Compile Data Set for Download or QSAR

Found 164 hits of ki for UniProtKB: P34968   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50001775 ((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...) Show SMILES [#6]-c1nc2sccn2c(=O)c1-[#6]-[#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6](\c1ccc(F)cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	0.820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50046475 (4-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadec...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1C2CCC1c1c(C2)[nH]c2ccccc12 |TLB:11:12:17.18.19:15.14,THB:20:18:12:15.14,26:17:12:15.14| Show InChI InChI=1S/C23H23FN2O/c24-16-9-7-15(8-10-16)22(27)6-3-13-26-17-11-12-21(26)23-18-4-1-2-5-19(18)25-20(23)14-17/h1-2,4-5,7-10,17,21,25H,3,6,11-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50047457 (4-[9,16-diazatetracyclo[10.3.1.02,10.03,8]hexadeca...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1C2CCCC1c1c(C2)[nH]c2ccccc12 |TLB:11:12:18.19.20:16.14.15,THB:21:19:12:16.14.15,27:18:12:16.14.15| Show InChI InChI=1S/C24H25FN2O/c25-17-12-10-16(11-13-17)23(28)9-4-14-27-18-5-3-8-22(27)24-19-6-1-2-7-20(19)26-21(24)15-18/h1-2,6-7,10-13,18,22,26H,3-5,8-9,14-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50036648 ((7R,10S)-4-[5-fluoro-9,15-diazatetracyclo[10.2.1.0...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1C2CCC1c1c(C2)[nH]c2ccc(F)cc12 |TLB:11:12:17.18.19:15.14,THB:27:17:12:15.14,20:18:12:15.14| Show InChI InChI=1S/C23H22F2N2O/c24-15-5-3-14(4-6-15)22(28)2-1-11-27-17-8-10-21(27)23-18-12-16(25)7-9-19(18)26-20(23)13-17/h3-7,9,12,17,21,26H,1-2,8,10-11,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50047445 (1-(4-fluorophenyl)-4-[9-methyl-9,15-diazatetracycl...) Show SMILES Cn1c2CC3CCC(N3CCCC(=O)c3ccc(F)cc3)c2c2ccccc12 |TLB:9:8:21.2.3:6.5,1:2:8:6.5,22:21:8:6.5| Show InChI InChI=1S/C24H25FN2O/c1-26-20-6-3-2-5-19(20)24-21-13-12-18(15-22(24)26)27(21)14-4-7-23(28)16-8-10-17(25)11-9-16/h2-3,5-6,8-11,18,21H,4,7,12-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50047446 (4-{5-fluoro-9,16-diazatetracyclo[10.3.1.0^{2,10}.0...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1C2CCCC1c1c(C2)[nH]c2ccc(F)cc12 |TLB:11:12:18.19.20:16.14.15,THB:28:18:12:16.14.15,21:19:12:16.14.15| Show InChI InChI=1S/C24H24F2N2O/c25-16-8-6-15(7-9-16)23(29)5-2-12-28-18-3-1-4-22(28)24-19-13-17(26)10-11-20(19)27-21(24)14-18/h6-11,13,18,22,27H,1-5,12,14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50036647 ((7R,10S)-5-[9,15-diazatetracyclo[10.2.1.02,10.03,8...) Show SMILES Fc1ccc(cc1)C(=O)CCCCN1C2CCC1c1c(C2)[nH]c2ccccc12 |TLB:12:13:18.19.20:16.15,THB:21:19:13:16.15,27:18:13:16.15| Show InChI InChI=1S/C24H25FN2O/c25-17-10-8-16(9-11-17)23(28)7-3-4-14-27-18-12-13-22(27)24-19-5-1-2-6-20(19)26-21(24)15-18/h1-2,5-6,8-11,18,22,26H,3-4,7,12-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50047442 (5-[5-fluoro-9,15-diazatetracyclo[10.2.1.02,10.03,8...) Show SMILES Fc1ccc2[nH]c3CC4CCC(N4CCCCC(=O)c4ccccc4)c3c2c1 |TLB:13:12:25.6.7:10.9,26:25:12:10.9,5:6:12:10.9| Show InChI InChI=1S/C24H25FN2O/c25-17-9-11-20-19(14-17)24-21(26-20)15-18-10-12-22(24)27(18)13-5-4-8-23(28)16-6-2-1-3-7-16/h1-3,6-7,9,11,14,18,22,26H,4-5,8,10,12-13,15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002288 (1-(4-Fluoro-phenyl)-2-{1-[2-(4-trifluoromethyl-phe...) Show SMILES Fc1ccc(cc1)C(=O)CC1CCN(CCc2ccc(cc2)C(F)(F)F)CC1 Show InChI InChI=1S/C22H23F4NO/c23-20-7-3-18(4-8-20)21(28)15-17-10-13-27(14-11-17)12-9-16-1-5-19(6-2-16)22(24,25)26/h1-8,17H,9-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002213 (1-(4-Fluoro-phenyl)-2-{1-[2-(1H-indol-3-yl)-ethyl]...) Show SMILES Fc1ccc(cc1)C(=O)CC1CCN(CCc2c[nH]c3ccccc23)CC1 Show InChI InChI=1S/C23H25FN2O/c24-20-7-5-18(6-8-20)23(27)15-17-9-12-26(13-10-17)14-11-19-16-25-22-4-2-1-3-21(19)22/h1-8,16-17,25H,9-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002250 (1-(4-Fluoro-phenyl)-2-[1-(4-trifluoromethyl-benzyl...) Show SMILES Fc1ccc(cc1)C(=O)CC1CCN(Cc2ccc(cc2)C(F)(F)F)CC1 Show InChI InChI=1S/C21H21F4NO/c22-19-7-3-17(4-8-19)20(27)13-15-9-11-26(12-10-15)14-16-1-5-18(6-2-16)21(23,24)25/h1-8,15H,9-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50047440 (4-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadec...) Show SMILES O=C(CCCN1C2CCC1c1c(C2)[nH]c2ccccc12)c1ccccc1 |TLB:4:5:10.11.12:8.7,THB:13:11:5:8.7,19:10:5:8.7| Show InChI InChI=1S/C23H24N2O/c26-22(16-7-2-1-3-8-16)11-6-14-25-17-12-13-21(25)23-18-9-4-5-10-19(18)24-20(23)15-17/h1-5,7-10,17,21,24H,6,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50036649 ((7R,10S)-1-(6-fluorobenzo[d]isoxazol-3-yl)-4-[5-fl...) Show SMILES Fc1ccc2c(CCCCN3C4CCC3c3c(C4)[nH]c4ccc(F)cc34)noc2c1 |TLB:9:10:15.16.17:13.12,THB:25:15:10:13.12,18:16:10:13.12| Show InChI InChI=1S/C24H23F2N3O/c25-14-5-8-19-18(11-14)24-21(27-19)13-16-6-9-22(24)29(16)10-2-1-3-20-17-7-4-15(26)12-23(17)30-28-20/h4-5,7-8,11-12,16,22,27H,1-3,6,9-10,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002220 (1-(4-Fluoro-phenyl)-2-(1-phenethyl-piperidin-4-yl)...) Show SMILES Fc1ccc(cc1)C(=O)CC1CCN(CCc2ccccc2)CC1 Show InChI InChI=1S/C21H24FNO/c22-20-8-6-19(7-9-20)21(24)16-18-11-14-23(15-12-18)13-10-17-4-2-1-3-5-17/h1-9,18H,10-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002242 (2-{1-[2-(4-Chloro-phenyl)-ethyl]-piperidin-4-yl}-1...) Show SMILES Fc1ccc(cc1)C(=O)CC1CCN(CCc2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C21H23ClFNO/c22-19-5-1-16(2-6-19)9-12-24-13-10-17(11-14-24)15-21(25)18-3-7-20(23)8-4-18/h1-8,17H,9-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50036651 ((7R,10S)-1-(6-fluorobenzo[d]isoxazol-3-yl)-3-[5-fl...) Show SMILES Fc1ccc2c(CCCN3C4CCC3c3c(C4)[nH]c4ccc(F)cc34)noc2c1 |TLB:8:9:14.15.16:12.11,THB:24:14:9:12.11,17:15:9:12.11| Show InChI InChI=1S/C23H21F2N3O/c24-13-4-7-18-17(10-13)23-20(26-18)12-15-5-8-21(23)28(15)9-1-2-19-16-6-3-14(25)11-22(16)29-27-19/h3-4,6-7,10-11,15,21,26H,1-2,5,8-9,12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002207 (1-Cyclopropylmethyl-4-(4-fluoro-phenoxymethyl)-pip...) Show SMILES Fc1ccc(OCC2CCN(CC3CC3)CC2)cc1 Show InChI InChI=1S/C16H22FNO/c17-15-3-5-16(6-4-15)19-12-14-7-9-18(10-8-14)11-13-1-2-13/h3-6,13-14H,1-2,7-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Mus musculus (Mouse))	BDBM50060417 (5-Methyl-3,5-dihydro-2H-pyrrolo[2,3-f]indole-1-car...) Show SMILES Cn1ccc2cc3N(CCc3cc12)C(=O)Nc1cccnc1 Show InChI InChI=1S/C17H16N4O/c1-20-7-4-12-10-16-13(9-15(12)20)5-8-21(16)17(22)19-14-3-2-6-18-11-14/h2-4,6-7,9-11H,5,8H2,1H3,(H,19,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity analysed on 5-HT 2C in human clone using [3H]mesulergine as radioligand				J Med Chem 39: 2773-80 (1996) Article DOI: 10.1021/jm960062t BindingDB Entry DOI: 10.7270/Q2DZ09G0
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002198 (1-(4-Fluoro-phenyl)-2-{1-[2-(4-fluoro-phenyl)-ethy...) Show SMILES Fc1ccc(CCN2CCC(CC(=O)c3ccc(F)cc3)CC2)cc1 Show InChI InChI=1S/C21H23F2NO/c22-19-5-1-16(2-6-19)9-12-24-13-10-17(11-14-24)15-21(25)18-3-7-20(23)8-4-18/h1-8,17H,9-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Mus musculus (Mouse))	BDBM50017721 (1-Methyl-4-(5H-dibenzo(a,d)cycloheptenylidene)pipe...) Show SMILES [#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6]-1/c2ccccc2-[#6]=[#6]-c2ccccc-12 |c:16| Show InChI InChI=1S/C21H21N/c1-22-14-12-18(13-15-22)21-19-8-4-2-6-16(19)10-11-17-7-3-5-9-20(17)21/h2-11H,12-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affininity of the compound to 5-hydroxytryptamine 2C receptor using [3H]-Mesulergine as radioligand in stably transfected NIH3T3 cells				Bioorg Med Chem Lett 11: 655-8 (2001) BindingDB Entry DOI: 10.7270/Q2H994F8
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002298 (2-[1-(2-Cyclopropyl-ethyl)-piperidin-4-yl]-1-(4-fl...) Show SMILES Fc1ccc(cc1)C(=O)CC1CCN(CCC2CC2)CC1 Show InChI InChI=1S/C18H24FNO/c19-17-5-3-16(4-6-17)18(21)13-15-8-11-20(12-9-15)10-7-14-1-2-14/h3-6,14-15H,1-2,7-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50047437 (1-(6-fluorobenzo[d]isoxazol-3-yl)-3-[5-fluoro-9,16...) Show SMILES Fc1ccc2c(CCCN3C4CCCC3c3c(C4)[nH]c4ccc(F)cc34)noc2c1 |TLB:8:9:15.16.17:13.11.12,THB:25:15:9:13.11.12,18:16:9:13.11.12| Show InChI InChI=1S/C24H23F2N3O/c25-14-7-9-19-18(11-14)24-21(27-19)13-16-3-1-5-22(24)29(16)10-2-4-20-17-8-6-15(26)12-23(17)30-28-20/h6-9,11-12,16,22,27H,1-5,10,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002209 (1-(2,2-Dichloro-1-methyl-cyclopropylmethyl)-4-(4-f...) Show SMILES CC1(CN2CCC(COc3ccc(F)cc3)CC2)CC1(Cl)Cl Show InChI InChI=1S/C17H22Cl2FNO/c1-16(11-17(16,18)19)12-21-8-6-13(7-9-21)10-22-15-4-2-14(20)3-5-15/h2-5,13H,6-12H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002218 (2-(1-Cyclopropylmethyl-piperidin-4-yl)-1-(4-fluoro...) Show SMILES Fc1ccc(cc1)C(=O)CC1CCN(CC2CC2)CC1 Show InChI InChI=1S/C17H22FNO/c18-16-5-3-15(4-6-16)17(20)11-13-7-9-19(10-8-13)12-14-1-2-14/h3-6,13-14H,1-2,7-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50036650 ((7R,10S)-5-[5-fluoro-9,15-diazatetracyclo[10.2.1.0...) Show SMILES Fc1ccc(cc1)C(=O)CCCCN1C2CCC1c1c(C2)[nH]c2ccc(F)cc12 |TLB:12:13:18.19.20:16.15,THB:28:18:13:16.15,21:19:13:16.15| Show InChI InChI=1S/C24H24F2N2O/c25-16-6-4-15(5-7-16)23(29)3-1-2-12-28-18-9-11-22(28)24-19-13-17(26)8-10-20(19)27-21(24)14-18/h4-8,10,13,18,22,27H,1-3,9,11-12,14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002234 (1-(4-Fluoro-phenyl)-4-{4-[2-(4-fluoro-phenyl)-acet...) Show SMILES Fc1ccc(CC(=O)C2CCN(CCCC(=O)c3ccc(F)cc3)CC2)cc1 Show InChI InChI=1S/C23H25F2NO2/c24-20-7-3-17(4-8-20)16-23(28)19-11-14-26(15-12-19)13-1-2-22(27)18-5-9-21(25)10-6-18/h3-10,19H,1-2,11-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002254 (2-(1-Benzyl-piperidin-4-yl)-1-(4-fluoro-phenyl)-et...) Show SMILES Fc1ccc(cc1)C(=O)CC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H22FNO/c21-19-8-6-18(7-9-19)20(23)14-16-10-12-22(13-11-16)15-17-4-2-1-3-5-17/h1-9,16H,10-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50047449 (5-[9,16-diazatetracyclo[10.3.1.02,10.03,8]hexadeca...) Show SMILES O=C(CCCCN1C2CCCC1c1c(C2)[nH]c2ccccc12)c1ccccc1 |TLB:5:6:12.13.14:10.8.9,THB:15:13:6:10.8.9,21:12:6:10.8.9| Show InChI InChI=1S/C25H28N2O/c28-24(18-9-2-1-3-10-18)15-6-7-16-27-19-11-8-14-23(27)25-20-12-4-5-13-21(20)26-22(25)17-19/h1-5,9-10,12-13,19,23,26H,6-8,11,14-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50046479 (1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadec...) Show SMILES Fc1ccc(CCCCN2C3CCC2c2c(C3)[nH]c3ccccc23)cc1 |TLB:8:9:14.15.16:12.11,THB:17:15:9:12.11,23:14:9:12.11| Show InChI InChI=1S/C23H25FN2/c24-17-10-8-16(9-11-17)5-3-4-14-26-18-12-13-22(26)23-19-6-1-2-7-20(19)25-21(23)15-18/h1-2,6-11,18,22,25H,3-5,12-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002194 (4-(4-Fluoro-benzyloxymethyl)-1-phenethyl-piperidin...) Show SMILES Fc1ccc(COCC2CCN(CCc3ccccc3)CC2)cc1 Show InChI InChI=1S/C21H26FNO/c22-21-8-6-19(7-9-21)16-24-17-20-11-14-23(15-12-20)13-10-18-4-2-1-3-5-18/h1-9,20H,10-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002200 (4-(4-Fluoro-phenoxymethyl)-1-(2-methyl-cyclopropyl...) Show SMILES CC1CC1CN1CCC(COc2ccc(F)cc2)CC1 Show InChI InChI=1S/C17H24FNO/c1-13-10-15(13)11-19-8-6-14(7-9-19)12-20-17-4-2-16(18)3-5-17/h2-5,13-15H,6-12H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002301 (4-(4-Fluoro-benzyloxymethyl)-1-naphthalen-1-ylmeth...) Show SMILES Fc1ccc(COCC2CCN(Cc3cccc4ccccc34)CC2)cc1 Show InChI InChI=1S/C24H26FNO/c25-23-10-8-19(9-11-23)17-27-18-20-12-14-26(15-13-20)16-22-6-3-5-21-4-1-2-7-24(21)22/h1-11,20H,12-18H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50047450 (1-[9,16-diazatetracyclo[10.3.1.02,10.03,8]hexadeca...) Show SMILES Fc1ccc(CCCCN2C3CCCC2c2c(C3)[nH]c3ccccc23)cc1 |TLB:8:9:15.16.17:13.11.12,THB:18:16:9:13.11.12,24:15:9:13.11.12| Show InChI InChI=1S/C24H27FN2/c25-18-13-11-17(12-14-18)6-3-4-15-27-19-7-5-10-23(27)24-20-8-1-2-9-21(20)26-22(24)16-19/h1-2,8-9,11-14,19,23,26H,3-7,10,15-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002217 (2-[1-(4-Fluoro-benzyl)-piperidin-4-yl]-1-(4-fluoro...) Show SMILES Fc1ccc(CN2CCC(CC(=O)c3ccc(F)cc3)CC2)cc1 Show InChI InChI=1S/C20H21F2NO/c21-18-5-1-16(2-6-18)14-23-11-9-15(10-12-23)13-20(24)17-3-7-19(22)8-4-17/h1-8,15H,9-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002221 (1-[2-(4-Chloro-phenyl)-ethyl]-4-(4-fluoro-phenoxym...) Show SMILES Fc1ccc(OCC2CCN(CCc3ccc(Cl)cc3)CC2)cc1 Show InChI InChI=1S/C20H23ClFNO/c21-18-3-1-16(2-4-18)9-12-23-13-10-17(11-14-23)15-24-20-7-5-19(22)6-8-20/h1-8,17H,9-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50047452 (4-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadec...) Show SMILES O=C(CCCN1C2CCC1c1c(C2)[nH]c2ccccc12)c1cccs1 |TLB:4:5:10.11.12:8.7,THB:13:11:5:8.7,19:10:5:8.7| Show InChI InChI=1S/C21H22N2OS/c24-19(20-8-4-12-25-20)7-3-11-23-14-9-10-18(23)21-15-5-1-2-6-16(15)22-17(21)13-14/h1-2,4-6,8,12,14,18,22H,3,7,9-11,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002252 (1-Benzyl-4-(4-fluoro-phenoxymethyl)-piperidine; hy...) Show SMILES Fc1ccc(OCC2CCN(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C19H22FNO/c20-18-6-8-19(9-7-18)22-15-17-10-12-21(13-11-17)14-16-4-2-1-3-5-16/h1-9,17H,10-15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002236 (4-[4-(4-Fluoro-phenoxymethyl)-piperidin-1-ylmethyl...) Show SMILES Fc1ccc(OCC2CCN(Cc3ccncc3)CC2)cc1 Show InChI InChI=1S/C18H21FN2O/c19-17-1-3-18(4-2-17)22-14-16-7-11-21(12-8-16)13-15-5-9-20-10-6-15/h1-6,9-10,16H,7-8,11-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002260 (1-Cyclopropylmethyl-4-(2,4-dichloro-phenoxymethyl)...) Show SMILES Clc1ccc(OCC2CCN(CC3CC3)CC2)c(Cl)c1 Show InChI InChI=1S/C16H21Cl2NO/c17-14-3-4-16(15(18)9-14)20-11-13-5-7-19(8-6-13)10-12-1-2-12/h3-4,9,12-13H,1-2,5-8,10-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002269 (1-(4-Fluoro-benzyl)-4-(4-fluoro-phenoxymethyl)-pip...) Show SMILES Fc1ccc(CN2CCC(COc3ccc(F)cc3)CC2)cc1 Show InChI InChI=1S/C19H21F2NO/c20-17-3-1-15(2-4-17)13-22-11-9-16(10-12-22)14-23-19-7-5-18(21)6-8-19/h1-8,16H,9-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002293 (4-(4-Chloro-phenoxymethyl)-1-cyclopropylmethyl-pip...) Show SMILES Clc1ccc(OCC2CCN(CC3CC3)CC2)cc1 Show InChI InChI=1S/C16H22ClNO/c17-15-3-5-16(6-4-15)19-12-14-7-9-18(10-8-14)11-13-1-2-13/h3-6,13-14H,1-2,7-12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002303 (1-Cyclopropylmethyl-4-(3,4-difluoro-phenoxymethyl)...) Show SMILES Fc1ccc(OCC2CCN(CC3CC3)CC2)cc1F Show InChI InChI=1S/C16H21F2NO/c17-15-4-3-14(9-16(15)18)20-11-13-5-7-19(8-6-13)10-12-1-2-12/h3-4,9,12-13H,1-2,5-8,10-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002265 (2-(4-Fluoro-phenyl)-1-[1-(3-phenyl-propyl)-piperid...) Show SMILES OC(Cc1ccc(F)cc1)C1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C22H28FNO/c23-21-10-8-19(9-11-21)17-22(25)20-12-15-24(16-13-20)14-4-7-18-5-2-1-3-6-18/h1-3,5-6,8-11,20,22,25H,4,7,12-17H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Mus musculus (Mouse))	BDBM35920 (9,10-dihydroanthracene(DHA), 1a | 9-(Aminomethyl)-...) Show SMILES NCC1c2ccccc2Cc2ccccc12 Show InChI InChI=1S/C15H15N/c16-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)15/h1-8,15H,9-10,16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity to 5-hydroxytryptamine 2C receptor using [3H]Mesulergine as radioligand in stably transfected NIH3T3 cells				Bioorg Med Chem Lett 11: 655-8 (2001) BindingDB Entry DOI: 10.7270/Q2H994F8
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002204 (1-Benzyl-4-(biphenyl-4-ylmethoxymethyl)-piperidine...) Show SMILES C(OCc1ccc(cc1)-c1ccccc1)C1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C26H29NO/c1-3-7-22(8-4-1)19-27-17-15-24(16-18-27)21-28-20-23-11-13-26(14-12-23)25-9-5-2-6-10-25/h1-14,24H,15-21H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002216 (1-(2-Cyclopropyl-ethyl)-4-(4-fluoro-phenylsulfanyl...) Show SMILES Fc1ccc(SCC2CCN(CCC3CC3)CC2)cc1 Show InChI InChI=1S/C17H24FNS/c18-16-3-5-17(6-4-16)20-13-15-8-11-19(12-9-15)10-7-14-1-2-14/h3-6,14-15H,1-2,7-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description The compound was tested in vitro for its binding affinity towards 5-hydroxytryptamine 2 receptor				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002196 (1-Cyclopropylmethyl-4-phenoxymethyl-piperidine | C...) Show SMILES C(Oc1ccccc1)C1CCN(CC2CC2)CC1 Show InChI InChI=1S/C16H23NO/c1-2-4-16(5-3-1)18-13-15-8-10-17(11-9-15)12-14-6-7-14/h1-5,14-15H,6-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50002284 (1-Benzyl-4-(4-methoxy-phenoxymethyl)-piperidine | ...) Show SMILES COc1ccc(OCC2CCN(Cc3ccccc3)CC2)cc1 Show InChI InChI=1S/C20H25NO2/c1-22-19-7-9-20(10-8-19)23-16-18-11-13-21(14-12-18)15-17-5-3-2-4-6-17/h2-10,18H,11-16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Du Pont Merck Pharmaceutical Company Curated by ChEMBL					Assay Description In vitro binding affinity for serotonin 5-hydroxytryptamine (5-HT) 2 receptors				J Med Chem 35: 4344-61 (1992) BindingDB Entry DOI: 10.7270/Q28P614G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A/2B/2C (Mus musculus (Mouse))	BDBM50046482 (1-[9,15-diazatetracyclo[10.2.1.02,10.03,8]pentadec...) Show SMILES C(CCc1ccccc1)CN1C2CCC1c1c(C2)[nH]c2ccccc12 |TLB:9:10:15.16.17:13.12,THB:18:16:10:13.12,24:15:10:13.12| Show InChI InChI=1S/C23H26N2/c1-2-8-17(9-3-1)10-6-7-15-25-18-13-14-22(25)23-19-11-4-5-12-20(19)24-21(23)16-18/h1-5,8-9,11-12,18,22,24H,6-7,10,13-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Scios Nova Inc. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2 receptor from rat cortical synaptosomal membrane using radioligand [3H]ketanserin.				J Med Chem 36: 1488-95 (1993) BindingDB Entry DOI: 10.7270/Q2KD1X0K
					More data for this Ligand-Target Pair

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