Compile Data Set for Download or QSAR

Found 216 hits of ic50 for UniProtKB: P11166   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50155671 (CHEMBL3780239) Show SMILES COc1ccc(F)cc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C22H21FN6O/c1-30-20-8-7-16(23)13-19(20)27-9-11-28(12-10-27)21-18-14-26-29(22(18)25-15-24-21)17-5-3-2-4-6-17/h2-8,13-15H,9-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50514308 (CHEMBL4448899) Show SMILES Cc1c(NC(=O)c2cc(nc3cc(F)ccc23)C(N)=O)c(nn1Cc1ccc(cc1)C#N)C(F)(F)F Show InChI InChI=1S/C24H16F4N6O2/c1-12-20(21(24(26,27)28)33-34(12)11-14-4-2-13(10-29)3-5-14)32-23(36)17-9-19(22(30)35)31-18-8-15(25)6-7-16(17)18/h2-9H,11H2,1H3,(H2,30,35)(H,32,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as glucose uptake by measuring ATP incubated for 15 mins by CellTiter-Glo Luminescent Cell...				J Med Chem 63: 3834-3867 (2020) Article DOI: 10.1021/acs.jmedchem.9b01237 BindingDB Entry DOI: 10.7270/Q26113PD
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50152749 (CHEMBL3781913) Show SMILES COc1ccccc1N1CCCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C23H24N6O/c1-30-21-11-6-5-10-20(21)27-12-7-13-28(15-14-27)22-19-16-26-29(23(19)25-17-24-22)18-8-3-2-4-9-18/h2-6,8-11,16-17H,7,12-15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50155656 (CHEMBL3781331) Show SMILES COc1ccc(cc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1)C(N)=O Show InChI InChI=1S/C23H23N7O2/c1-32-20-8-7-16(21(24)31)13-19(20)28-9-11-29(12-10-28)22-18-14-27-30(23(18)26-15-25-22)17-5-3-2-4-6-17/h2-8,13-15H,9-12H2,1H3,(H2,24,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50152824 (CHEMBL3781548) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1F Show InChI InChI=1S/C22H21FN6O/c1-30-20-9-5-4-8-19(20)27-10-12-28(13-11-27)21-16-14-26-29(22(16)25-15-24-21)18-7-3-2-6-17(18)23/h2-9,14-15H,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50155715 (CHEMBL3781149) Show SMILES Oc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C26H28Br2ClN5O/c27-19-12-18-6-5-17-13-20(29)14-21(28)23(17)25(24(18)32-15-19)34-10-2-1-4-22(34)26(35)31-7-3-9-33-11-8-30-16-33/h8,11-16,22,25H,1-7,9-10H2,(H,31,35)/t22-,25?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50155751 (CHEMBL3780460) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1cc(F)cc(F)c1 Show InChI InChI=1S/C22H20F2N6O/c1-31-20-5-3-2-4-19(20)28-6-8-29(9-7-28)21-18-13-27-30(22(18)26-14-25-21)17-11-15(23)10-16(24)12-17/h2-5,10-14H,6-9H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50155585 (CHEMBL3780372) Show SMILES COc1ccncc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C21H21N7O/c1-29-19-7-8-22-14-18(19)26-9-11-27(12-10-26)20-17-13-25-28(21(17)24-15-23-20)16-5-3-2-4-6-16/h2-8,13-15H,9-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50152826 (CHEMBL3781347) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1C Show InChI InChI=1S/C23H24N6O/c1-17-7-3-4-8-19(17)29-23-18(15-26-29)22(24-16-25-23)28-13-11-27(12-14-28)20-9-5-6-10-21(20)30-2/h3-10,15-16H,11-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50155673 (CHEMBL3780972) Show SMILES COc1cc(F)ccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C22H21FN6O/c1-30-20-13-16(23)7-8-19(20)27-9-11-28(12-10-27)21-18-14-26-29(22(18)25-15-24-21)17-5-3-2-4-6-17/h2-8,13-15H,9-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50152743 (CHEMBL3781308) Show SMILES COc1ccccc1N1CCN(CC1C)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C23H24N6O/c1-17-15-27(12-13-28(17)20-10-6-7-11-21(20)30-2)22-19-14-26-29(23(19)25-16-24-22)18-8-4-3-5-9-18/h3-11,14,16-17H,12-13,15H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50155746 (CHEMBL3781151) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccc(F)cc1 Show InChI InChI=1S/C22H21FN6O/c1-30-20-5-3-2-4-19(20)27-10-12-28(13-11-27)21-18-14-26-29(22(18)25-15-24-21)17-8-6-16(23)7-9-17/h2-9,14-15H,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50155747 (CHEMBL3781194) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccc(cc1)C#N Show InChI InChI=1S/C23H21N7O/c1-31-21-5-3-2-4-20(21)28-10-12-29(13-11-28)22-19-15-27-30(23(19)26-16-25-22)18-8-6-17(14-24)7-9-18/h2-9,15-16H,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50155670 (CHEMBL3780144) Show SMILES COc1ccc(cc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1)C#N Show InChI InChI=1S/C23H21N7O/c1-31-21-8-7-17(14-24)13-20(21)28-9-11-29(12-10-28)22-19-15-27-30(23(19)26-16-25-22)18-5-3-2-4-6-18/h2-8,13,15-16H,9-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50155714 (CHEMBL3781157) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C26H25Br2ClN4O/c27-19-10-18-7-6-17-11-20(29)12-21(28)23(17)25(24(18)31-15-19)33-9-2-1-5-22(33)26(34)32-14-16-4-3-8-30-13-16/h3-4,8,10-13,15,22,25H,1-2,5-7,9,14H2,(H,32,34)/t22-,25?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50152776 (CHEMBL3780785) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(cnc12)-c1ccccc1 Show InChI InChI=1S/C22H22N6O/c1-29-19-10-6-5-9-18(19)26-11-13-27(14-12-26)21-20-22(24-15-23-21)28(16-25-20)17-7-3-2-4-8-17/h2-10,15-16H,11-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50155753 (CHEMBL3780470) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1cc(F)ccc1OC Show InChI InChI=1S/C23H23FN6O2/c1-31-20-6-4-3-5-18(20)28-9-11-29(12-10-28)22-17-14-27-30(23(17)26-15-25-22)19-13-16(24)7-8-21(19)32-2/h3-8,13-15H,9-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50155677 (CHEMBL3780765) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1cccc(c1)C#N Show InChI InChI=1S/C23H21N7O/c1-31-21-8-3-2-7-20(21)28-9-11-29(12-10-28)22-19-15-27-30(23(19)26-16-25-22)18-6-4-5-17(13-18)14-24/h2-8,13,15-16H,9-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50152827 (CHEMBL3781741) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1cccc(F)c1 Show InChI InChI=1S/C22H21FN6O/c1-30-20-8-3-2-7-19(20)27-9-11-28(12-10-27)21-18-14-26-29(22(18)25-15-24-21)17-6-4-5-16(23)13-17/h2-8,13-15H,9-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453265 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-7,8-dih...) Show SMILES CC(C)(C)NC(=O)COc1cccc(c1)-c1nc2CCOCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C28H30N6O3/c1-28(2,3)34-25(35)17-37-22-6-4-5-19(13-22)26-32-24-11-12-36-16-23(24)27(33-26)31-21-9-7-18(8-10-21)20-14-29-30-15-20/h4-10,13-15H,11-12,16-17H2,1-3H3,(H,29,30)(H,34,35)(H,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453246 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-5,7-dih...) Show SMILES CCC(C)(C)NC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C28H30N6O3/c1-4-28(2,3)34-25(35)17-37-22-7-5-6-19(12-22)26-32-24-16-36-15-23(24)27(33-26)31-21-10-8-18(9-11-21)20-13-29-30-14-20/h5-14H,4,15-17H2,1-3H3,(H,29,30)(H,34,35)(H,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50155680 (CHEMBL3780717) Show SMILES N#Cc1cccc(c1)N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1 Show InChI InChI=1S/C22H19N7/c23-14-17-5-4-8-19(13-17)27-9-11-28(12-10-27)21-20-15-26-29(22(20)25-16-24-21)18-6-2-1-3-7-18/h1-8,13,15-16H,9-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50155752 (CHEMBL3780527) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)C1CCCC1 Show InChI InChI=1S/C21H26N6O/c1-28-19-9-5-4-8-18(19)25-10-12-26(13-11-25)20-17-14-24-27(16-6-2-3-7-16)21(17)23-15-22-20/h4-5,8-9,14-16H,2-3,6-7,10-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453264 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-7,8-dih...) Show SMILES CCC(CC)NC(=O)COc1cccc(c1)-c1nc2CCOCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C29H32N6O3/c1-3-22(4-2)32-27(36)18-38-24-7-5-6-20(14-24)28-34-26-12-13-37-17-25(26)29(35-28)33-23-10-8-19(9-11-23)21-15-30-31-16-21/h5-11,14-16,22H,3-4,12-13,17-18H2,1-2H3,(H,30,31)(H,32,36)(H,33,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50152774 (CHEMBL3781384) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(nnc12)-c1ccccc1 Show InChI InChI=1S/C168H254N44O52/c1-17-89(10)137(165(260)188-93(14)144(239)197-118(72-99-75-180-104-38-25-24-37-102(99)104)155(250)199-114(68-86(4)5)156(251)208-135(87(6)7)163(258)196-106(40-26-29-58-169)146(241)181-77-125(221)189-107(42-32-61-179-168(174)175)150(245)191-105(140(173)235)39-28-31-60-177-128(224)83-264-66-65-263-64-62-178-124(220)57-63-212-129(225)52-53-130(212)226)210-157(252)116(69-96-33-20-18-21-34-96)200-152(247)112(50-56-133(231)232)195-151(246)108(41-27-30-59-170)192-142(237)91(12)185-141(236)90(11)187-149(244)111(47-51-123(172)219)190-126(222)78-182-148(243)110(49-55-132(229)230)194-153(248)113(67-85(2)3)198-154(249)115(71-98-43-45-101(218)46-44-98)201-160(255)120(80-213)204-162(257)122(82-215)205-164(259)136(88(8)9)209-159(254)119(74-134(233)234)202-161(256)121(81-214)206-167(262)139(95(16)217)211-158(253)117(70-97-35-22-19-23-36-97)203-166(261)138(94(15)216)207-127(223)79-183-147(242)109(48-54-131(227)228)193-143(238)92(13)186-145(240)103(171)73-100-76-176-84-184-100/h18-25,33-38,43-46,52-53,75-76,84-95,103,105-122,135-139,180,213-218H,17,26-32,39-42,47-51,54-74,77-83,169-171H2,1-16H3,(H2,172,219)(H2,173,235)(H,176,184)(H,177,224)(H,178,220)(H,181,241)(H,182,243)(H,183,242)(H,185,236)(H,186,240)(H,187,244)(H,188,260)(H,189,221)(H,190,222)(H,191,245)(H,192,237)(H,193,238)(H,194,248)(H,195,246)(H,196,258)(H,197,239)(H,198,249)(H,199,250)(H,200,247)(H,201,255)(H,202,256)(H,203,261)(H,204,257)(H,205,259)(H,206,262)(H,207,223)(H,208,251)(H,209,254)(H,210,252)(H,211,253)(H,227,228)(H,229,230)(H,231,232)(H,233,234)(H4,174,175,179)/t89-,90-,91-,92-,93-,94+,95+,103-,105?,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,135-,136-,137-,138-,139-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50155745 (CHEMBL3780043) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1cccc(C)c1 Show InChI InChI=1S/C23H24N6O/c1-17-6-5-7-18(14-17)29-23-19(15-26-29)22(24-16-25-23)28-12-10-27(11-13-28)20-8-3-4-9-21(20)30-2/h3-9,14-16H,10-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50152825 (CHEMBL3780235) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(ncc12)-c1ccccc1OC Show InChI InChI=1S/C23H24N6O2/c1-30-20-9-5-3-7-18(20)27-11-13-28(14-12-27)22-17-15-26-29(23(17)25-16-24-22)19-8-4-6-10-21(19)31-2/h3-10,15-16H,11-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50514308 (CHEMBL4448899) Show SMILES Cc1c(NC(=O)c2cc(nc3cc(F)ccc23)C(N)=O)c(nn1Cc1ccc(cc1)C#N)C(F)(F)F Show InChI InChI=1S/C24H16F4N6O2/c1-12-20(21(24(26,27)28)33-34(12)11-14-4-2-13(10-29)3-5-14)32-23(36)17-9-19(22(30)35)31-18-8-15(25)6-7-16(17)18/h2-9H,11H2,1H3,(H2,30,35)(H,32,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Kadmon Corporation, LLC. Curated by ChEMBL					Assay Description Inhibition of GLUT1 in human wild-type DLD1 cells assessed as reduction in ATP level measured after 90 mins by Celltiter-glo luminescent assay				J Med Chem 63: 5201-5211 (2020) Article DOI: 10.1021/acs.jmedchem.9b02153 BindingDB Entry DOI: 10.7270/Q2GH9NGP
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM50152823 (CHEMBL3780054) Show SMILES COc1ccccc1N1CCN(CC1)c1ncnc2n(-c3ccccc3)c(=O)[nH]c12 Show InChI InChI=1S/C22H22N6O2/c1-30-18-10-6-5-9-17(18)26-11-13-27(14-12-26)20-19-21(24-15-23-20)28(22(29)25-19)16-7-3-2-4-8-16/h2-10,15H,11-14H2,1H3,(H,25,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Pharma AG Curated by ChEMBL					Assay Description Inhibition of human GLUT1 expressed in DLD1 cells assessed as ATP production co-incubated with 100 mM glucose for 16 hrs by CellTiter-Glo assay in pr...				Bioorg Med Chem Lett 26: 1732-7 (2016) Article DOI: 10.1016/j.bmcl.2016.02.050 BindingDB Entry DOI: 10.7270/Q2639RM3
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453216 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-6-isobu...) Show SMILES CC(C)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C(=O)C(C)C Show InChI InChI=1S/C31H35N7O3/c1-19(2)31(40)38-13-12-27-26(17-38)30(35-24-10-8-21(9-11-24)23-15-32-33-16-23)37-29(36-27)22-6-5-7-25(14-22)41-18-28(39)34-20(3)4/h5-11,14-16,19-20H,12-13,17-18H2,1-4H3,(H,32,33)(H,34,39)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453222 (US10729691, Example 7) Show SMILES O=C(COc1cccc(c1)-c1nc(Nc2ccc(cc2)-c2cn[nH]c2)c2sccc2n1)NC1CCCC1 Show InChI InChI=1S/C28H26N6O2S/c35-25(31-21-5-1-2-6-21)17-36-23-7-3-4-19(14-23)27-33-24-12-13-37-26(24)28(34-27)32-22-10-8-18(9-11-22)20-15-29-30-16-20/h3-4,7-16,21H,1-2,5-6,17H2,(H,29,30)(H,31,35)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453227 (US10729691, Example 12) Show SMILES O=C(COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)NC1CCC1 Show InChI InChI=1S/C27H26N6O3/c34-25(30-20-4-2-5-20)16-36-22-6-1-3-18(11-22)26-32-24-15-35-14-23(24)27(33-26)31-21-9-7-17(8-10-21)19-12-28-29-13-19/h1,3,6-13,20H,2,4-5,14-16H2,(H,28,29)(H,30,34)(H,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453228 (US10729691, Example 13) Show SMILES O=C(COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)NC1CCCC1 Show InChI InChI=1S/C28H28N6O3/c35-26(31-21-5-1-2-6-21)17-37-23-7-3-4-19(12-23)27-33-25-16-36-15-24(25)28(34-27)32-22-10-8-18(9-11-22)20-13-29-30-14-20/h3-4,7-14,21H,1-2,5-6,15-17H2,(H,29,30)(H,31,35)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453234 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)pyrido[3...) Show SMILES CC(C)NC(=O)COc1cccc(c1)-c1nc(Nc2ccc(cc2)-c2cn[nH]c2)c2ccncc2n1 Show InChI InChI=1S/C27H25N7O2/c1-17(2)31-25(35)16-36-22-5-3-4-19(12-22)26-33-24-15-28-11-10-23(24)27(34-26)32-21-8-6-18(7-9-21)20-13-29-30-14-20/h3-15,17H,16H2,1-2H3,(H,29,30)(H,31,35)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453235 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)pyrido[3...) Show SMILES O=C(COc1cccc(c1)-c1nc(Nc2ccc(cc2)-c2cn[nH]c2)c2ccncc2n1)NC1CCC1 Show InChI InChI=1S/C28H25N7O2/c36-26(32-21-4-2-5-21)17-37-23-6-1-3-19(13-23)27-34-25-16-29-12-11-24(25)28(35-27)33-22-9-7-18(8-10-22)20-14-30-31-15-20/h1,3,6-16,21H,2,4-5,17H2,(H,30,31)(H,32,36)(H,33,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453236 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)pyrido[3...) Show SMILES O=C(COc1cccc(c1)-c1nc(Nc2ccc(cc2)-c2cn[nH]c2)c2ccncc2n1)NC1CCCC1 Show InChI InChI=1S/C29H27N7O2/c37-27(33-22-5-1-2-6-22)18-38-24-7-3-4-20(14-24)28-35-26-17-30-13-12-25(26)29(36-28)34-23-10-8-19(9-11-23)21-15-31-32-16-21/h3-4,7-17,22H,1-2,5-6,18H2,(H,31,32)(H,33,37)(H,34,35,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453241 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-5,7-dih...) Show SMILES CC(C)(C)NC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C27H28N6O3/c1-27(2,3)33-24(34)16-36-21-6-4-5-18(11-21)25-31-23-15-35-14-22(23)26(32-25)30-20-9-7-17(8-10-20)19-12-28-29-13-19/h4-13H,14-16H2,1-3H3,(H,28,29)(H,33,34)(H,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453242 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-5,7-dih...) Show SMILES CCC(CC)NC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C28H30N6O3/c1-3-21(4-2)31-26(35)17-37-23-7-5-6-19(12-23)27-33-25-16-36-15-24(25)28(34-27)32-22-10-8-18(9-11-22)20-13-29-30-14-20/h5-14,21H,3-4,15-17H2,1-2H3,(H,29,30)(H,31,35)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453243 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-5,7-dih...) Show SMILES CCC(C)NC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453244 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-5,7-dih...) Show SMILES CC(C)CNC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C27H28N6O3/c1-17(2)11-28-25(34)16-36-22-5-3-4-19(10-22)26-32-24-15-35-14-23(24)27(33-26)31-21-8-6-18(7-9-21)20-12-29-30-13-20/h3-10,12-13,17H,11,14-16H2,1-2H3,(H,28,34)(H,29,30)(H,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453245 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-5,7-dih...) Show SMILES CC(C)(C)CNC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C28H30N6O3/c1-28(2,3)17-29-25(35)16-37-22-6-4-5-19(11-22)26-33-24-15-36-14-23(24)27(34-26)32-21-9-7-18(8-10-21)20-12-30-31-13-20/h4-13H,14-17H2,1-3H3,(H,29,35)(H,30,31)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453246 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-5,7-dih...) Show SMILES CCC(C)(C)NC(=O)COc1cccc(c1)-c1nc2COCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C28H30N6O3/c1-4-28(2,3)34-25(35)17-37-22-7-5-6-19(12-22)26-32-24-16-36-15-23(24)27(33-26)31-21-10-8-18(9-11-21)20-13-29-30-14-20/h5-14H,4,15-17H2,1-3H3,(H,29,30)(H,34,35)(H,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453255 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-7,8-dih...) Show SMILES CC(C)NC(=O)COc1cccc(c1)-c1nc2CCOCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C27H28N6O3/c1-17(2)30-25(34)16-36-22-5-3-4-19(12-22)26-32-24-10-11-35-15-23(24)27(33-26)31-21-8-6-18(7-9-21)20-13-28-29-14-20/h3-9,12-14,17H,10-11,15-16H2,1-2H3,(H,28,29)(H,30,34)(H,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453256 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-7,8-dih...) Show SMILES CCC(C)NC(=O)COc1cccc(c1)-c1nc2CCOCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453260 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-6-acety...) Show SMILES CCC(CC)NC(=O)COc1cccc(c1)-c1nc2CCN(Cc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1)C(C)=O Show InChI InChI=1S/C31H35N7O3/c1-4-24(5-2)34-29(40)19-41-26-8-6-7-22(15-26)30-36-28-13-14-38(20(3)39)18-27(28)31(37-30)35-25-11-9-21(10-12-25)23-16-32-33-17-23/h6-12,15-17,24H,4-5,13-14,18-19H2,1-3H3,(H,32,33)(H,34,40)(H,35,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453261 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-7,8-dih...) Show SMILES CC(C)CNC(=O)COc1cccc(c1)-c1nc2CCOCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C28H30N6O3/c1-18(2)13-29-26(35)17-37-23-5-3-4-20(12-23)27-33-25-10-11-36-16-24(25)28(34-27)32-22-8-6-19(7-9-22)21-14-30-31-15-21/h3-9,12,14-15,18H,10-11,13,16-17H2,1-2H3,(H,29,35)(H,30,31)(H,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453262 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-7,8-dih...) Show SMILES CC(C)(C)CNC(=O)COc1cccc(c1)-c1nc2CCOCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C29H32N6O3/c1-29(2,3)18-30-26(36)17-38-23-6-4-5-20(13-23)27-34-25-11-12-37-16-24(25)28(35-27)33-22-9-7-19(8-10-22)21-14-31-32-15-21/h4-10,13-15H,11-12,16-18H2,1-3H3,(H,30,36)(H,31,32)(H,33,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453263 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-6-acety...) Show SMILES CC(=O)N1CCc2nc(nc(Nc3ccc(cc3)-c3cn[nH]c3)c2C1)-c1cccc(OCC(=O)NC(C)(C)C)c1 Show InChI InChI=1S/C30H33N7O3/c1-19(38)37-13-12-26-25(17-37)29(33-23-10-8-20(9-11-23)22-15-31-32-16-22)35-28(34-26)21-6-5-7-24(14-21)40-18-27(39)36-30(2,3)4/h5-11,14-16H,12-13,17-18H2,1-4H3,(H,31,32)(H,36,39)(H,33,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453264 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-7,8-dih...) Show SMILES CCC(CC)NC(=O)COc1cccc(c1)-c1nc2CCOCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C29H32N6O3/c1-3-22(4-2)32-27(36)18-38-24-7-5-6-20(14-24)28-34-26-12-13-37-17-25(26)29(35-28)33-23-10-8-19(9-11-23)21-15-30-31-16-21/h5-11,14-16,22H,3-4,12-13,17-18H2,1-2H3,(H,30,31)(H,32,36)(H,33,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair
Solute carrier family 2, facilitated glucose transporter member 1 (Homo sapiens (Human))	BDBM453265 (2-(3-(4-((4-(1H-pyrazol-4-yl)phenyl)amino)-7,8-dih...) Show SMILES CC(C)(C)NC(=O)COc1cccc(c1)-c1nc2CCOCc2c(Nc2ccc(cc2)-c2cn[nH]c2)n1 Show InChI InChI=1S/C28H30N6O3/c1-28(2,3)34-25(35)17-37-22-6-4-5-19(13-22)26-32-24-11-12-36-16-23(24)27(33-26)31-21-9-7-18(8-10-21)20-14-29-30-15-20/h4-10,13-15H,11-12,16-17H2,1-3H3,(H,29,30)(H,34,35)(H,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
KADMON CORPORATION, LLC US Patent					Assay Description HT1080 cells (as well as other cell types) were plated to confluency in 96-well plates. Cells were exposed to the combination of 10 μM Oligomyci...				US Patent US10729691 (2020) BindingDB Entry DOI: 10.7270/Q2417142
					More data for this Ligand-Target Pair

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