021 (US9540373, 10 | US9879026, Example 10 | USRE47636,...) Show SMILES CN1CCC2(C1)OC(=O)c1ccc(cc21)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C28H29FN4O3/c1-33-9-8-28(15-33)23-12-16(5-7-22(23)27(35)36-28)17-2-3-18(24(29)13-17)10-21(14-30)32-26(34)25-19-4-6-20(11-19)31-25/h2-3,5,7,12-13,19-21,25,31H,4,6,8-11,15H2,1H3,(H,32,34)/t19-,20+,21-,25-,28?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...				US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201024 (US9540373, 13 | US9879026, Example 13 | USRE47636,...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2COC3(CCNCC3)c2c1 |r| Show InChI InChI=1S/C28H31FN4O2/c29-25-14-18(17-2-4-21-16-35-28(24(21)13-17)7-9-31-10-8-28)1-3-19(25)11-23(15-30)33-27(34)26-20-5-6-22(12-20)32-26/h1-4,13-14,20,22-23,26,31-32H,5-12,16H2,(H,33,34)/t20-,22+,23-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Assay conditions: The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in...				US Patent US9879026 (2018) BindingDB Entry DOI: 10.7270/Q2K0768M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM150482 (US10238633, Example 156 | US8987249, 156 | US97136...) Show SMILES CC1(C)OC(=O)c2ccc(cc12)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C26H26FN3O3/c1-26(2)21-11-14(6-8-20(21)25(32)33-26)15-3-4-16(22(27)12-15)9-19(13-28)30-24(31)23-17-5-7-18(10-17)29-23/h3-4,6,8,11-12,17-19,23,29H,5,7,9-10H2,1-2H3,(H,30,31)/t17-,18+,19-,23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q22R3TZF
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201021 (US9540373, 10 | US9879026, Example 10 | USRE47636,...) Show SMILES CN1CCC2(C1)OC(=O)c1ccc(cc21)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C28H29FN4O3/c1-33-9-8-28(15-33)23-12-16(5-7-22(23)27(35)36-28)17-2-3-18(24(29)13-17)10-21(14-30)32-26(34)25-19-4-6-20(11-19)31-25/h2-3,5,7,12-13,19-21,25,31H,4,6,8-11,15H2,1H3,(H,32,34)/t19-,20+,21-,25-,28?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...				US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201019 (US9540373, 8 | US9879026, Example 8 | USRE47636, E...) Show SMILES CN1CCC2(CC1)OC(=O)c1ccc(cc21)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C29H31FN4O3/c1-34-10-8-29(9-11-34)24-14-17(5-7-23(24)28(36)37-29)18-2-3-19(25(30)15-18)12-22(16-31)33-27(35)26-20-4-6-21(13-20)32-26/h2-3,5,7,14-15,20-22,26,32H,4,6,8-13H2,1H3,(H,33,35)/t20-,21+,22-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...				US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201022 (US9540373, 11 | US9879026, Example 11 | USRE47636,...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2C(=O)OC3(CNC3)c2c1 |r| Show InChI InChI=1S/C26H25FN4O3/c27-22-10-15(14-4-6-20-21(9-14)26(12-29-13-26)34-25(20)33)1-2-16(22)7-19(11-28)31-24(32)23-17-3-5-18(8-17)30-23/h1-2,4,6,9-10,17-19,23,29-30H,3,5,7-8,12-13H2,(H,31,32)/t17-,18+,19-,23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 10 6007270). The substrate Gly-Arg-AMC was from Biotrend (Pr...				US Patent USRE47636 (2019) BindingDB Entry DOI: 10.7270/Q27D2XG4
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM150329 (US10238633, Example 3 | US8987249, 3 | US9713606, ...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2C(=O)OCc2c1 |r| Show InChI InChI=1S/C24H22FN3O3/c25-21-10-14(13-4-6-20-17(7-13)12-31-24(20)30)1-2-15(21)8-19(11-26)28-23(29)22-16-3-5-18(9-16)27-22/h1-2,4,6-7,10,16,18-19,22,27H,3,5,8-9,12H2,(H,28,29)/t16-,18+,19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 ug/ml, respectively), and then activated by mixing in a 1:2 ratio with a Cys...				US Patent US8987249 (2015) BindingDB Entry DOI: 10.7270/Q2KP80WG
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM150329 (US10238633, Example 3 | US8987249, 3 | US9713606, ...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2C(=O)OCc2c1 |r| Show InChI InChI=1S/C24H22FN3O3/c25-21-10-14(13-4-6-20-17(7-13)12-31-24(20)30)1-2-15(21)8-19(11-26)28-23(29)22-16-3-5-18(9-16)27-22/h1-2,4,6-7,10,16,18-19,22,27H,3,5,8-9,12H2,(H,28,29)/t16-,18+,19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	6.0	25
Boehringer Ingelheim International GmbH US Patent					Assay Description Materials: Microtiterplates (Optiplate-384 F) were purchased from PerkinElmer (Prod. No. 6007270). The substrate Gly-Arg-AMC was from Biotrend (Prod....				US Patent US9713606 (2017) BindingDB Entry DOI: 10.7270/Q21G0P8M
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM150329 (US10238633, Example 3 | US8987249, 3 | US9713606, ...) Show SMILES Fc1cc(ccc1C[C@H](NC(=O)[C@H]1N[C@@H]2CC[C@H]1C2)C#N)-c1ccc2C(=O)OCc2c1 |r| Show InChI InChI=1S/C24H22FN3O3/c25-21-10-14(13-4-6-20-17(7-13)12-31-24(20)30)1-2-15(21)8-19(11-26)28-23(29)22-16-3-5-18(9-16)27-22/h1-2,4,6-7,10,16,18-19,22,27H,3,5,8-9,12H2,(H,28,29)/t16-,18+,19-,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Bayer HealthCare Pharmaceuticals Corporation					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q22R3TZF
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 1 (Homo sapiens (Human))	BDBM201019 (US9540373, 8 | US9879026, Example 8 | USRE47636, E...) Show SMILES CN1CCC2(CC1)OC(=O)c1ccc(cc21)-c1ccc(C[C@H](NC(=O)[C@H]2N[C@@H]3CC[C@H]2C3)C#N)c(F)c1 |r| Show InChI InChI=1S/C29H31FN4O3/c1-34-10-8-29(9-11-34)24-14-17(5-7-23(24)28(36)37-29)18-2-3-19(25(30)15-18)12-22(16-31)33-27(35)26-20-4-6-21(13-20)32-26/h2-3,5,7,14-15,20-22,26,32H,4,6,8-13H2,1H3,(H,33,35)/t20-,21+,22-,26-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The recombinant human DPPI was diluted in TAGZyme buffer to 1 U/ml (38.1 μg/ml, respectively), and then activated by mixing in a 1:2 ratio with ...				US Patent US9540373 (2017) BindingDB Entry DOI: 10.7270/Q2NK3C6R
					More data for this Ligand-Target Pair

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