Compile Data Set for Download or QSAR

Found 217 hits of ic50 data for polymerid = 6985   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50019283 (CHEMBL3289121) Show SMILES CCOc1ccccc1-c1nc2ccccc2c(=O)[nH]1 Show InChI InChI=1S/C16H14N2O2/c1-2-20-14-10-6-4-8-12(14)15-17-13-9-5-3-7-11(13)16(19)18-15/h3-10H,2H2,1H3,(H,17,18,19)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Compound was tested for TXA2 receptor antagonism by measuring its ability to inhibit contraction of rat aorta induced by the stable TXA2 agonist U-46...				Eur J Med Chem 139: 849-864 (2017) Article DOI: 10.1016/j.ejmech.2017.08.052 BindingDB Entry DOI: 10.7270/Q20P12HF
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50019166 (CHEMBL336718) Show SMILES COc1ccc(cc1)-c1nc(O)c2ccccc2n1 Show InChI InChI=1S/C15H12N2O2/c1-19-11-8-6-10(7-9-11)14-16-13-5-3-2-4-12(13)15(18)17-14/h2-9H,1H3,(H,16,17,18)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Compound was tested for TXA2 receptor antagonism by measuring its ability to inhibit contraction of rat aorta induced by the stable TXA2 agonist U-46...				Eur J Med Chem 139: 849-864 (2017) Article DOI: 10.1016/j.ejmech.2017.08.052 BindingDB Entry DOI: 10.7270/Q20P12HF
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50233861 (CHEMBL4084524) Show SMILES Cc1ncc(n1CCOC(=O)c1cc(F)c(F)cc1Cl)[N+]([O-])=O Show InChI InChI=1S/C13H10ClF2N3O4/c1-7-17-6-12(19(21)22)18(7)2-3-23-13(20)8-4-10(15)11(16)5-9(8)14/h4-6H,2-3H2,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...				Eur J Med Chem 125: 1289-1299 (2017) Article DOI: 10.1016/j.ejmech.2016.11.031 BindingDB Entry DOI: 10.7270/Q2125VXZ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50277802 (CHEMBL4172107) Show SMILES Oc1c(Cl)cc(Cl)cc1S(=O)(=O)Nc1cccc2ncccc12 Show InChI InChI=1S/C15H10Cl2N2O3S/c16-9-7-11(17)15(20)14(8-9)23(21,22)19-13-5-1-4-12-10(13)3-2-6-18-12/h1-8,19-20H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Antagonistic activity for inhibition of histamine H2 receptor from anesthetized rats				Eur J Med Chem 139: 849-864 (2017) Article DOI: 10.1016/j.ejmech.2017.08.052 BindingDB Entry DOI: 10.7270/Q20P12HF
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50008884 (CHEMBL3237329) Show SMILES Oc1ccc(C(c2c[nH]c3ccc(Br)cc23)c2c[nH]c3ccc(Br)cc23)c(O)c1 Show InChI InChI=1S/C23H16Br2N2O2/c24-12-1-5-20-16(7-12)18(10-26-20)23(15-4-3-14(28)9-22(15)29)19-11-27-21-6-2-13(25)8-17(19)21/h1-11,23,26-29H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometry				Bioorg Med Chem Lett 24: 1825-9 (2014) Article DOI: 10.1016/j.bmcl.2014.02.015 BindingDB Entry DOI: 10.7270/Q2R78GRJ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50019285 (CHEMBL3289122) Show SMILES COc1ccc(O)c(c1)-c1nc2ccccc2c(=O)[nH]1 Show InChI InChI=1S/C15H12N2O3/c1-20-9-6-7-13(18)11(8-9)14-16-12-5-3-2-4-10(12)15(19)17-14/h2-8,18H,1H3,(H,16,17,19)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...				Eur J Med Chem 139: 849-864 (2017) Article DOI: 10.1016/j.ejmech.2017.08.052 BindingDB Entry DOI: 10.7270/Q20P12HF
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50008901 (CHEMBL2430239) Show SMILES Oc1ccc(cc1)C(c1c[nH]c2ccc(Br)cc12)c1c[nH]c2ccc(Br)cc12 Show InChI InChI=1S/C23H16Br2N2O/c24-14-3-7-21-17(9-14)19(11-26-21)23(13-1-5-16(28)6-2-13)20-12-27-22-8-4-15(25)10-18(20)22/h1-12,23,26-28H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometry				Bioorg Med Chem Lett 24: 1825-9 (2014) Article DOI: 10.1016/j.bmcl.2014.02.015 BindingDB Entry DOI: 10.7270/Q2R78GRJ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50233856 (CHEMBL4092265) Show SMILES Cc1ncc(n1CCOC(=O)c1cc2ccccc2[nH]1)[N+]([O-])=O Show InChI InChI=1S/C15H14N4O4/c1-10-16-9-14(19(21)22)18(10)6-7-23-15(20)13-8-11-4-2-3-5-12(11)17-13/h2-5,8-9,17H,6-7H2,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...				Eur J Med Chem 125: 1289-1299 (2017) Article DOI: 10.1016/j.ejmech.2016.11.031 BindingDB Entry DOI: 10.7270/Q2125VXZ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50277979 (CHEMBL4167683) Show SMILES Clc1ccc(c(Cl)c1)S(=O)(=O)Nc1cccc2ncccc12 Show InChI InChI=1S/C15H10Cl2N2O2S/c16-10-6-7-15(12(17)9-10)22(20,21)19-14-5-1-4-13-11(14)3-2-8-18-13/h1-9,19H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...				Eur J Med Chem 139: 849-864 (2017) Article DOI: 10.1016/j.ejmech.2017.08.052 BindingDB Entry DOI: 10.7270/Q20P12HF
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50092444 (CHEMBL3586121) Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)-c1nnc(o1)-c1ccccc1O Show InChI InChI=1S/C23H18N4O2/c1-13-11-18-19(12-14(13)2)25-21(24-18)15-7-9-16(10-8-15)22-26-27-23(29-22)17-5-3-4-6-20(17)28/h3-12,28H,1-2H3,(H,24,25)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...				Bioorg Med Chem 24: 1909-18 (2016) Article DOI: 10.1016/j.bmc.2016.03.020 BindingDB Entry DOI: 10.7270/Q28917RB
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50160569 (CHEMBL3785671) Show SMILES Clc1ccc(Nc2nnc(s2)-c2ccccc2Cl)cc1Cl Show InChI InChI=1S/C14H8Cl3N3S/c15-10-4-2-1-3-9(10)13-19-20-14(21-13)18-8-5-6-11(16)12(17)7-8/h1-7H,(H,18,20)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...				Bioorg Med Chem 24: 1909-18 (2016) Article DOI: 10.1016/j.bmc.2016.03.020 BindingDB Entry DOI: 10.7270/Q28917RB
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM193670 (N,N'-(disulfanediylbis(2,1-phenylene))bis(2,4,...) Show SMILES Clc1cc(Cl)c(cc1Cl)S(=O)(=O)Nc1ccccc1SSc1ccccc1NS(=O)(=O)c1cc(Cl)c(Cl)cc1Cl Show InChI InChI=1S/C24H14Cl6N2O4S4/c25-13-9-17(29)23(11-15(13)27)39(33,34)31-19-5-1-3-7-21(19)37-38-22-8-4-2-6-20(22)32-40(35,36)24-12-16(28)14(26)10-18(24)30/h1-12,31-32H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Teknologi MARA					Assay Description β-glucuronidase activity was determined by measuring absorbance at 405 nm of p-nitrophenol formed substrate by spectrophotometric method. 250 µL...				Bioorg Chem 68: 15-22 (2016) Article DOI: 10.1016/j.bioorg.2016.07.002 BindingDB Entry DOI: 10.7270/Q2542MCP
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50484065 (CHEMBL1808311) Show SMILES Oc1cc(O)c(cc1O)-c1nc2ccccc2s1 Show InChI InChI=1S/C13H9NO3S/c15-9-6-11(17)10(16)5-7(9)13-14-8-3-1-2-4-12(8)18-13/h1-6,15-17H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta glucuronidase assessed as p-nitrophenol formation after 30 mins by spectrophotometric method				Bioorg Med Chem 19: 4286-94 (2011) Article DOI: 10.1016/j.bmc.2011.05.052 BindingDB Entry DOI: 10.7270/Q2FB55SC
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50008904 (CHEMBL3237336) Show SMILES COc1cccc(C(c2c[nH]c3ccc(cc23)C#N)c2c[nH]c3ccc(cc23)C#N)c1O Show InChI InChI=1S/C26H18N4O2/c1-32-24-4-2-3-17(26(24)31)25(20-13-29-22-7-5-15(11-27)9-18(20)22)21-14-30-23-8-6-16(12-28)10-19(21)23/h2-10,13-14,25,29-31H,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometry				Bioorg Med Chem Lett 24: 1825-9 (2014) Article DOI: 10.1016/j.bmcl.2014.02.015 BindingDB Entry DOI: 10.7270/Q2R78GRJ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50019170 (2-(3'-Hydroxy-4'-methoxyphenyl)quinazolin-...) Show SMILES COc1ccc(cc1O)-c1nc2ccccc2c(=O)[nH]1 Show InChI InChI=1S/C15H12N2O3/c1-20-13-7-6-9(8-12(13)18)14-16-11-5-3-2-4-10(11)15(19)17-14/h2-8,18H,1H3,(H,16,17,19)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Antagonistic activity for inhibition of histamine H2 receptor from anesthetized rats				Eur J Med Chem 139: 849-864 (2017) Article DOI: 10.1016/j.ejmech.2017.08.052 BindingDB Entry DOI: 10.7270/Q20P12HF
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50008903 (CHEMBL3237335) Show SMILES Oc1ccc(Cl)cc1C(c1c[nH]c2ccc(Br)cc12)c1c[nH]c2ccc(Br)cc12 Show InChI InChI=1S/C23H15Br2ClN2O/c24-12-1-4-20-15(7-12)18(10-27-20)23(17-9-14(26)3-6-22(17)29)19-11-28-21-5-2-13(25)8-16(19)21/h1-11,23,27-29H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometry				Bioorg Med Chem Lett 24: 1825-9 (2014) Article DOI: 10.1016/j.bmcl.2014.02.015 BindingDB Entry DOI: 10.7270/Q2R78GRJ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM222109 ((E)-4-(3-Nitrophenyl)-2-(2-(pyren-1-ylmethylene)hy...) Show SMILES [O-][N+](=O)c1cccc(c1)-c1csc(N\N=C\c2ccc3ccc4cccc5ccc2c3c45)n1 Show InChI InChI=1S/C26H16N4O2S/c31-30(32)21-6-2-5-19(13-21)23-15-33-26(28-23)29-27-14-20-10-9-18-8-7-16-3-1-4-17-11-12-22(20)25(18)24(16)17/h1-15H,(H,28,29)/b27-14+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi					Assay Description β-Glucuronidase inhibitory activity was measured by quantifying the absorbance of para-nitrophenol which was formed from the substrate by the sp...				Bioorg Chem 70: 199-209 (2017) Article DOI: 10.1016/j.bioorg.2016.12.011 BindingDB Entry DOI: 10.7270/Q2VH5MQ9
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM222114 ((E)-2-(2-(2-(Pyren-1-ylmethylene)hydrazinyl)thiazo...) Show SMILES Oc1ccccc1-c1csc(N\N=C\c2ccc3ccc4cccc5ccc2c3c45)n1 Show InChI InChI=1S/C26H17N3OS/c30-23-7-2-1-6-21(23)22-15-31-26(28-22)29-27-14-19-11-10-18-9-8-16-4-3-5-17-12-13-20(19)25(18)24(16)17/h1-15,30H,(H,28,29)/b27-14+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi					Assay Description β-Glucuronidase inhibitory activity was measured by quantifying the absorbance of para-nitrophenol which was formed from the substrate by the sp...				Bioorg Chem 70: 199-209 (2017) Article DOI: 10.1016/j.bioorg.2016.12.011 BindingDB Entry DOI: 10.7270/Q2VH5MQ9
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM193667 (N,N'-(disulfanediylbis(2,1-phenylene))bis(2,4-...) Show SMILES [O-][N+](=O)c1ccc(c(c1)[N+]([O-])=O)S(=O)(=O)Nc1ccccc1SSc1ccccc1NS(=O)(=O)c1ccc(cc1[N+]([O-])=O)[N+]([O-])=O Show InChI InChI=1S/C24H16N6O12S4/c31-27(32)15-9-11-23(19(13-15)29(35)36)45(39,40)25-17-5-1-3-7-21(17)43-44-22-8-4-2-6-18(22)26-46(41,42)24-12-10-16(28(33)34)14-20(24)30(37)38/h1-14,25-26H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Teknologi MARA					Assay Description β-glucuronidase activity was determined by measuring absorbance at 405 nm of p-nitrophenol formed substrate by spectrophotometric method. 250 µL...				Bioorg Chem 68: 15-22 (2016) Article DOI: 10.1016/j.bioorg.2016.07.002 BindingDB Entry DOI: 10.7270/Q2542MCP
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50233864 (CHEMBL4067308) Show SMILES Cc1ncc(n1CCOC(=O)c1ccc(Cl)c(Cl)c1)[N+]([O-])=O Show InChI InChI=1S/C13H11Cl2N3O4/c1-8-16-7-12(18(20)21)17(8)4-5-22-13(19)9-2-3-10(14)11(15)6-9/h2-3,6-7H,4-5H2,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...				Eur J Med Chem 125: 1289-1299 (2017) Article DOI: 10.1016/j.ejmech.2016.11.031 BindingDB Entry DOI: 10.7270/Q2125VXZ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM222116 ((E)-2-(2-(Pyren-1-ylmethylene)hydrazinyl)thiazol-4...) Show SMILES O=C1CSC(N\N=C\c2ccc3ccc4cccc5ccc2c3c45)=N1 |c:27| Show InChI InChI=1S/C20H13N3OS/c24-17-11-25-20(22-17)23-21-10-15-7-6-14-5-4-12-2-1-3-13-8-9-16(15)19(14)18(12)13/h1-10H,11H2,(H,22,23,24)/b21-10+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi					Assay Description β-Glucuronidase inhibitory activity was measured by quantifying the absorbance of para-nitrophenol which was formed from the substrate by the sp...				Bioorg Chem 70: 199-209 (2017) Article DOI: 10.1016/j.bioorg.2016.12.011 BindingDB Entry DOI: 10.7270/Q2VH5MQ9
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50160575 (CHEMBL3786740) Show SMILES COc1ccc(cc1)-c1nnc(Nc2ccc(Cl)c(Cl)c2)s1 Show InChI InChI=1S/C15H11Cl2N3OS/c1-21-11-5-2-9(3-6-11)14-19-20-15(22-14)18-10-4-7-12(16)13(17)8-10/h2-8H,1H3,(H,18,20)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...				Bioorg Med Chem 24: 1909-18 (2016) Article DOI: 10.1016/j.bmc.2016.03.020 BindingDB Entry DOI: 10.7270/Q28917RB
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50484063 (CHEMBL1650632) Show SMILES Oc1ccccc1-c1nc2ccccc2s1 Show InChI InChI=1S/C13H9NOS/c15-11-7-3-1-5-9(11)13-14-10-6-2-4-8-12(10)16-13/h1-8,15H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta glucuronidase assessed as p-nitrophenol formation after 30 mins by spectrophotometric method				Bioorg Med Chem 19: 4286-94 (2011) Article DOI: 10.1016/j.bmc.2011.05.052 BindingDB Entry DOI: 10.7270/Q2FB55SC
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50008905 (CHEMBL3237340) Show SMILES COc1cc(ccc1O)C(c1c[nH]c2ccc(cc12)C#N)c1c[nH]c2ccc(cc12)C#N Show InChI InChI=1S/C26H18N4O2/c1-32-25-10-17(4-7-24(25)31)26(20-13-29-22-5-2-15(11-27)8-18(20)22)21-14-30-23-6-3-16(12-28)9-19(21)23/h2-10,13-14,26,29-31H,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate after 30 mins by spectrophotometry				Bioorg Med Chem Lett 24: 1825-9 (2014) Article DOI: 10.1016/j.bmcl.2014.02.015 BindingDB Entry DOI: 10.7270/Q2R78GRJ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM152561 (2-(4,6-dichloro-1H-benzo[d]imidazol-2-yl)phenol (1...) Show SMILES Oc1ccccc1-c1nc2c(Cl)cc(Cl)cc2[nH]1 Show InChI InChI=1S/C13H8Cl2N2O/c14-7-5-9(15)12-10(6-7)16-13(17-12)8-3-1-2-4-11(8)18/h1-6,18H,(H,16,17)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.48E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Teknologi MARA (UiTM)					Assay Description β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...				Bioorg Chem 61: 36-44 (2015) Article DOI: 10.1016/j.bioorg.2015.05.010 BindingDB Entry DOI: 10.7270/Q2HH6HTP
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50277980 (CHEMBL4165343) Show SMILES Clc1ccc(Cl)c(c1)S(=O)(=O)Nc1cccc2ncccc12 Show InChI InChI=1S/C15H10Cl2N2O2S/c16-10-6-7-12(17)15(9-10)22(20,21)19-14-5-1-4-13-11(14)3-2-8-18-13/h1-9,19H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...				Eur J Med Chem 139: 849-864 (2017) Article DOI: 10.1016/j.ejmech.2017.08.052 BindingDB Entry DOI: 10.7270/Q20P12HF
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50160567 (CHEMBL3787430) Show SMILES Oc1cccc(\C=N/c2nc(cs2)-c2ccccc2)c1O Show InChI InChI=1S/C16H12N2O2S/c19-14-8-4-7-12(15(14)20)9-17-16-18-13(10-21-16)11-5-2-1-3-6-11/h1-10,19-20H/b17-9-	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...				Bioorg Med Chem 24: 1909-18 (2016) Article DOI: 10.1016/j.bmc.2016.03.020 BindingDB Entry DOI: 10.7270/Q28917RB
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM222103 ((E)-2-(Pyren-1-ylmethylene)hydrazine-1-carbothioam...) Show SMILES NC(=S)N\N=C\c1ccc2ccc3cccc4ccc1c2c34 Show InChI InChI=1S/C18H13N3S/c19-18(22)21-20-10-14-7-6-13-5-4-11-2-1-3-12-8-9-15(14)17(13)16(11)12/h1-10H,(H3,19,21,22)/b20-10+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi					Assay Description β-Glucuronidase inhibitory activity was measured by quantifying the absorbance of para-nitrophenol which was formed from the substrate by the sp...				Bioorg Chem 70: 199-209 (2017) Article DOI: 10.1016/j.bioorg.2016.12.011 BindingDB Entry DOI: 10.7270/Q2VH5MQ9
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM45890 (2,5-bis(chloranyl)-N-quinolin-3-yl-benzenesulfonam...) Show SMILES Clc1ccc(Cl)c(c1)S(=O)(=O)Nc1cnc2ccccc2c1 Show InChI InChI=1S/C15H10Cl2N2O2S/c16-11-5-6-13(17)15(8-11)22(20,21)19-12-7-10-3-1-2-4-14(10)18-9-12/h1-9,19H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Antagonistic activity by inhibition histamine H2 receptor from rats.				Eur J Med Chem 139: 849-864 (2017) Article DOI: 10.1016/j.ejmech.2017.08.052 BindingDB Entry DOI: 10.7270/Q20P12HF
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50277965 (CHEMBL3969674) Show SMILES Clc1ccc(c(Cl)c1)S(=O)(=O)Nc1cccc2cccnc12 Show InChI InChI=1S/C15H10Cl2N2O2S/c16-11-6-7-14(12(17)9-11)22(20,21)19-13-5-1-3-10-4-2-8-18-15(10)13/h1-9,19H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Compound was tested for TXA2 receptor antagonism by measuring its ability to inhibit contraction of rat aorta induced by the stable TXA2 agonist U-46...				Eur J Med Chem 139: 849-864 (2017) Article DOI: 10.1016/j.ejmech.2017.08.052 BindingDB Entry DOI: 10.7270/Q20P12HF
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM222112 ((E)-4-(3,4-Dichlorophenyl)-2-(2-(pyren-1-ylmethyle...) Show SMILES Clc1ccc(cc1Cl)-c1csc(N\N=C\c2ccc3ccc4cccc5ccc2c3c45)n1 Show InChI InChI=1S/C26H15Cl2N3S/c27-21-11-9-18(12-22(21)28)23-14-32-26(30-23)31-29-13-19-7-6-17-5-4-15-2-1-3-16-8-10-20(19)25(17)24(15)16/h1-14H,(H,30,31)/b29-13+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi					Assay Description β-Glucuronidase inhibitory activity was measured by quantifying the absorbance of para-nitrophenol which was formed from the substrate by the sp...				Bioorg Chem 70: 199-209 (2017) Article DOI: 10.1016/j.bioorg.2016.12.011 BindingDB Entry DOI: 10.7270/Q2VH5MQ9
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50233876 (CHEMBL4096282) Show SMILES Cc1ncc(n1CCOC(=O)c1cc(Cl)ccc1Cl)[N+]([O-])=O Show InChI InChI=1S/C13H11Cl2N3O4/c1-8-16-7-12(18(20)21)17(8)4-5-22-13(19)10-6-9(14)2-3-11(10)15/h2-3,6-7H,4-5H2,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...				Eur J Med Chem 125: 1289-1299 (2017) Article DOI: 10.1016/j.ejmech.2016.11.031 BindingDB Entry DOI: 10.7270/Q2125VXZ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM193657 (N,N'-(disulfanediylbis(2,1-phenylene))bis(2-fl...) Show SMILES Fc1ccccc1S(=O)(=O)Nc1ccccc1SSc1ccccc1NS(=O)(=O)c1ccccc1F Show InChI InChI=1S/C24H18F2N2O4S4/c25-17-9-1-7-15-23(17)35(29,30)27-19-11-3-5-13-21(19)33-34-22-14-6-4-12-20(22)28-36(31,32)24-16-8-2-10-18(24)26/h1-16,27-28H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Teknologi MARA					Assay Description β-glucuronidase activity was determined by measuring absorbance at 405 nm of p-nitrophenol formed substrate by spectrophotometric method. 250 µL...				Bioorg Chem 68: 15-22 (2016) Article DOI: 10.1016/j.bioorg.2016.07.002 BindingDB Entry DOI: 10.7270/Q2542MCP
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50160574 (CHEMBL3785548) Show SMILES Clc1ccc(Nc2nnc(s2)-c2ccccc2)cc1Cl Show InChI InChI=1S/C14H9Cl2N3S/c15-11-7-6-10(8-12(11)16)17-14-19-18-13(20-14)9-4-2-1-3-5-9/h1-8H,(H,17,19)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...				Bioorg Med Chem 24: 1909-18 (2016) Article DOI: 10.1016/j.bmc.2016.03.020 BindingDB Entry DOI: 10.7270/Q28917RB
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50233869 (CHEMBL4097214) Show SMILES Cc1ncc(n1CCOC(=O)c1ccc(F)cc1Br)[N+]([O-])=O Show InChI InChI=1S/C13H11BrFN3O4/c1-8-16-7-12(18(20)21)17(8)4-5-22-13(19)10-3-2-9(15)6-11(10)14/h2-3,6-7H,4-5H2,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...				Eur J Med Chem 125: 1289-1299 (2017) Article DOI: 10.1016/j.ejmech.2016.11.031 BindingDB Entry DOI: 10.7270/Q2125VXZ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50233873 (CHEMBL4071944) Show SMILES Clc1ccc(cc1Cl)-c1nc2ccccc2[nH]1 Show InChI InChI=1S/C13H8Cl2N2/c14-9-6-5-8(7-10(9)15)13-16-11-3-1-2-4-12(11)17-13/h1-7H,(H,16,17)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...				Eur J Med Chem 125: 1289-1299 (2017) Article DOI: 10.1016/j.ejmech.2016.11.031 BindingDB Entry DOI: 10.7270/Q2125VXZ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50277963 (CHEMBL4171503) Show SMILES [O-][N+](=O)c1ccccc1S(=O)(=O)Oc1cccc2cccnc12 Show InChI InChI=1S/C15H10N2O5S/c18-17(19)12-7-1-2-9-14(12)23(20,21)22-13-8-3-5-11-6-4-10-16-15(11)13/h1-10H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Compound was tested for TXA2 receptor antagonism by measuring its ability to inhibit contraction of rat aorta induced by the stable TXA2 agonist U-46...				Eur J Med Chem 139: 849-864 (2017) Article DOI: 10.1016/j.ejmech.2017.08.052 BindingDB Entry DOI: 10.7270/Q20P12HF
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50046957 (CHEBI:66441 | SCOPARIC ACID A) Show SMILES [H][C@@]12[C@@H](CC(=C)[C@@H](CC\C(C)=C\CO)[C@@]1(C)CCC[C@@]2(C)C(O)=O)OC(=O)c1ccccc1 |r| Show InChI InChI=1S/C27H36O5/c1-18(13-16-28)11-12-21-19(2)17-22(32-24(29)20-9-6-5-7-10-20)23-26(21,3)14-8-15-27(23,4)25(30)31/h5-7,9-10,13,21-23,28H,2,8,11-12,14-17H2,1,3-4H3,(H,30,31)/b18-13+/t21-,22-,23-,26-,27-/m1/s1	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Toyama Medical and Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of bovine beta-glucuronidase				J Nat Prod 55: 1748-55 (1992) Article DOI: 10.1021/np50090a005 BindingDB Entry DOI: 10.7270/Q2CJ8H9T
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50129852 (CHEMBL3628915) Show SMILES COc1ccc(\C=N\NC(=O)c2ccc(cc2)-c2nnc(o2)-c2ccccc2O)cc1O Show InChI InChI=1S/C23H18N4O5/c1-31-20-11-6-14(12-19(20)29)13-24-25-21(30)15-7-9-16(10-8-15)22-26-27-23(32-22)17-4-2-3-5-18(17)28/h2-13,28-29H,1H3,(H,25,30)/b24-13+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Teknologi MARA (UiTM) Curated by ChEMBL					Assay Description Inhibition of bovine liver beta-glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate assessed as p-nitrophenol formation after 30 mins b...				Bioorg Med Chem 23: 7394-404 (2015) Article DOI: 10.1016/j.bmc.2015.10.037 BindingDB Entry DOI: 10.7270/Q2765H56
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50160570 (CHEMBL3787019) Show SMILES Clc1ccc(Nc2nnc(s2)-c2ccc(Br)cc2)cc1Cl Show InChI InChI=1S/C14H8BrCl2N3S/c15-9-3-1-8(2-4-9)13-19-20-14(21-13)18-10-5-6-11(16)12(17)7-10/h1-7H,(H,18,20)	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine beta-glucuronidase assessed as p-nitrophenol formation preincubated for 30 mins followed by addition of p-nitrophenyl-beta-D-glu...				Bioorg Med Chem 24: 1909-18 (2016) Article DOI: 10.1016/j.bmc.2016.03.020 BindingDB Entry DOI: 10.7270/Q28917RB
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50233868 (CHEMBL4100978) Show SMILES Cc1ncc(n1CCOC(=O)c1ccc(c(C)c1)[N+]([O-])=O)[N+]([O-])=O Show InChI InChI=1S/C14H14N4O6/c1-9-7-11(3-4-12(9)17(20)21)14(19)24-6-5-16-10(2)15-8-13(16)18(22)23/h3-4,7-8H,5-6H2,1-2H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...				Eur J Med Chem 125: 1289-1299 (2017) Article DOI: 10.1016/j.ejmech.2016.11.031 BindingDB Entry DOI: 10.7270/Q2125VXZ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50233863 (CHEMBL4078230) Show SMILES Cc1ncc(n1CCOC(=O)c1cccc(F)c1)[N+]([O-])=O Show InChI InChI=1S/C13H12FN3O4/c1-9-15-8-12(17(19)20)16(9)5-6-21-13(18)10-3-2-4-11(14)7-10/h2-4,7-8H,5-6H2,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...				Eur J Med Chem 125: 1289-1299 (2017) Article DOI: 10.1016/j.ejmech.2016.11.031 BindingDB Entry DOI: 10.7270/Q2125VXZ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50277804 (CHEMBL4163673) Show SMILES [O-][N+](=O)c1ccccc1S(=O)(=O)Nc1cnc2ccccc2c1 Show InChI InChI=1S/C15H11N3O4S/c19-18(20)14-7-3-4-8-15(14)23(21,22)17-12-9-11-5-1-2-6-13(11)16-10-12/h1-10,17H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Antagonistic activity for inhibition of histamine H2 receptor from anesthetized rats				Eur J Med Chem 139: 849-864 (2017) Article DOI: 10.1016/j.ejmech.2017.08.052 BindingDB Entry DOI: 10.7270/Q20P12HF
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM193654 (N,N'-(disulfanediylbis(2,1-phenylene))bis(2-ch...) Show SMILES Clc1ccccc1S(=O)(=O)Nc1ccccc1SSc1ccccc1NS(=O)(=O)c1ccccc1Cl Show InChI InChI=1S/C24H18Cl2N2O4S4/c25-17-9-1-7-15-23(17)35(29,30)27-19-11-3-5-13-21(19)33-34-22-14-6-4-12-20(22)28-36(31,32)24-16-8-2-10-18(24)26/h1-16,27-28H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Teknologi MARA					Assay Description β-glucuronidase activity was determined by measuring absorbance at 405 nm of p-nitrophenol formed substrate by spectrophotometric method. 250 µL...				Bioorg Chem 68: 15-22 (2016) Article DOI: 10.1016/j.bioorg.2016.07.002 BindingDB Entry DOI: 10.7270/Q2542MCP
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50233855 (CHEMBL4095662) Show SMILES Cc1ncc(n1CCOC(=O)c1ccc2ncsc2c1)[N+]([O-])=O Show InChI InChI=1S/C14H12N4O4S/c1-9-15-7-13(18(20)21)17(9)4-5-22-14(19)10-2-3-11-12(6-10)23-8-16-11/h2-3,6-8H,4-5H2,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...				Eur J Med Chem 125: 1289-1299 (2017) Article DOI: 10.1016/j.ejmech.2016.11.031 BindingDB Entry DOI: 10.7270/Q2125VXZ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50277925 (CHEMBL4174351) Show SMILES Clc1ccc(c(Cl)c1)S(=O)(=O)Nc1cnc2ccccc2c1 Show InChI InChI=1S/C15H10Cl2N2O2S/c16-11-5-6-15(13(17)8-11)22(20,21)19-12-7-10-3-1-2-4-14(10)18-9-12/h1-9,19H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Antagonistic activity by inhibition histamine H2 receptor from rats.				Eur J Med Chem 139: 849-864 (2017) Article DOI: 10.1016/j.ejmech.2017.08.052 BindingDB Entry DOI: 10.7270/Q20P12HF
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM222115 ((E)-3-(2-(2-(Pyren-1-ylmethylene)hydrazinyl)thiazo...) Show SMILES Oc1cccc(c1)-c1csc(N\N=C\c2ccc3ccc4cccc5ccc2c3c45)n1 Show InChI InChI=1S/C26H17N3OS/c30-21-6-2-5-19(13-21)23-15-31-26(28-23)29-27-14-20-10-9-18-8-7-16-3-1-4-17-11-12-22(20)25(18)24(16)17/h1-15,30H,(H,28,29)/b27-14+	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi					Assay Description β-Glucuronidase inhibitory activity was measured by quantifying the absorbance of para-nitrophenol which was formed from the substrate by the sp...				Bioorg Chem 70: 199-209 (2017) Article DOI: 10.1016/j.bioorg.2016.12.011 BindingDB Entry DOI: 10.7270/Q2VH5MQ9
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50484066 (CHEMBL1808308) Show SMILES Oc1ccc(O)c(c1)-c1nc2ccccc2s1 Show InChI InChI=1S/C13H9NO2S/c15-8-5-6-11(16)9(7-8)13-14-10-3-1-2-4-12(10)17-13/h1-7,15-16H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta glucuronidase assessed as p-nitrophenol formation after 30 mins by spectrophotometric method				Bioorg Med Chem 19: 4286-94 (2011) Article DOI: 10.1016/j.bmc.2011.05.052 BindingDB Entry DOI: 10.7270/Q2FB55SC
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM50233859 (CHEMBL4074226) Show SMILES Cc1ncc(n1CCOC(=O)c1ccc(cc1)[N+]([O-])=O)[N+]([O-])=O Show InChI InChI=1S/C13H12N4O6/c1-9-14-8-12(17(21)22)15(9)6-7-23-13(18)10-2-4-11(5-3-10)16(19)20/h2-5,8H,6-7H2,1H3	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta glucuronidase using p-nitrophenyl-beta-D-glucuronide as substrate preincubated for 30 mins followed by substrate addi...				Eur J Med Chem 125: 1289-1299 (2017) Article DOI: 10.1016/j.ejmech.2016.11.031 BindingDB Entry DOI: 10.7270/Q2125VXZ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Bos taurus (Bovine))	BDBM33932 (4-(3H-1,3-benzothiazol-2-ylidene)-1-cyclohexa-2,5-...) Show SMILES Oc1ccc(cc1)-c1nc2ccccc2s1 Show InChI InChI=1S/C13H9NOS/c15-10-7-5-9(6-8-10)13-14-11-3-1-2-4-12(11)16-13/h1-8,15H	KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Karachi Curated by ChEMBL					Assay Description Inhibition of bovine liver beta glucuronidase assessed as p-nitrophenol formation after 30 mins by spectrophotometric method				Bioorg Med Chem 19: 4286-94 (2011) Article DOI: 10.1016/j.bmc.2011.05.052 BindingDB Entry DOI: 10.7270/Q2FB55SC
					More data for this Ligand-Target Pair

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