Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-galactosidase (Escherichia coli (Enterobacteria)) | BDBM50182795 (5-(dimethylamino)-N-(6-((2R,3S,4R,5S)-3,4,5-trihyd...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of Escherichia coli beta-galactosidase assessed as inhibition of nitrophenolate release by spectrophotometry | Bioorg Med Chem Lett 21: 6872-5 (2011) Article DOI: 10.1016/j.bmcl.2011.09.012 BindingDB Entry DOI: 10.7270/Q24B31RQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Escherichia coli (Enterobacteria)) | BDBM50356096 (CHEMBL1911831) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Industrial Research Limited Curated by ChEMBL | Assay Description Inhibition of Escherichia coli beta-galactosidase assessed as inhibition of nitrophenolate release by spectrophotometry | Bioorg Med Chem Lett 21: 6872-5 (2011) Article DOI: 10.1016/j.bmcl.2011.09.012 BindingDB Entry DOI: 10.7270/Q24B31RQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Escherichia coli (Enterobacteria)) | BDBM192767 (β-gal inhibitor, 13) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.00E+3 | -7.66 | n/a | n/a | n/a | n/a | n/a | n/a | 30 |
Fairfield University | Assay Description Enzymatic activity of beta-galactosidase from Escherichia coli (1.2 x 10^-10 M) was measured using the colorimetric substrate ortho-nitrophenyl-b-g... | Chembiochem 17: 1602-5 (2016) Article DOI: 10.1002/cbic.201600267 BindingDB Entry DOI: 10.7270/Q2Q23Z2F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Escherichia coli (Enterobacteria)) | BDBM192768 (β-gal inhibitor, 14) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 3.90E+3 | -7.50 | n/a | n/a | n/a | n/a | n/a | n/a | 30 |
Fairfield University | Assay Description Enzymatic activity of beta-galactosidase from Escherichia coli (1.2 x 10^-10 M) was measured using the colorimetric substrate ortho-nitrophenyl-b-g... | Chembiochem 17: 1602-5 (2016) Article DOI: 10.1002/cbic.201600267 BindingDB Entry DOI: 10.7270/Q2Q23Z2F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Escherichia coli (Enterobacteria)) | BDBM50375511 (CHEMBL406973) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Seville Curated by ChEMBL | Assay Description Inhibition of Escherichia coli beta-galactosidase using o-nitrophenyl beta-D-galactopyranoside after 10 to 30 mins by spectrophotometric method | Eur J Med Chem 121: 880-891 (2016) Article DOI: 10.1016/j.ejmech.2015.08.038 BindingDB Entry DOI: 10.7270/Q2FT8P07 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Escherichia coli (Enterobacteria)) | BDBM192769 (β-gal inhibitor, 15) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | 5.90E+3 | -7.25 | n/a | n/a | n/a | n/a | n/a | n/a | 30 |
Fairfield University | Assay Description Enzymatic activity of beta-galactosidase from Escherichia coli (1.2 x 10^-10 M) was measured using the colorimetric substrate ortho-nitrophenyl-b-g... | Chembiochem 17: 1602-5 (2016) Article DOI: 10.1002/cbic.201600267 BindingDB Entry DOI: 10.7270/Q2Q23Z2F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-galactosidase (Escherichia coli (Enterobacteria)) | BDBM192770 (IPTG) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 7.60E+4 | -5.71 | n/a | n/a | n/a | n/a | n/a | n/a | 30 |
Fairfield University | Assay Description Enzymatic activity of beta-galactosidase from Escherichia coli (1.2 x 10^-10 M) was measured using the colorimetric substrate ortho-nitrophenyl-b-g... | Chembiochem 17: 1602-5 (2016) Article DOI: 10.1002/cbic.201600267 BindingDB Entry DOI: 10.7270/Q2Q23Z2F | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |