Compile Data Set for Download or QSAR

Found 153 hits of ec50 for UniProtKB: P35400   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283487 (CHEMBL4162576) Show SMILES Clc1ccc(Oc2ccc(NC(=O)c3ccccn3)cc2Cl)nc1 Show InChI InChI=1S/C17H11Cl2N3O2/c18-11-4-7-16(21-10-11)24-15-6-5-12(9-13(15)19)22-17(23)14-3-1-2-8-20-14/h1-10H,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	146	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283478 (CHEMBL4164141) Show SMILES COc1cc(F)c(cc1Cl)-c1c(C)nn2c(cc(C)nc12)C(F)(F)F |(37.17,-44.14,;38.18,-42.98,;37.7,-41.52,;38.73,-40.37,;38.23,-38.91,;39.26,-37.76,;36.73,-38.6,;35.71,-39.75,;36.19,-41.21,;35.16,-42.36,;36.25,-37.14,;37.15,-35.9,;38.69,-35.89,;36.24,-34.66,;34.78,-35.14,;33.45,-34.37,;32.12,-35.14,;32.12,-36.68,;30.79,-37.46,;33.45,-37.45,;34.79,-36.67,;33.45,-32.83,;34.79,-32.05,;32.12,-32.05,;33.44,-31.28,)| Show InChI InChI=1S/C16H12ClF4N3O/c1-7-4-13(16(19,20)21)24-15(22-7)14(8(2)23-24)9-5-10(17)12(25-3)6-11(9)18/h4-6H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	479	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283478 (CHEMBL4164141) Show SMILES COc1cc(F)c(cc1Cl)-c1c(C)nn2c(cc(C)nc12)C(F)(F)F |(37.17,-44.14,;38.18,-42.98,;37.7,-41.52,;38.73,-40.37,;38.23,-38.91,;39.26,-37.76,;36.73,-38.6,;35.71,-39.75,;36.19,-41.21,;35.16,-42.36,;36.25,-37.14,;37.15,-35.9,;38.69,-35.89,;36.24,-34.66,;34.78,-35.14,;33.45,-34.37,;32.12,-35.14,;32.12,-36.68,;30.79,-37.46,;33.45,-37.45,;34.79,-36.67,;33.45,-32.83,;34.79,-32.05,;32.12,-32.05,;33.44,-31.28,)| Show InChI InChI=1S/C16H12ClF4N3O/c1-7-4-13(16(19,20)21)24-15(22-7)14(8(2)23-24)9-5-10(17)12(25-3)6-11(9)18/h4-6H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	480	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547313 (CHEMBL4751110) Show SMILES Fc1cc(OC2CCOC2)c2ncc(C#N)c(N3CCN(CC3)c3ccccc3F)c2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	510	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283489 (CHEMBL4168668) Show SMILES COc1cc(F)c(-c2c(C)nn3c(cc(C)nc23)C(F)(F)F)c(F)c1 |(75.94,-28.33,;76.96,-27.18,;76.48,-25.72,;74.97,-25.41,;74.49,-23.95,;72.98,-23.63,;75.51,-22.79,;75.03,-21.33,;75.93,-20.09,;77.47,-20.08,;75.01,-18.86,;73.56,-19.33,;72.23,-18.56,;70.9,-19.33,;70.9,-20.87,;69.56,-21.65,;72.23,-21.64,;73.57,-20.87,;72.23,-17.02,;73.56,-16.25,;70.89,-16.25,;72.21,-15.48,;77.01,-23.11,;78.04,-21.95,;77.51,-24.56,)| Show InChI InChI=1S/C16H12F5N3O/c1-7-4-12(16(19,20)21)24-15(22-7)13(8(2)23-24)14-10(17)5-9(25-3)6-11(14)18/h4-6H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	600	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283489 (CHEMBL4168668) Show SMILES COc1cc(F)c(-c2c(C)nn3c(cc(C)nc23)C(F)(F)F)c(F)c1 |(75.94,-28.33,;76.96,-27.18,;76.48,-25.72,;74.97,-25.41,;74.49,-23.95,;72.98,-23.63,;75.51,-22.79,;75.03,-21.33,;75.93,-20.09,;77.47,-20.08,;75.01,-18.86,;73.56,-19.33,;72.23,-18.56,;70.9,-19.33,;70.9,-20.87,;69.56,-21.65,;72.23,-21.64,;73.57,-20.87,;72.23,-17.02,;73.56,-16.25,;70.89,-16.25,;72.21,-15.48,;77.01,-23.11,;78.04,-21.95,;77.51,-24.56,)| Show InChI InChI=1S/C16H12F5N3O/c1-7-4-12(16(19,20)21)24-15(22-7)13(8(2)23-24)14-10(17)5-9(25-3)6-11(14)18/h4-6H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	603	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283472 (CHEMBL4160748) Show SMILES COc1ccc(-c2c(C)nn3c(cc(C)nc23)C(F)(F)F)c(F)c1F |(9.45,-43.77,;10.47,-42.62,;9.99,-41.15,;8.48,-40.84,;7.99,-39.38,;9.02,-38.23,;8.54,-36.77,;9.43,-35.53,;10.97,-35.52,;8.53,-34.29,;7.07,-34.77,;5.74,-34,;4.41,-34.77,;4.41,-36.31,;3.08,-37.09,;5.74,-37.08,;7.08,-36.3,;5.74,-32.46,;7.08,-31.68,;4.41,-31.68,;5.73,-30.92,;10.52,-38.54,;11.55,-37.39,;11.01,-40,;12.52,-40.31,)| Show InChI InChI=1S/C16H12F5N3O/c1-7-6-11(16(19,20)21)24-15(22-7)12(8(2)23-24)9-4-5-10(25-3)14(18)13(9)17/h4-6H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	646	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547315 (CHEMBL4751175) Show SMILES Fc1cc(OCC2CCOC2)c2ncc(C#N)c(N3CCN(CC3)c3ccccc3F)c2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	650	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283472 (CHEMBL4160748) Show SMILES COc1ccc(-c2c(C)nn3c(cc(C)nc23)C(F)(F)F)c(F)c1F |(9.45,-43.77,;10.47,-42.62,;9.99,-41.15,;8.48,-40.84,;7.99,-39.38,;9.02,-38.23,;8.54,-36.77,;9.43,-35.53,;10.97,-35.52,;8.53,-34.29,;7.07,-34.77,;5.74,-34,;4.41,-34.77,;4.41,-36.31,;3.08,-37.09,;5.74,-37.08,;7.08,-36.3,;5.74,-32.46,;7.08,-31.68,;4.41,-31.68,;5.73,-30.92,;10.52,-38.54,;11.55,-37.39,;11.01,-40,;12.52,-40.31,)| Show InChI InChI=1S/C16H12F5N3O/c1-7-6-11(16(19,20)21)24-15(22-7)12(8(2)23-24)9-4-5-10(25-3)14(18)13(9)17/h4-6H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	650	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547309 (CHEMBL4753189) Show SMILES CC(C)Oc1cc(F)cc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	690	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547309 (CHEMBL4753189) Show SMILES CC(C)Oc1cc(F)cc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	690	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547322 (CHEMBL4745777) Show SMILES Fc1ccccc1N1CCN(CC1)c1c(cnc2c(cccc12)N1CCOCC1)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	708	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 expressed in HEK293 cells co- expressing GIRK assessed as potentiation of L-AP4-induced thallium flux inc...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547322 (CHEMBL4745777) Show SMILES Fc1ccccc1N1CCN(CC1)c1c(cnc2c(cccc12)N1CCOCC1)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	710	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 expressed in HEK293 cells co- expressing GIRK assessed as potentiation of L-AP4-induced thallium flux inc...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283481 (CHEMBL4160675) Show SMILES CCc1nn2c(cc(C)nc2c1-c1cc(F)c(OC(F)F)cc1F)C(F)(F)F |(25.69,-48.74,;24.92,-50.08,;23.38,-50.09,;22.48,-48.85,;21.02,-49.33,;19.69,-48.56,;18.36,-49.33,;18.36,-50.87,;17.03,-51.64,;19.69,-51.64,;21.03,-50.86,;22.49,-51.33,;22.97,-52.79,;21.94,-53.94,;22.43,-55.4,;21.4,-56.55,;23.94,-55.71,;24.42,-57.17,;23.4,-58.33,;23.88,-59.79,;21.89,-58.02,;24.96,-54.56,;24.47,-53.1,;25.5,-51.95,;19.69,-47.02,;21.03,-46.24,;18.36,-46.24,;19.68,-45.48,)| Show InChI InChI=1S/C17H12F7N3O/c1-3-11-14(8-5-10(19)12(6-9(8)18)28-16(20)21)15-25-7(2)4-13(17(22,23)24)27(15)26-11/h4-6,16H,3H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	740	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283481 (CHEMBL4160675) Show SMILES CCc1nn2c(cc(C)nc2c1-c1cc(F)c(OC(F)F)cc1F)C(F)(F)F |(25.69,-48.74,;24.92,-50.08,;23.38,-50.09,;22.48,-48.85,;21.02,-49.33,;19.69,-48.56,;18.36,-49.33,;18.36,-50.87,;17.03,-51.64,;19.69,-51.64,;21.03,-50.86,;22.49,-51.33,;22.97,-52.79,;21.94,-53.94,;22.43,-55.4,;21.4,-56.55,;23.94,-55.71,;24.42,-57.17,;23.4,-58.33,;23.88,-59.79,;21.89,-58.02,;24.96,-54.56,;24.47,-53.1,;25.5,-51.95,;19.69,-47.02,;21.03,-46.24,;18.36,-46.24,;19.68,-45.48,)| Show InChI InChI=1S/C17H12F7N3O/c1-3-11-14(8-5-10(19)12(6-9(8)18)28-16(20)21)15-25-7(2)4-13(17(22,23)24)27(15)26-11/h4-6,16H,3H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	741	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547309 (CHEMBL4753189) Show SMILES CC(C)Oc1cc(F)cc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	750	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 expressed in HEK293 cells co- expressing GIRK assessed as potentiation of L-AP4-induced thallium flux inc...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547309 (CHEMBL4753189) Show SMILES CC(C)Oc1cc(F)cc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	759	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 expressed in HEK293 cells co- expressing GIRK assessed as potentiation of L-AP4-induced thallium flux inc...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547324 (CHEMBL4754102) Show SMILES COc1cccc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	871	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 expressed in HEK293 cells co- expressing GIRK assessed as potentiation of L-AP4-induced thallium flux inc...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547324 (CHEMBL4754102) Show SMILES COc1cccc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	879	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 expressed in HEK293 cells co- expressing GIRK assessed as potentiation of L-AP4-induced thallium flux inc...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547305 (CHEMBL4761695) Show SMILES [2H]C([2H])([2H])Oc1cc(F)cc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	990	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 expressed in HEK293 cells co- expressing GIRK assessed as potentiation of L-AP4-induced thallium flux inc...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283490 (CHEMBL4172016) Show SMILES COc1cc(F)c(cc1F)-c1c(C)nn2c(cc(C)nc12)C(F)(F)F |(24.3,-44,;25.32,-42.84,;24.84,-41.38,;25.87,-40.23,;25.37,-38.77,;26.4,-37.61,;23.87,-38.46,;22.85,-39.61,;23.33,-41.07,;22.3,-42.22,;23.39,-36.99,;24.29,-35.75,;25.83,-35.74,;23.38,-34.52,;21.92,-35,;20.59,-34.22,;19.26,-35,;19.26,-36.54,;17.92,-37.31,;20.59,-37.3,;21.93,-36.53,;20.59,-32.68,;21.92,-31.91,;19.25,-31.91,;20.57,-31.14,)| Show InChI InChI=1S/C16H12F5N3O/c1-7-4-13(16(19,20)21)24-15(22-7)14(8(2)23-24)9-5-11(18)12(25-3)6-10(9)17/h4-6H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547305 (CHEMBL4761695) Show SMILES [2H]C([2H])([2H])Oc1cc(F)cc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 expressed in HEK293 cells co- expressing GIRK assessed as potentiation of L-AP4-induced thallium flux inc...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547312 (CHEMBL4744634) Show SMILES Fc1ccccc1N1CCN(CC1)c1c(cnc2c(OC3CCOC3)cccc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 expressed in HEK293 cells co- expressing GIRK assessed as potentiation of L-AP4-induced thallium flux inc...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283490 (CHEMBL4172016) Show SMILES COc1cc(F)c(cc1F)-c1c(C)nn2c(cc(C)nc12)C(F)(F)F |(24.3,-44,;25.32,-42.84,;24.84,-41.38,;25.87,-40.23,;25.37,-38.77,;26.4,-37.61,;23.87,-38.46,;22.85,-39.61,;23.33,-41.07,;22.3,-42.22,;23.39,-36.99,;24.29,-35.75,;25.83,-35.74,;23.38,-34.52,;21.92,-35,;20.59,-34.22,;19.26,-35,;19.26,-36.54,;17.92,-37.31,;20.59,-37.3,;21.93,-36.53,;20.59,-32.68,;21.92,-31.91,;19.25,-31.91,;20.57,-31.14,)| Show InChI InChI=1S/C16H12F5N3O/c1-7-4-13(16(19,20)21)24-15(22-7)14(8(2)23-24)9-5-11(18)12(25-3)6-10(9)17/h4-6H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547312 (CHEMBL4744634) Show SMILES Fc1ccccc1N1CCN(CC1)c1c(cnc2c(OC3CCOC3)cccc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 expressed in HEK293 cells co- expressing GIRK assessed as potentiation of L-AP4-induced thallium flux inc...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283488 (CHEMBL4171274) Show SMILES CCc1nn2c(cc(C)nc2c1-c1ccc(OC)c(F)c1F)C(F)(F)F |(39.73,-48.22,;38.96,-49.56,;37.42,-49.57,;36.52,-48.33,;35.06,-48.81,;33.73,-48.04,;32.4,-48.81,;32.4,-50.35,;31.07,-51.12,;33.73,-51.12,;35.07,-50.34,;36.53,-50.81,;37.01,-52.27,;35.98,-53.42,;36.47,-54.88,;37.98,-55.19,;38.46,-56.65,;37.44,-57.81,;39,-54.04,;40.51,-54.34,;38.52,-52.58,;39.54,-51.43,;33.73,-46.5,;35.07,-45.72,;32.4,-45.72,;33.72,-44.96,)| Show InChI InChI=1S/C17H14F5N3O/c1-4-10-13(9-5-6-11(26-3)15(19)14(9)18)16-23-8(2)7-12(17(20,21)22)25(16)24-10/h5-7H,4H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547324 (CHEMBL4754102) Show SMILES COc1cccc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283488 (CHEMBL4171274) Show SMILES CCc1nn2c(cc(C)nc2c1-c1ccc(OC)c(F)c1F)C(F)(F)F |(39.73,-48.22,;38.96,-49.56,;37.42,-49.57,;36.52,-48.33,;35.06,-48.81,;33.73,-48.04,;32.4,-48.81,;32.4,-50.35,;31.07,-51.12,;33.73,-51.12,;35.07,-50.34,;36.53,-50.81,;37.01,-52.27,;35.98,-53.42,;36.47,-54.88,;37.98,-55.19,;38.46,-56.65,;37.44,-57.81,;39,-54.04,;40.51,-54.34,;38.52,-52.58,;39.54,-51.43,;33.73,-46.5,;35.07,-45.72,;32.4,-45.72,;33.72,-44.96,)| Show InChI InChI=1S/C17H14F5N3O/c1-4-10-13(9-5-6-11(26-3)15(19)14(9)18)16-23-8(2)7-12(17(20,21)22)25(16)24-10/h5-7H,4H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.05E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547305 (CHEMBL4761695) Show SMILES [2H]C([2H])([2H])Oc1cc(F)cc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547305 (CHEMBL4761695) Show SMILES [2H]C([2H])([2H])Oc1cc(F)cc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547328 (CHEMBL4752850) Show SMILES COc1c(F)c(F)cc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547324 (CHEMBL4754102) Show SMILES COc1cccc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547308 (CHEMBL4759638) Show SMILES CC(C)Oc1cccc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.25E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547322 (CHEMBL4745777) Show SMILES Fc1ccccc1N1CCN(CC1)c1c(cnc2c(cccc12)N1CCOCC1)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547314 (CHEMBL4745281) Show SMILES Fc1ccccc1N1CCN(CC1)c1c(cnc2c(OCC3CCOC3)cccc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547314 (CHEMBL4745281) Show SMILES Fc1ccccc1N1CCN(CC1)c1c(cnc2c(OCC3CCOC3)cccc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547312 (CHEMBL4744634) Show SMILES Fc1ccccc1N1CCN(CC1)c1c(cnc2c(OC3CCOC3)cccc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547314 (CHEMBL4745281) Show SMILES Fc1ccccc1N1CCN(CC1)c1c(cnc2c(OCC3CCOC3)cccc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547322 (CHEMBL4745777) Show SMILES Fc1ccccc1N1CCN(CC1)c1c(cnc2c(cccc12)N1CCOCC1)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547312 (CHEMBL4744634) Show SMILES Fc1ccccc1N1CCN(CC1)c1c(cnc2c(OC3CCOC3)cccc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547327 (CHEMBL4781814) Show SMILES COc1cc(F)cc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283480 (CHEMBL4175784) Show SMILES CCc1nn2c(cc(C)nc2c1-c1ccc(OC(F)F)cc1F)C(F)(F)F |(53.47,-48.39,;52.7,-49.73,;51.16,-49.74,;50.26,-48.5,;48.8,-48.99,;47.47,-48.21,;46.14,-48.99,;46.14,-50.53,;44.81,-51.3,;47.47,-51.29,;48.81,-50.52,;50.27,-50.98,;50.75,-52.45,;49.72,-53.6,;50.21,-55.06,;51.72,-55.37,;52.2,-56.83,;51.18,-57.99,;49.67,-57.67,;51.67,-59.45,;52.74,-54.21,;52.25,-52.75,;53.28,-51.6,;47.47,-46.67,;48.8,-45.9,;46.13,-45.9,;47.45,-45.13,)| Show InChI InChI=1S/C17H13F6N3O/c1-3-12-14(10-5-4-9(7-11(10)18)27-16(19)20)15-24-8(2)6-13(17(21,22)23)26(15)25-12/h4-7,16H,3H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283480 (CHEMBL4175784) Show SMILES CCc1nn2c(cc(C)nc2c1-c1ccc(OC(F)F)cc1F)C(F)(F)F |(53.47,-48.39,;52.7,-49.73,;51.16,-49.74,;50.26,-48.5,;48.8,-48.99,;47.47,-48.21,;46.14,-48.99,;46.14,-50.53,;44.81,-51.3,;47.47,-51.29,;48.81,-50.52,;50.27,-50.98,;50.75,-52.45,;49.72,-53.6,;50.21,-55.06,;51.72,-55.37,;52.2,-56.83,;51.18,-57.99,;49.67,-57.67,;51.67,-59.45,;52.74,-54.21,;52.25,-52.75,;53.28,-51.6,;47.47,-46.67,;48.8,-45.9,;46.13,-45.9,;47.45,-45.13,)| Show InChI InChI=1S/C17H13F6N3O/c1-3-12-14(10-5-4-9(7-11(10)18)27-16(19)20)15-24-8(2)6-13(17(21,22)23)26(15)25-12/h4-7,16H,3H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.48E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283479 (CHEMBL4165248) Show SMILES COc1ccc(cc1F)-c1c(C)nn2c(cc(C)nc12)C(F)(F)F Show InChI InChI=1S/C16H13F4N3O/c1-8-6-13(16(18,19)20)23-15(21-8)14(9(2)22-23)10-4-5-12(24-3)11(17)7-10/h4-7H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547304 (CHEMBL4776732) Show SMILES [2H]C([2H])([2H])Oc1cccc2c(N3CCN(CC3)c3ccccc3F)c(cnc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283491 (CHEMBL1585091) Show SMILES COC(=O)c1ccc(cc1)-n1c(C)cc(C(=O)CSc2ccc(NC(C)=O)cc2)c1C Show InChI InChI=1S/C24H24N2O4S/c1-15-13-22(16(2)26(15)20-9-5-18(6-10-20)24(29)30-4)23(28)14-31-21-11-7-19(8-12-21)25-17(3)27/h5-13H,14H2,1-4H3,(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283479 (CHEMBL4165248) Show SMILES COc1ccc(cc1F)-c1c(C)nn2c(cc(C)nc12)C(F)(F)F Show InChI InChI=1S/C16H13F4N3O/c1-8-6-13(16(18,19)20)23-15(21-8)14(9(2)22-23)10-4-5-12(24-3)11(17)7-10/h4-7H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.51E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547312 (CHEMBL4744634) Show SMILES Fc1ccccc1N1CCN(CC1)c1c(cnc2c(OC3CCOC3)cccc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50547312 (CHEMBL4744634) Show SMILES Fc1ccccc1N1CCN(CC1)c1c(cnc2c(OC3CCOC3)cccc12)C#N Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK293 cells co-expressing Gai5 assessed as potentiation of L-AP4-induced calcium m...				Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00432 BindingDB Entry DOI: 10.7270/Q2ZG6WTX
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 7 (Rattus norvegicus (Rat))	BDBM50283484 (CHEMBL4175868) Show SMILES COc1ccc(-c2c(C)nn3c(cc(C)nc23)C(F)(F)F)c(F)c1 |(62.43,-27.8,;63.45,-26.65,;62.96,-25.18,;61.45,-24.87,;60.97,-23.41,;62,-22.26,;61.51,-20.8,;62.41,-19.56,;63.95,-19.55,;61.5,-18.32,;60.04,-18.8,;58.71,-18.03,;57.38,-18.8,;57.38,-20.34,;56.05,-21.12,;58.71,-21.11,;60.05,-20.33,;58.71,-16.49,;60.05,-15.71,;57.38,-15.71,;58.7,-14.95,;63.5,-22.57,;64.52,-21.42,;63.99,-24.03,)| Show InChI InChI=1S/C16H13F4N3O/c1-8-6-13(16(18,19)20)23-15(21-8)14(9(2)22-23)11-5-4-10(24-3)7-12(11)17/h4-7H,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a
Vanderbilt University Curated by ChEMBL					Assay Description Positive allosteric modulation of rat mGlu7 receptor expressed in HEK cells co-expressing Galphai5 assessed as increase in glutamate-induced calcium ...				ACS Med Chem Lett 8: 1110-1115 (2017) Article DOI: 10.1021/acsmedchemlett.7b00317 BindingDB Entry DOI: 10.7270/Q2B85BN1
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 153 total )  |  Next  |  Last  >>

Jump to: