Compile Data Set for Download or QSAR

Found 500 hits of ic50 data for polymerid = 8157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-glucuronidase (Homo sapiens (Human))	BDBM229595 (US9334288, 9) Show SMILES C1CCc2c(C1)c(nc1sc3c(nnnc3c21)N1CCNCC1)N1CCOCC1 Show InChI InChI=1S/C20H25N7OS/c1-2-4-14-13(3-1)15-16-17(19(24-25-23-16)26-7-5-21-6-8-26)29-20(15)22-18(14)27-9-11-28-12-10-27/h21H,1-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	n/a	n/a	0.984	n/a	n/a	n/a	n/a	n/a	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description PheG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb...				US Patent US9334288 (2016) BindingDB Entry DOI: 10.7270/Q270809V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316366 (US9617239, BRITE-354972) Show SMILES Cc1ccc(Oc2ccc(s2)S(=O)(=O)NCc2cccc3ccccc23)cc1 Show InChI InChI=1S/C22H19NO3S2/c1-16-9-11-19(12-10-16)26-21-13-14-22(27-21)28(24,25)23-15-18-7-4-6-17-5-2-3-8-20(17)18/h2-14,23H,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM229595 (US9334288, 9) Show SMILES C1CCc2c(C1)c(nc1sc3c(nnnc3c21)N1CCNCC1)N1CCOCC1 Show InChI InChI=1S/C20H25N7OS/c1-2-4-14-13(3-1)15-16-17(19(24-25-23-16)26-7-5-21-6-8-26)29-20(15)22-18(14)27-9-11-28-12-10-27/h21H,1-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	US Patent	n/a	n/a	1.17	n/a	n/a	n/a	n/a	n/a	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description PNPG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb...				US Patent US9334288 (2016) BindingDB Entry DOI: 10.7270/Q270809V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM229595 (US9334288, 9) Show SMILES C1CCc2c(C1)c(nc1sc3c(nnnc3c21)N1CCNCC1)N1CCOCC1 Show InChI InChI=1S/C20H25N7OS/c1-2-4-14-13(3-1)15-16-17(19(24-25-23-16)26-7-5-21-6-8-26)29-20(15)22-18(14)27-9-11-28-12-10-27/h21H,1-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
University of KwaZulu-Natal Curated by ChEMBL					Assay Description Inhibition of beta-glucuronidase (unknown origin)				Eur J Med Chem 187: (2020) Article DOI: 10.1016/j.ejmech.2019.111921 BindingDB Entry DOI: 10.7270/Q29W0K1V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	CHEMBL5273557 Show SMILES OCCC[n+]1ccc(\C=C\c2cccc3ccccc23)cc1 Show InChI InChI=1S/C20H20NO/c22-16-4-13-21-14-11-17(12-15-21)9-10-19-7-3-6-18-5-1-2-8-20(18)19/h1-3,5-12,14-15,22H,4,13,16H2/q+1/b10-9+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL CHEMBL PC cid PC sid UniChem Similars		n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vitro concentration required to inhibit partially purified dihydropteroate synthase of Escherichia coli by 50%				Citation and Details
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316368 (US9617239, BRITE-355252) Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCc1cccc2ccccc12 Show InChI InChI=1S/C25H24ClN3O3S2/c26-23-16-24(34(30,31)28-17-19-7-3-6-18-5-1-2-10-22(18)19)33-25(23)32-21-9-4-8-20(15-21)29-13-11-27-12-14-29/h1-10,15-16,27-28H,11-14,17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
University of KwaZulu-Natal Curated by ChEMBL					Assay Description Inhibition of beta-glucuronidase (unknown origin)				Eur J Med Chem 187: (2020) Article DOI: 10.1016/j.ejmech.2019.111921 BindingDB Entry DOI: 10.7270/Q29W0K1V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316459 (US9617239, BRITE-492802) Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCc1ccc(Cl)cc1 Show InChI InChI=1S/C21H21Cl2N3O3S2/c22-16-6-4-15(5-7-16)14-25-31(27,28)20-13-19(23)21(30-20)29-18-3-1-2-17(12-18)26-10-8-24-9-11-26/h1-7,12-13,24-25H,8-11,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316467 (US9617239, BRITE-492808) Show SMILES Cc1cccc(CNS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)c1 Show InChI InChI=1S/C22H24ClN3O3S2/c1-16-4-2-5-17(12-16)15-25-31(27,28)21-14-20(23)22(30-21)29-19-7-3-6-18(13-19)26-10-8-24-9-11-26/h2-7,12-14,24-25H,8-11,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316461 (US9617239, BRITE-492805) Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCc1ccccc1Cl Show InChI InChI=1S/C21H21Cl2N3O3S2/c22-18-7-2-1-4-15(18)14-25-31(27,28)20-13-19(23)21(30-20)29-17-6-3-5-16(12-17)26-10-8-24-9-11-26/h1-7,12-13,24-25H,8-11,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316468 (US9617239, BRITE-492809) Show SMILES Fc1cccc(CNS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)c1 Show InChI InChI=1S/C21H21ClFN3O3S2/c22-19-13-20(31(27,28)25-14-15-3-1-4-16(23)11-15)30-21(19)29-18-6-2-5-17(12-18)26-9-7-24-8-10-26/h1-6,11-13,24-25H,7-10,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50019283 (CHEMBL3289121) Show SMILES CCOc1ccccc1-c1nc2ccccc2c(=O)[nH]1 Show InChI InChI=1S/C16H14N2O2/c1-2-20-14-10-6-4-8-12(14)15-17-13-9-5-3-7-11(13)16(19)18-15/h3-10H,2H2,1H3,(H,17,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
University of KwaZulu-Natal Curated by ChEMBL					Assay Description Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-d-glucuronide as substrate after 30 mins				Eur J Med Chem 187: (2020) Article DOI: 10.1016/j.ejmech.2019.111921 BindingDB Entry DOI: 10.7270/Q29W0K1V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316457 (US9617239, BRITE-492800) Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C20H19Cl2N3O3S2/c21-14-3-1-4-15(11-14)24-30(26,27)19-13-18(22)20(29-19)28-17-6-2-5-16(12-17)25-9-7-23-8-10-25/h1-6,11-13,23-24H,7-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316456 (US9617239, BRITE-492799) Show SMILES COc1cccc(NS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)c1 Show InChI InChI=1S/C21H22ClN3O4S2/c1-28-17-6-2-4-15(12-17)24-31(26,27)20-14-19(22)21(30-20)29-18-7-3-5-16(13-18)25-10-8-23-9-11-25/h2-7,12-14,23-24H,8-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316454 (US9617239, BRITE-492797) Show SMILES O=S(=O)(NCc1cccc2ccccc12)c1ccc(Oc2cccc(c2)N2CCNCC2)s1 Show InChI InChI=1S/C25H25N3O3S2/c29-33(30,27-18-20-7-3-6-19-5-1-2-10-23(19)20)25-12-11-24(32-25)31-22-9-4-8-21(17-22)28-15-13-26-14-16-28/h1-12,17,26-27H,13-16,18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316368 (US9617239, BRITE-355252) Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCc1cccc2ccccc12 Show InChI InChI=1S/C25H24ClN3O3S2/c26-23-16-24(34(30,31)28-17-19-7-3-6-18-5-1-2-10-22(18)19)33-25(23)32-21-9-4-8-20(15-21)29-13-11-27-12-14-29/h1-10,15-16,27-28H,11-14,17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316367 (US9617239, BRITE-355123) Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCc1cccc(Cl)c1 Show InChI InChI=1S/C21H21Cl2N3O3S2/c22-16-4-1-3-15(11-16)14-25-31(27,28)20-13-19(23)21(30-20)29-18-6-2-5-17(12-18)26-9-7-24-8-10-26/h1-6,11-13,24-25H,7-10,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284071 (CHEMBL4165927) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cc(O)c(O)cc1O)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cc(O)c(O)cc1O Show InChI InChI=1S/C40H32N6O8/c1-20-2-4-21(5-3-20)38(28-18-41-30-8-6-22(10-26(28)30)39(53)45-43-16-24-12-34(49)36(51)14-32(24)47)29-19-42-31-9-7-23(11-27(29)31)40(54)46-44-17-25-13-35(50)37(52)15-33(25)48/h2-19,38,41-42,47-52H,1H3,(H,45,53)(H,46,54)/b43-16+,44-17+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM193719 (2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(2-fluoro...) Show SMILES Fc1ccccc1NC(=S)NNC(=O)c1ccc(cc1)C(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C31H24FN5OS/c32-25-9-3-6-12-28(25)35-31(39)37-36-30(38)20-15-13-19(14-16-20)29(23-17-33-26-10-4-1-7-21(23)26)24-18-34-27-11-5-2-8-22(24)27/h1-18,29,33-34H,(H,36,38)(H2,35,37,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Teknologi MARA					Assay Description β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...				Bioorg Chem 68: 56-63 (2016) Article DOI: 10.1016/j.bioorg.2016.07.008 BindingDB Entry DOI: 10.7270/Q2RV0MGS
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM193719 (2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(2-fluoro...) Show SMILES Fc1ccccc1NC(=S)NNC(=O)c1ccc(cc1)C(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 Show InChI InChI=1S/C31H24FN5OS/c32-25-9-3-6-12-28(25)35-31(39)37-36-30(38)20-15-13-19(14-16-20)29(23-17-33-26-10-4-1-7-21(23)26)24-18-34-27-11-5-2-8-22(24)27/h1-18,29,33-34H,(H,36,38)(H2,35,37,39)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
University of KwaZulu-Natal Curated by ChEMBL					Assay Description Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-d-glucuronide as substrate after 30 mins				Eur J Med Chem 187: (2020) Article DOI: 10.1016/j.ejmech.2019.111921 BindingDB Entry DOI: 10.7270/Q29W0K1V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316460 (US9617239, BRITE-492803) Show SMILES COc1ccc(CNS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)cc1 Show InChI InChI=1S/C22H24ClN3O4S2/c1-29-18-7-5-16(6-8-18)15-25-32(27,28)21-14-20(23)22(31-21)30-19-4-2-3-17(13-19)26-11-9-24-10-12-26/h2-8,13-14,24-25H,9-12,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284029 (CHEMBL4168635) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cccc(O)c1O)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cccc(O)c1O Show InChI InChI=1S/C40H32N6O6/c1-22-8-10-23(11-9-22)36(30-20-41-32-14-12-24(16-28(30)32)39(51)45-43-18-26-4-2-6-34(47)37(26)49)31-21-42-33-15-13-25(17-29(31)33)40(52)46-44-19-27-5-3-7-35(48)38(27)50/h2-21,36,41-42,47-50H,1H3,(H,45,51)(H,46,52)/b43-18+,44-19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50541002 (CHEMBL4642420) Show SMILES Cc1cc(C)c2[nH]c(=O)c(CN(CCO)C(=O)Nc3ccccc3C)cc2c1 Show InChI InChI=1S/C22H25N3O3/c1-14-10-16(3)20-17(11-14)12-18(21(27)24-20)13-25(8-9-26)22(28)23-19-7-5-4-6-15(19)2/h4-7,10-12,26H,8-9,13H2,1-3H3,(H,23,28)(H,24,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
University of KwaZulu-Natal Curated by ChEMBL					Assay Description Inhibition of beta-glucuronidase (unknown origin)				Eur J Med Chem 187: (2020) Article DOI: 10.1016/j.ejmech.2019.111921 BindingDB Entry DOI: 10.7270/Q29W0K1V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316453 (US9617239, BRITE-492796) Show SMILES CN(Cc1cccc2ccccc12)S(=O)(=O)c1cc(Cl)c(Oc2cccc(c2)N2CCNCC2)s1 Show InChI InChI=1S/C26H26ClN3O3S2/c1-29(18-20-8-4-7-19-6-2-3-11-23(19)20)35(31,32)25-17-24(27)26(34-25)33-22-10-5-9-21(16-22)30-14-12-28-13-15-30/h2-11,16-17,28H,12-15,18H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM193734 (2-(4-(di(1H-indol-3-yl)methyl)benzoyl)-N-(4(triflu...) Show SMILES FC(F)(F)c1ccc(NC(=S)NNC(=O)c2ccc(cc2)C(c2c[nH]c3ccccc23)c2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C32H24F3N5OS/c33-32(34,35)21-13-15-22(16-14-21)38-31(42)40-39-30(41)20-11-9-19(10-12-20)29(25-17-36-27-7-3-1-5-23(25)27)26-18-37-28-8-4-2-6-24(26)28/h1-18,29,36-37H,(H,39,41)(H2,38,40,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
University of KwaZulu-Natal Curated by ChEMBL					Assay Description Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-d-glucuronide as substrate after 30 mins				Eur J Med Chem 187: (2020) Article DOI: 10.1016/j.ejmech.2019.111921 BindingDB Entry DOI: 10.7270/Q29W0K1V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316369 (US9617239, BRITE-354975) Show SMILES O=S(=O)(NCCN1CCCC1)c1ccc(Oc2cccc(c2)N2CCNCC2)s1 Show InChI InChI=1S/C20H28N4O3S2/c25-29(26,22-10-13-23-11-1-2-12-23)20-7-6-19(28-20)27-18-5-3-4-17(16-18)24-14-8-21-9-15-24/h3-7,16,21-22H,1-2,8-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM193733 (2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(3,4-dich...) Show SMILES Clc1ccc(NC(=S)NNC(=O)c2ccc(cc2)C(c2c[nH]c3ccccc23)c2c[nH]c3ccccc23)cc1Cl Show InChI InChI=1S/C31H23Cl2N5OS/c32-25-14-13-20(15-26(25)33)36-31(40)38-37-30(39)19-11-9-18(10-12-19)29(23-16-34-27-7-3-1-5-21(23)27)24-17-35-28-8-4-2-6-22(24)28/h1-17,29,34-35H,(H,37,39)(H2,36,38,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Teknologi MARA					Assay Description β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...				Bioorg Chem 68: 56-63 (2016) Article DOI: 10.1016/j.bioorg.2016.07.008 BindingDB Entry DOI: 10.7270/Q2RV0MGS
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316466 (US9617239, BRITE-492807) Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCc1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C21H20Cl3N3O3S2/c22-15-8-14(9-16(23)10-15)13-26-32(28,29)20-12-19(24)21(31-20)30-18-3-1-2-17(11-18)27-6-4-25-5-7-27/h1-3,8-12,25-26H,4-7,13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50541003 (CHEMBL4641808) Show SMILES Cc1cc(C)c2[nH]c(=O)c(CN(CCO)C(=O)Nc3ccc(F)cc3C)cc2c1 Show InChI InChI=1S/C22H24FN3O3/c1-13-8-15(3)20-16(9-13)11-17(21(28)25-20)12-26(6-7-27)22(29)24-19-5-4-18(23)10-14(19)2/h4-5,8-11,27H,6-7,12H2,1-3H3,(H,24,29)(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	142	n/a	n/a	n/a	n/a	n/a	n/a
University of KwaZulu-Natal Curated by ChEMBL					Assay Description Inhibition of beta-glucuronidase (unknown origin)				Eur J Med Chem 187: (2020) Article DOI: 10.1016/j.ejmech.2019.111921 BindingDB Entry DOI: 10.7270/Q29W0K1V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316370 (US9617239, BRITE-354989) Show SMILES CN(C)CCCNS(=O)(=O)c1ccc(Oc2cccc(c2)N2CCNCC2)s1 Show InChI InChI=1S/C19H28N4O3S2/c1-22(2)12-4-9-21-28(24,25)19-8-7-18(27-19)26-17-6-3-5-16(15-17)23-13-10-20-11-14-23/h3,5-8,15,20-21H,4,9-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316371 (US9617239, BRITE-354909) Show SMILES COc1ccc(NS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)cc1 Show InChI InChI=1S/C21H22ClN3O4S2/c1-28-17-7-5-15(6-8-17)24-31(26,27)20-14-19(22)21(30-20)29-18-4-2-3-16(13-18)25-11-9-23-10-12-25/h2-8,13-14,23-24H,9-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316372 (US9617239, BRITE-354725) Show SMILES COc1ccc(CCNS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)cc1OC Show InChI InChI=1S/C24H28ClN3O5S2/c1-31-21-7-6-17(14-22(21)32-2)8-9-27-35(29,30)23-16-20(25)24(34-23)33-19-5-3-4-18(15-19)28-12-10-26-11-13-28/h3-7,14-16,26-27H,8-13H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM193733 (2-(4-(Di(1H-indol-3-yl)methyl)benzoyl)-N-(3,4-dich...) Show SMILES Clc1ccc(NC(=S)NNC(=O)c2ccc(cc2)C(c2c[nH]c3ccccc23)c2c[nH]c3ccccc23)cc1Cl Show InChI InChI=1S/C31H23Cl2N5OS/c32-25-14-13-20(15-26(25)33)36-31(40)38-37-30(39)19-11-9-18(10-12-19)29(23-16-34-27-7-3-1-5-21(23)27)24-17-35-28-8-4-2-6-22(24)28/h1-17,29,34-35H,(H,37,39)(H2,36,38,40)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
University of KwaZulu-Natal Curated by ChEMBL					Assay Description Inhibition of beta-glucuronidase (unknown origin) using p-nitrophenyl-beta-d-glucuronide as substrate after 30 mins				Eur J Med Chem 187: (2020) Article DOI: 10.1016/j.ejmech.2019.111921 BindingDB Entry DOI: 10.7270/Q29W0K1V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284055 (CHEMBL4177204) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1c(O)cc(O)cc1O)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1c(O)cc(O)cc1O Show InChI InChI=1S/C40H32N6O8/c1-20-2-4-21(5-3-20)38(28-16-41-32-8-6-22(10-26(28)32)39(53)45-43-18-30-34(49)12-24(47)13-35(30)50)29-17-42-33-9-7-23(11-27(29)33)40(54)46-44-19-31-36(51)14-25(48)15-37(31)52/h2-19,38,41-42,47-52H,1H3,(H,45,53)(H,46,54)/b43-18+,44-19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316373 (US9617239, BRITE-354969) Show SMILES CCN(CCNS(=O)(=O)c1ccc(Oc2cccc(c2)N2CCNCC2)s1)c1cccc(C)c1 Show InChI InChI=1S/C25H32N4O3S2/c1-3-28(21-7-4-6-20(2)18-21)17-14-27-34(30,31)25-11-10-24(33-25)32-23-9-5-8-22(19-23)29-15-12-26-13-16-29/h4-11,18-19,26-27H,3,12-17H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM193734 (2-(4-(di(1H-indol-3-yl)methyl)benzoyl)-N-(4(triflu...) Show SMILES FC(F)(F)c1ccc(NC(=S)NNC(=O)c2ccc(cc2)C(c2c[nH]c3ccccc23)c2c[nH]c3ccccc23)cc1 Show InChI InChI=1S/C32H24F3N5OS/c33-32(34,35)21-13-15-22(16-14-21)38-31(42)40-39-30(41)20-11-9-19(10-12-20)29(25-17-36-27-7-3-1-5-23(25)27)26-18-37-28-8-4-2-6-24(26)28/h1-18,29,36-37H,(H,39,41)(H2,38,40,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Teknologi MARA					Assay Description β-Glucuronidase activity was determined by measuring the absorbance at 405 nm of p-nitrophenol formed from the substrate by the spectrophotometr...				Bioorg Chem 68: 56-63 (2016) Article DOI: 10.1016/j.bioorg.2016.07.008 BindingDB Entry DOI: 10.7270/Q2RV0MGS
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316374 (US9617239, BRITE-355417) Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCc1ccccc1Br Show InChI InChI=1S/C21H21BrClN3O3S2/c22-18-7-2-1-4-15(18)14-25-31(27,28)20-13-19(23)21(30-20)29-17-6-3-5-16(12-17)26-10-8-24-9-11-26/h1-7,12-13,24-25H,8-11,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316375 (US9617239, BRITE-355006) Show SMILES Cc1ccc(CNS(=O)(=O)c2ccc(Oc3cccc(c3)N3CCNCC3)s2)c(C)c1 Show InChI InChI=1S/C23H27N3O3S2/c1-17-6-7-19(18(2)14-17)16-25-31(27,28)23-9-8-22(30-23)29-21-5-3-4-20(15-21)26-12-10-24-11-13-26/h3-9,14-15,24-25H,10-13,16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM163640 (5,11Dimethyl3(piperazin1yl)8thia4,6diazatricyclo[7...) Show SMILES CC1CCc2c(C1)sc1nc(C)nc(N3CCNCC3)c21 Show InChI InChI=1S/C16H22N4S/c1-10-3-4-12-13(9-10)21-16-14(12)15(18-11(2)19-16)20-7-5-17-6-8-20/h10,17H,3-9H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	213	n/a	n/a	n/a	n/a	n/a	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description PheG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb...				US Patent US9334288 (2016) BindingDB Entry DOI: 10.7270/Q270809V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316376 (US9617239, BRITE-355017) Show SMILES O=S(=O)(NCc1ccc2OCOc2c1)c1ccc(Oc2cccc(c2)N2CCNCC2)s1 Show InChI InChI=1S/C22H23N3O5S2/c26-32(27,24-14-16-4-5-19-20(12-16)29-15-28-19)22-7-6-21(31-22)30-18-3-1-2-17(13-18)25-10-8-23-9-11-25/h1-7,12-13,23-24H,8-11,14-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316377 (US9617239, BRITE-354979) Show SMILES COc1ccc(NS(=O)(=O)c2ccc(Oc3cccc(c3)N3CCNCC3)s2)cc1 Show InChI InChI=1S/C21H23N3O4S2/c1-27-18-7-5-16(6-8-18)23-30(25,26)21-10-9-20(29-21)28-19-4-2-3-17(15-19)24-13-11-22-12-14-24/h2-10,15,22-23H,11-14H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM163640 (5,11Dimethyl3(piperazin1yl)8thia4,6diazatricyclo[7...) Show SMILES CC1CCc2c(C1)sc1nc(C)nc(N3CCNCC3)c21 Show InChI InChI=1S/C16H22N4S/c1-10-3-4-12-13(9-10)21-16-14(12)15(18-11(2)19-16)20-7-5-17-6-8-20/h10,17H,3-9H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	231	n/a	n/a	n/a	n/a	n/a	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description PNPG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb...				US Patent US9334288 (2016) BindingDB Entry DOI: 10.7270/Q270809V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316378 (US9617239, BRITE-355004) Show SMILES Clc1ccc(CCNS(=O)(=O)c2ccc(Oc3cccc(c3)N3CCNCC3)s2)cc1 Show InChI InChI=1S/C22H24ClN3O3S2/c23-18-6-4-17(5-7-18)10-11-25-31(27,28)22-9-8-21(30-22)29-20-3-1-2-19(16-20)26-14-12-24-13-15-26/h1-9,16,24-25H,10-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316379 (US9617239, BRITE-354667) Show SMILES Fc1ccccc1CCNS(=O)(=O)c1cc(Cl)c(Oc2cccc(c2)N2CCNCC2)s1 Show InChI InChI=1S/C22H23ClFN3O3S2/c23-19-15-21(32(28,29)26-9-8-16-4-1-2-7-20(16)24)31-22(19)30-18-6-3-5-17(14-18)27-12-10-25-11-13-27/h1-7,14-15,25-26H,8-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316380 (US9617239, BRITE-354966) Show SMILES O=S(=O)(NCC1CCCCC1)c1ccc(Oc2cccc(c2)N2CCNCC2)s1 Show InChI InChI=1S/C21H29N3O3S2/c25-29(26,23-16-17-5-2-1-3-6-17)21-10-9-20(28-21)27-19-8-4-7-18(15-19)24-13-11-22-12-14-24/h4,7-10,15,17,22-23H,1-3,5-6,11-14,16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM163636 (3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...) Show SMILES CCOc1ccc(NC(=S)N(CCO)Cc2cc3cc(C)cc(C)c3[nH]c2=O)cc1 Show InChI InChI=1S/C23H27N3O3S/c1-4-29-20-7-5-19(6-8-20)24-23(30)26(9-10-27)14-18-13-17-12-15(2)11-16(3)21(17)25-22(18)28/h5-8,11-13,27H,4,9-10,14H2,1-3H3,(H,24,30)(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	277	n/a	n/a	n/a	n/a	n/a	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description PheG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb...				US Patent US9334288 (2016) BindingDB Entry DOI: 10.7270/Q270809V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM163636 (3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...) Show SMILES CCOc1ccc(NC(=S)N(CCO)Cc2cc3cc(C)cc(C)c3[nH]c2=O)cc1 Show InChI InChI=1S/C23H27N3O3S/c1-4-29-20-7-5-19(6-8-20)24-23(30)26(9-10-27)14-18-13-17-12-15(2)11-16(3)21(17)25-22(18)28/h5-8,11-13,27H,4,9-10,14H2,1-3H3,(H,24,30)(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
University of KwaZulu-Natal Curated by ChEMBL					Assay Description Inhibition of beta-glucuronidase (unknown origin)				Eur J Med Chem 187: (2020) Article DOI: 10.1016/j.ejmech.2019.111921 BindingDB Entry DOI: 10.7270/Q29W0K1V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316381 (US9617239, BRITE-355262) Show SMILES Clc1cc(sc1Oc1cccc(c1)N1CCNCC1)S(=O)(=O)NCc1ccccc1 Show InChI InChI=1S/C21H22ClN3O3S2/c22-19-14-20(30(26,27)24-15-16-5-2-1-3-6-16)29-21(19)28-18-8-4-7-17(13-18)25-11-9-23-10-12-25/h1-8,13-14,23-24H,9-12,15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM163636 (3[(6,8Dimethyl2oxo1,2dihydroquinolin3 yl)methyl]1(...) Show SMILES CCOc1ccc(NC(=S)N(CCO)Cc2cc3cc(C)cc(C)c3[nH]c2=O)cc1 Show InChI InChI=1S/C23H27N3O3S/c1-4-29-20-7-5-19(6-8-20)24-23(30)26(9-10-27)14-18-13-17-12-15(2)11-16(3)21(17)25-22(18)28/h5-8,11-13,27H,4,9-10,14H2,1-3H3,(H,24,30)(H,25,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	283	n/a	n/a	n/a	n/a	n/a	n/a
The University of North Carolina at Chapel Hill US Patent					Assay Description PNPG Assay: Two ß-glucuronidase activity assays were employed to examine the potency of inhibitors both in vitro and in cell-based studies. An absorb...				US Patent US9334288 (2016) BindingDB Entry DOI: 10.7270/Q270809V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316383 (US9617239, BRITE-354873) Show SMILES FC(F)(F)c1cccc(CNS(=O)(=O)c2cc(Cl)c(Oc3cccc(c3)N3CCNCC3)s2)c1 Show InChI InChI=1S/C22H21ClF3N3O3S2/c23-19-13-20(34(30,31)28-14-15-3-1-4-16(11-15)22(24,25)26)33-21(19)32-18-6-2-5-17(12-18)29-9-7-27-8-10-29/h1-6,11-13,27-28H,7-10,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM316382 (US9617239, BRITE-354965) Show SMILES COc1ccc(CNS(=O)(=O)c2ccc(Oc3cccc(c3)N3CCNCC3)s2)cc1OC Show InChI InChI=1S/C23H27N3O5S2/c1-29-20-7-6-17(14-21(20)30-2)16-25-33(27,28)23-9-8-22(32-23)31-19-5-3-4-18(15-19)26-12-10-24-11-13-26/h3-9,14-15,24-25H,10-13,16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
North Carolina Central University; The University of North Carolina at Chapel Hill US Patent					Assay Description The β-glucuronidase assay was performed by the addition of 0.5 μl of compound (or DMSO) to the well of a black 384-well plate followed by t...				US Patent US9617239 (2017) BindingDB Entry DOI: 10.7270/Q22B913V
					More data for this Ligand-Target Pair

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