BindingDB PrimarySearch

Found 17 hits of ic50 data for polymerid = 7476
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50422383 (CHEMBL1203235) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Antagonist affinity [non competitive (irreversible)] at alpha-1D-adrenoreceptors on isolated thoracic aorta from rat				J Med Chem 44: 362-71 (2001) BindingDB Entry DOI: 10.7270/Q289175Q
University of Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50422380 (CHEMBL1203232) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Antagonist affinity [non competitive (irreversible)] at alpha-1D-adrenoreceptors on isolated thoracic aorta from rat				J Med Chem 44: 362-71 (2001) BindingDB Entry DOI: 10.7270/Q289175Q
University of Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50422382 (CHEMBL1203233) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.90	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Antagonist affinity [non competitive (irreversible)] at alpha-1D-adrenoreceptors on isolated thoracic aorta from rat				J Med Chem 44: 362-71 (2001) BindingDB Entry DOI: 10.7270/Q289175Q
University of Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50057463 (1-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piper...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description Binding affinity was tested on cloned rat Alpha-1D adrenergic receptor				J Med Chem 40: 1293-315 (1997) Article DOI: 10.1021/jm960697s BindingDB Entry DOI: 10.7270/Q2W096MN
Pfizer Central Research Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50422381 (CHEMBL384790) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Antagonist affinity [non competitive (irreversible)] at alpha-1D-adrenoreceptors on isolated thoracic aorta from rat				J Med Chem 44: 362-71 (2001) BindingDB Entry DOI: 10.7270/Q289175Q
University of Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50422379 (CHEMBL263289) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Antagonist affinity [non competitive (irreversible)] at alpha-1D-adrenoreceptors on isolated thoracic aorta from rat				J Med Chem 44: 362-71 (2001) BindingDB Entry DOI: 10.7270/Q289175Q
University of Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50422384 (CHEMBL216443) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Antagonist affinity [non competitive (irreversible)] at alpha-1D-adrenoreceptors on isolated thoracic aorta from rat				J Med Chem 44: 362-71 (2001) BindingDB Entry DOI: 10.7270/Q289175Q
University of Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50057486 (2-[1-(3,4-Dimethoxy-benzyl)-6,7-dimethoxy-3,4-dihy...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Central Research Curated by ChEMBL					Assay Description Binding affinity was tested on cloned rat Alpha-1D adrenergic receptor				J Med Chem 40: 1293-315 (1997) Article DOI: 10.1021/jm960697s BindingDB Entry DOI: 10.7270/Q2W096MN
Pfizer Central Research Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50422378 (CHEMBL122621) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Antagonist affinity [non competitive (irreversible)] at alpha-1D-adrenoreceptors on isolated thoracic aorta from rat				J Med Chem 44: 362-71 (2001) BindingDB Entry DOI: 10.7270/Q289175Q
University of Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50176526 (6-hydroxy-3-(3',5'-dihydroxyphenyl)coumarin \| CHEM...) Show SMILES Oc1ccc2oc(=O)c(cc2c1)-c1cc(O)cc(O)c1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Noradrenaline induced vasorelaxant activity in intact rat aortic rings				Bioorg Med Chem Lett 16: 257-61 (2005) Article DOI: 10.1016/j.bmcl.2005.10.013 BindingDB Entry DOI: 10.7270/Q2SQ8ZXQ
Universidad de Santiago de Compostela Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM23926 ((E)-resveratrol \| 5-[(E)-2-(4-hydroxyphenyl)etheny...) Show SMILES Oc1ccc(\C=C\c2cc(O)cc(O)c2)cc1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Noradrenaline induced vasorelaxant activity in intact rat aortic rings				Bioorg Med Chem Lett 16: 257-61 (2005) Article DOI: 10.1016/j.bmcl.2005.10.013 BindingDB Entry DOI: 10.7270/Q2SQ8ZXQ
Universidad de Santiago de Compostela Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50176525 (7-hydroxy-3-(3',5'-dihydroxyphenyl)coumarin \| CHEM...) Show SMILES Oc1ccc2cc(-c3cc(O)cc(O)c3)c(=O)oc2c1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.89E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Noradrenaline induced vasorelaxant activity in intact rat aortic rings				Bioorg Med Chem Lett 16: 257-61 (2005) Article DOI: 10.1016/j.bmcl.2005.10.013 BindingDB Entry DOI: 10.7270/Q2SQ8ZXQ
Universidad de Santiago de Compostela Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50176528 (3-(3,5-dimethoxyphenyl)-7-hydroxy-2H-chromen-2-one...) Show SMILES COc1cc(OC)cc(c1)-c1cc2ccc(O)cc2oc1=O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Noradrenaline induced vasorelaxant activity in intact rat aortic rings				Bioorg Med Chem Lett 16: 257-61 (2005) Article DOI: 10.1016/j.bmcl.2005.10.013 BindingDB Entry DOI: 10.7270/Q2SQ8ZXQ
Universidad de Santiago de Compostela Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50176523 (6-methoxy-3-(3',5'-dimethoxyphenyl)coumarin \| CHEM...) Show SMILES COc1ccc2oc(=O)c(cc2c1)-c1cc(OC)cc(OC)c1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Noradrenaline induced vasorelaxant activity in intact rat aortic rings				Bioorg Med Chem Lett 16: 257-61 (2005) Article DOI: 10.1016/j.bmcl.2005.10.013 BindingDB Entry DOI: 10.7270/Q2SQ8ZXQ
Universidad de Santiago de Compostela Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50176522 (7-methoxy-3-(3',5'-dimethoxyphenyl)coumarin \| CHEM...) Show SMILES COc1ccc2cc(-c3cc(OC)cc(OC)c3)c(=O)oc2c1 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Noradrenaline induced vasorelaxant activity in intact rat aortic rings				Bioorg Med Chem Lett 16: 257-61 (2005) Article DOI: 10.1016/j.bmcl.2005.10.013 BindingDB Entry DOI: 10.7270/Q2SQ8ZXQ
Universidad de Santiago de Compostela Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50176527 (6,8-dihydroxy-3-(3',5'-dihydroxyphenyl)coumarin \| ...) Show SMILES Oc1cc(O)cc(c1)-c1cc2cc(O)cc(O)c2oc1=O Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.55E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Noradrenaline induced vasorelaxant activity in intact rat aortic rings				Bioorg Med Chem Lett 16: 257-61 (2005) Article DOI: 10.1016/j.bmcl.2005.10.013 BindingDB Entry DOI: 10.7270/Q2SQ8ZXQ
Universidad de Santiago de Compostela Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Rattus norvegicus (Rat))	BDBM50176524 (6,8-dimethoxy-3-(3',5'-dimethoxyphenyl)coumarin \| ...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Noradrenaline induced vasorelaxant activity in intact rat aortic rings				Bioorg Med Chem Lett 16: 257-61 (2005) Article DOI: 10.1016/j.bmcl.2005.10.013 BindingDB Entry DOI: 10.7270/Q2SQ8ZXQ
Universidad de Santiago de Compostela Curated by ChEMBL					More data for this Ligand-Target Pair