BindingDB PrimarySearch

Found 7 hits of ki data for polymerid = 7748
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Rattus norvegicus (Rat))	BDBM181109 (3-Mercaptopicolinic acid (MPA)) Show SMILES OC(=O)c1ncccc1S Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	3.70E+4	-6.04	n/a	n/a	n/a	n/a	n/a	n/a	25
The University of Kansas Medical Center					Assay Description OAA/PEP binding site. When the enzyme was assayed in the direction of PEP →OAA, the standard reaction mixture contained 50 mM HEPES (pH 7.5), 2...				Biochemistry 54: 5878-87 (2015) Article DOI: 10.1021/acs.biochem.5b00822 BindingDB Entry DOI: 10.7270/Q2M61J1Q
The University of Kansas Medical Center					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Rattus norvegicus (Rat))	BDBM181109 (3-Mercaptopicolinic acid (MPA)) Show SMILES OC(=O)c1ncccc1S Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	4.50E+4	-5.93	n/a	n/a	n/a	n/a	n/a	n/a	25
The University of Kansas Medical Center					Assay Description OAA/PEP binding site. The activity of PEPCK in the direction from OAA to PEP was assayed with 50 mM HEPES (pH 7.5), 10 mM DTT, 4 mM MgCl2, 0.5 mM GTP...				Biochemistry 54: 5878-87 (2015) Article DOI: 10.1021/acs.biochem.5b00822 BindingDB Entry DOI: 10.7270/Q2M61J1Q
The University of Kansas Medical Center					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Rattus norvegicus (Rat))	BDBM181109 (3-Mercaptopicolinic acid (MPA)) Show SMILES OC(=O)c1ncccc1S Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	8.30E+4	-5.56	n/a	n/a	n/a	n/a	n/a	n/a	25
The University of Kansas Medical Center					Assay Description Allosteric binding site. When the enzyme was assayed in the direction of PEP →OAA, the standard reaction mixture contained 50 mM HEPES (pH 7.5)...				Biochemistry 54: 5878-87 (2015) Article DOI: 10.1021/acs.biochem.5b00822 BindingDB Entry DOI: 10.7270/Q2M61J1Q
The University of Kansas Medical Center					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Rattus norvegicus (Rat))	BDBM181109 (3-Mercaptopicolinic acid (MPA)) Show SMILES OC(=O)c1ncccc1S Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	8.30E+4	-5.56	n/a	n/a	n/a	n/a	n/a	n/a	25
The University of Kansas Medical Center					Assay Description OAA/PEP binding site. When the enzyme was assayed in the direction of PEP →OAA, the standard reaction mixture contained 50 mM HEPES (pH 7.5), 2...				Biochemistry 54: 5878-87 (2015) Article DOI: 10.1021/acs.biochem.5b00822 BindingDB Entry DOI: 10.7270/Q2M61J1Q
The University of Kansas Medical Center					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Rattus norvegicus (Rat))	BDBM181109 (3-Mercaptopicolinic acid (MPA)) Show SMILES OC(=O)c1ncccc1S Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	1.21E+5	-5.34	n/a	n/a	n/a	n/a	n/a	n/a	25
The University of Kansas Medical Center					Assay Description Allosteric binding site. The activity of PEPCK in the direction from OAA to PEP was assayed with 50 mM HEPES (pH 7.5), 10 mM DTT, 4 mM MgCl2, 0.5 mM ...				Biochemistry 54: 5878-87 (2015) Article DOI: 10.1021/acs.biochem.5b00822 BindingDB Entry DOI: 10.7270/Q2M61J1Q
The University of Kansas Medical Center					More data for this Ligand-Target Pair				3D Structure (crystal)
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Rattus norvegicus (Rat))	BDBM223202 (β,γ-methyleneguanosine 5′-triphosp...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Waterloo					Assay Description The inhibition of H477R PEPCK by β-sulfopyruvate (βSP), oxalate, and GMPPCP was conducted in the direction of PEP synthesis (OAA → PE...				Biochemistry 56: 2106-2115 (2017) Article DOI: 10.1021/acs.biochem.7b00178 BindingDB Entry DOI: 10.7270/Q2D50KTV
University of Waterloo					More data for this Ligand-Target Pair
Phosphoenolpyruvate carboxykinase, cytosolic [GTP] (Rattus norvegicus (Rat))	BDBM181109 (3-Mercaptopicolinic acid (MPA)) Show SMILES OC(=O)c1ncccc1S Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	1.80E+5	-5.11	n/a	n/a	n/a	n/a	n/a	n/a	25
The University of Kansas Medical Center					Assay Description Allosteric binding site. When the enzyme was assayed in the direction of PEP →OAA, the standard reaction mixture contained 50 mM HEPES (pH 7.5)...				Biochemistry 54: 5878-87 (2015) Article DOI: 10.1021/acs.biochem.5b00822 BindingDB Entry DOI: 10.7270/Q2M61J1Q
The University of Kansas Medical Center					More data for this Ligand-Target Pair				3D Structure (crystal)