Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175512 (US9119845, 13) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.11E+3 | n/a | 7.50E+3 | n/a | 2.20E+3 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175515 (US9119845, 16) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 440 | n/a | 1.07E+3 | n/a | 6.90E+3 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175511 (US9119845, 12) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.88E+3 | n/a | 9.36E+3 | n/a | 7.70E+3 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175502 (US9119845, 3) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.73E+4 | n/a | 4.17E+4 | n/a | 9.99E+3 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175507 (US9119845, 8) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 5.26E+3 | n/a | 1.27E+4 | n/a | 1.16E+4 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175524 (US9119845, 25) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.86E+4 | n/a | 4.50E+4 | n/a | 1.64E+4 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175522 (US9119845, 23) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 6.48E+3 | n/a | 1.56E+4 | n/a | 1.88E+4 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175523 (US9119845, 24) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 880 | n/a | 2.13E+3 | n/a | 3.05E+4 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175518 (US9119845, 19) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 8.02E+3 | n/a | 1.94E+4 | n/a | 3.50E+4 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175506 (US9119845, 7) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.88E+4 | n/a | 6.95E+4 | n/a | 4.64E+4 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175504 (US9119845, 5) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.48E+3 | n/a | 5.99E+3 | n/a | 6.07E+4 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175503 (US9119845, 4) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.66E+3 | n/a | 4.00E+3 | n/a | 6.30E+4 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175516 (US9119845, 17) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.16E+5 | n/a | 2.80E+5 | n/a | 6.56E+4 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175500 (US9119845, 1) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.48E+4 | n/a | 3.58E+4 | n/a | 6.59E+4 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175514 (US9119845, 15) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.04E+4 | n/a | 4.92E+4 | n/a | 6.83E+4 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175509 (US9119845, 10) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.12E+5 | n/a | 2.70E+5 | n/a | 7.06E+4 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175505 (US9119845, 6) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 8.30E+4 | n/a | 2.00E+5 | n/a | 1.15E+5 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175517 (US9119845, 18) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.14E+4 | n/a | 2.76E+4 | n/a | 1.39E+5 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175508 (US9119845, 9) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 5.37E+4 | n/a | 1.30E+5 | n/a | 1.45E+5 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Lysosomal acid glucosylceramidase (Mus musculus (Mouse)) | BDBM175501 (US9119845, 2) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 4.06E+5 | n/a | 9.80E+5 | n/a | 2.66E+5 | n/a | n/a | 4.5 | n/a |
Amicus Therapeautics, Inc. US Patent | Assay Description To 2.5 μl of supernatant (in 96-well plates) was added 17.5 μl reaction buffer (citrate phosphate buffer, pH 4.5, no Triton X-100), and 50 ... | US Patent US9119845 (2015) BindingDB Entry DOI: 10.7270/Q2V40T0P | |||||||||||
More data for this Ligand-Target Pair |