Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5,6-dihydroxyindole-2-carboxylic acid oxidase (Mus musculus (Mouse)) | BDBM152929 (US8993596, Compound 24) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 150 | n/a | n/a | n/a | n/a | 6.8 | 37 |
Galderma Research & Development US Patent | Assay Description The activity of the inhibitors is measured using a lysate of B16F1 cells (murine melanoma line). In the presence of the L-tyrosine substrate, the tyr... | US Patent US8993596 (2015) BindingDB Entry DOI: 10.7270/Q2HD7TDC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5,6-dihydroxyindole-2-carboxylic acid oxidase (Mus musculus (Mouse)) | BDBM152928 (US8993596, Compound 48) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 200 | n/a | n/a | n/a | n/a | 6.8 | 37 |
Galderma Research & Development US Patent | Assay Description The activity of the inhibitors is measured using a lysate of B16F1 cells (murine melanoma line). In the presence of the L-tyrosine substrate, the tyr... | US Patent US8993596 (2015) BindingDB Entry DOI: 10.7270/Q2HD7TDC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5,6-dihydroxyindole-2-carboxylic acid oxidase (Mus musculus (Mouse)) | BDBM50248158 (CHEMBL450195 | N-butylresorcinol | US8993596, 4-Bu...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | 6.8 | 37 |
Galderma Research & Development US Patent | Assay Description The activity of the inhibitors is measured using a lysate of B16F1 cells (murine melanoma line). In the presence of the L-tyrosine substrate, the tyr... | US Patent US8993596 (2015) BindingDB Entry DOI: 10.7270/Q2HD7TDC | |||||||||||
More data for this Ligand-Target Pair |