Compile Data Set for Download or QSAR

Found 216 hits of ic50 data for polymerid = 7020   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159725 (US9035059, 19-4) Show SMILES C\C=C/CCCCCOc1ccc(NS(=O)(=O)c2ccc3CN(Cc3c2)C(=O)Nc2ccc(cc2)C(C)(C)C)c(F)c1 Show InChI InChI=1S/C33H40FN3O4S/c1-5-6-7-8-9-10-19-41-28-16-18-31(30(34)21-28)36-42(39,40)29-17-11-24-22-37(23-25(24)20-29)32(38)35-27-14-12-26(13-15-27)33(2,3)4/h5-6,11-18,20-21,36H,7-10,19,22-23H2,1-4H3,(H,35,38)/b6-5-	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM50518069 (CHEMBL4542050 | US11479538, Example 22) Show SMILES Fc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ncc(s2)C2CC2)=C(C(=O)N1)n1nn[nH]c1=O)C(F)(F)F |r,c:28| Show InChI InChI=1S/C23H19F7N6O3S/c24-15-8-12(39-7-1-6-22(25,26)27)4-5-14(15)21(23(28,29)30)9-13(19-31-10-16(40-19)11-2-3-11)17(18(37)32-21)36-20(38)33-34-35-36/h4-5,8,10-11H,1-3,6-7,9H2,(H,32,37)(H,33,35,38)/t21-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SR2
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM50442175 (CHEMBL2441597) Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccno2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F |r,c:8| Show InChI InChI=1S/C27H23F6N3O4/c1-16-3-5-17(6-4-16)20-15-25(27(31,32)33,36-24(38)22(20)23(37)35-21-11-13-34-40-21)18-7-9-19(10-8-18)39-14-2-12-26(28,29)30/h3-11,13H,2,12,14-15H2,1H3,(H,35,37)(H,36,38)/t25-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human MGAT2 by LC/MS assay				ACS Med Chem Lett 4: 898-9 (2013) Article DOI: 10.1021/ml400272q BindingDB Entry DOI: 10.7270/Q2WD421M
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM289043 (US10093650, Example 20 | US10329273, Example 20 | ...) Show SMILES FC(F)(F)CCCCc1ccc(cc1)[C@@]1(CC(c2ccn(CC3CC3)n2)=C(C(=O)N1)n1nn[nH]c1=O)C(F)(F)F |r,c:28| Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SR2
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM50058840 (CHEMBL3325734) Show SMILES Cl.CS(=O)(=O)N[C@@H](c1ccc(CNC[C@H]2COc3cccnc3O2)cc1)C(F)(F)F |r| Show InChI InChI=1S/C18H20F3N3O4S.ClH/c1-29(25,26)24-16(18(19,20)21)13-6-4-12(5-7-13)9-22-10-14-11-27-15-3-2-8-23-17(15)28-14;/h2-8,14,16,22,24H,9-11H2,1H3;1H/t14-,16-;/m0./s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human MoGAT-2 expressed in human Caco2 cells assessed as inhibition of 2-O-Hexadecylglycerol hydrolysis pretreated for 30 mins by LC-MS...				ACS Med Chem Lett 5: 840-1 (2014) Article DOI: 10.1021/ml500217g BindingDB Entry DOI: 10.7270/Q2BZ67QZ
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159734 (US9035059, 23-1 | US9035059, 24-1/24-2) Show SMILES CC(N1CCc2cc(ccc2C1)S(=O)(=O)Nc1ccc(CCCC2CCCC2)cc1F)c1ccc(nc1)C(C)(C)C Show InChI InChI=1S/C34H44FN3O2S/c1-24(28-14-17-33(36-22-28)34(2,3)4)38-19-18-27-21-30(15-13-29(27)23-38)41(39,40)37-32-16-12-26(20-31(32)35)11-7-10-25-8-5-6-9-25/h12-17,20-22,24-25,37H,5-11,18-19,23H2,1-4H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	25
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159724 (US9035059, 19-3) Show SMILES CC(C)(C)c1ccc(NC(=O)N2Cc3ccc(cc3C2)S(=O)(=O)Nc2ccc(OCCCC3CCCC3)cc2F)cc1 Show InChI InChI=1S/C33H40FN3O4S/c1-33(2,3)26-11-13-27(14-12-26)35-32(38)37-21-24-10-16-29(19-25(24)22-37)42(39,40)36-31-17-15-28(20-30(31)34)41-18-6-9-23-7-4-5-8-23/h10-17,19-20,23,36H,4-9,18,21-22H2,1-3H3,(H,35,38)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159732 (US9035059, 20-4) Show SMILES CC(C)(C)c1ccc(cn1)C(C)(C)N1CCc2cc(ccc2C1)S(=O)(=O)Nc1ccc(CCCC2CCCC2)cc1F Show InChI InChI=1S/C35H46FN3O2S/c1-34(2,3)33-18-15-29(23-37-33)35(4,5)39-20-19-27-22-30(16-14-28(27)24-39)42(40,41)38-32-17-13-26(21-31(32)36)12-8-11-25-9-6-7-10-25/h13-18,21-23,25,38H,6-12,19-20,24H2,1-5H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	25
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM38176 (US10093650, Example 2 | US10329273, Example 2 | US...) Show SMILES Cc1ccc(cc1)C1=C(C(=O)N[C@@](C1)(c1ccc(OCCCCCC(F)(F)F)cc1)C(F)(F)F)n1nn[nH]c1=O |r,t:8| Show InChI InChI=1S/C15H10F2N2O3/c16-11-4-3-5-12(17)10(11)9-22-19-14-7-2-1-6-13(14)18(21)8-15(19)20/h1-8H,9H2	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SR2
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM400246 (US10329273, Example 17 | US11479538, Example 17) Show SMILES FC(F)(F)CCCCCCn1cc(cn1)[C@@]1(CC(=C(C(=O)N1)n1nn[nH]c1=O)c1ccc2CCCCc2c1)C(F)(F)F |r,c:18| Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SR2
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM400245 (US10329273, Example 16 | US11479538, Example 16) Show SMILES Fc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ccn(CC3CCC3)n2)=C(C(=O)N1)n1nn[nH]c1=O)C(F)(F)F |r,c:30| Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SR2
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM289003 (US10093650, Example 14 | US10093650, Example 16 | ...) Show SMILES Fc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ccn(CC3CC3)n2)=C(C(=O)N1)n1nn[nH]c1=O)C(F)(F)F |r,c:29| Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SR2
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159705 (US9035059, 18-7) Show SMILES CCCCCCCCOc1ccc(NS(=O)(=O)c2ccc3CN(Cc3c2)C(=O)Nc2ccc(cc2)C(C)(C)C)c(F)c1 Show InChI InChI=1S/C33H42FN3O4S/c1-5-6-7-8-9-10-19-41-28-16-18-31(30(34)21-28)36-42(39,40)29-17-11-24-22-37(23-25(24)20-29)32(38)35-27-14-12-26(13-15-27)33(2,3)4/h11-18,20-21,36H,5-10,19,22-23H2,1-4H3,(H,35,38)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM50442178 (CHEMBL2441600 | US9187424, 124) Show SMILES COc1ccc(NC(=O)C2=C(CC(NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)cc1 |t:9| Show InChI InChI=1S/C31H28F6N2O4/c1-19-4-6-20(7-5-19)25-18-29(31(35,36)37,21-8-12-24(13-9-21)43-17-3-16-30(32,33)34)39-28(41)26(25)27(40)38-22-10-14-23(42-2)15-11-22/h4-15H,3,16-18H2,1-2H3,(H,38,40)(H,39,41)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human MGAT2 by LC/MS assay				ACS Med Chem Lett 4: 898-9 (2013) Article DOI: 10.1021/ml400272q BindingDB Entry DOI: 10.7270/Q2WD421M
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM50442176 (CHEMBL2441598) Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccc(cc2)-c2nnn[nH]2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F |r,c:8| Show InChI InChI=1S/C31H26F6N6O3/c1-18-3-5-19(6-4-18)24-17-29(31(35,36)37,21-9-13-23(14-10-21)46-16-2-15-30(32,33)34)39-28(45)25(24)27(44)38-22-11-7-20(8-12-22)26-40-42-43-41-26/h3-14H,2,15-17H2,1H3,(H,38,44)(H,39,45)(H,40,41,42,43)/t29-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human MGAT2 by LC/MS assay				ACS Med Chem Lett 4: 898-9 (2013) Article DOI: 10.1021/ml400272q BindingDB Entry DOI: 10.7270/Q2WD421M
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM289026 (US10093650, Example 18 | US10329273, Example 18 | ...) Show SMILES CC(=O)c1ccc(s1)C1=C(C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)n1nn[nH]c1=O |r,t:9| Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SR2
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM50442175 (CHEMBL2441597) Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccno2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F |r,c:8| Show InChI InChI=1S/C27H23F6N3O4/c1-16-3-5-17(6-4-16)20-15-25(27(31,32)33,36-24(38)22(20)23(37)35-21-11-13-34-40-21)18-7-9-19(10-8-18)39-14-2-12-26(28,29)30/h3-11,13H,2,12,14-15H2,1H3,(H,35,37)(H,36,38)/t25-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human MGAT2 by SPA assay				ACS Med Chem Lett 4: 898-9 (2013) Article DOI: 10.1021/ml400272q BindingDB Entry DOI: 10.7270/Q2WD421M
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM211296 (US10093650, Example 11 | US10329273, Example 11 | ...) Show SMILES Fc1cc(CCCCC(F)(F)F)ccc1[C@@]1(CC(c2ccn(CC3CC3)n2)=C(C(=O)N1)n1nn[nH]c1=O)C(F)(F)F |r,c:29| Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SR2
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM50442176 (CHEMBL2441598) Show SMILES Cc1ccc(cc1)C1=C(C(=O)Nc2ccc(cc2)-c2nnn[nH]2)C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F |r,c:8| Show InChI InChI=1S/C31H26F6N6O3/c1-18-3-5-19(6-4-18)24-17-29(31(35,36)37,21-9-13-23(14-10-21)46-16-2-15-30(32,33)34)39-28(45)25(24)27(44)38-22-11-7-20(8-12-22)26-40-42-43-41-26/h3-14H,2,15-17H2,1H3,(H,38,44)(H,39,45)(H,40,41,42,43)/t29-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human MGAT2 by SPA assay				ACS Med Chem Lett 4: 898-9 (2013) Article DOI: 10.1021/ml400272q BindingDB Entry DOI: 10.7270/Q2WD421M
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159711 (US9035059, 18-16) Show SMILES CC(C)(C)c1ccc(NC(=O)N2Cc3ccc(cc3C2)S(=O)(=O)Nc2ccc(OCCCCCc3ccccc3)cc2F)cc1 Show InChI InChI=1S/C36H40FN3O4S/c1-36(2,3)29-14-16-30(17-15-29)38-35(41)40-24-27-13-19-32(22-28(27)25-40)45(42,43)39-34-20-18-31(23-33(34)37)44-21-9-5-8-12-26-10-6-4-7-11-26/h4,6-7,10-11,13-20,22-23,39H,5,8-9,12,21,24-25H2,1-3H3,(H,38,41)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM289044 (US10093650, Example 21 | US10329273, Example 21 | ...) Show SMILES FC(F)c1ccc(cc1)C1=C(C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1F)C(F)(F)F)n1nn[nH]c1=O |r,t:10| Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SR2
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM289042 (US10093650, Example 19 | US10329273, Example 19 | ...) Show SMILES CC(O)c1ccc(s1)C1=C(C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)n1nn[nH]c1=O |r,t:9| Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SR2
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159740 (US9035059, 24-11 | US9035059, 24-5/24-6) Show SMILES CC(C)N1CCc2cc(ccc2C1)S(=O)(=O)Nc1ccc(CCCC2CCCC2)cc1F Show InChI InChI=1S/C26H35FN2O2S/c1-19(2)29-15-14-22-17-24(12-11-23(22)18-29)32(30,31)28-26-13-10-21(16-25(26)27)9-5-8-20-6-3-4-7-20/h10-13,16-17,19-20,28H,3-9,14-15,18H2,1-2H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	25
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159736 (US9035059, 23-3) Show SMILES CC(N1CCc2cc(ccc2C1)S(=O)(=O)Nc1ccc(CCCC2CCCC2)cc1F)c1ccnc(c1)C(C)(C)C Show InChI InChI=1S/C34H44FN3O2S/c1-24(27-16-18-36-33(22-27)34(2,3)4)38-19-17-28-21-30(14-13-29(28)23-38)41(39,40)37-32-15-12-26(20-31(32)35)11-7-10-25-8-5-6-9-25/h12-16,18,20-22,24-25,37H,5-11,17,19,23H2,1-4H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	25
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159734 (US9035059, 23-1 | US9035059, 24-1/24-2) Show SMILES CC(N1CCc2cc(ccc2C1)S(=O)(=O)Nc1ccc(CCCC2CCCC2)cc1F)c1ccc(nc1)C(C)(C)C Show InChI InChI=1S/C34H44FN3O2S/c1-24(28-14-17-33(36-22-28)34(2,3)4)38-19-18-27-21-30(15-13-29(27)23-38)41(39,40)37-32-16-12-26(20-31(32)35)11-7-10-25-8-5-6-9-25/h12-17,20-22,24-25,37H,5-11,18-19,23H2,1-4H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159730 (US9035059, 20-2) Show SMILES CC(C)(C)c1ccc(CC(C)(C)N2CCc3cc(ccc3C2)S(=O)(=O)Nc2ccc(CCCC3CCCC3)cc2F)cc1 Show InChI InChI=1S/C37H49FN2O2S/c1-36(2,3)32-17-13-29(14-18-32)25-37(4,5)40-22-21-30-24-33(19-16-31(30)26-40)43(41,42)39-35-20-15-28(23-34(35)38)12-8-11-27-9-6-7-10-27/h13-20,23-24,27,39H,6-12,21-22,25-26H2,1-5H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	25
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159735 (US9035059, 23-2) Show SMILES CC(N1CCc2cc(ccc2C1)S(=O)(=O)Nc1ccc(OCCCCCc2ccccc2)cc1F)c1ccc(nc1)C(C)(C)C Show InChI InChI=1S/C37H44FN3O3S/c1-27(30-15-19-36(39-25-30)37(2,3)4)41-21-20-29-23-33(17-14-31(29)26-41)45(42,43)40-35-18-16-32(24-34(35)38)44-22-10-6-9-13-28-11-7-5-8-12-28/h5,7-8,11-12,14-19,23-25,27,40H,6,9-10,13,20-22,26H2,1-4H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM50442178 (CHEMBL2441600 | US9187424, 124) Show SMILES COc1ccc(NC(=O)C2=C(CC(NC2=O)(c2ccc(OCCCC(F)(F)F)cc2)C(F)(F)F)c2ccc(C)cc2)cc1 |t:9| Show InChI InChI=1S/C31H28F6N2O4/c1-19-4-6-20(7-5-19)25-18-29(31(35,36)37,21-8-12-24(13-9-21)43-17-3-16-30(32,33)34)39-28(41)26(25)27(40)38-22-10-14-23(42-2)15-11-22/h4-15H,3,16-18H2,1-2H3,(H,38,40)(H,39,41)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Inhibition of human MGAT2 by SPA assay				ACS Med Chem Lett 4: 898-9 (2013) Article DOI: 10.1021/ml400272q BindingDB Entry DOI: 10.7270/Q2WD421M
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159657 (US9035059, 7-76) Show SMILES Cc1ccc(cc1)-n1cc(CN2CCc3cc(ccc3C2)S(=O)(=O)Nc2ccc(CCCC3CCCC3)cc2F)cn1 Show InChI InChI=1S/C34H39FN4O2S/c1-25-9-13-31(14-10-25)39-23-28(21-36-39)22-38-18-17-29-20-32(15-12-30(29)24-38)42(40,41)37-34-16-11-27(19-33(34)35)8-4-7-26-5-2-3-6-26/h9-16,19-21,23,26,37H,2-8,17-18,22,24H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	25
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM152809 (US8993568, 5) Show SMILES CS(=O)(=O)N[C@@H](c1ccc(CN2CCOC(C2)c2ccccc2Cl)cc1)C(F)(F)F |r| Show InChI InChI=1S/C20H22ClF3N2O3S/c1-30(27,28)25-19(20(22,23)24)15-8-6-14(7-9-15)12-26-10-11-29-18(13-26)16-4-2-3-5-17(16)21/h2-9,18-19,25H,10-13H2,1H3/t18?,19-/m0/s1	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	4
Eli Lilly and Company US Patent					Assay Description The in vitro inhibitory activity of compounds against human MOGAT-2 is evaluated in this assay. MOGAT-2 transfers an oleoyl group to monooleoyl-glyce...				US Patent US8993568 (2015) BindingDB Entry DOI: 10.7270/Q2WM1C4M
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM38181 (US10093650, Example 4 | US10329273, Example 4 | US...) Show SMILES FC(F)Oc1ccc(cc1)C1=C(C(=O)N[C@@](C1)(c1ccc(OCCCCCC(F)(F)F)cc1)C(F)(F)F)n1nn[nH]c1=O |r,t:11| Show InChI InChI=1S/C17H21ClN2O2/c18-13-6-8-15(9-7-13)20-11-12(10-16(20)21)17(22)19-14-4-2-1-3-5-14/h6-9,12,14H,1-5,10-11H2,(H,19,22)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SR2
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159729 (US9035059, 19-12) Show SMILES CC(C)(C)c1ccc(NC(=O)N2Cc3ccc(cc3C2)S(=O)(=O)Nc2ccc(OCCc3ccccn3)cc2F)cc1 Show InChI InChI=1S/C32H33FN4O4S/c1-32(2,3)24-8-10-26(11-9-24)35-31(38)37-20-22-7-13-28(18-23(22)21-37)42(39,40)36-30-14-12-27(19-29(30)33)41-17-15-25-6-4-5-16-34-25/h4-14,16,18-19,36H,15,17,20-21H2,1-3H3,(H,35,38)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159701 (US9035059, 17-5) Show SMILES CC(C)(C)c1ccc(CCN2CCc3cc(ccc3C2)S(=O)(=O)Nc2ccc(OCCCCCc3ccccc3)cc2F)cc1 Show InChI InChI=1S/C38H45FN2O3S/c1-38(2,3)33-16-13-30(14-17-33)21-23-41-24-22-31-26-35(19-15-32(31)28-41)45(42,43)40-37-20-18-34(27-36(37)39)44-25-9-5-8-12-29-10-6-4-7-11-29/h4,6-7,10-11,13-20,26-27,40H,5,8-9,12,21-25,28H2,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159636 (US9035059, 6-75) Show SMILES CC(C)(C)c1ccc(CCN2CCc3cc(ccc3C2)S(=O)(=O)Nc2ccc(CCCC3CCOCC3)cc2F)cc1 Show InChI InChI=1S/C35H45FN2O3S/c1-35(2,3)31-11-7-27(8-12-31)15-19-38-20-16-29-24-32(13-10-30(29)25-38)42(39,40)37-34-14-9-28(23-33(34)36)6-4-5-26-17-21-41-22-18-26/h7-14,23-24,26,37H,4-6,15-22,25H2,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159682 (US9035059, 10-5/10-6) Show SMILES CC(Cc1ccc(cc1)C(C)(C)C)N1CCc2cc(ccc2C1)S(=O)(=O)Nc1ccc(CCCC2CCCC2)cc1F Show InChI InChI=1S/C36H47FN2O2S/c1-26(22-29-12-16-32(17-13-29)36(2,3)4)39-21-20-30-24-33(18-15-31(30)25-39)42(40,41)38-35-19-14-28(23-34(35)37)11-7-10-27-8-5-6-9-27/h12-19,23-24,26-27,38H,5-11,20-22,25H2,1-4H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159624 (US9035059, 6-33) Show SMILES CCCCCCCCOc1ccc(NS(=O)(=O)c2ccc3CN(Cc4ccc(nc4)C(C)(C)C)CCc3c2)c(F)c1 Show InChI InChI=1S/C33H44FN3O3S/c1-5-6-7-8-9-10-19-40-28-13-15-31(30(34)21-28)36-41(38,39)29-14-12-27-24-37(18-17-26(27)20-29)23-25-11-16-32(35-22-25)33(2,3)4/h11-16,20-22,36H,5-10,17-19,23-24H2,1-4H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159708 (US9035059, 18-12) Show SMILES CC(C)(C)c1ccc(NC(=O)N2Cc3ccc(cc3C2)S(=O)(=O)Nc2ccc(OCCCC3CCCCC3)cc2F)cc1 Show InChI InChI=1S/C34H42FN3O4S/c1-34(2,3)27-12-14-28(15-13-27)36-33(39)38-22-25-11-17-30(20-26(25)23-38)43(40,41)37-32-18-16-29(21-31(32)35)42-19-7-10-24-8-5-4-6-9-24/h11-18,20-21,24,37H,4-10,19,22-23H2,1-3H3,(H,36,39)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159681 (US9035059, 10-3/10-4) Show SMILES CCCCCCOc1ccc(NS(=O)(=O)c2ccc3CN(CCc3c2)C(C)Cc2ccc(cc2)C(C)(C)C)c(F)c1 Show InChI InChI=1S/C34H45FN2O3S/c1-6-7-8-9-20-40-30-15-17-33(32(35)23-30)36-41(38,39)31-16-12-28-24-37(19-18-27(28)22-31)25(2)21-26-10-13-29(14-11-26)34(3,4)5/h10-17,22-23,25,36H,6-9,18-21,24H2,1-5H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM578481 ((S)-3-(5-Oxo-4,5-dihydro-1H-tetrazol-1-yl)-4-(p-to...) Show SMILES Cc1ccc(cc1)C1=C(C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)n1nn[nH]c1=O |r,t:8| Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SR2
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159727 (US9035059, 19-8) Show SMILES CCCCCCCOc1ccc(NS(=O)(=O)c2ccc3CN(Cc3c2)C(=O)Nc2ccc(cc2)C(C)(C)C)c(F)c1 Show InChI InChI=1S/C32H40FN3O4S/c1-5-6-7-8-9-18-40-27-15-17-30(29(33)20-27)35-41(38,39)28-16-10-23-21-36(22-24(23)19-28)31(37)34-26-13-11-25(12-14-26)32(2,3)4/h10-17,19-20,35H,5-9,18,21-22H2,1-4H3,(H,34,37)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159615 (US9035059, 6-17) Show SMILES CC(C)(C)c1ccc(CCN2CCc3cc(ccc3C2)S(=O)(=O)Nc2ccc(CCCC3CCCC3)cc2F)cc1 Show InChI InChI=1S/C35H45FN2O2S/c1-35(2,3)31-15-11-27(12-16-31)19-21-38-22-20-29-24-32(17-14-30(29)25-38)41(39,40)37-34-18-13-28(23-33(34)36)10-6-9-26-7-4-5-8-26/h11-18,23-24,26,37H,4-10,19-22,25H2,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159707 (US9035059, 18-11) Show SMILES CC(C)(C)c1ccc(NC(=O)N2Cc3ccc(cc3C2)S(=O)(=O)Nc2ccc(OCCC3CCCCC3)cc2F)cc1 Show InChI InChI=1S/C33H40FN3O4S/c1-33(2,3)26-10-12-27(13-11-26)35-32(38)37-21-24-9-15-29(19-25(24)22-37)42(39,40)36-31-16-14-28(20-30(31)34)41-18-17-23-7-5-4-6-8-23/h9-16,19-20,23,36H,4-8,17-18,21-22H2,1-3H3,(H,35,38)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159734 (US9035059, 23-1 | US9035059, 24-1/24-2) Show SMILES CC(N1CCc2cc(ccc2C1)S(=O)(=O)Nc1ccc(CCCC2CCCC2)cc1F)c1ccc(nc1)C(C)(C)C Show InChI InChI=1S/C34H44FN3O2S/c1-24(28-14-17-33(36-22-28)34(2,3)4)38-19-18-27-21-30(15-13-29(27)23-38)41(39,40)37-32-16-12-26(20-31(32)35)11-7-10-25-8-5-6-9-25/h12-17,20-22,24-25,37H,5-11,18-19,23H2,1-4H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	25
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159666 (US9035059, 8-5) Show SMILES CC(C)(C)c1ccc(CCN2CCc3cc(ccc3C2)S(=O)(=O)Nc2ccc(OCCC3CCCC3)cc2F)cc1 Show InChI InChI=1S/C34H43FN2O3S/c1-34(2,3)29-11-8-26(9-12-29)16-19-37-20-17-27-22-31(14-10-28(27)24-37)41(38,39)36-33-15-13-30(23-32(33)35)40-21-18-25-6-4-5-7-25/h8-15,22-23,25,36H,4-7,16-21,24H2,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	25
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM38204 (US10093650, Example 8 | US10329273, Example 8 | US...) Show SMILES Fc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ccn(n2)C2CCC2)=C(C(=O)N1)n1nn[nH]c1=O)C(F)(F)F |r,c:29| Show InChI InChI=1S/C19H26N2O4S/c1-2-25-18-8-9-19(17-7-4-3-6-16(17)18)26(22,23)20-10-5-11-21-12-14-24-15-13-21/h3-4,6-9,20H,2,5,10-15H2,1H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The MGAT enzyme reactions were performed in Corning FALCON® 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SR2
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159723 (US9035059, 19-2) Show SMILES CC(C)(C)c1ccc(NC(=O)N2Cc3ccc(cc3C2)S(=O)(=O)Nc2ccc(OCCCCc3ccccc3)cc2F)cc1 Show InChI InChI=1S/C35H38FN3O4S/c1-35(2,3)28-13-15-29(16-14-28)37-34(40)39-23-26-12-18-31(21-27(26)24-39)44(41,42)38-33-19-17-30(22-32(33)36)43-20-8-7-11-25-9-5-4-6-10-25/h4-6,9-10,12-19,21-22,38H,7-8,11,20,23-24H2,1-3H3,(H,37,40)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159622 (US9035059, 6-31) Show SMILES CC(C)(C)c1ccc(CN2CCc3cc(ccc3C2)S(=O)(=O)Nc2ccc(CCCC3CCCC3)cc2F)cn1 Show InChI InChI=1S/C33H42FN3O2S/c1-33(2,3)32-16-12-26(21-35-32)22-37-18-17-27-20-29(14-13-28(27)23-37)40(38,39)36-31-15-11-25(19-30(31)34)10-6-9-24-7-4-5-8-24/h11-16,19-21,24,36H,4-10,17-18,22-23H2,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159683 (US9035059, 10-7/10-8) Show SMILES CCCCCCCc1ccc(NS(=O)(=O)c2ccc3CN(CCc3c2)C(C)Cc2ccc(cc2)C(C)(C)C)c(F)c1 Show InChI InChI=1S/C35H47FN2O2S/c1-6-7-8-9-10-11-27-14-19-34(33(36)23-27)37-41(39,40)32-18-15-30-25-38(21-20-29(30)24-32)26(2)22-28-12-16-31(17-13-28)35(3,4)5/h12-19,23-24,26,37H,6-11,20-22,25H2,1-5H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159623 (US9035059, 6-32) Show SMILES CCCCCCCc1ccc(NS(=O)(=O)c2ccc3CN(Cc4ccc(nc4)C(C)(C)C)CCc3c2)c(F)c1 Show InChI InChI=1S/C32H42FN3O2S/c1-5-6-7-8-9-10-24-11-15-30(29(33)19-24)35-39(37,38)28-14-13-27-23-36(18-17-26(27)20-28)22-25-12-16-31(34-21-25)32(2,3)4/h11-16,19-21,35H,5-10,17-18,22-23H2,1-4H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair
2-acylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM159718 (US9035059, 18-25) Show SMILES CC(C)(C)c1ccc(NC(=O)N2Cc3ccc(cc3C2)S(=O)(=O)Nc2ccc(OCCCCOc3ccccc3)cc2F)cc1 Show InChI InChI=1S/C35H38FN3O5S/c1-35(2,3)27-12-14-28(15-13-27)37-34(40)39-23-25-11-17-31(21-26(25)24-39)45(41,42)38-33-18-16-30(22-32(33)36)44-20-8-7-19-43-29-9-5-4-6-10-29/h4-6,9-18,21-22,38H,7-8,19-20,23-24H2,1-3H3,(H,37,40)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TAISHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....				US Patent US9035059 (2015) BindingDB Entry DOI: 10.7270/Q2B856WH
					More data for this Ligand-Target Pair

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