Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phospholipase D (Streptomyces chromofuscus) | BDBM123756 (1-methyl-3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]pyr...) | UniProtKB/SwissProt GoogleScholar AffyNet | DrugBank PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D (Streptomyces chromofuscus) | BDBM123754 (1-methyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyr...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D (Streptomyces chromofuscus) | BDBM50345704 (1-(tert-butyl)-3-(naphthalen-2-yl)-1H-pyrazolo[3,4...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D (Streptomyces chromofuscus) | BDBM50229961 (1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 65 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D (Streptomyces chromofuscus) | BDBM178081 (3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (17)) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 105 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D (Streptomyces chromofuscus) | BDBM178082 (3-(naphthalen-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D (Streptomyces chromofuscus) | BDBM123755 (1-methyl-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-am...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D (Streptomyces chromofuscus) | BDBM123745 (1-(4-methoxyphenyl)-3-(naphthalen-1-yl)-1H-pyrazol...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 125 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D (Streptomyces chromofuscus) | BDBM123746 (1-(4-methoxyphenyl)-3-phenyl-1H-pyrazolo[3,4-d]pyr...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D (Streptomyces chromofuscus) | BDBM123757 (1,3-dimethyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (...) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 150 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D (Streptomyces chromofuscus) | BDBM123747 (1-(tert-butyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrimidi...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 250 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D (Streptomyces chromofuscus) | BDBM123748 (1-(tert-butyl)-3-methyl-1H-pyrazolo[3,4-d]pyrimidi...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D (Streptomyces chromofuscus) | BDBM178083 (3-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine (19)) | UniProtKB/SwissProt GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 500 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D (Streptomyces chromofuscus) | BDBM123752 (3‐(naphthalen‐1‐yl)‐1̴...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 875 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D (Streptomyces chromofuscus) | BDBM123753 (3-methyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-am...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 900 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D (Streptomyces chromofuscus) | BDBM3003 (1,3-diphenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine |...) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.25E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D (Streptomyces chromofuscus) | BDBM123749 (1-(2-ethylphenyl)-3-(naphthalen-1-yl)-1H-pyrazolo[...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D (Streptomyces chromofuscus) | BDBM123751 (1-(2-ethylphenyl)-3-(naphthalen-2-yl)-1H-pyrazolo[...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.55E+4 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Phospholipase D (Streptomyces chromofuscus) | BDBM123750 (1-(2-ethylphenyl)-3-phenyl-1H-pyrazolo[3,4-d]pyrim...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Roxbury Community College | Assay Description A NaOH stock solution (50 mM) was standardized with KHP then diluted in Millipore water (10-fold serial dilutions) then used to hold the pH constant ... | Chem Biol Drug Des 87: 714-29 (2016) Article DOI: 10.1111/cbdd.12705 BindingDB Entry DOI: 10.7270/Q2R78D0V | |||||||||||
More data for this Ligand-Target Pair |