Compile Data Set for Download or QSAR

Found 227 hits of kd data for polymerid = 7285   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM443127 (US10654833, Compound 1) Show SMILES CC(C)n1cnnc1-c1cccc(n1)N1Cc2ccc(cc2C1=O)-c1cccc(c1)C(O)=O Show InChI InChI=1S/C25H21N5O3/c1-15(2)30-14-26-28-23(30)21-7-4-8-22(27-21)29-13-19-10-9-17(12-20(19)24(29)31)16-5-3-6-18(11-16)25(32)33/h3-12,14-15H,13H2,1-2H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a
Hepatikos Therapeutics, LLC US Patent					Assay Description Compound binding to the ASK1 kinase active site was determined using the KINOMEscan Assay platform (DiscoverX, San Diego, Calif.). Briefly, ASK1-tagg...				US Patent US10654833 (2020) BindingDB Entry DOI: 10.7270/Q2F192R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM443140 (US10654833, Compound 39 | US10654833, Compound 67) Show SMILES CC(C)n1cnnc1-c1cccc(n1)N1Cc2ccc(cc2C1=O)-c1ccc(C(O)=O)c(F)c1 Show InChI InChI=1S/C25H20FN5O3/c1-14(2)31-13-27-29-23(31)21-4-3-5-22(28-21)30-12-17-7-6-15(10-19(17)24(30)32)16-8-9-18(25(33)34)20(26)11-16/h3-11,13-14H,12H2,1-2H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	0.860	n/a	n/a	n/a	n/a	n/a
Hepatikos Therapeutics, LLC US Patent					Assay Description Compound binding to the ASK1 kinase active site was determined using the KINOMEscan Assay platform (DiscoverX, San Diego, Calif.). Briefly, ASK1-tagg...				US Patent US10654833 (2020) BindingDB Entry DOI: 10.7270/Q2F192R3
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50560389 (CHEMBL4744428) Show SMILES CC(C)n1cnnc1-c1cccc(NC(=O)[C@H]2CN(CCO2)c2ccc(nc2)C2CC2)n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to ASK1 (unknown origin)				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127405 BindingDB Entry DOI: 10.7270/Q2JQ14Q8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50308060 (16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...) Show SMILES C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4C(=O)NCc4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C26H21N3O4/c1-25-26(32,12-30)10-18(33-25)28-16-8-4-2-6-13(16)20-21-15(11-27-24(21)31)19-14-7-3-5-9-17(14)29(25)23(19)22(20)28/h2-9,18,30,32H,10-12H2,1H3,(H,27,31)/t18-,25+,26+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding affinity to ASK1				Blood 114: 2984-92 (2009) Article DOI: 10.1182/blood-2009-05-222034 BindingDB Entry DOI: 10.7270/Q2PN95V2
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50308060 (16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...) Show SMILES C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4C(=O)NCc4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C26H21N3O4/c1-25-26(32,12-30)10-18(33-25)28-16-8-4-2-6-13(16)20-21-15(11-27-24(21)31)19-14-7-3-5-9-17(14)29(25)23(19)22(20)28/h2-9,18,30,32H,10-12H2,1H3,(H,27,31)/t18-,25+,26+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a
Ambit Biosciences Curated by ChEMBL					Assay Description Binding constant for ASK1 kinase domain				Nat Biotechnol 29: 1046-51 (2011) Article DOI: 10.1038/nbt.1990 BindingDB Entry DOI: 10.7270/Q25D8S70
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503670 (US11034671, Example 61) Show SMILES Cc1cc2OCCCCn3cnnc3-c3cccc(NC(=O)c2cc1-n1cnc(c1)C1CC1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503671 (US11034671, Example 63) Show SMILES O=C1Nc2cccc(n2)-c2nncn2CCCCOc2ccc(cc12)-c1ccc(nc1)C#N Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503673 (US11034671, Example 65) Show SMILES Cc1cc2OCCCCn3cnnc3-c3cccc(NC(=O)c2cc1-c1ccc(nc1)C1CC1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503674 (US11034671, Example 66) Show SMILES O=C1Nc2cccc(n2)-c2nncn2CCCOc2ccc(cc12)-n1cnc(c1)C1CC1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503675 (US11034671, Example 67) Show SMILES CC1CCOc2ccc(cc2C(=O)Nc2cccc(n2)-c2nncn12)-c1ccc(C)nc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503676 (US11034671, Example 68 | US11168095, Example 59) Show SMILES Fc1cc2OCCCCn3cnnc3-c3cccc(NC(=O)c2cc1-c1ccc(nc1)C1CC1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503677 (US11034671, Example 69) Show SMILES Cc1ccc(cn1)-c1ccc2OCC3C[C@@H](C3)n3cnnc3-c3cccc(NC(=O)c2c1)n3 |r,wU:15.15,(-9.19,3.24,;-7.85,2.47,;-7.85,.93,;-6.52,.16,;-5.19,.93,;-5.19,2.47,;-6.52,3.24,;-3.85,.16,;-3.85,-1.38,;-2.52,-2.15,;-1.18,-1.38,;.15,-2.15,;1.48,-1.38,;2.82,-2.15,;3.91,-3.24,;4.99,-2.15,;3.91,-1.06,;6.82,-1.38,;8.28,-1.86,;9.19,-.61,;8.28,.64,;6.82,.16,;5.48,.93,;5.48,2.47,;4.15,3.24,;2.82,2.47,;2.82,.93,;1.48,.16,;.15,.93,;.15,2.47,;-1.18,.16,;-2.52,.93,;4.15,.16,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503678 (US11034671, Example 70) Show SMILES Cc1ccc(cn1)-c1ccc2COCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503679 (US11034671, Example 71) Show SMILES Cc1ccc(cn1)-c1ccc2OC3CC[C@@H](CC3)n3cnnc3-c3cccc(NC(=O)c2c1)n3 |r,wU:15.19,(-8.52,1.54,;-7.19,.77,;-7.19,-.77,;-5.85,-1.54,;-4.52,-.77,;-4.52,.77,;-5.85,1.54,;-3.19,-1.54,;-3.19,-3.08,;-1.85,-3.85,;-.52,-3.08,;.82,-3.85,;2.15,-3.08,;3.48,-3.85,;4.82,-3.08,;4.82,-1.54,;3.48,-.77,;2.15,-1.54,;6.15,-.77,;7.61,-1.25,;8.52,,;7.61,1.25,;6.15,.77,;4.82,1.54,;4.82,3.08,;3.48,3.85,;2.15,3.08,;2.15,1.54,;.82,.77,;.82,-.77,;2.36,-.77,;-.52,-1.54,;-1.85,-.77,;3.48,.77,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503681 (US11034671, Example 73) Show SMILES Cc1ncc(cn1)-c1ccc2OCCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503682 (US11034671, Example 74) Show SMILES Cc1ncc(cc1F)-c1ccc2OCCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503684 (US11034671, Example 77) Show SMILES Cc1ccc(cn1)-c1ccc2OCC3C[C@@H]3Cn3cnnc3-c3cccc(NC(=O)c2c1)n3 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503685 (US11034671, Example 78) Show SMILES CC(F)(F)c1ccc(cn1)-c1ccc2OCCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503687 (US11034671, Example 80) Show SMILES CC1CCOc2ccc(cc2C(=O)Nc2cccc(n2)-c2nncn2C1)-c1ccc(C)nc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503688 (US11034671, Example 81) Show SMILES Cc1ccc(cn1)-c1ccc2OCC3C[C@H]3Cn3cnnc3-c3cccc(NC(=O)c2c1)n3 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503689 (US11034671, Example 82) Show SMILES FC(F)c1ccc(cn1)-c1ccc2COCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503691 (US11034671, Example 84) Show SMILES FC(F)c1ccc(cn1)-c1ccc2OC3CC[C@@H](CC3)n3cnnc3-c3cccc(NC(=O)c2c1)n3 |r,wU:17.21,(-9.19,.77,;-7.85,1.54,;-7.85,3.08,;-6.52,.77,;-6.52,-.77,;-5.19,-1.54,;-3.85,-.77,;-3.85,.77,;-5.19,1.54,;-2.52,-1.54,;-2.52,-3.08,;-1.18,-3.85,;.15,-3.08,;1.48,-3.85,;2.82,-3.08,;4.15,-3.85,;5.48,-3.08,;5.48,-1.54,;4.15,-.77,;2.82,-1.54,;6.82,-.77,;8.28,-1.25,;9.19,,;8.28,1.25,;6.82,.77,;5.48,1.54,;5.48,3.08,;4.15,3.85,;2.82,3.08,;2.82,1.54,;1.48,.77,;1.48,-.77,;3.02,-.77,;.15,-1.54,;-1.18,-.77,;4.15,.77,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503692 (US11034671, Example 86) Show SMILES FC(F)c1ccc(cn1)-c1ccc2OC3CC[C@@H](C3)n3cnnc3-c3cccc(NC(=O)c2c1)n3 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503693 (US11034671, Example 87) Show SMILES FCc1ccc(cn1)-c1ccc2OCCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503694 (General Procedure for Compounds Example 88 & Examp...) Show SMILES C[C@H]1CCCOc2ccc(cc2C(=O)Nc2cccc(n2)-c2nncn12)-c1ccc(C)nc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503695 (US11034671, Example 89) Show SMILES C[C@@H]1CCCOc2ccc(cc2C(=O)Nc2cccc(n2)-c2nncn12)-c1ccc(C)nc1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503698 (US11034671, Example 92) Show SMILES CCc1ccc(cn1)-c1ccc2SCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503701 (US11034671, Example 95) Show SMILES O=C1Nc2cccc(n2)-c2nncn2CCCOCc2ccc(cc12)-c1ccc(nc1)C1CC1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503703 (US11034671, Example 97) Show SMILES Cc1ccc(cn1)-c1ccc2OCCC3C[C@H]3n3cnnc3-c3cccc(NC(=O)c2c1)n3 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503704 (US11034671, Example 98) Show SMILES Fc1cc(cnc1F)-c1ccc2OCCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503705 (US11034671, Example 99) Show SMILES Fc1ncc(cc1Cl)-c1ccc2OCCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503706 (US11034671, Example 100) Show SMILES FCc1ccc(cn1)-c1ccc2COCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503708 (US11034671, Example 102) Show SMILES CCc1ccc(cn1)-c1ccc2COCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503709 (US11034671, Example 103) Show SMILES O=C1Nc2cccc(n2)-c2nncn2CCCOCc2ccc(cc12)-n1cnc(c1)C1CC1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503710 (US11034671, Example 104) Show SMILES C[C@@H]1CCn2cnnc2-c2cccc(NC(=O)c3cc(ccc3OC1)-c1ccc(C)nc1)n2 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503711 (US11034671, Example 105) Show SMILES FCCc1ccc(cn1)-c1ccc2OCCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503614 (US11034671, Example 1) Show SMILES COc1ccc2OC\C=C\CCn3cnnc3-c3cccc(NC(=O)c2c1)n3 |t:8| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503615 (US11034671, Example 2) Show SMILES COc1ccc2OCCCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503620 (US11034671, Example 7) Show SMILES COc1ccc2OCCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503623 (US11034671, Example 10) Show SMILES Brc1ccc2OCCC=CCn3cnnc3-c3cccc(NC(=O)c2c1)n3 |w:9.9| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503624 (US11034671, Example 11) Show SMILES COc1ccc2OCCCCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503631 (US11034671, Example 18) Show SMILES O=C1Nc2cccc(n2)-c2nncn2C\C=C\COc2ccc(OCc3ccccc3)cc12 |t:17| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503635 (US11034671, Example 22 | US11168095, Example 22) Show SMILES O=C1Nc2cccc(n2)-c2nncn2CCCCOc2ccc(cc12)-n1cnc(c1)C1CC1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503636 (US11034671, Example 23) Show SMILES O=C1Nc2cccc(n2)-c2nncn2CCCCOc2ccc(cc12)-c1ccc(nc1)C1CC1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503637 (US11034671, Example 24) Show SMILES Cc1ccc(cn1)-c1ccc2OCCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503642 (US11034671, Example 30) Show SMILES CC1(C)Cc2cc3OCCCCn4cnnc4-c4cccc(NC(=O)c3cc2O1)n4 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503643 (US11034671, Example 31 | US11168095, Example 20) Show SMILES O=C1Nc2cccc(n2)-c2nncn2CCCCOc2ccc(cc12)C#N Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503647 (US11034671, Example 37) Show SMILES O=C1Nc2cccc(n2)-c2nncn2CCCOc2ccc(cc12)-c1ccc(nc1)C1CC1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503648 (US11034671, Example 38) Show SMILES O=C1Nc2cccc(n2)-c2nncn2CCCCOc2ccc(cc12)-c1ccccc1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM503649 (US11034671, Example 39) Show SMILES Fc1ccc(cn1)-c1ccc2OCCCCn3cnnc3-c3cccc(NC(=O)c2c1)n3 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The binding of compounds to ASK1 were determined using DiscoverX's proprietary technology. KINOMEscan™ is based on a competition binding assay th...				Citation and Details BindingDB Entry DOI: 10.7270/Q2S185M8
					More data for this Ligand-Target Pair

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